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All Journal Jurnal Farmasi Udayana Jurnal Kedokteran Brawijaya BIOTROPIA - The Southeast Asian Journal of Tropical Biology Pharmaciana: Jurnal Kefarmasian Jurnal Farmasi Klinik Indonesia Jurnal Farmasi Sains dan Komunitas Jurnal Surya Medika JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Majalah Farmaseutik Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) JFIOnline Jurnal Ilmu Kefarmasian Indonesia Jurnal Farmasi Higea Cendekia Journal of Pharmacy Abdimas Altruis: Jurnal Pengabdian Kepada Masyarakat Jurnal Farmasetis Jurnal Pengabdian Kepada Masyarakat: Kesehatan (JPKMK) Borneo Journal of Pharmacy
Dita Maria Virginia
Sanata Dharma University
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Majalah Farmaseutik

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Drug Interaction Study of Antihypertension in Geriatric Patients Diagnosed Hypertension at Puskesmas Mauponggo, Nusa Tenggara Timur Virginia, Dita Maria; Jago Uko, Maria Anjeline
Majalah Farmaseutik Vol 20, No 2 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v20i2.84773

Abstract

Hypertension is one of the main causes of mortality and morbidity in Indonesia. Treatment of hypertension in geriatric patients has the potential to increase the risk of drug-drug interactions because geriatric patients tend to experience polypharmacy. This study aims to analyze differences in mean blood pressure based on the interaction of antihypertensive drugs with other therapies in geriatric patients who suffer from hypertension at the Mauponggo Health Center, Nagekeo, East Nusa Tenggara. This research is a type of analytic observational research using a research design cross sectional. Data collection was carried out retrospectively. Data was collected using medical records collected from January to December 2021. In this study, a sample of 101 patients was obtained who met the predetermined inclusion and exclusion criteria. Data analysis using unpaired T test to analyze the difference of mean blood pressure based on the presence of antihypertensive drug interactions in geriatric patients, regarding on a significance level of p<0.05. The results showed that drug interactions had no effect on the mean systolic (p-value 0.063), or average diastolic (pvalue 0.392) in geriatric patients suffering from hypertension at the Mauponggo Health Center, Nagekeo, East Nusa Tenggara. Antihypertensive drug interactions did not affect the average blood pressure in geriatric patients in this study. Further research is required to classify the types of antihypertensive drugs that significantly impact blood pressure.
Co-Authors Agustina Setiawati Albertus I. Brilian Aris Widayati Aris Widayati Ariyanti, Ni Kadek Nining Arwinda, Prili Asri, Ni Komang Intan Prima Brilian, Albertus I. Christianus Heru Setiawan Christine Patramurti Co’o, Maria Dolorosa Dewita, Aquina Nino Rama Dhanti Dina Christin Ayuning Putri Distya Pratiwi, Luh Anggi Djaswadi Dasuki Djunaedi, Jeniffer Kalyana Paramita Fenty Fenty Fenty Fenty Fenty Fenty Fenty Fenty Fenty Fenty Fenty Fenty, Fenty Florentinus Dika Octa Riswanto Gollumawo, Serly Sofia D. Gregorius Bhaskara Wikanendra Gregorius Bhaskara Wikanendra Gregorius Bhaskara Wikanendra Handika Immanuel Jago Uko, Maria Anjeline Jannah, Widyatul Leonardo Susanto Utomo Linawati Yunita Lisa Kurnia Sari, Lisa Kurnia Nur, Lisa Febriana Pero, Veronika Giuliany Phebe Hendra Phebe Hendra Phebe Hendra Phebe Hendra, Phebe Pinaryanto, Kartono Pramono, Zita Dhirani Pratiwi, Vera Dwi Priyatni, Nunung Putu Dyana Christasani Rita Suhadi Rohmahtika, Amanda Roni Permana Saputra Sari, Theresia Maria Fioretty Ine Sri Hartati Yuliani Travita, Anggi Silva Tunjung Wibowo Wakitha, Stephanus Satria Wira Wiracana, I Made Yunita Linawati