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Journal : Bhakta Dental Journal

Pengaruh Obat Calcium Channel Blocker Terhadap Terjadinya Xerostomia Pada Lansia Di Desa Gurah Kabupaten Kediri Pebrianty, Valentina; Prehananto, Herlambang; Kusumastuti, Endah; Soebado, Bagus Musbadiono; Septommy, Catur
Bhakta Dental Journal Vol 1 No 2 (2023): Desember
Publisher : Fakultas Kedokteran Gigi IIK Bhakti Wiyata, Kediri.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/bhaktadent.v1i2.20

Abstract

Background: Hypertension is where systolic blood pressure reaches ≥140 mmHg and diastolic blood pressure ≥90 mmHg in routine examinations. Antihypertensive drugs help patients reduce high blood pressure, but on other hand, these drugs can impact the oral cavity. Amlodipine is one of the calcium-channel blockers (CCB) antihypertensive drugs. Directly and indirectly, antihypertensive drugs can affect salivary flow, causing oral symptoms, including is xerostomia. Xerostomia is a symptom or sign felt by someone with a dry mouth. Objective: To determine the effect of using calcium channel blocker (CCB) drugs on the occurrence of xerostomia in the elderly in Gurah Village, Kediri. Method: This study used an Observational Analytic design, with a cross-sectional design. The data obtained were then analyzed and interpreted to test the hypothesis using the Independent T-test with a nominal and ratio variable data scale. Results: The significant value of the Independent T-test on salivary flow rate was 0.032. (<0.05) which means there is a significant effect Conclusion: There is an effect of using calcium channel blocker drugs on the occurrence of xerostomia in the elderly in Gurah Village, Kediri. Keywords: Hypertension, Calcium Channel Blocker, Xerostomia, Salivary Flow Rate
Peranan Ekstrak Daun Salam Terhadap Angiogenesis Pada Ulkus Traumatikus Prehananto, Herlambang; Pertami, Sawitri Dwi Indah; Sari, Ernita; Fadhilah, Deffira Tifani Fauz
Bhakta Dental Journal Vol 2 No 02 (2024): Desember
Publisher : Fakultas Kedokteran Gigi IIK Bhakti Wiyata, Kediri.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/bhaktadent.v2i02.50

Abstract

Background: Traumatic ulcers are one of the oral cavity problems that have a large prevalence in society. The use of herbal medicine is still being developed, such as the use of bay leaves which aims to accelerate the healing process. The observable wound healing process is the amount of angiogenesis. Objective: To determine the role of bay leaf extract on angiogenesis in traumatic ulcers. Methods: The design of the laboratory experimental study with a total sample used 18 male rats, which were divided into 3 groups: the treatment group was given 5% bay leaf extract gel, the treatment group was given 7.5% bay leaf extract gel, and 1 control group. Each group consisted of 6 research samples. Results: The results of the One Way Anova test showed a significance value (sig) of 0.000, which means that the value was less than 0.05. Conclusion: Bay leaf extract has a role in increasing the amount of angiogenesis in traumatic ulcers