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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Fitofarmaka Indonesia As-syifaa Jurnal Farmasi Jurnal BALIRESO Window of Health : Jurnal Kesehatan Batoboh : Jurnal Pengabdian Pada Masyarakat Journal of Pharmaceutical and Medicinal Sciences JFIOnline JCPS (Journal of Current Pharmaceutical Sciences) LOYALITAS: Jurnal Pengabdian Kepada Masyarakat Pharmaceutical Reports Journal Microbiology Science JURNAL PENGABDIAN MASYARAKAT YAMASI Jurnal Pengabdian Farmasi dan Sains KOPEMAS MPSJ Jurnal Balireso: Jurnal Pengabdian pada Masyarakat

Masdiana Tahir

Fakultas Farmasi, Universitas Muslim Indonesia, Makassar

Author-ID : 625053

Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Analysis of Artificial Sweeteners, Sodium Cyclamate, in Packaged Beverages and Powders by the Gravimetric Method Pratama, Shinta Indah; Suhaenah, Asriani; Tahir, Masdiana
Pharmaceutical Reports Vol 2, No 2 (2023): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v2i2.267

Most people like instant beverage products because of their practical processing and superior taste and creative packaging, thus attracting consumers to consume them. One of the food additives that is often used in instant beverage products is artificial sweeteners such as sodium cyclamate which has a sweetness level of 3.94 kcal/g or 30 times that of sucrose. This study aims to determine the levels of sodium cyclamate in packaged and powdered drinks circulating on the campus of the Indonesian Muslim University using the gravimetric method. The sampling method used a purposive technique and obtained 6 test samples, qualitative analysis used the precipitation method and obtained all positive samples containing sodium cyclamate. The results of the quantitative analysis obtained the levels of sodium cyclamate for each sample A; B; C; D; E; F as much as 37.07 mg/kg; 30.17 mg/kg; 12.93 mg/kg; 4.31 mg/kg; 340 mg/kg; 258 mg/kg. Thus, these results indicate that all samples do not exceed the levels set by BPOM regulation No. 11 of 2019 concerning food additives, namely 350 mg/kg, so they are safe for consumption.

Antioxidant Activity of Water and Ethyl Acetate Fractions of Qust Al Hindi Root (Saussurea lappa) Using DPPH Inhibition Method Musdalifah, A.; Sukmawati, Sukmawati; Tahir, Masdiana
Pharmaceutical Reports Vol 3, No 2 (2024): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i2.312

Free radicals are molecules that do not have an electron pair in the outer shell, making them highly reactive. Oxidation due to free radicals can be prevented and inhibited by substances, namely antioxidants. Natural antioxidants are obtained from plants or fruits, one of which is Qust al hindi (Saussurea lappa). Qust al hindi is a plant native to India that is used as a traditional medicine. Qust al hindi contains various phytochemical compounds, one of which is flavonoid compounds that function as antioxidants. The purpose of this study was to analyze the antioxidant activity of water and ethyl acetate fractions of qust al hindi plant roots by 1,1-diphenyl-2picrylhydrazyl (DPPH) silencing method using UV-Vis spectrophotometry based on the calculation of IC50 value using GraphPad Prism Application. The results of this study indicate that the water and ethyl acetate fractions of qust al hindi plant roots have antioxidant activity against DPPH free radicals with IC50 values of 203.5 µg/mL; 193.3 µg/mL, respectively, which are included in the very weak and weak antioxidant groups.

In Vitro Anti-Inflammatory Activity of Bajakah Tampala Root (Spatholobus littoralis Hassk.) Maskur, Sri Karina; Tahir, Masdiana; Razak, Rais
Pharmaceutical Reports Vol 4, No 1 (2025): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v4i1.358

Bajakah tampala root (Spatholobus littoralis Hassk.) contains phenolic compounds, flavonoids, tannins, terpenoids and saponins. Flavonoid compounds have pharmacological effects, namely anti-inflammatory. The purpose of this study was to determine the anti-inflammatory activity of ethanol extract of bajakah tampala root by inhibiting protein denaturation in vitro using UV-Vis spectrophotometer and diclofenac sodium as positive control. The extract was prepared by maceration method using 96% ethanol solvent. The results showed that the ethanol extract of bajakah tampala root had a percentage of inhibition of 31.27% at the lowest concentration (10 ppm) and 43.28% at the highest concentration (50 ppm) with an IC50 value of 77.92 µg/mL and the ic50 value of diclofenac sodium is 12.26 µg/mL. The percentage of inhibition that is more than 20% is considered to have inhibitory power in the protein denaturation process. So, it can be concluded that the ethanol extract of bajakah root has potential as an anti-inflammatory.

Determination of Tannin in Ethanol Extract of Bajakah Tampala Root (Spatholobus littoralis Hassk) as an Anticholesterol Saskia, Eka Putri; Tahir, Masdiana; Suhaenah, Asriani
Pharmaceutical Reports Vol 4, No 2 (2025): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v4i2.377

The root of Bajakah Tampala (Spatholobus littoralis Hassk.) is known to contain several bioactive secondary metabolites, including saponins, flavonoids, phenolics, and tannins, which contribute to its broad pharmacological potential. Among these compounds, tannins play an important role in various therapeutic applications such as hemostasis, burn treatment, and the management of diarrhea, dysentery, and tumors. In addition, tannins possess anticholesterol properties by precipitating mucosal proteins on the surface of the small intestine, thereby reducing the absorption of cholesterol and lipids into the bloodstream. This study aimed to determine the tannin content in the ethanol extract of Bajakah Tampala root as part of an investigation into its potential as a natural anticholesterol agent. The extraction process was carried out using the maceration method with 96% ethanol as the solvent to ensure efficient recovery of phenolic compounds. Quantitative analysis of tannin content was performed using the UV-Visible spectrophotometric method at a wavelength of 750 nm, with gallic acid employed as the standard reference compound. The results showed that the tannin concentration in the ethanol extract of Bajakah Tampala root was 91.699 mg GAE/g extract (milligrams of gallic acid equivalent per gram of extract). These findings suggest that Bajakah Tampala root possesses a high tannin content, supporting its potential development as a natural anticholesterol agent and contributing to the growing evidence of its pharmacological benefits in traditional medicine.

Sulfonamide Residue in the Broiler Chicken Circulating in Makassar Fawwaz, Muammar; Razak, Rais; Tahir, Masdiana; Permatasari, Andi; Amula, Andi Tenri; Seniwati, Seniwati
Pharmaceutical Reports Vol 1, No 2 (2022): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

The use of sulfonamide related to drug residual in the product of broiler chicken, like meat and egg. This research aimed to determine the sulfonamides (sulfamerazine, sulfanilamide, and sulfadiazine) on the broiler chicken meat, breast, and egg from the three different slaughterhouses circulating in the City of Makassar. The sample was extracted by acetonitrile and acetone then concentrated. The extract and sulfonamides then analyzed by HPLC method using C18 reverse phased column, UV-Visible detector in the wavelength of 270 nm. The result of study shows that the chromatogram of sample breast and egg has similar retention time with sulfonamides as a standard reference. The breast sample contains sulfamerazine residues, sample B and C contains 0.014 and 0.005 % (w/w), respectively. The egg sample A and D contains sulfadiazine 0.045 and 0.108 % (w/w), respectively. Sample B contains sulfanilamide 0.053 % (w/w). Sample A and B is egg yolk, while sample D is egg whites. Based on the results obtained, this is not suitable for the rules set by JECFA of 0.1 mg/kg (10-5 % w/w) as well as the standard of SNI. It can be concluded that generally broiler chicken breast and egg circulating in the City of Makassar was contaminated by sulfonamide with high concentration.

Determination of Total Phenolic Levels of Ethyl Acetate Fraction of Clove Leaves (Syzygium aromaticum (L) Merr) Arniati, Arniati; Pratama, Mamat; Baits, Muzakkir; Tahir, Masdiana
Pharmaceutical Reports Vol 1, No 2 (2022): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Clove is a spice plant used in the kretek cigarette industry, food, beverage, and medicine. Clove leaves contain chemical compounds, namely saponins, flavonoids, tannins, and essential oils. The exploration of clove leaves has not been maximally carried out. Therefore, this study aims to determine the total phenolic content in the ethyl acetate fraction of clove leaves by using gallic acid as a comparison. Clove leaves were powdered and then macerated by ethanol. The ethanol extract was dissolved in distilled water and it was fractionated with ethyl acetate on a separating funnel. The method used in this assay is the UV-Vis spectrophotometry technique. The qualitative analysis was performed by adding the FeCl3 reagent. The results showed that the ethyl acetate fraction of clove leaves contained a total phenolic compound of 65.52 mg gallic acid equivalent per gram of extract (GAE/g). Thus, the ethyl acetate fraction of clove leaves is feasible to be developed as a source of phenolic compound.

Co-Authors A. Muflihunna A. Muflihunna A. Trihadi Kusuma Afifah Amdar, Andi Aminah Aminah Aminah Aminah Amir, A. Hesti Wulandasari Amula, Andi Tenri Anak Agung Istri Sri Wiadnyani Anda Cahya Heluth arniati, arniati Asriani Suhaenah Azzahra, Resqinah Desi, Nilma Sri Ekawati Ekawati Evatiara, Nur Fitriana Fitriana Hadi, Daryono Hamdhan, Aulia Nurul Insani Harti Widiastuti Hasyim, Amita ISRANANDA, DWI Kaisupy, Siti Sumayya Mamat Pratama, Mamat Maskur, Sri Karina Mochammad Imron Awalludin mondo, zhafira anggraini Muammar Fawwaz Musdalifah, A. Muzakkir Baits, Muzakkir Nasra Nasra Naura Nazhifah Nilla Sukmawati Nurlina Nurwijayanti Permatasari, Andi Pratama, Shinta Indah Putri Nurfauziah Putri, Adinda Rahmawati Rahmawati Rahmawati, Rahmawati Rais Razak, Rais Safitri, Ineks Salahuddin, Muthia Amaliah Sari, Wina Astri Saskia, Eka Putri Seniwati Seniwati, Seniwati Sophi Damayanti St Maryam St Maryam, St St. Maryam, St. Suhaenah, Asriani Suhaenah Sukmawati Sukmawati Sukmawati Sukmawati Sukmawati Syarif, Sukmawati Sumardi, Farah Hikmah Nur Syafrianti Syafrianti Tjahyono Tjahyono Wahdania, Andi Yulinda Rahim Zainal Abidin Zainal Abidin Zainal Abidin

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