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All Journal Cermin Dunia Kedokteran Makara Journal of Health Research The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia
Timoteus Richard, Timoteus
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Health Professions Medicine & Pharmacology Public Health

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Masalah Virus Zika pada Kehamilan Richard, Timoteus; Kristanto, Andi; Adiwinata, Randy; Stephanie, Aurelia; Christianty, Finna; Belinda Phang, Beatrice; Adiwinata, Sheila
Cermin Dunia Kedokteran Vol 43, No 5 (2016): Infeksi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (129.895 KB) | DOI: 10.55175/cdk.v43i5.57

Abstract

Wabah Virus Zika (ZIKV) merebak pada tahun 2015 hingga 2016 terutama di benua Amerika dan mendapat perhatian dunia. ZIKV merupakan penyakit yang ditularkan oleh nyamuk Aedes, umumnya self limiting dan jarang fatal pada dewasa. Perhatian lebih kepada ibu hamil karena potensi janin mikrosefalus. Centers for Disease Control and Prevention (CDC) telah mengeluarkan beberapa rekomendasi diagnosis dan manajemen ZIKV baik pada ibu hamil maupun pada bayi baru lahir. Pencegahan dan diagnosis dini ZIKV menjadi kunci utama penanganan.
A Clinical Profile of Hepatitis A Patients in Jakarta, Indonesia Adiwinata, Randy; Kristanto, Andi; Richard, Timoteus; Edbert, Daniel; Angelina, Frida; Eppy, Eppy; Mauleti, Ifael Y; Lardo, Soroy; Firmansyah, Iman; Bur, Rika; Ahimsa, Titos; Nelwan, Erni J
Makara Journal of Health Research Vol. 21, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: To determine the incidence of hepatitis A infections and the clinical profiles of adult patients admitted to public hospitals in Jakarta, Indonesia. Methods: This was a cross-sectional study that utilised consecutive secondary data from internal medicine wards of seven public hospitals in Jakarta between 2011 and 2013. Eligibility criteria included patients over the age of 18 years and an ICD-10 diagnosis code of B15, acute hepatitis A. Case proportion was reported per 1000 people by dividing incidence per year to total in-ward patients. Clinical profiles were reported descriptively. Laboratory results were compared and categorised into groups of patients aged below and above 25 years old. Results: Data revealed that hospitalisations of patients with hepatitis A had decreased from 2011 to 2013. 289 patients were studied, the majority were young adults (18-25 years old) and their common chief complaints were nausea (36%), fever (24%), and jaundice (21%). Higher bilirubin levels were seen in older patients. There were 13 patients coinfected with hepatitis B, one patient coinfected with hepatitis C, and one patient coinfected with HIV. Conclusions: The proportion of hepatitis A infection amongst adults admitted to public hospitals in Jakarta was low and had decreased during the study period. Most of the patients reported classical clinical manifestations. This study found that the targeted age group may benefit from receiving routine hepatitis A vaccinations.
Tatalaksana Terkini Perlemakan Hati Non Alkoholik Adiwinata, Randy; Kristanto, Andi; Christianty, Finna; Richard, Timoteus; Edbert, Daniel
Jurnal Penyakit Dalam Indonesia Vol. 2, No. 1
Publisher : UI Scholars Hub

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Abstract

Perlemakan Hati Non Alkoholik (Non Alcoholic Fatty Liver Disease/NAFLD) merupakan salah satu penyebab utama dari penyakit hati kronis di negara berkembang. NAFLD dapat berkembang menjadi menjadi penyakit hati yang lebih berat seperti Non Alcoholic Steatohepatis (NASH), sirosis hepatis, dan karsinoma hati. Tatalaksana NAFLD terus berkembang, dan saat ini klinisi dihadapkan dengan berbagai pilihan alternatif baik dari segi nonfarmakoterapi maupun farmakoterapi. Tulisan ini akan membahas berbagai pilihan terapi NAFLD terkini tersebut berdasarkan bukti terbaru.
Association Between Esophagitis Severity and GERDQ Score, Sleep, Life Quality among GERD Patients Waleleng, Andrew; Richard, Timoteus; Rombot, Tisa; Waleleng, Bradley Jimmy; Wenas, Nelly
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 2 (2023): VOLUME 24, NUMBER 2, August, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2422023102-106

Abstract

Background: Gastroesophageal reflux disease (GERD) is characterized with acid reflux, therefore may lead to esophagitis. Acid reflux may cause night symptom of GERD, therefore resulting in decreased sleep and life quality. Gastroesophageal reflux disease questionnaire (GERDQ) is a simple and validated questionnaire for diagnosing GERD. This article aims to investigate association between esophagitis severity and GERDQ score, sleep, life quality among GERD patients at Prof. Dr. R.D. Kandou Hospital.Method: An analytic-cross-sectional study was conducted in gastroenterology clinic of Prof. Dr. R.D. Kandou Hospital between May–June 2021. We included all patients with reflux esophagitis that proven by esophagoduodenoscopy and the severity was graded using Los-Angeles criteria. The GERDQ score was calculated in all patients. The analysis of sleep and life quality was assessed using validated Indonesian version of Pittsburgh-Sleep-Quality-Index (PSQI) and WHO-quality-of-life-BREF (WHOQOLBREF) questionnaire. Independent T-test was used to compare GERDQ, PSQI, WHOQOLBREF score with esophagitis severity degree.Results: Among 30 patients with esophagitis, 70% was male. We found 22 patients with Los-Angeles-grade-A and 8 patients with Los-Angeles-grade-B. The analysis showed no significant different between GERDQ score with esophagitis grade (p = 0.753). There was no association between esophagitis grade with sleep quality (p = 0.125), physical health (p = 0.161), psychological health (p = 0.728), and environmental health (p = 0.133). But we found significant association between esophagitis grade with social relationship life quality (p = 0.028).Conclusion: Patients with higher esophagitis degree had lower social relationship, but not associated with another domain of WHOQOLBREF, sleep quality, and GERDQ score.
Co-Authors Adiwinata, Sheila Adiwinata, Sheila Ahimsa, Titos Andi Kristanto Angelina, Frida Ari Fahrial Syam Belinda Phang, Beatrice Bradley Jimmy Waleleng Daniel Edbert, Daniel Eppy Eppy Erni J Nelwan, Erni J Finna Christianty, Finna Iman Firmansyah Mauleti, Ifael Y Phang, Beatrice Belinda Randy Adiwinata, Randy Rasidi, Josephine Rika Bur Rombot, Tisa Soroy Lardo Stephanie, Aurelia Waleleng, Andrew Wenas, Nelly Willy Brodus Uwan, Willy Brodus