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All Journal As-syifaa Jurnal Farmasi Pharmaceutical Reports Jurnal Pengabdian Masyarakat Bhinneka JURNAL PENGABDIAN MASYARAKAT YAMASI Borneo Journal of Pharmacy Celebes Journal of Community Services Indonesian Journal of Jamu MPSJ
Rais Razak, Rais
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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ANALISIS KADAR KAFEIN PADA BIJI KAKAO (THEOBROMA CACAO L.) ASAL KABUPATEN MAMUJU UTARA SULAWESI BARAT DENGAN METODE SPEKTROFOTOMETRI UV-VIS Razak, Rais; Mappacanda, Aco
Jurnal Ilmiah As-Syifaa Vol 3, No 2 (2011): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

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Abstract

Research was conducted to determine the caffeine content in cocoa beans from West Sulawesi North Mamuju with UV-VIS spectrophotometric method at a wavelength of 272 nm. This study used two examples of types of Criollo cocoa and Forastero taken from North Mamuju. Qualitative analysis using mureksid reaction that produces the color purple and brown precipitate region contribute iodide reaction in which in accordance with the reaction on caffeine standard. Analysis of caffeine content was conducted using ultraviolet spectrophotometry at a wavelength of 272 nm and obtained levels - average caffeine for example A  : 4,329mg/0,05g and B: 4,186mg/0,05g.Key words : .Analysis, caffeine, Theobroma cacao L, UV-VIS spectrophotometric.
Wound Healing Ointment Formulation from Essential Oil of Lemongrass (Cymbopogon citratus) Wisdawati, Wisdawati; Razak, Rais; Handayani, Selpida
Jurnal Jamu Indonesia Vol. 10 No. 1 (2025): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v10i1.337

Abstract

Untreated wound may lead to the infection. In some countries, plants are used to cure wound traditionally. Lemongrass (Cymbopogon citratus) has various bioactive compounds, including citronellol, limonene and geraniol that perform some pharmacological activities. In this study, the essential oil of lemongrass was designed into ointment formulation since lemongrass has been reported to have a wound healing effect in mice. The wound healing ointment made from different concentration of the essential oil of Cymbopogon citratus (F1: EOCC 5%, F2: EOCC 10% and F3: EOCC 15%) using a water-removable base and the characteristic as well as the stability (texture, color, smell, homogeneity, and pH) after been stored for 14 days was also evaluated. The result showed that all formulation (F1, F2, and F3) of wound healing formulation revealed good texture, consistency, odor, color, homogeneity and compatible to the skin until 14 days of storage. However, F3 (EOCC 15%) has a strong lemongrass smell compare to the other formulations.
PKM Penyuluhan Rokok dan Bahayanya pada Sekolah Menengah Atas (SMA) di Makassar Abidin, Zainal; Faradiba, Faradiba; Amin, Asni; Fawwaz, Muammar; Olii, Audia Triani; Ririn, Ririn; Razak, Rais; Yulianto, Yuni Zakinah
Jurnal Pengabdian Masyarakat Bhinneka Vol. 3 No. 4 (2025): Bulan Juli
Publisher : Bhinneka Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58266/jpmb.v3i4.198

Abstract

Perilaku merokok di kalangan remaja, khususnya siswa sekolah, menjadi perhatian serius. Data menunjukkan bahwa usia perokok pemula di kelompok usia 13-15 tahun meningkat, bahkan, pada kelompok usia 15-19 tahun dan pada usia 10-14 tahun, hal ini  mengindikasikan bahwa kebiasaan merokok telah menyebar di kalangan siswa sekolah menengah pertama dan atas. Dampak merokok pada kesehatan remaja sangat serius, termasuk risiko kanker, gangguan jantung, diabetes, dan kematian. Faktor yang mendorong remaja merokok antara lain pengaruh teman sebaya, keluarga, iklan, dan kurangnya kesadaran tentang bahaya merokok. Dalam upaya pencegahannya, berbagai program anti-rokok, seperti kampanye di sekolah, media massa, dan kegiatan penyuluhan telah dilakukan. Salah satunya adalah program penyuluhan oleh Fakultas Farmasi Universitas Muslim Indonesia di SMA Negeri 5 Makassar, yang bertujuan meningkatkan pengetahuan siswa tentang bahaya merokok serta mengurangi minat merokok di kalangan remaja. Hasil dari pelaksanaan penyuluhan yang dilakukan memberikan dampak positif terhadap pengetahuan, sikap dan perilaku siswa SMA Negeri 5 Makassar, di mana hasil dari data kuisioner yang dilakukan, sebelum dan sesudah penyuluhan, mengalami peningkatan perubahan pengetahuan, sikap, dan perilaku siswa terhadap rokok, sehingga diharapkan siswa menjadi lebih mengurangi atau bahkan bisa berhenti merokok.
In Vitro Anti-Inflammatory Activity of Bajakah Tampala Root (Spatholobus littoralis Hassk.) Maskur, Sri Karina; Tahir, Masdiana; Razak, Rais
Pharmaceutical Reports Vol 4, No 1 (2025): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v4i1.358

Abstract

Bajakah tampala root (Spatholobus littoralis Hassk.) contains phenolic compounds, flavonoids, tannins, terpenoids and saponins. Flavonoid compounds have pharmacological effects, namely anti-inflammatory. The purpose of this study was to determine the anti-inflammatory activity of ethanol extract of bajakah tampala root by inhibiting protein denaturation in vitro using UV-Vis spectrophotometer and diclofenac sodium as positive control. The extract was prepared by maceration method using 96% ethanol solvent. The results showed that the ethanol extract of bajakah tampala root had a percentage of inhibition of 31.27% at the lowest concentration (10 ppm) and 43.28% at the highest concentration (50 ppm) with an IC50 value of 77.92 µg/mL and the ic50 value of diclofenac sodium is 12.26 µg/mL. The percentage of inhibition that is more than 20% is considered to have inhibitory power in the protein denaturation process. So, it can be concluded that the ethanol extract of bajakah root has potential as an anti-inflammatory.
PENYULUHAN NARKOTIKA DI PESANTREN AN-NAHDHLAH MAKASSAR St. Maryam; Rahmawati; Razak, Rais; Emelda, Andi; Maryam, St; Santi, Irma; Amriati Syarif, Rezky
JURNAL PENGABDIAN MASYARAKAT YAMASI Vol. 4 No. 1 (2025): Jurnal Pengabdian Masyarakat Yamasi
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jpmy.v4i1.379

Abstract

In recent decades, drug abuse has had a very high prevalence. Drug abuse has become a global issue. Its distribution is increasing and supported by the use of advanced technology. The deviation in drug use in Indonesia is already at a very urgent position that needs to be addressed immediately. The ease of drug distribution and use among young people is closely related to the neglect of values, norms, rules, and laws that apply in their social environment. This Community Service aims to provide counseling to third-year students of Madrasah Aliyah Pesantren An-Nahdhlah Makassar about the types, benefits, and dangers of drug abuse in society. The transfer of material was conducted using the method of direct counseling to the PkM partners at the school. The results of the activity included an increase in the partners' knowledge and understanding of the types, benefits, and dangers of drug abuse. Based on the results of the pre and post-test evaluations conducted with the partners, an increase in understanding of the material by 30% was achieved.
ANALISIS KANDUNGAN FORMALIN PADA IKAN KERING DI PASAR TANJONGE SENGKANG KABUPATEN WAJO Abidin, Zainal; Putri, Anggi Dwi; Razak, Rais
Makassar Pharmaceutical Science Journal (MPSJ) Vol 3 No 1 (2025)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v3i1.301

Abstract

Formalin (formaldehyde) is one of the chemical compounds banned by BPOM as a preservative in food additives. This study aims to determine the content of formalin (formaldehyde) in dried fish circulating in the Tanjonge Sengkang market, Wajo Regency. The sampling method used was purposive side and the test method used was qualitative analysis method using KMnO4 reagent, Tollens, Nash, Fehling A and Fehling B and Chromic Acid. The test results using the KMnO4, Tollens, Nash, Fehling A and Fehling B reagents and Chromatophytic Acid of the nine dried fish samples did not contain formalin.
Edukasi Pengolahan Minyak Jelantah Menjadi Sabun Kertas Bernilai Ekonomi Pada Kelompok PKK Tamalanrea Jaya Ahmad, Akstar Roskiana; Kamase, Jeni; Suhaenah, Asriani; Handayani, Virsa; Widiastuti, Harti; Razak, Rais; Abidin, Zainal; Abd. Malik
Celebes Journal of Community Services Vol. 4 No. 2 (2025): Juni - November
Publisher : STIE Amkop Makassar, Indonesia

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Abstract

Tamalanrea Jaya merupakan hasil pemekaran dari Kelurahan Tamalanrea memiliki luas sekitar 31,84 km², dan jumlah penduduk yang diperkirakan pada pertengahan 2023 mencapai 106.262 jiwa. Dengan jumlah penduduk yang tinggi, maka jumlah limbah Rumah Tangga (RT) akan dihasilkan salah satunya adalah minyak jelantah. Permasalahan yang diidentifikasi dalam program ini meliputi minimnya pengetahuan dan keterampilan masyarakat, khususnya ibu-ibu PKK, dalam mengolah limbah RT menjadi produk bermanfaat dan bahkan memiliki nilai ekonomi. Kegiatan ini kami harapkan memberikan kontribusi langsung dalam memperkuat kapasitas masyarakat desa dalam pengolahan limbah RT minyak jelantah dan menciptakan peluang usaha. Kegiatan berlangsung selama tiga bulan dan meliputi beberapa tahap utama, yaitu perencanaan, penyuluhan dan edukasi, pelatihan dan demonstrasi, serta pendampingan dan monitoring. Hasil kegiatan ini berupa sabun kertas dengan banyak keuntungan serperti Praktis dibawa saat bepergian, Mudah larut di air, Ramah lingkungan dan bisa menjadi produk UMKM atau suvenir eco-friendly. Kegiatan pelatihan pembuatan sabun kertas dari minyak jelantah memberikan banyak manfaat bagi ibu-ibu PKK (Pemberdayaan Kesejahteraan Keluarga), baik dari segi lingkungan, ekonomi, keterampilan, hingga kesehatan keluarga. Peningkatan Kesadaran Lingkungan ibu-ibu agar tidak membuang minyak jelantah sembarangan.
Molecular Docking Study of Substituted Benzamide Derivatives as Analgesic Candidates Rahmawati, Rahmawati; Razak, Rais; Fawwaz, Muammar
Borneo Journal of Pharmacy Vol. 8 No. 3 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i3.8715

Abstract

Thiourea derivatives represent a diverse class of compounds exhibiting a range of pharmacological activities, including antitubercular, analgesic, antiviral, and anticancer effects. Of particular interest is N-allyl-N'-(benzoylcarbamothioyl)benzamide, which is hypothesized to possess analgesic properties. A comprehensive in silico molecular docking study was undertaken to evaluate this potential. In silico assays, leveraging computer simulations, are invaluable tools for predicting outcomes, generating hypotheses, and accelerating drug discovery. Molecular docking, a prominent in silico application, facilitates structure-based screening by computationally assessing the binding affinity of compounds to target proteins. This research specifically aimed to predict the analgesic activity of N-allyl-N'-(benzoylcarbamothioyl)benzamide derivatives. To achieve this, various substituents, including methyl, methoxy, tert-butyl, dimethylamino, and halogens, were strategically incorporated at the ortho, meta, and para positions of the benzoylcarbamothioyl ring, generating a library of novel analgesic drug candidates. Compound activity was primarily evaluated using the rerank score. Additionally, ProTox-3.0 and pkCSM were utilized to predict these synthesized compounds' toxicity and physicochemical properties. Initial findings were encouraging, with 18 derivatives of N-allyl-N'-(benzoylcarbamothioyl)benzamide demonstrating enhanced predicted analgesic activity. Among these, six compounds exhibited promising analgesic properties without predicted toxicity. In conclusion, these in silico results suggest that certain N-allyl-N'-(benzoylcarbamothioyl)benzamide derivatives hold significant promise as potential analgesic agents, warranting further validation through subsequent laboratory and in vivo investigations.
Co-Authors Abd. Malik Aco Mappacanda, Aco Ahmad, Akstar Roskiana Amriati Syarif, Rezky Andi Emelda Asni Amin Asriani Suhaenah Audia Triani Olii, Audia Triani Faradiba Faradiba Harti Widiastuti Irma Santi, Irma Kamase, Jeni Masdiana Tahir, Masdiana Maskur, Sri Karina Mochammad Imron Awalludin Muammar Fawwaz Putri, Anggi Dwi Rahmawati Rahmawati, Rahmawati Ririn Ririn Selpida Handayani, Selpida St Maryam, St Virsa Handayani Wisdawati, Wisdawati Yulianto, Yuni Zakinah Zainal Abidin