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All Journal Dentika Dental Journal Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Padjadjaran Journal of Dental Researchers and Students

Indra Mustika SP, Indra

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Author-ID : 614415

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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The effectiveness of mangosteen rind extract as additional therapy on chronic periodontitis (Clinical trials) Hendiani, Ina; Hadidjah, Dede; Susanto, Agus; Setia Pribadi, Indra Mustika
Padjadjaran Journal of Dentistry Vol 29, No 1 (2017): March 2017
Publisher : Universitas Padjadjaran

Introduction: Periodontitis is an inflammatory disease that attacks the periodontal tissue comprises the gingiva, periodontal ligament, cementum and alveolar bone caused mainly by plaque bacteriophage or other specific dominant type of bacteria. The purpose of this study was to determine the therapeutic effect of clinical application of mangosteen peel extract gel as adjunctive therapy scaling and root planing in patients with chronic periodontitis. This research was expected to developed new treatment in the field of dentistry, particularly in periodontics, which can be used as supporting material for the treatment of chronic periodontitis. Methods: Quasi-experimental research, split mouth, with as many as 14 chronic periodontitis patients. Mangosteen rind was prepared to be formed into extract gel, dried at room temperature, then the dried samples were macerated by using ethanol, then evaporated and decanted for 3 days until obtained condensed extract. The samples were patients with chronic periodontitis in at least 2 teeth with pockets ≥ 5 mm. Clinical parameters of pocket depth, gingival bleeding, and clinical epithelial attachment level were measured at baseline and 1 month after treatment. Analysis of data using the t-test. Results: The comparison of average gap ratio of pockets depth, gingival index, gingival bleeding and epithelium attachment levels, before and after treatment showed significant differences, such as in the test and control sides. Conclusion: The mangosteen rind gel as adjunctive therapy for scaling and root planing is able to reduce pockets depth, gingival index, and gingival bleeding, and improve clinical epithelial attachment.

Validation and reliability of Oral Health Impact Profile-14 questionnaire among pregnant woman Suwargiani, Anne Agustina; Pribadi, Indra Mustika Setia; Hidayat, Wahyu; Yasrin, Tadeus Arufan
Padjadjaran Journal of Dentistry Vol 28, No 2 (2016): July 2016
Publisher : Universitas Padjadjaran

Introduction: The impact of oral health on quality of life of pregnant woman can be measured with the Oral Health Impact Profile-14 (OHIP 14). OHIP 14 is a measuring instrument that measures the functional limitations, physical pain, psychological discomfort, physical disability, psychological disorders, social disorder and disability. validity and reliability of a questionnaire is needed to measure the impact of dental health. The objectives of this study was to get the data validity and OHIP14 questionnaire reliability in pregnant woman. Methods: The research material that OHIP questionnaire 14 that has been adapted to the language and culture of Indonesia. Analysis of the questionnaire on the validity and reliability used correlation test. Research conducted by accidental sampling. Population study was pregnant woman who went to the beauty clinic in Banjaran District of Bandung. Sample study was pregnant woman. The inclusion criteria of sample is in good general state of health, exclusion criteria that do not have a systemic disorder. Result: Validity OHIP14 is the value of R calculated in the range from 0.495 to 0.647, r value calculated in 95% confidence level is 0.374 and in 99% confidence level is 0.474. The coefficient of reliability of 14 item instrument is 0.944. Conclusion: 14 OHIP questionnaire given to pregnant woman to be stated is valid and reliable.

The efficacy of miswak (Kayu sugi) containing toothpaste on dental plaque accumulation Rusminah, Nunung; Pribadi, Indra Mustika Setia; Thillainathan, Komala
Padjadjaran Journal of Dentistry Vol 30, No 1 (2018): March 2018
Publisher : Universitas Padjadjaran

Introduction: Salvadora persica, also known as miswak (Kayu sugi), has been used as natural toothbrushing compound for centuries. Many research suggested that it contains medically beneficial properties such as abrasives, antiseptics, astringent, detergent, enzyme inhibitors, and fluoride. The objective of this study was to assess the efficacy of miswak containing toothpaste on dental plaque accumulation. Methods: The total of 30 subjects consisted of male students of Bandung Institute of Technology, aged between 18 – 26 years old. The plaque value was measured using the Turesky Gilmore & Glickman Index Modification of Quigley & Hein at baseline (day 0), day 1, day 3, and day 7. Commercial toothpaste (Pepsodent®) was used as the control group in this pre and post-test designed, single-blind study. Results: After analysed using the paired t-test, the data showed that the mean plaque index of respondents using miswak and non-miswak containing toothpaste from baseline until day 7, were 1.70/1.19 and 1.61/1.44 respectively (p < 0.05). The mean plaque index reduction of respondents using miswak and non-miswak containing toothpaste from baseline until day 7, were 0.39 and 0.25 respectively (p = 0.00). Conclusion: Both kinds of toothpaste were able to reduce plaque, but miswak containing toothpaste was found to be more effective in reducing dental plaque accumulation.

Inhibitory and bactericidal power of mangosteen rind extract towards Porphyromonas Gingivalis and Actinobacillus Actinomycetemcomitans (Laboratory test) Hendiani, Ina; Hadidjah, Dede; Susanto, Agus; Mustika SP, Indra
Padjadjaran Journal of Dentistry Vol 28, No 2 (2016): July 2016
Publisher : Faculty of Dentistry Universitas Padjadjaran

Introduction: The bacteria that cause the occurrence of pathogens of periodontal disease are gram negative anaerobes. These bacteria include Pophyromonas Gingivalis and Actinobacillus Actinomycetemcomitans. Mangosteen skin extract is known to have anti-inflammatory, anti microbial, and anti oxidant properties. The extract of the mangosteen peel is altered in gel preparation in order to streamline its clinical application in periodontal disease. The purpose of this study was to examine the antibacterial power of the ginger mangosteen tree extract gel against Pophyromonas gingivalis and Actinobacillus Actinomycetemcomitans (Aggregatibacter Actinomycetemcomitans). Methods: This research was conducted by experimental laboratory. Mangosteen fruit extract gel with concentration of 100%, 50%, 25%, 12,5%, 6,25%, 3,125% and 0,78% were tested against Pophyromonas Gingivalis and Aggregatibacter Actinomycetemcomitans with agar diffusion method. Results: The results of this study indicate that for Actinobacilus Aggregatibacter bacteria minimal inhibitory concentration at a concentration of 6.25% with a diameter of 13,5mm inhibition. Minimal bactericidal concentration at 12,5% concentration with 14,7mm inhibitory diameter. In the test of Pophyromonas Gingivalis bacteria, minimal inhibitory concentrations were obtained at a concentration of 1.56% and a minimum bactericidal concentration was obtained at a concentration of 3.125%. Conclusion: The conclusion that mangosteen peel skin gel extract can inhibit bacterial growth and is bactericidal against Pophyromonas Gingivalis and Actinobacillus Actinomycetemcomitans (Aggregatibacter Actinomycetecomitans).

Profile of oral manifestations, oral hygiene, and nutritional status in pregnant women Hidayat, Wahyu; Pribadi, Indra Mustika Setia; Zakiawati, Dewi; Suwargiani, Anne Agustina
Padjadjaran Journal of Dentistry Vol 31, No 3 (2019): November 2019
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol31no3.23792

Introduction: The pregnancy condition leads to few changes in women’s bodies, such as hormonal, physiological, and diet. These changes also manifest in dental and oral health. Hormonal changes affect the susceptibility of oral mucosal tissue, whereas emotional and dietary changes alter the pattern of dietary intake, dental cleaning, oral hygiene, and nutritional status. The purpose of this study was to discover the profile of oral manifestations, oral hygiene, and nutritional status in pregnant women. Methods: The population of the study was the pregnant women who visited the Garuda Community Health Centre in Bandung. Subjects were pregnant women aged 17-43 years old. The samples must meet the inclusion criteria of good health status, and the exclusion criteria were no systemic abnormalities, and not currently under long-term antibiotic therapy. The research design was a cross-sectional observation. Indicators measured in this survey were the profiles of oral manifestations, oral hygiene status which assessed using OHI-S, and nutritional status of pregnant women using haemoglobin (Hb) and Body Mass Index (BMI) level. Results: Oral manifestations found in pregnant women were tongue disorders and ulceration, with the coated tongue as the most frequently detected manifestation, and the least found was recurrent aphthous stomatitis, whereas the oral hygiene of pregnant women was categorised as good in the 1st and 2nd-trimester of pregnancy. However, it was found to be moderate in the 3rd trimester. In respect of the Hb level, the nutritional status of the pregnant women was averagely good. By contrast, the BMI score revealed that pregnant women was found of having overweight during the 2nd and 3rd trimester. Conclusion: The most frequently found oral manifestation in pregnant women is coated tongue, while the oral hygiene is categorised as good on the first two trimesters, and the nutritional status in the last two trimesters is considered as overweight.Keywords: Oral manifestation, oral hygiene, nutritional status.

The effect of carbonate apatite membrane gelatin application on IL-1β level gingival crevicular fluid in chronic periodontitis patients Pribadi, Indra Mustika Setia; Hendiani, Ina; Sartiono, Reynaldy
Padjadjaran Journal of Dentistry Vol 31, No 3 (2019): November 2019
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol31no3.23930

Introduction: Apatite carbonate material plays an important role in bone tissue regeneration. The use of this membrane is expected to achieve better treatment success than those without additional therapy. The antimicrobial content in the apatite carbonate membrane can be used to support periodontal treatment of chronic periodontitis after scaling and root planing. The purpose of this research was to analyse the effect of carbonate apatite membrane gelatin application on the IL-1β level of the gingival crevicular fluid in chronic periodontitis patients. Methods: This research was a double-blind, randomised controlled trial method, with purposive sampling, and split-mouth design. The parameter was the IL-1β level in the gingival crevicular fluid before and after scaling and root planing. Carbonate apatite membrane gelatin was applied to the periodontal pocket on the test group after scaling and root planing. Data were analysed by the Wilcoxon test with a p-value < 0.05. Results: The reduction of IL-1β level gingival crevicular fluid on day-0 and day-30 on both groups showed significant value (p < 0.001). However, it showed no significant differences statistically, between the test group and the control group. Conclusion: Carbonate apatite membrane gelatin application might reduce the IL-1β level of the gingival crevicular fluid, but not showing a better reduction from the control group.Keyword: Carbonate apatite membrane gelatin, IL-1β, periodontal therapy

Co-Authors Agus Susanto Anne Agustina Suwargiani Cucu Zubaedah, Cucu Dede Hadidjah, Dede Dewi Zakiawati, Dewi Endah Mardiati, Endah Faruchy, Annisa Ghea Ina Hendiani, Ina Ira Komara, Ira Jasrin, Tadeus Arufan Nunung Rusminah Pratiwi, Annisa Rizky Riana Wardani Saputra, Sintia Sartiono, Reynaldy Tadeus Arufan Yasrin, Tadeus Arufan Thillainathan, Komala Thillainathan, Komala Wahyu Hidayat Wiwik Handayani Yanti Rusyanti, Yanti Yuti Malinda

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