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All Journal Indonesian Journal of Rheumatology Journal of Primary Education eJournal Kedokteran Indonesia Jurnal Penyakit Dalam Indonesia
Ika Prasetya Wijaya
Divisi Kardiologi, Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran Universitas Indonesia/RSUPN Dr. Cipto Mangunkusumo, Jakarta
Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Kardiomiopati pada Penderita Infeksi HIV Sejati, Arif; Wijaya, Ika Prasetya
Jurnal Penyakit Dalam Indonesia Vol. 1, No. 2
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Jantung adalah salah satu organ yang dapat menjadi sumber morbiditas dan mortalitas pada penderita Human Immunodeficiency Virus (HIV)/ Acquired Immunodeificiency Syndrome (AIDS) namun jarang mendapat perhatian khusus. Sebelum era penggunaan highly active antiretroviral therapy (HAART) kelainan jantung khususnya kardiomiopati cukup sering ditemukan. Kardiomiopati didefinisikan sebagai kelompok penyakit heterogen yang dihubungkan dengan disfungsi mekanik dan/atau elektrik yang biasanya (namun tidak selalu) didapatkan hipertrofi atau dilatasi ventrikel yang abnormal dan disebabkan oleh beragam penyebab, kebanyakan genetik. Kardiomiopati pada pasien dengan HIV dapat digolongkan ke dalam kardiomiopati dilatasi yang didapat. Kardiomiopati pada penderita HIV/AIDS disebabkan oleh berbagai faktor: virus HIV, miokarditis, obat-obatan, dan status nutrisi. Pencegahan dan pengobatan dini HIV/AIDS menjadi faktor penting dalam mengurangi morbiditas dan mortalitas akibat kardiomiopati.
Kesintasan Satu Tahun Pasien yang Menjalani Intervensi Koroner Perkutan Primer di Rumah Sakit Dr. Cipto Mangukusumo Hamdan, Muhammad Afriadi; Wijaya, Ika Prasetya; Widhani, Alvina; Yamin, Muhammad
Jurnal Penyakit Dalam Indonesia Vol. 10, No. 3
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Introduction. Primary percutaneous coronary intervention (PPCI) is an angioplasty (with or without a stent) performed immediately on the infarct-related artery without prior administration of fibrinolytics. Although PPCI is the reperfusion therapy of choice in ST-segment Elevation Myocardial Infarction (STEMI) patients, survival in post-PPCI patients still varied and research on its determinant factors still showed inconsistent results. This study aimed to determine the predictors of oneyear survival in patients undergoing PPCI at Dr Cipto Mangunkusumo General Hospital. Methods. This retrospective cohort study evaluated the medical records of patients who underwent PPCI at Dr. Cipto Mangunkusumo General Hospital from January 2014 to December 2019. The data collected included clinical parameters and demographic data from the PPCI registry. Patients’ outcomes were cardiovascular mortality, determined based on medical records or by contacting patients or their families by phone. Survival curves were created using the Kaplan Meier method and significance using the log-rank test. Multivariate analysis was performed using the Cox Proportional Hazard model. Results. A total of 220 patients who underwent PPCI were included in this study. The mortality rate was 11.82% and the one-year survival post-PPCI was 88.2%, with a mean survival of 10.7 (10.2-11.2) months. The highest mortality rate occurred in the first month post of PPCI, then mortality trend decresed in the 2nd month to one year. In multivariate analysis, age >60 years [p<0.001; HR 4.25 (1.93-9.37)], high serum creatinine [P=0.031; HR 2.41 (1.08-5.33)], and Killip score III-IV [p<0.001; HR 4.06 (1.83-9.00)] were significant prognostic factors. Conclusion. The predictors of one years survival patients post of PPCI are age, serum creatinine level, and Killip score.
Faktor-Faktor yang Berhubungan dengan Gejala Depresi pada Pasien Insomnia Usia Lanjut di Rawat Jalan Pratiwi, Amalia Nur; Wahyudi, Edy Rizal; Kusumaningrum, Profitasari; Shatri, Hamzah; Rinaldi, Ikhwan; Gani, Rino Alvani; Wijaya, Ika Prasetya; Susilo, Adityo; Renaldi, Kaka
Jurnal Penyakit Dalam Indonesia
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Introduction. The elderly population is increasing globally, including in Indonesia, where 10.7% of the population in 2020 were elderly. Insomnia is a common health issue among older adults and has been identified as a predictor of depression. This study aims to identify factors associated with depressive symptoms in elderly outpatients with insomnia. Methods. This cross-sectional study was conducted in 2024 on patients aged ≥60 years at the outpatient unit of Cipto Mangunkusumo Hospital (RSCM), Jakarta, Indonesia, using consecutive sampling to select participants. Elderly patients were screened using the Pittsburgh sleep quality index (PSQI), and those with a score >5 (indicating insomnia) were included as study subjects. Data were collected through interviews, covering sociodemographic characteristics, level of loneliness, duration of insomnia, depressive symptoms [Geriatric Depression Scale–15 (GDS-15) items], functional status [Barthel Activities of Daily Living (B-ADL)], cognitive status [Mini-Mental State Examination (MMSE)], nutritional status [Mini Nutritional Assessment (MNA)], and chronic diseases [Cumulative Illness Rating Scale for Geriatrics (CIRSG) score]. Results. The study included 209 elderly subjects with insomnia, with a mean age of 72.88 (SD 6.98) years, and a depression prevalence of 6.7%. Bivariate analysis showed significant associations between dependency (PR 5.24; 95% CI 1.50 – 18.29), malnutrition (PR 11.54; 95% CI 4.77 – 27.92), and chronic disease with a CIRSG score ≥9 (PR 4.15; 95% CI 1.18 – 14.50) and depressive symptoms in elderly patients with insomnia. No significant associations were found between sociodemographic factors, loneliness, duration of insomnia, or cognitive status and depression. Multivariate logistic regression analysis revealed a statistically significant association between malnutrition and depressive symptoms (p < 0.001). Conclusions. There is a significant association between malnutrition and depressive symptoms in elderly outpatients with insomnia. Further cohort studies are recommended to explore the causal relationship between malnutrition and depression in elderly patients with insomnia.
Co-Authors A.A. Ketut Agung Cahyawan W Adeputri Tanesha Idayu Adeputri Tanesha Idayu, Adeputri Tanesha Adityo Susilo, Adityo Adli, Mizanul Aida Lydia Alvina Widhani, Alvina Anwar, Irma Wahyuni Arif Mansjoer Arif Sejati Arif Sejati Cleopas M Rumende, Cleopas M Cleopas Martin Rumende Cleopas Martin Rumende Cosphiadi Irawan Dharmeizar Dharmeizar Dono Antono E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Edward Faisal Edy Rizal Wahyudi Eka Ginanjar Em Yunir Em Yunir, Em Endang Susalit Endang Susalit Fahmi Razi Darkuthni Faisal, Edward Funay, Prijander L B Hamdan, Muhammad Afriadi Ida Zulaeha Ikhwan Rinaldi Jerry Eddya Putra Boer Joko Sutarto Kaka Renaldi Kusumaningrum, Profitasari Laras Budiyani Laras Budiyani, Laras Lugyanti Sukrisman Lusiani Lusiani Lydia D Simatupang Lydia D Simatupang Maruhum B.H. Marbun Muhadi Muhadi, Muhadi Muhammad Ikhsan Muhammad Yamin Murdani Abdullah Murdani Abdullah Pratiwi, Amalia Nur Prijander Lombardia Funay Rino Alvani Gani RR. Ella Evrita Hestiandari Rudi Putranto Rudy Hidayat Sally A Nasution, Sally A Sally Aman Nasution Sally Aman Nasution Sally Aman Nasution, Sally Aman Shirly Elisa Tedjasaputra Siti Setiati Siti Setiati Sukamto Koesnoe Tedjasaputra, Shirly Elisa Wijaya, Indra