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All Journal Jurnal Ilmiah Farmasi BALI MEDICAL JOURNAL (BMJ) INDONESIAN JOURNAL OF LEGAL AND FORENSIC SCIENCES Journal Pharmaceutical Science and Application (JPSA) Jurnal Kimia (Journal of Chemistry) International Journal of Biosciences and Biotechnology Buletin Udayana Mengabdi Jurnal Farmasi Udayana INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Jurnal Biologi Udayana Jurnal Farmasi Klinik Indonesia JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA JURNAL PENDIDIKAN TAMBUSAI Journal of Health Sciences and Medicine Prosiding Workshop dan Seminar Nasional Farmasi (WSNF) Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Medical Laboratory Journal Jurnal Kefarmasian Indonesia Jurnal Farmasi Galenika
Rini Noviyani
Department Of Pharmacy, Faculty Of Mathematics And Sciences, Udayana University
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

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DIFFERENCE OF SGOT AND SGPT LEVEL IN STADIUM IIB-IIIB SQUAMOUS CELL CERVICAL CANCER PATIENTS BEFORE AND AFTER CHEMOTHERAPY AT SANGLAH HOSPITAL DENPASAR R. Noviyani
Journal of Health Sciences and Medicine Vol 2 No 1 (2018): JHSM (February 2018)
Publisher : Institute for Research and Community Services Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (165.482 KB)

Abstract

Objective:Cervical cancer became Indonesia’s highest prevalent gynecological cancer in 2013 and the highest prevalent gynecological cancer at Sanglah Hospital.Paclitaxel Carboplatin is one of the regimens used for cervical cancer treatment at Sanglah Hospital, Denpasar. Aside of providing therapeutic effect, this regimen also causes hepatotoxicity. This research was trying to determine the toxic effect of Paclitaxel Carboplatin towards liver function based on the difference of SGOT and SGPT levels before chemotherapy cycle I and after chemotherapy cycle VI. Method:This wasa prospective observational research with a study case method conducted from January 2017 until June 2017 at Obstetric Polyclinic of Sanglah Hospital, Denpasar.Samples’ SGOT and SGPT level before and after chemotherapy I and VI were recorded and were then analysed with Shapiro-Wilk normality test. If the data were distributed normally, they would undergo tpaired test and Wilcoxon test at 95% confidence level if they were not distributed normally. Results: Tenpatients fulfilled the research criteria. There was a meaningless increase for SGOT level (p=0.575) along with a meaningless increase for SGPT level (p=0.074) before and after Paclitaxel Carboplatin chemotherapy cycle I and VI respectively.Conclusion: Research of toxic effect from Paclitaxel Carboplatin chemotherapy in 10 squamous cell cervical cancer patients showed a meaningless difference of both SGOT and SGPT level with the value of p>0.05 in stadium IIB-IIIB squamous cell cervical cancer patients before and after Paclitaxel Carboplatin chemotherapy cycle I and VI respectively.
COST ANALYSIS OF PATIENTS WITH SQUAMOUS CELL CERVICAL CANCER STAGE IIB-IIIB WITH PACLITAXEL CISPLATIN CHEMOTHERAPY FROM THE SOCIETAL PERSPECTIVE Ni Kd Rintan Listiani Ekayanti; Rini Noviyani; Sagung Chandra Yowani; Ketut Ariawati; I Nyoman G. Budiana
Journal Pharmaceutical Science and Application Vol 5 No 1 (2023): Journal Pharmaceutical Science and Application (JPSA)
Publisher : Departement of Pharmacy, Faculty of Mathematic and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JPSA.2023.v05.i01.p05

Abstract

Background: The high prevalence of cervical cancer patients and the variety of necessary expenses needed causing financial hardship to both the patient and hospital. Furthermore, the disparity between the INA-CBGs rates and the costs of treatment incurred by hospitals and the limited information regarding the costs of cervical cancer undergoing cisplatin paclitaxel chemotherapy as viewed from a societal perspective were the reasons to conduct this research. Objective: The aim of this study was to determine the cost of squamous cell cervical cancer patients at stage IIB-IIB who received cisplatin paclitaxel chemotherapy from a social perspective. So in this study the difference in costs is used to calculate costs from a hospital perspective. Methods: This research was an observational study with a prospective incidence approach and consecutive sampling as the sampling method. This research was conducted from January to June 2017 at Sanglah General Hospital, Denpasar. Cost data from a societal perspective for six chemotherapy series were obtained from the Claim Guarantee Installation, Fund Mobility Section, interviews and filling in the logbook by patients and then calculated using the micro-costing method. Results: The results of this study obtained five patients who met the inclusion criteria. From the perspective of BPJS Kesehatan, the average cost of cervical cancer with paclitaxel cisplatin chemotherapy was IDR 24.703.470,00. From a hospital perspective, the average cost of cervical cancer with paclitaxel cisplatin chemotherapy was IDR 6.619.204,00., and from the perspective of patients and their families, the average burden of costs for cervical cancer with paclitaxel cisplatin chemotherapy was IDR 9.149.300,00. Conclusion: Cost analysis on five squamous cell cervical cancer patients with stage IIB-IIIB with six series of paclitaxel cisplatin chemotherapy viewed from the perspective of BPJS Kesehatan, hospital was IDR 24,703,470.00, IDR 6,619,204.00, and IDR 9,149,300.00, respectively. Keywords: Cervical Cancer; Chemotherapy; Cost Analysis; Paclitaxel Cisplatin; Societal Perspective
Penyusunan Standard Operating Procedure (SOP) Evaluasi Perencanaan Perbekalan Kefarmasian di Rumah Sakit X Gusti Ayu Putu Prima Purnamasari; Rini Noviyani
Indonesian Journal of Legal and Forensic Sciences (IJLFS) Vol 13 No 1 (2023): Indonesian Journal of Legal and Forensic Sciences
Publisher : Penerbit, sejak 2012 : Asosiasi Ilmu Forensik Indonesia dan UPT Lab. Forensik Sain dan Kriminilogi - Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/IJLFS.2023.v13.i01.p04

Abstract

Hospital Pharmacy Services is a health service that focuses on patients in providing quality, quality and affordable Pharmaceutical Preparations, Medical Devices, and Medical Consumables for the community. To ensure that pharmaceutical supplies are in accordance with the required quality and specifications, a planning process is necessary. From the results of interviews that have been carried out, that Hospital X has not evaluated the planning but is only planning to look at the disease pattern from the previous period. To overcome problems in the field, the preparation of Standard Operating Procedures (SOP) for evaluating pharmaceutical supply planning is carried out. Evaluation methods that can be used in planning are the ABC, VEN and PUT (ABC-VEN Combination) methods. Based on the Minister of Health Regulation Number 72 of 2016 the preparation of the SOP that has been made almost resembles the applicable laws and regulations and can be implemented properly at Hospital X so as to achieve adequate drug availability.
Pemanfaatan Ikan Gabus (Channa striata) dalam Pengobatan Osteoarthritis A.A Ayu Dessy Satriani Putri; Sita Udayanti; Putu Ita Purnama Dewi; Rini Noviyani
Prosiding Workshop dan Seminar Nasional Farmasi Vol. 1 (2022): Prosiding Workshop dan Seminar Nasional Farmasi 2022
Publisher : Program Studi Farmasi Fakultas MIPA Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/WSNF.2022.v01.i01.p03

Abstract

Penyakit degeneratif merupakan penyakit yang sering terjadi pada proses penuaan. Di seluruh dunia, jumlah penyakit degeneratif terus bertambah. Salah satu penyakit degeneratif yang sering dialami yaitu osteoarthritis. Di Indonesia, prevalensi osteoarthritis adalah 7,30% dan bertambahnya usia maka angka kejadian osteoarthritispun semakin tinggi, dimana pada usia 45-54 tahun terjadi 11,08%, usia diatas 75 tahun sebesar 18,85%. Untuk menghilangkan nyeri osteoarthritis, digunakan obat nonsteroid antiinflamasi (NSAID) dan NSAID spesifik COX-2 akan tetapi terapi farmakologis ini kurang optimal dan memiliki efek samping. Akibatnya, pengobatan komplementer dan alternatif semakin populer maka digunakan obat herbal yang bersumber dari ikan salah satunya adalah ikan gabus (Channa striata). Ikan gabus dipercaya dapat mengurangi pembengkakan pada osteoarthritis dikarenakan efek antiinflamasi, analgesik dan penyembuhan luka. Tujuan review artikel ini adalah untuk mengetahui pemanfaatan ikan gabus dalam pengobatan osteoarthritis. Metode yang digunakan pada pembuatan artikel review ini yaitu studi pustaka atau literatur. Pustaka atau literatur yang digunakan merupakan jurnal nasional maupun internasional yang membahas mengenai penggunaan ikan gabus untuk pengobatan osteoarthritis yang dipublikasikan secara online dari berbagai situs seperti Google Scholar, Science Direct, Researchgate, Pubmed, dan Springerlink. Hasil menunjukkan bahwa ikan gabus (Channa striata) dapat mengurangi pembengkakan jaringan lunak sendi dan juga mengurangi kepadatan protein gen produk (PGP) 9.5- imunoreaktif serabut saraf di membran sinovial. Pemberian ekstrak Channa striata bisa menjadi alternatif baru untuk pengobatan osteoarthritis, karena aman dan terkait dengan pengurangan nyeri yang signifikan secara statistik, perbaikan gejala, dan kualitas hidup pada pasien dengan osteoarthritis.
Pemanfaatan Ekstrak Ikan Gabus (Channa striata) untuk Penyembuh Luka pada Pasien Diabetes Mellitus (Ulkus Diabetikum) Sita Udayanti; Rini Noviyani
Prosiding Workshop dan Seminar Nasional Farmasi Vol. 1 (2022): Prosiding Workshop dan Seminar Nasional Farmasi 2022
Publisher : Program Studi Farmasi Fakultas MIPA Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/WSNF.2022.v01.i01.p05

Abstract

Diabetes melitus merupakan penyakit metabolisme karbohidrat yang membuat penederita mengalami kenaikan kadar glukosa darah yang disebabkan sekresi insulin. Penderita diabetes melitus rentang dengan adanya komplikasi ulkus diabetikum (luka diabetes). Di Indonesia, prevalensi ulkus diabetikum bagian ekstremitas bawah sebanyak 76,63% dan bagian ekstremitas atas sebanyak 23,37%. Salah satu cara untuk mempercepat penyembuhan luka dan menjaga kestabilan gula darah adalah dengan melakukan perawatan kaku secara rutin dengan menggunakan ekstrak ikan gabus (Channa striata). Ikan ini memiliki banyak khasiat seperti mempercepat pentembuhan luka dan sebagai antiinflamasi. Penyusunan artikel ini untuk mengetahui pemanfaatan dari penggunaan ikan gabus sebagai penyembuhan luka pada diabetes melitus. Metode yang digunakan dalam penyusunan artikel review ini yaitu studi pustaka. Pustaka yang digunakan merupakan jurnal nasional maupun internasional yang membahas mengenai penggunaan ikan gabus untuk penyembuhan luka pada diabetes melitus yang diterbitkan secara online dari berbagai situs seperti Science Direct, Google Scholar, Pubmed, dan Elsevier. Hasil menunjukkan bahwa ikan gabus (Channa striata) mampu mempercepat proses penyembuhan luka pada beberapa percobaan yang telah dilakukan, baik menggunakan hewan uji maupun langsung diberikan kepada pasien post operasi. Salah satu hasil penelitian yang dilakukan dengan menggunakan pasien penderita ulkus diabetikum sebagai kelompok control sebanyak 16 orang yang menerima perawatan standar NaCl 0,9% selama 21 hari dan kelompok intervensi sebanyak 16 orang yang menerima hydrogel ekstrak ikan gabus dosis 675.675 selama 21 hari. Diperoleh hasil bahwa pemberian ekstrak ikan gabus kepada pasien ulkus diabetikum pada kelompok intervensi efektif untuk mempercepat proses penyembuhan luka. Dari studi pustaka dapat disimpulkan bahwa ikan ini dapat dimanfaatkan untuk membantu proses penyembuhan luka.
Kajian Sistematik: Efek Gen Multi Drug Resistance-1 pada Farmakokinetik Klopidogrel Niruri, Rasmaya; Noviyani, Rini; Rahajeng, indah Mei
Jurnal Kefarmasian Indonesia VOLUME 9, NOMOR 1, FEBRUARI 2019
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v9i1.584

Abstract

Multi Drug Resistance-1 (MDR-1) gene polymorphisms encoding for P-glycoprotein can affect clopidogrel intestinal absorption. This systematic review aim to identify the impact of MDR-1 gene 3435 variants on clopidogrel pharmacokinetics. Literature review were retrieved from MEDLINE, Science Direct, Scopus, Clinical Key, ProQuest and Google Scholar databases. The articles are critically reviewed and analyzed to answer this systematic review’s aim. The result showed that, in patients with cardiovascular disease, the peak plasma concentration (Cmax) and the total area under the plasma concentration–time curve (AUC) of clopidogrel and its active metabolites were lower in 3435TT compared to 3435CC. Nevertheless, the variants of MDR-1 gene were not significantly correlated to the plasma concentration in healthy subjects. Clopidogrel pharmacokinetic profile varied widely between MDR-1 3435 variants and subjects.
Evaluation of Standard Procedures Operational in Tabanan District General Hospital: Usage of Special Control Antimicrobials (Restrictions) Noviyani, Rini; Putri, A. A. Sagung Indah Candra; Putri, Ni Wayan Prasanthi Swarna; Ekayanti, Ni Kd Rintan Listiani; Widatama, Agata
Jurnal Ilmiah Farmasi Vol. 20 No. 2 (2024): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol20.iss2.art2

Abstract

Background: The healthcare sector, specifically hospitals, is vulnerable to antimicrobial resistance due to diverse services and patient populations, alongside continuous intensive antimicrobial use. This resistance presents a significant national and global health threat. Therefore, implementing an antimicrobial stewardship program is crucial for reducing resistance development and spread in hospitals. Pharmacists, as healthcare professionals, have an essential role in upholding stewardship through pharmaceutical services in line with Standard Operating Procedure (SOP).Objective: This study aimed to evaluate Restricted Antimicrobial Standard Operating Procedure (SOP-A) at Tabanan Regional General Hospital (RSUD Tabanan) to enhance the quality of pharmaceutical services.Method: A qualitative method was used in SOP evaluation, comparing data from interviews with the Head of Pharmacy Installation at RSUD Tabanan and observations of implementation. The data were then contrasted with recent literature and regulations to identify discrepancies necessitating improvements. Moreover, data were analyzed using the descriptive method and presented in narrative, figure, and table formats.Results: The results showed that based on interviews and observations of SOP-A implementation, several revisions were needed. These revisions include adding restricted antimicrobials from the reserve categories (cefepime, cefpirome, and carbapenems), establishing a protocol for eligible patients without waiting for culture results, outlining a process for obtaining approval from the Head of the Antimicrobial Resistance Control Program (PPRA) and Hospital Director, as well as incorporating antimicrobial usage history into the restricted antibiotic use application form.Conclusion: SOP-A at RSUD Tabanan requires four key additions, namely a list of reserve category antimicrobials, a protocol for administering restricted antimicrobials to eligible patients without waiting for culture results, a process for obtaining approval from the Head of the PPRA and Hospital Director, as well as inclusion of antimicrobial usage history in the restricted antibiotic use application form.
Potassium Profile in Heart Failure Patients Before and After Hospitalization at Prof. Dr. I.G.N.G. Ngoerah Hospital Kadek Indra Aryani; Ni Putu Ika Swastiartha; Ni Komang Ayu Krisma Suriatha Putri; Ni Kadek Mas Ari Pratiwi; Made Suta Wahyudi; Rini Noviyani
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 12 No. 1 (2025): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v12i12025.37-49

Abstract

Background: Hypokalemia in patients with heart failure is increasing, with an increasing incidence of 6.8% in Asia and 19.7% in Indonesia; globally, 63 million people suffer from heart failure. Hypokalemia is defined as a serum potassium level below 3.5 mEq/L [mmol/L], which can lead to decreased heart function, muscle weakness, arrhythmias and cardiac arrest. The use of diuretic drugs such as furosemide in heart failure patients may be a risk factor for hypokalemia. Objective: This study aims to determine the difference in potassium levels before and after furosemide administration as well as the possibility of hypokalemia due to furosemide administration in inpatients diagnosed with heart failure at Prof. Dr. I.G.N.G. Ngoerah Hospital. Methods: This is a cross-sectional observational study with retrospective medical record collection. The minimum sample size was calculated using Lemeshow's Formula of One Proportion Estimation Method with Absolute Precision Proportion, data normality test with Kolmogorov-Smirnov (p>0.05) and parametric test with paired t-test (p<0.05). This study included 101 patients that met the inclusion criteria with 11 patients having more than one inpatient visit, so a total 114 'patients' medical records were obtained. Results: Potassium levels before and after hospitalization showed a significant difference (p<0.05). A total of 84 'patients' data showed a decrease in potassium levels, with 49 of them showing a reduction in >15% and 35 showing a decrease of ≤15%. Conclusion: Prevalence of hypokalemia in patients with a diagnosis of heart failure and furosemide therapy at Prof. Dr. I.G.N.G. Ngoerah Hospital during January 2022-December 2023 after hospitalization was 29%.
Tinjauan Sistematis : Efektivitas Kapsul Ikan Gabus (Channa striata) terhadap Peningkatan Kadar Albumin pada Pasien Hipoalbuminemia Putu Alin Michelle Arisanti; Rini Noviyani
Medical Laboratory Journal Vol. 3 No. 2 (2025): June : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v3i2.735

Abstract

Hypoalbuminemia is an abnormal condition indicated by low albumin levels, which is <3.5 g/dL and is commonly found in patients with chronic diseases. Conventional therapy through Human Serum Albumin (HSA) is often an option, but has limitations, including fornas restrictions, very high costs, and limited availability. Thus, other more effective and efficient alternatives are needed, namely by utilizing biological sources such as snakehead fish in the form of supplements or capsules. Although there have been various studies and clinical evidence regarding its effectiveness, literature reviews that tabulate the results of various studies are still very limited. Therefore, this systematic review needs to be written to determine the effectiveness of administering snakehead fish capsules on albumin levels in patients with hypoalbuminemia. The compilation of this literature review uses a literature review method that is presented descriptively using several databases that meet the inclusion and exclusion criteria that have been set. The final result obtained 12 literatures that met the inclusion criteria for further study. The results of the review consistently showed that capsules or supplementation of snakehead fish extract were proven to be significantly effective in increasing albumin levels in patients. Factors that influence the effects of administering snakehead fish capsules are the dose and frequency of administration. It was revealed that intervention for 21 days provided superior albumin increase results compared to a duration of 10-14 days. This finding is very relevant because it is in accordance with the biological half-life of albumin in the liver, which is around 21 days. This literature review is expected to be a strong scientific basis for further research and the development of more effective clinical policies in the future.  
Potensi Suplementasi Spirulina (Arthrospira sp.) sebagai Obat Herbal Agen Kardioprotektif Ni Komang Ayu Krisma Suriatha Putri; Rini Noviyani
Prosiding Workshop dan Seminar Nasional Farmasi Vol. 3 (2024): Prosiding Workshop dan Seminar Nasional Farmasi 2024
Publisher : Program Studi Farmasi Fakultas MIPA Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/WSNF.2024.v03.p13

Abstract

Penyakit kardiovaskular merupakan salah satu penyakit yang dapat menyebabkan kematian global. Penyakit kardiovaskular menurut data World Health Organization (WHO) tahun 2019 merupakan penyebab kematian sebesar 32%, yakni sebanyak 17,9 juta jiwa. Penyakit kardiovaskular adalah kelompok penyakit yang terjadi akibat adanya gangguan pada jantung dan pembuluh darah. Perkembangan penyakit kardiovaskular disebabkan oleh beberapa faktor, seperti interaksi faktor genetik individu, lingkungan, dan pilihan gaya hidup individu. Salah satu upaya pencegahan yang dapat dilakukan adalah dengan pemberian penunjang berupa obat herbal atau suplemen herbal. Spirulina atau Arthrospira sp. merupakan salah satu contoh tumbuhan yang sudah banyak dijadikan suplemen herbal yang penting bagi kesehatan dan memiliki berbagai aktivitas farmakologi, salah satunya adalah sebagai agen kardioprotektif. Tujuan dari penelitian ini adalah untuk mengkaji potensi suplementasi spirulina (Arthrospira sp.) sebagai obat herbal agen kardioprotektif. Metode pembuatan artikel dilakukan dengan bentuk literature review atau kajian pustaka ilmiah dengan melakukan penelusuran artikel secara online pada database PubMed, ScienceDirect, dan Google Scholar. Artikel yang memenuhi kriteria inklusi dipilih dengan meninjau judul, abstrak, dan hasil artikel lalu dianalisis secara naratif. Hasil penelitian menunjukkan bahwa ditemukannya potensi suplementasi spirulina (Arthrospira sp.) sebagai obat herbal agen kardioprotektif, dikarenakan memiliki aktivitas sebagai penurun konsentrasi lipid dan kolesterol, penurun gula darah, penurun efek kardiotoksisitas, antioksidan, antitrombotik, antiinflamasi, dan antihipertensi.
Co-Authors A.A Ayu Dessy Satriani Putri A.A. Raka Karsana AA Agustia Sinta Dewi Allysia Maria Vianney Putri Anak A. A. W. P. Dewi Budiana, Nyoman Desak Made Dewi Diantari Dewa Ayu Swastini Dewi, Anak A. A. W. P. Ekayanti, Ni Kd Rintan Listiani F.S. Suherman G.A. Desya Pradnyaswari Gusti Ayu Putu Prima Purnamasari I Ketut Suwiyoga I Ketut Tunas I Nyoman G. Budiana I Nyoman Gede Budiana I Nyoman Gede Piliarta I Putu Triyasa I. F. W. Putra I. Lesmana Indah Mei Rahajeng Intan Puspa Kadek Indra Aryani Ketut Ariawati Ketut Widyani Astuti Komang Dian Aditya Putra Luh Putu Mirah Kusuma Dewi Made Suta Wahyudi Mahardika Aprilia Iflahah Ni Kadek Mas Ari Pratiwi Ni Kd Rintan Listiani Ekayanti Ni Komang Ayu Krisma Suriatha Putri Ni Luh Dian Senja Pratiwi Ni Luh Putu Taksayani Putri Ni Made Intan Pertiwi Ni Putu Ariantari Ni Putu Ika Swastiartha Pande Ketut Astri Utami Puspa, Intan Putri, A. A. Sagung Indah Candra Putri, Ni Wayan Prasanthi Swarna Putu Alin Michelle Arisanti Putu Ayu Indrayathi Putu Ita Purnama Dewi R. Niruri Rasmaya Niruri Rasmaya Niruri Rasmaya Niruri Rasmaya Niruri Sagun Chandra Yowani Sagung Chandra Yowani Sari Mynarti Sita Udayanti Wicaksana, I Nyoman Arya Nugraha Widatama, Agata