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All Journal Jurnal Riset Kesehatan Majalah Obstetri dan Ginekologi Science and Technology Indonesia Communications in Science and Technology Automotive Experiences Makara Journal of Health Research Jurnal Penyakit Dalam Indonesia
Daniel Edbert, Daniel
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Aerospace Engineering Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Control & Systems Engineering Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Physics

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A Clinical Profile of Hepatitis A Patients in Jakarta, Indonesia Adiwinata, Randy; Kristanto, Andi; Richard, Timoteus; Edbert, Daniel; Angelina, Frida; Eppy, Eppy; Mauleti, Ifael Y; Lardo, Soroy; Firmansyah, Iman; Bur, Rika; Ahimsa, Titos; Nelwan, Erni J
Makara Journal of Health Research Vol. 21, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: To determine the incidence of hepatitis A infections and the clinical profiles of adult patients admitted to public hospitals in Jakarta, Indonesia. Methods: This was a cross-sectional study that utilised consecutive secondary data from internal medicine wards of seven public hospitals in Jakarta between 2011 and 2013. Eligibility criteria included patients over the age of 18 years and an ICD-10 diagnosis code of B15, acute hepatitis A. Case proportion was reported per 1000 people by dividing incidence per year to total in-ward patients. Clinical profiles were reported descriptively. Laboratory results were compared and categorised into groups of patients aged below and above 25 years old. Results: Data revealed that hospitalisations of patients with hepatitis A had decreased from 2011 to 2013. 289 patients were studied, the majority were young adults (18-25 years old) and their common chief complaints were nausea (36%), fever (24%), and jaundice (21%). Higher bilirubin levels were seen in older patients. There were 13 patients coinfected with hepatitis B, one patient coinfected with hepatitis C, and one patient coinfected with HIV. Conclusions: The proportion of hepatitis A infection amongst adults admitted to public hospitals in Jakarta was low and had decreased during the study period. Most of the patients reported classical clinical manifestations. This study found that the targeted age group may benefit from receiving routine hepatitis A vaccinations.
Tatalaksana Terkini Perlemakan Hati Non Alkoholik Adiwinata, Randy; Kristanto, Andi; Christianty, Finna; Richard, Timoteus; Edbert, Daniel
Jurnal Penyakit Dalam Indonesia Vol. 2, No. 1
Publisher : UI Scholars Hub

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Abstract

Perlemakan Hati Non Alkoholik (Non Alcoholic Fatty Liver Disease/NAFLD) merupakan salah satu penyebab utama dari penyakit hati kronis di negara berkembang. NAFLD dapat berkembang menjadi menjadi penyakit hati yang lebih berat seperti Non Alcoholic Steatohepatis (NASH), sirosis hepatis, dan karsinoma hati. Tatalaksana NAFLD terus berkembang, dan saat ini klinisi dihadapkan dengan berbagai pilihan alternatif baik dari segi nonfarmakoterapi maupun farmakoterapi. Tulisan ini akan membahas berbagai pilihan terapi NAFLD terkini tersebut berdasarkan bukti terbaru.
Rotating-Magnetic-Field-Assisted Electrodeposition of Copper for Ambulance Medical Equipment Syamsuir, Syamsuir; Susetyo, Ferry Budhi; Soegijono, Bambang; Yudanto, Sigit Dwi; Basori, Basori; Ajiriyanto, Maman Kartaman; Edbert, Daniel; Situmorang, Evi Ulina Margaretha; Nanto, Dwi; Rosyidan, Cahaya
Automotive Experiences Vol 6 No 2 (2023)
Publisher : Automotive Laboratory of Universitas Muhammadiyah Magelang in collaboration with Association of Indonesian Vocational Educators (AIVE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ae.9067

Abstract

This study examines the influence of the application of a rotating magnetic field in the electrodeposition of copper (Cu). During the electrodeposition, five constant magnets were rotated (500 and 800 rpm) towards the bottom of the sample. To investigate deposition rate, surface morphology, phase, structure, corrosion resistance, and hardness in deposited Cu using a weighing scale, a scanning electron microscope equipped with energy dispersive spectroscopy (SEM-EDS), X-ray diffraction (XRD), potentiodynamic polarization, and hardness tester respectively. Bacterial activity was also evaluated through this research. Morphological surface observations showed that the increase in the rotational speed of the magnets during the electrodeposition process led to a smooth surface. A perfect Cu phase covers Al alloy with no oxide. The potentiodynamic polarization demonstrated by the increase in the rotating led to a shift to the more positive value of the corrosion potential. Moreover, the corrosion current also decreases with the increase in the rotating speed of the magnets. Less crystallite size promoted forming a higher hardness and inhibition zone of the Cu films.
Evaluating Antibacterial And Anti-Biofilm Properties Of Copper And Zinc In Beta Tricalcium Phosphate Against Staphylococcus Epidermidis Aristo, Emanuel Jovan; Situmorang, Evi Margareta; Octavia, Mora; Edbert, Daniel
Jurnal Riset Kesehatan Vol 13, No 2 (2024): NOVEMBER 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v13i2.11701

Abstract

Staphylococcus epidermidis is a common pathogen responsible for peri-implantitis, an infection localized around dental implants. Its virulence is largely attributed to biofilm formation, which enhances resistance to antibiotics and immune defenses. The challenge of treating S. epidermidis is further compounded by its resistance to several antibiotics, including methicillin. This study aimed to evaluate the antibacterial and anti-biofilm properties of a copper-zinc (Cu-Zn) metal alloy and its efficacy when integrated with beta-tricalcium phosphate (β-TCP) as a graft medium against S. epidermidis using in vitro methods. This research employs Staphylococcus epidermidis ATCC 12228. Antibacterial activity was assessed using Direct contact test and viability count via Colony-Forming Unit (CFU) analysis, while biofilm formation was evaluated using the tube adherence method. Increasing copper and zinc concentrations enhanced antibacterial efficacy, with Cu-Zn-β-TCP suspensions showing significantly greater antibacterial activity (p = 0.01) and improved anti-biofilm properties compared to Cu-Zn suspensions without β-TCP. The incorporation of copper and zinc effectively inhibited bacterial growth and biofilm formation of S. epidermidis. Furthermore, the Cu-Zn alloy demonstrated higher efficacy when used in conjunction with β-TCP as a graft medium, suggesting its potential for managing peri-implantitis.
A Small Amount of Sn Addition Effect to Cu-15Zn Alloy on Structure, Microstructure, Hardness, Corrosion Resistance, and Antibacterial Activity Basori, Imam; Sari, Yunita; Prasetya, Dendy Wardhana; Susetyo, Ferry Budhi; Alias, Juliawati; Budi, Setia; Yudanto, Sigit Dwi; Hasbi, Muhammad Yunan; Situmorang, Evi Ulina Margareta; Edbert, Daniel
Science and Technology Indonesia Vol. 10 No. 2 (2025): April
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.2.443-451

Abstract

Cu-15Zn alloy is widely used as a heat exchanger pipe. CuZn alloy was also used for cardiovascular implant applications. Several problems have been found in that alloy, such as less corrosion resistance. Therefore, various Sn (0.2, 0.7, 1, and 2 wt.%) were added to Cu-15Zn alloy in the present research to enhance corrosion resistance. Afterwards, the alloy was homogenized at 800 °C for 2 hours. Several investigations were conducted, such as structure, microstructure, hardness, corrosion resistance, and bacterial activity, using XRD, Optical microscope, Vickers hardness, Potentiostat equipment, and Digital camera. More Sn content leads to an increase in volume and a decrease in hardness. Presenting Sn in the alloy does not influence the phase in the alloy microstructure. The highest Sn content in the alloy promoted a more positive value of the alloy, indicating that the sample is more cathodic, probably due to the protective layer on the surface. A concentration of 1 wt.% Sn exhibits the most effective antibacterial effect probably due to the small crystallite size.
Rotating speed and magnetic pole dependency assisted on copper deposition onto aluminum alloy substrate for bacterial eradication application Basori, Basori; Ruliyanta; Ajiriyanto, Maman Kartaman; Kriswarini, Rosika; Hardiyanti, Heri; Rosyidan, Cahaya; Yudanto, Sigit Dwi; Situmorang, Evi Ulina Margaretha; Edbert, Daniel; Nanto, Dwi; Susetyo, Ferry Budhi
Communications in Science and Technology Vol 10 No 1 (2025)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.10.1.2025.1547

Abstract

Copper (Cu) is widely used in many sectors, such as drinking water piping, heat exchangers, and medical equipment. The present research conducted an electrodeposition of Cu over an aluminum (Al) alloy substrate under the influence of various magnetic poles and rotating speeds. In the present study, a number of investigations, including deposition rate, current efficiency, coating thickness, surface morphology and phase, crystallographic orientation, antibacterial activity, electrochemical behavior, and hardness test were conducted. Increasing the rotation speed promoted to enhanced deposition rate and current efficiency for both magnetic poles influence. An increase in the deposition rate from 12.83 to 13.67 µm/h led to the increasing thickness, a change in surface morphology near the spheroidal, becoming a faceted structure. Presenting and rising in the rotation of a magnetic field led to a reduced surface roughness and crystallite size of Cu film for both magnetic poles influence. The Cu film made without spinning magnetic had a characteristic of highest bacterial inhibition zone around 2.50 ±0.56 cm². The CuRN50 sample had the lowest corrosion rate at around 0.055 mmpy, while the CuRS100 sample had the highest hardness value at approximately 80.72 HV for having the lowest crystallite size. Cu coated onto Al alloy could enhance its properties, such as being antimicrobial, being resistant against corrosion and having the hardness value.
Cu Film Characteristics Synthesized Using Electrodeposition Technique at Various Currents and Under a Rotating Neodymium Magnet Susetyo, Ferry Budhi; Basori; Mansor, Muhd Ridzuan; Ruliyanta; Yudanto, Sigit Dwi; Rosyidan, Cahaya; Situmorang, Evi Ulina Margareta; Edbert, Daniel; Mutiara, Etty; Yulianto, Tri; Agus Jamaludin; Nanto, Dwi
Science and Technology Indonesia Vol. 10 No. 4 (2025): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.4.1156-1168

Abstract

In the present study, Cu films were made over Al alloy using the electrodeposition technique. Electrodeposition conducted at various currents (80, 100, and 120 mA), with and without influence by a rotating magnetic field (100 rpm of rotation). 0.5 M CuSO4 + 20 mL of H2SO4 was used for electrolyte solutions. The sample before and after electrodeposition was weighed using digital scale to calculate deposition rate and current efficiency. All formed Cu films were characterized using X-ray diffraction (XRD), attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR), Scanning electron microscopy equipped with Energy dispersive spectroscopy (SEM-EDS), and Potentiostat apparatus. Furthermore, antibacterial activity using Staphylococcus aureus was also investigated. Increasing the current of electrodeposition leads to an increase in deposition rate and current efficiency for both conditions (with and without rotating magnetic field influence). Based on the XRD and ATR-FTIR investigation, Cu was successfully deposited onto Al surface. Currents used for the electrodeposition process between 80-100 mA would result in a faceted structure, while using 120 mA results near to spheroidal. Shifting to higher currents leads to decreases in grain sizes and presenting a rotating magnetic field also enhances the grain size. Current and rotating magnetic influences are not linearly influencing corrosion potential, corrosion rate and antibacterial activity. The sample made using higher current plus influencing with a rotating magnetic field has less corrosion rate and higher area of inhibition at around 0.808 mmpy and 4.01 cm2.
Evaluating Antibacterial And Anti-Biofilm Properties Of Copper And Zinc In Beta Tricalcium Phosphate Against Staphylococcus Epidermidis Aristo, Emanuel Jovan; Situmorang, Evi Margareta; Octavia, Mora; Edbert, Daniel
Jurnal Riset Kesehatan Vol 13 No 2 (2024): NOVEMBER 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v13i2.11701

Abstract

Staphylococcus epidermidis is a common pathogen responsible for peri-implantitis, an infection localized around dental implants. Its virulence is largely attributed to biofilm formation, which enhances resistance to antibiotics and immune defenses. The challenge of treating S. epidermidis is further compounded by its resistance to several antibiotics, including methicillin. This study aimed to evaluate the antibacterial and anti-biofilm properties of a copper-zinc (Cu-Zn) metal alloy and its efficacy when integrated with beta-tricalcium phosphate (β-TCP) as a graft medium against S. epidermidis using in vitro methods. This research employs Staphylococcus epidermidis ATCC 12228. Antibacterial activity was assessed using Direct contact test and viability count via Colony-Forming Unit (CFU) analysis, while biofilm formation was evaluated using the tube adherence method. Increasing copper and zinc concentrations enhanced antibacterial efficacy, with Cu-Zn-β-TCP suspensions showing significantly greater antibacterial activity (p = 0.01) and improved anti-biofilm properties compared to Cu-Zn suspensions without β-TCP. The incorporation of copper and zinc effectively inhibited bacterial growth and biofilm formation of S. epidermidis. Furthermore, the Cu-Zn alloy demonstrated higher efficacy when used in conjunction with β-TCP as a graft medium, suggesting its potential for managing peri-implantitis.
Comparative analysis of stromal inflammatory cell infiltration and HPV infection status in cervical dysplasia and squamous cell carcinoma using the Klintrup-Mäkinen Scoring method Fahendra, Nicholas Adrian; Edbert, Daniel; Ardianto, Christian; Lilis, Lilis
Majalah Obstetri & Ginekologi Vol. 33 No. 3 (2025): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I32025.188-194

Abstract

HIGHLIGHTS KM score is a reliable method to help determine the diagnosis of cervical dysplasia and squamous cell carcinoma. KM score cannot be used to differentiate infection status in cervical dysplasia and squamous cell carcinoma.   ABSTRACT Objective: Cervical cancer is the second most common malignancy in women, with 604,127 new cases reported globally in 2020. Persistent high-risk human papillomavirus (HPV) infection is the primary cause. This study aimed to evaluate the relationship between stromal inflammatory cell infiltration using the Klintrup-Mäkinen (KM) score and HPV infection status in cervical dysplasia and squamous cell carcinoma (SCC). Materials and Methods: A cross-sectional study was conducted using secondary data from formalin-fixed paraffin-embedded (FFPE) cervical tissue samples diagnosed as dysplasia or SCC at Atma Jaya Catholic University of Indonesia from 2014 to 2022. HPV status was determined using PCR-based assays, while stromal inflammatory cell infiltration was assessed microscopically at 100× magnification and graded according to the KM scoring system by two blinded observers. Statistical analyses, including Chi-square and Spearman’s correlation tests, were performed using STATA/IC 15, with p < 0.05 considered significant. Results: A total of 38 samples were analyzed, comprising 20 (52.63%) cases of dysplasia and 18 (47.37%) cases of SCC. HPV positivity was identified in 70% of dysplasia and 94.44% of SCC cases. KM scores of 2/3, indicating moderate to severe inflammatory infiltration, were significantly more frequent in SCC (77.78%) compared to dysplasia (20%), showing a strong association with pathological diagnosis (p = 0.0019). However, no significant correlation was observed between KM score and HPV status in either lesion type. Conclusion: The KM scoring method provides a reliable and cost-effective approach for assessing stromal inflammatory cell infiltration in cervical lesions, aiding histopathological diagnosis, although it does not predict HPV infection status.
Co-Authors Agus Jamaludin Ahimsa, Titos Alias, Juliawati Andi Kristanto Angelina, Frida Ardianto, Christian Aristo, Emanuel Jovan Bambang Soegijono Basori Basori Basori Cahaya Rosyidan Dwi Nanto, Dwi Eppy Eppy Erni J Nelwan, Erni J Etty Mutiara Evi Ulina Margaretha Situmorang Fahendra, Nicholas Adrian Ferry Budhi Susetyo Finna Christianty, Finna Hasbi, Muhammad Yunan Heri Hardiyanti Imam Basori Iman Firmansyah Lilis, Lilis Maman Kartaman Ajiriyanto Mansor, Muhd Ridzuan Mauleti, Ifael Y Mora Octavia Prasetya, Dendy Wardhana Randy Adiwinata, Randy Rika Bur Rosika Kriswarini Ruliyanta Ruliyanta Setia Budi Soroy Lardo Syamsuir, Syamsuir Timoteus Richard, Timoteus Tri Yulianto Yudanto, Sigit Dwi Yunita Sari