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All Journal Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Medical and Health Science Journal Jurnal Implementa Husada MAHESA : Malahayati Health Student Journal KESANS : International Journal of Health and Science Jurnal Medis Umum
Nova Primadina
Universitas Muhammadiyah Surabaya
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

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Pengaruh Pemberian Minyak Atsiri Aetoxylon sympetalum terhadap Tingkat Ketahanan Fokus Mahasiswa Tahun Pertama Fakultas Kedokteran Primadina, Nova; sari, Nilam; Levani, Yelvi; Ibrahimiyah, Nur Aisah
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 9 No 01 (2025): Qanun Medika Vol 09 No 01 January 2025
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v9i01.23675

Abstract

First-year medical students tend to experience stress, which can affect how they maintain focus on their work. One alternative treatment that can be done is through relaxation techniques using aromatherapy in the form of essential oils. Crocodile agarwood (Aetoxylon sympetalum) is one of the plants that can provide anxiolytic and antidepressant effects that can be associated with these problems. This study aims to determine the effect of giving Aetoxylon sympetalum essential oil on the level of ability to maintain the focus of first-year students of the medical faculty. This quasi-experiment research method with a nonequivalent control group design was conducted on 34 samples which were divided into control and treatment groups with the same number to see the effect of essential oil on both groups. The research data were analyzed using Spearman's rho test and showed a significance value of 0.004 and a correlation coefficient value of 0.661, meaning that a significant correlation was obtained, the level of correlation between variables was strong and unidirectional. So it can be concluded that the more often inhaling Aetoxylon sympetalum essential oil, the ability to maintain focus will increase.
Literature Review: Pengaruh Pegagan terhadap Penyembuhan Luka Bakar Kusumaningrum, Aliffia Ayu; Primadina, Nova; Laitupa, Afrita Amalia; Triastuti, Nenny
MAHESA : Malahayati Health Student Journal Vol 3, No 7 (2023): Volume 3 Nomor 7 (2023)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (355.059 KB) | DOI: 10.33024/mahesa.v3i7.10728

Abstract

ABSTRACT Burns are injuries caused by the passage of energy from a heat source to the body's tissue under the skin. Each year, 265,000 people die from burns globally, according to WHO (2014). Both traditional and conventional medicine have been used to treat burns, but the price of conventional drugs is relatively high, resulting in inefficient use and side effects such as scar tissue formation, whereas traditional medicine is feared for infection and decreased drug effectiveness due to improper processing. The purpose of this Literature Review is to assess the effect of Centella asiatica on burn healing in general, as well as to investigate the healing quality of burns and the content of Centella asiatica compounds that can cure burns in particular.The search engines Garuda, Google Scholar, ProQuest, Science Direct, and PubMed are used to access and collect data for the study. The search strategy is full-text articles in English and Indonesian from 2012 to 2022. According to comparative research, gotu kola has an anti-inflammatory impact that inhibits inhibition of the proliferative process, and saponin content can speed the creation of connective tissue from collagen type I to type III and avoid scar formation. If there is too much type I collagen, it will burn, asiaticoside will act as an antioxidant, and madecoside will act as an antibacterial.  Asiatica has the capacity to cure second degree A (superficial) burns, especially when the leaves are applied. The extract required is sorted by speed, percentage of healing, and medicinal gel administration (HPMC) 96% ethanol gel extract, 70% ethanol extract, 2% Gotu Kola herb, and 2% ethanol extract 96% ethanolic extract gel of Pegagan herb 6% with 8% HPMC concentration, and 96% herb ethanol extract Gotu Kola 6% in the form of Carbopol 934 gel. Keywords: Centella Asiatica Extract, Burn Healing, Gotu Kola Effect  ABSTRAK Luka bakar adalah kerusakan jaringan bawah kulit tubuh yang diakibatkan oleh pengalihan energi dari suatu sumber panas kepada tubuh. WHO (2014) memperkirakan 265.000 orang meninggal disebabkan luka bakar setiap tahun di dunia. Pengobatan luka bakar sudah banyak beredar  baik secara tradisional maupun obat konvensional namun harganya relatif mahal untuk obat konvensional menyebabkan penggunaan tidak maksimal serta memiliki efek samping seperti pembentukan jaringan parut sementara obat tradisional ditakutkan terjadinya infeksi dan penurunan efektivitas obat akibat pengolahan tidak tepat. Literature Review ini bertujuan secara umum untuk mengetahui pengaruh pegagan terhadap penyembuhan luka bakar dan secara khusus, untuk menganalisa kualitas penyembuhan luka bakar dan melihat kandungan senyawa pegagan yang bisa menyembuhkan luka bakar. Studi menggunakan metode pengambilan dan pengumpulan informasi melalui mesin pencarian Garuda, Google Scholar, Science Direct, dan PubMed. Algoritme pencarian yang digunakan berupa artikel teks lengkap, berbahasa Inggris maupun bahasa Indonesia dari tahun 2012-2022. Berdasarkan artikel-artikel perbandingan diketahui bahwa penelitian pegagan pada luka bakar memiliki efek sebagai penyembuh luka bakar dengan kandungan flavonoid sebagai anti-inflamasi yang mencegah terhambatnya proses proliferasi, kandungan saponin bisa mempercepat pembentukan jaringan ikat dari kolagen tipe I ke tipe III dan mencegah pembentukan bekas luka bakar jika jumlah kolagen tipe I terlalu banyak, asiatikosida sebagai antioksidan, dan madekosida sebagai antibakteri . Tanaman obat Pegagan memiliki efek penyembuhan luka bakar derajat II A (dangkal) terutama penggunaan bagian daunnya, Ekstrak yang dibutuhkan jika diurut dari kecepatan, persentase kesembuhan, pengaplikasiannya jatuh kepada dasar obat gel (HPMC) ekstrak Etanol 70% Herba Pegagan 2%, Gel ekstrak etanol 96% herba Pegagan 5% dengan konsentrasi Carbopol 940 1%, Ekstrak etanol 70% herba Pegagan 3% dengan konsentrasi Gel Carbopol 940 1%, Gel ekstrak etanol 96% herba Pegagan 6% dengan konsentrasi HPMC 8%, Ekstrak Etanol 96% Herba Pegagan 6% dalam bentuk gel Carbopol 934, dan senyawa dalam tanaman obat Pegagan dapat menyembuhkan luka bakar adalah flavonoid, saponin, dan asiatikosida dengan fungsi masing-masingnya Kata Kunci: Ekstrak Pegagan, Penyembuhan Luka Bakar, Efek Pegagan
Peran Hyaluronic Acid untuk Skin Rejuvenation Triastuti, Nenny; Srihartati, Enik; Primadina, Nova; Nabila, Iffah
JurnalMU: Jurnal Medis Umum Vol 1 No 2 (2024): Jurnal Medis Umum
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmu.v2i02.23042

Abstract

Background: As you get older, some cells in the body experience a decrease in the amount of production, including hyaluronic acid. Hyaluronan or hyaluronic acid (HA) is a molecule involved in skin moisture. Skin that loses moisture easily becomes dehydrated and signs of aging appear. Moreover, extrinsic factors such as exposure to UV rays and changing weather conditions also affect the condition of the skin and cause damage to the skin's protective layer. Objective: to determine the role and effectiveness of hyaluronic acid for skin rejuvenation. Methods: Literature review with the title “The Role of Hyaluronic Acid for Skin Rejuvenation” is gain by systematic reviewing of some original research article journal and literature review using search engines such as Google Scholar, PubMed, Scopus, and Elsevier. Results: Hyaluronic Acid (HA) has a role in regulating various biological processes such as skin repair, wound healing, anti-inflammatory, tissue regeneration, and immunomodulation. HA filler injection is an effective therapy for skin rejuvenation because it hydrates, removes fine lines and signs of aging on the skin, and is used to shape facial anatomy according to the patient's wishes. Conclusion : Hyaluronic acid is proven to have effectiveness on skin rejuvenation.
Co-Authors Achmad Basori, Achmad Adinda Rahmawati Afrita Amalia Laitupa Akil, Syafarinah Nurhidayah Alshafiera Azayyana Mawadhani Sukma Annisa Nurida David S Perdanakusuma Dian Novita Andriati Era Catur Prasetya Ibrahimiyah, Nur Aisah Irma Kartikasari Kusumaningrum, Aliffia Ayu Muhammad Tegar Nugraha Nabila, Iffah Nenny Triastuti Nilam Sari Nilam Sari Nur Aisah Ibrahimiyah Nurma Yuliyanasari, Nurma Rianto, Chintya Rosalina Allodya Rony Subagyo Srihartati, Enik Tjatur Prijambodo Yelvi Levani Yohni Wahyu Finansah