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All Journal Proceedings of the International Conference on Nursing and Health Sciences International Journal of Medicine and Health Journal of Innovative and Creativity
Kharisma Jayak Pratama
Universitas Duta Bangsa Surakarta
Economics, Econometrics & Finance Education Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Characteristic and Antibacterial Activity Test of Red Betel Leaf Essential Oil Against Propionibacterium Acne Bacteria Bangkit Riska Permata; Kharisma Jayak Pratama; Mei Ika Nurul Khotimah; Sabrina Karim
Proceedings of the International Conference on Nursing and Health Sciences Vol 4 No 1 (2023): January-June 2023
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/picnhs.v4i1.1688

Abstract

Many Indonesian plants have the potential to have anti-acne activity, one of which is the red betel plant. Red betel leaf (Piper crocatum) contains flavonoids, alkaloids, tannins, and essential oils which are thought to be used as antimicrobials. The purpose of this study was to test the quality characteristics and test the antibacterial activity of red betel leaf essential oil against Propionibacterium acne bacteria. This research was an experimental study by identifying the physical quality and testing the antibacterial activity of the essential oil. human senses with the results of the smell or aroma obtained, namely the strong or stinging characteristic odor of red betel. The color of the essential oil obtained was yellow with a little brownish, bitter taste, the pH obtained from the essential oil was 4.65, the specific gravity of red betel leaf essential oil was 0.739, the ethanol soluble test obtained from the essential oil completely dissolved and white clear in a quantity of alcoholic solution. Antibacterial activity test results with red betel leaf essential oil concentrations of 5%, 10%, and 20%, could inhibit antibacterial of 7.16 mm, 10.3 mm, and 11.6 mm.
Formulasi dan Uji Aktivitas Antioksidan Sediaan Face Toner Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) Menggunakan Metode DPPH Rahmadini Rahmadini; Alfina Nurrahman; Kharisma Jayak Pratama
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.8211

Abstract

ABSTRACT Free radicals are unstable molecules that can damage cell membranes, DNA, and proteins, thereby triggering premature aging. Preventive efforts can be carried out through skin care using cosmetic products containing natural antioxidants, which are considered safer and capable of providing long-term protection. One cosmetic product that functions as a moisturizer is face toner. Fragrant pandan leaves (Pandanus amaryllifolius Roxb.) are known to contain antioxidant compounds, making them potential active ingredients in face toner formulations. This study aimed to formulate a face toner containing fragrant pandan leaf extract in three concentration variations, namely 1%, 2%, and 3%. Antioxidant activity was evaluated using the DPPH method to determine IC₅₀ values. Physical quality evaluations were also conducted, including organoleptic tests, homogeneity, pH, and viscosity. The results showed that formula 0 had an IC₅₀ value of 261.11 ppm (very weak), formula 1 had an IC₅₀ value of 51.95 ppm (strong), formula 2 had an IC₅₀ value of 40.32 ppm (very strong), and formula 3 had an IC₅₀ value of 32.91 ppm (very strong). In addition, all formulations (0%, 1%, 2%, and 3%) met the physical quality requirements for cosmetic preparations. Keywords: Antioxidant, Fragrant Pandan Leaves, Extract, Face toner
Relationship of Medication Adherence to Clinical Outcome in Patients Type 2 Diabetes with Modified Morisky Adherence Scale 8 (MMAS 8) Niken Luthfiyanti; Ardi Setyawan; Kharisma Jayak Pratama
International Journal of Medicine and Health Vol. 3 No. 4 (2024): Desember : International Journal of Medicine and Health (IJMH)
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijmh.v3i4.4547

Abstract

Diabetes melitus is a chronic condition desease that requires continued use of medication. High adherence to treatment will produce good clinical results and play a role in improving the quality of life of diabetes melitus sufferers. The following research aims to assess the relationship between adherence to medication use and clinical outcomes for patients with type 2 diabetes mellitus at RSUD DR. Moewardi Surakarta which was conducted in the period April – June 2024. This research used a cross sectional method with a total of 98 patients as respondents who met the inclusion and exclusion criteria. Adherence data was assessed using the Modified Morisky Adherence Scale 8 (MMAS 8) questionnaire, and clinical outcomes were assessed from fasting or fasting blood glucose values ​​and %HbA1C from medical record data. Analysis of the relationship between adherence and clinical outcomes using chi-square. The results of the level of treatment compliance can be divided into 3 categories, namely: high treatment compliance has a percentage of 24.5%, moderate treatment compliance has a percentage of 46.9%, and low treatment compliance has a percentage of 28.6%. Clinical outcomes were achieved by 38.8% and not achieved by 62.2%. There is a relationship between adherence medication and therapeutic outcomes in type 2 diabetes melitus patients with a Pearson chi square value of 0.011. Based on these data, pharmacist professionals need to place greater emphasis on adherence with medication use in type 2 diabetes mellitus patients to obtain good clinical outcomes.
Co-Authors Alfina Nurrahman Ardi Setyawan Bangkit Riska Permata Mei Ika Nurul Khotimah Niken Luthfiyanti Rahmadini Rahmadini Sabrina Karim