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All Journal JEA17: Jurnal Ekonomi Akuntansi Jurnal Ilmu dan Riset Akuntansi Jurnal ABDINUS : Jurnal Pengabdian Nusantara Jurnal Cahaya Mandalika MAHESA : Malahayati Health Student Journal Jurnal Buana Farma Mejuajua Jurnal Farmasi Indonesia Jurnal Multidisiplin Indonesia Jurnal Riset dan Pengabdian Interdisipliner
Nia Yuniarsih, Nia
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Jurnal Buana Farma

 1 
FORMULASI, UJI ANTIOKSIDAN DAN ANTIBAKTERI SERUM GEL EKSTRAK KULIT PISANG KEPOK (Musa balbisiana) SEBAGAI ANTI- ACNE Yuniarsih, Nia; Abriyani, Ermi; Shadrina, Alliza Nur
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1056

Abstract

One skin problem that never goes away is acne, which is a skin disorder caused by excessive sebum production and can be caused by bacteria such as Propionibacterium acnes. Another factor causing acne is also due to the presence of free radicals. Compounds that can counteract free radicals are antioxidants. This study aims to determine the best formula and storage stability of serum gel of ethanol extract of kepok banana peel (Musa balbisiana) as antioxidant and antibacterial on Propionibacterium acnes bacteria. The study was in vitro with antibacterial activity test using the pitting method and antioxidant activity test using DPPH method. Serum gel preparations were made with three concentrations of kepok banana peel (Musa balbisiana) extract addition, namely formula F1 (5%), F2 (10%), and F3 (15%). Serum gel base was used as negative control and klindamisingel as positive control. This study found that kepok banana peel contains alkaloid, flavonoid, tannin and saponin compounds. Antibacterial activity has an inhibition zone against Propionibacterium acne bacteria at all three concentrations. Serum gel F1 has an inhibition zone of 12.51 ± 0.95, F2 has an inhibition zone of 17.26 ± 0.96, F3 24.08 ± 0.73. Antioxidant activity of serum gel of kepok banana peel (Musa balbisiana) showed IC50 F1 of 95.732 ppm, F2 of 51.368 ppm, F3 of 5.929 ppm. From this study, it can be concluded that serum gel Formula 3 containing 15% ethanol extract of kepok banana peel (Musa balbisiana) is the most effective formula against antibacterial and antioxidant activity.
FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN SHEET MASK BIOSELULOSA MENGANDUNG MINYAK ATSIRI BUNGA KENANGA (Cananga odorata) Farhamzah, Farhamzah; Yuniarsih, Nia; Mursal, Iin Lidia Putama; Anggraeni, Fera
Jurnal Buana Farma Vol. 4 No. 2 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i2.1224

Abstract

The use of antioxidants can be administered orally or topically. Antioxidants are known to be better if given topically in topical dosage forms such as sheet masks, so it is necessary to make masks from natural ingredients that have high antioxidant activity such as Cananga odorata because they contain benzyl benzoate which has anti-free radical properties. This study aims to prove the preparation of biocellulose essence sheet mask containing Cananga odorata has antioxidant activity with concentrations of F1, F2 and F3. Antioxidant testing using the DPPH method. Evaluation of biocellulose sheet mask preparations includes the mask sheet weight test and the mask sheet thickness test. Evaluation of essence preparations includes organoleptic, pH, viscosity, irritation, and hedonic tests. The positive phytochemical screening results contained alkaloids, flavonoids, tannins, and saponins. The results of testing the antioxidant activity of Cananga odorata obtained an IC50 value of 4.027 ppm. Evaluation of essence preparations obtained homogeneous, pH (5.01-6.43), viscosity (400-600 cPs), no irritation occurred in volunteers. Cananga odorata has antioxidant activity in the weak to moderate category, IC50 results for each formula F1 184.212 ppm, F2 150.175 ppm, and F3 72.448 ppm. Based on these results it can be concluded that Cananga odorata can be formulated as an essence with strong antioxidant potential with an IC50 value of 4.027 ppm.
A Fikayuniar, Lia; Yuniarsih, Nia; Abriyani, Ermi; Ayesha, Adinda
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1226

Abstract

Temulawak (Curcuma xanthorrhiza Roxb) is a rhizome plant that has long been used in traditional medicine in Indonesia. The active compounds in temulawak function as antioxidants, which are essential in combating free radicals and preventing cell damage. This study aims to compare the antioxidant activity of ethanol extracts of temulawak obtained through maceration and ultrasonic extraction methods. The research method applied is pre-experimental, with testing conducted in triplicate to ensure result validity. Antioxidant activity was evaluated using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The results show that the ethanol extract of temulawak obtained via maceration method has an IC50 value of 33.379 µg/ml. In contrast, the ultrasonic extraction method showed a lower IC50 value of 9.454 µg/ml, indicating stronger antioxidant activity. Temulawak, as an antioxidant source, has significant potential in the development of herbal products. The comparison of the two extraction methods shows that the ultrasonic method is more effective in enhancing antioxidant activity. This study emphasizes that the extraction method influences the antioxidant activity of temulawak. These results could serve as an important reference for the development of herbal-based products in the future.
FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN CLEANSING BALM EKSTRAK ETANOL BUNGA TELANG (Clitoria ternatea L.) Farhamzah, Farhamzah; Warsito, Ainun Mar’atus Putri; Yuniarsih, Nia
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1227

Abstract

Skin is the outermost layer of the human body that protects the organs inside and skin is the layer that adapts most to the external environment, weather or climate. Facial cleansing is the first step to remove dead skin cells, dirt, sebum and cosmetic residue, which causes acne, redness, irritation and can be made worse by the presence of free radicals. Compounds that are able to ward off free radicals are antioxidants, so this research will make Cleansing Balm with butterfly pea flower extract (Clitoria ternatea L.) as an antioxidant and find out the best formula and storage stability from experimental research by testing antioxidant activity using the DPPH method. The Cleansing Balm preparation was made with three additional concentrations of butterfly pea flower extract (Clitoria ternatea L.), namely F1 (0.1%), F2 (0.2%), and F3 (0.3%). In this research, the results showed that telang flower extract contains alkaloids, flavonoids, quinones, tannins and saponins. The antioxidant activity of Cleansing Balm of butterfly pea flower (Clitoria ternatea L.) shows an IC50 F1 of 95,732 ppm, F2 of 51,368 ppm, F3 of 10,213 ppm. From the research, it can be concluded that Cleansing Balm Formula 3 which contains 0.3% butterfly pea flower extract (Clitoria ternatea L.) is the most effective formula for antioxidant activity
FORMULASI DAN UJI AKTIVITAS ANTIOKSIDAN SEDIAAN FACE MIST FRAKSI DAUN LIDAH MERTUA (Sansevieria trifasciata Prain) Yuniarsih, Nia; farhamzah, Farhamzah; Wulansari, Nur Intan
Jurnal Buana Farma Vol. 5 No. 2 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i2.1475

Abstract

Face mist is a cosmetic that is often used as a skin freshener, serves to refresh facial skin by removing residual oil, as a mild disinfectant, while closing pores again and can have activity as an antioxidant. The Sansevieria trifasciata Prain contains flavonoids, alkaloids and tannins that have the potential to be a source of natural antioxidants. This study aims to examine the potential of n-hexane, ethyl acetate and water fractions of Sansevieria trifasciata Prain as active substances in face mist formulations. This study used the Fractionation and DPPH methods to determine the effectiveness of antioxidant activity of various formulations with F1 (n-hexane fraction); F2 (ethyl acetate fraction) and F3 (water fraction), which were compared with commercial products.. The results showed that F1 and F2 had strong antioxidant activity, while F3 had moderate antioxidant activity. The results of physical evaluation and stability tests using the accelerated stability method (cycling test) showed that the resulting face mist preparation met SNI standards, had good stability and did not cause irritation. From these results, it can be concluded that the n-hexane, ethyl acetate and Sansevieria trifasciata Prain leaf water fractions have the potential to be effective natural antioxidants in the formulation of face mist preparations.
PERAN AMILITE GCK-12H SEBAGAI SURFAKTAN PADA FORMULA SHAMPO: KAJIAN STABILITAS BUSA DAN EFEKTIVITAS PEMBERSIHAN Yuniarsih, Nia; Gunarti, Neni Sri; Mursal, Iin Lidia Putama; Angeline, Tiara Maharani; Abriyani, Ermi; Alkandahri, Maulana Yusuf
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1543

Abstract

Shampoo functions to clean hair and scalp and is generally formulated using Sodium Lauryl Sulfate (SLS) surfactants, which are associated with irritation and unstable foam. Surfactant selection is therefore a critical factor in shampoo formulation, as it influences foam production, softness, hair moisture retention, environmental friendliness, and cleansing effectiveness. Amino acid–based surfactants such as Amilite GCK-12H offer advantages including low irritation potential, good foam stability, and biocompatibility. This study aimed to evaluate the effect of Amilite GCK-12H concentration on cleaning power and foam stability in shampoo formulations. The study was conducted by formulating shampoos and performing accelerated stability testing, including pH, viscosity, organoleptic properties, spreadability, homogeneity, foam stability, and cleaning effectiveness. Four formulations were prepared: F0 without Amilite GCK-12H, F1 containing 5%, F2 containing 10%, and F3 containing 15% Amilite GCK-12H. Organoleptic evaluation showed stable odor and homogeneity in all formulations, although color changes occurred in samples exposed to sunlight. pH testing indicated that all formulations remained within the acceptable range of 5.0–9.0, despite slight decreases under certain storage conditions. Viscosity increased at room temperature but decreased at elevated temperatures. Homogeneity and spreadability tests met standard requirements for shampoo preparations. Formulation F3 demonstrated the best performance in foam stability and cleaning effectiveness, achieving a cleaning efficiency of 62% on day 30. Overall, Amilite GCK-12H proved effective in producing a stable shampoo formulation with improved foam characteristics and cleansing performance. These findings support its potential application as a mild, high-performance surfactant for sustainable cosmetic shampoo development in future industrial formulations globally.
Co-Authors Abriyani, Ermi Aliyani Mardiana, Lina Allahuddin, Allahuddin Amal, Surya Amara, Aisha Nusaiba Amirulloh, Nurhadi Angeline, Tiara Maharani Anggraeni, Fera Anita Permatasari Astuti, Diany Auliya Zulfa, Amanda Ayesha, Adinda Dedy Frianto Devi Setiawati, Devi Dewi, Siska Ratna Fadilla, Reza Akbar Faomasi Gulo, Anasthasya Farhamzah Fathurrohmah, Annis Fikayuniar, Lia Gago, Monica Sylviana Gunarti, Neni Gunarti, Neni Sri Hidayah, Himyatul Khoerunnisa, Rita Maulana Yusuf Alkandahri Maya Arfania Mursal, Iin Lidia Putama Nurunnisa, Ina Pangestu, Anjani Dwi Pratiwi, Tasya Putri Putriana, Amelia Richard Andrew Ruhdiana, Tita Salma Dhaniaty, Siti Shadrina, Alliza Nur Toni. S, Rifqi Maulana Warsito, Ainun Mar’atus Putri Widiyaningsih, Andini Wulandari, Amalia Wulansari, Nur Intan