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Kegiatan Upaya Pencegahan Dini Dan Segera Obati Pada Masyarakat Dengan Pemanfaatan Bahan Alam Sebagai Warisan Budaya Bangsa Noordam, Errol Rakhmad; Nurlaeli, Leli
Jurnal Pengabdian Masyarakat Indonesia Maju Vol 1 No 02 (2020): Jurnal Pengabdian Masyarakat Indonesia Maju Volume 01 Nomer 02 Tahun 2020
Publisher : UIMA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (356.638 KB) | DOI: 10.33221/jpmim.v1i02.659

Abstract

Obesitas merupakan kondisi seseorang yang memiliki angka berat badan diatas angka berat idealnya. Seseorang dengan IMT 30 kg/m² atau lebih umumnya dianggap obesitas, jika IMT25 – 29,9 kg/m² disebut pre obesitas. Untuk orang Asia, BMI diatas 25 kg/m² termasuk obesitas. Masyarakat Indonesia terbiasa mengonsumsi karbohidrat berlebih. Nasi tetap menjadi makanan utama yang memiliki indeks glikemik (IG) yang tinggi sehingga cepat menaikan glukosa dalam darah, sedangkan mie, ubi, dan roti sebagai makanan selingan. Pengabdian Masyarkat PS Sarjana Farmasi ini untuk memberikan informasi dan edukasi kepada masyarakat tentang obesitas dan penangannannya dari seduhan daun tin sebagai anti-obesitas dari bahan alam.
Aktivitas Anti Obesitas Ekstrak Daun Tin (Ficus carica Linn) pada Tikus yang diberi Diet Lemak Tinggi Errol Rakhmad Noordam; Swasono R. Tamat; Syamsudin Abdillah
JURNAL ILMU KEFARMASIAN INDONESIA Vol 17 No 1 (2019): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (423.482 KB) | DOI: 10.35814/jifi.v17i1.700

Abstract

Obesity is a health problem in the community because it can cause a risk of degenerative diseases such as type 2 diabetes mellitus, high blood pressure, heart disease, cancer, and atherosclerosis. Unhealthy lifestyles such as lack of physical activity by exercising, a diet high in carbohydrates and fats, can cause fat deposits in the body, especially in the abdomen. The use of chemical drugs such as Orlistat as a weight loss or to help reduce the risk of regaining lost weight, is less effective because it requires a long consumption time and the presence of side effects. Tin leaf content (Ficus carica Linn) is flavonoids, alkaloids, tannins and steroids, tin leaf extract has IC50 150mg/L antioxidant activity. This study was to determine the anti-obesity activity of tin leaf extract in male Sprague-Dawley rats given a high fat diet. 30 Sprague-Dawley rats were classified into 6 groups. The results obtained, in the group dose of 100 mg / kg obtained an average body weight of 381.8 grams, the test group 200 mg / kg obtained an average body weight of 414.5 grams, in the test group 400 mg / kg obtained 387 grams. The conclusion of this study is that the activity of Tin leaf extract (Ficus carica Linn) can be used as an anti-obesity.
Analisa Prediksi Farmakokinetik Dan Toksisitas Efek Antikanker Payudara Pada Temulawak (Curcuma Zanthorrhiza) Secara In Silico Errol Rakhmad Noordam
Indonesian Journal of Pharmaceutical Education Vol 3, No 3 (2023): September-Desember 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i3.22203

Abstract

Cancer is the main cause of death in developing countries. In Indonesia, breast cancer patients rank the most and are the first cause of death from cancer. Cancer treatment is carried out by surgery or by capturing cancer tissue which is then followed by chemotherapy but this can kill normal cells. Curcumin is the largest content in Temulawak (Curcuma zanthorrhiza). The results of docking using molegro virtual docker show that there is a protein bond with the Curcumin ligand, using a form of validation using various functional evaluations available in Sybil2, so it can be said that the docking value of Curcumin can show its anti-breast cancer effect activity.
BISNIS FARMASI MENJADI PENGUSAHA SKIN CARE SAMBIL KULIAH? BISA! Noordam, Errol Rakhmad; Permadi, Trisna; Sutyono, Bangun; Yudianto, Dian; Wilapangga, Anjas; Thaha, Atifah; Paramita, Gemala; Sundawa, Rachmat Dimas; Syahiruddin, Syahiruddin
TRIDHARMADIMAS: Jurnal Pengabdian Kepada Masyarakat Jayakarta Vol 4 No 2 (2024): PKM-TRIDHARMADIMAS (Desember 2024)
Publisher : Sekolah Tinggi Manajemen Informatika dan Komputer Jayakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52362/tridharmadimas.v4i2.1723

Abstract

Berwirausaha atau menjadi pengusaha adalah proses memulai dan mengelola bisnis. Berwirausaha melibatkan risiko dan pengambilan keputusan bisnis, serta memerlukan perencanaan, inovasi, dan penguasaan berbagai keterampilan bisnis. Bahwa banyak pemuda yang tidak mau berwirausaha padahal sebagai tunas bangsa para pemuda merupakan aset penting bagi kehidupan sosial maupun nasional untuk meningkatkan kualitas hidup masyarakat dan negara. Seharusnya pada saat masa muda harus ditanamkan jiwa kewirausahaan yaitu jiwa berani berusaha mendapatkan ide dan melakukan tindakan yang akan menghasilkan nilai ekonomis tapi itu sangat jarang sekali ditemukan pada pemuda masa kini, hal tersebut bisa disebabkan tidak tahu harus mulai dari mana dan dimana tempat atau wadah untuk mengemukakan ide-ide tersebut. Oleh karena hal – hal tersebut diatas maka Kami berniat mengadakan Seminar Pengabdian Kepada Masyarakat dengan tema “Jadi Pengusaha Skin Care Sambil Kuliah? Bisa”.
Evaluation of Hypochlorite Effectiveness as a Disinfectant Against Aerobic Bacteria Dian Yudianto; Anjas Wilapangga; Errol Rakhmad Noordam; Bangun Sutyono; Trisna Permadi
Natural Sciences Engineering and Technology Journal Vol. 5 No. 1 (2025): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v5i1.66

Abstract

Hypochlorite compounds, including calcium hypochlorite (Ca(OCl)₂) and sodium hypochlorite (NaOCl), are widely recognized for their broad-spectrum antimicrobial properties. This study aimed to evaluate the effectiveness of hypochlorite as a disinfectant against aerobic bacteria, providing insights into its application in infection control and water treatment. The study employed the aerobic bacteria number test, also known as the total plate count method, to enumerate bacterial colonies before and after exposure to varying concentrations of hypochlorite solution. Water samples were collected from different sources, including an emergency room floor, a pharmaceutical installation, and a hospital inpatient room. Serial dilutions of the water samples were prepared and plated on nutrient agar, followed by incubation and colony counting to determine the bacterial load. The percentage reduction in bacterial numbers was calculated for each hypochlorite dose. The results demonstrated a significant reduction in bacterial populations following hypochlorite treatment. A dose of 30 mL/5 L (6 μL/mL) reduced the average number of bacteria by 83.29%, A dose of 60 mL/5 L (12 μL/mL) reduced the average number of bacteria by 98.60%, A dose of 120 mL/5 L (24 μL/mL) reduced the average number of bacteria by 99.84%, A dose of 240 mL/5L (48 μL/mL) reduced the average number of bacteria by 99.98%, A dose of 480 mL/5L (96 μL/mL) reduced the average number of bacteria by 100%. The extent of bacterial reduction was directly proportional to the hypochlorite dose, indicating a clear dose-response relationship. In conclusion, this study confirms the efficacy of hypochlorite as a disinfectant against aerobic bacteria. A hypochlorite dose of 480mL/5L (96 μL/mL) effectively achieved complete bacterial elimination under the tested conditions. The results support its use in various applications, including disinfection of surfaces and water purification.
Quality Parameter Analysis, Antioxidant Activity, and FTIR Profile of Turmeric (Curcuma longa L.) from Medan, Sumba, and Papua Noordam, Errol Rakhmad; Rahmat, Deni; Sandhiutami, Ni Made Dwi; Yuliana, Nancy Dewi
Indonesian Journal of Pharmaceutical Education Vol 5, No 1 (2025): January–April 2025
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v5i1.30494

Abstract

Turmeric (Curcuma longa L.) has long been used as a medicinal plant because it contains bioactive compounds with various health benefits. This research aims to analyze the quality parameters, antioxidant activity and Fourier Transform Infrared (FTIR) spectrum of turmeric originating from Medan, Sumba and Papua. The water content test shows that turmeric extract from Sumba has a water content of 8.55%, better than extracts from Medan and Papua. The highest yield was found in turmeric from Sumba (18.55%). Antioxidant activity testing shows that turmeric extract from Sumba has the strongest antioxidant activity with an IC50 value of 23.74 ppm. FTIR analysis shows the presence of hydroxyl groups (O-H) in the wave number range of 3500-3200 cm⁻¹ and C-H bonds at 3000-2800 cm⁻¹ in all samples. The results of this research show that turmeric from Sumba has better quality than turmeric from Medan and Papua.
Phylogenetic Analysis of Selected Chrysanthemum Species Using matK Gene Sequences: An In Silico Approach Wilapangga, Anjas; Rakhmad Noordam, Errol; Yudianto, Dian
Journal Syifa Sciences and Clinical Research Vol 7, No 3 (2025): Volume 7 Number 3 2025
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v7i3.31516

Abstract

This study evaluated the effectiveness of the matK gene as a molecular marker for identifying and establishing phylogenetic relationships among species within the genus Chrysanthemum. DNA sequence data were retrieved from the NCBI database and analysed using MEGA X software with the UPGMA method and 1000 bootstrap replicates. The resulting phylogenetic tree showed clear species differentiation, with strong clustering between C. indicum and C. × morifolium, and distinct divergence among other species such as C. zawadskii, C. chanetii, and C. lucidum. These findings confirm that matK is a reliable DNA barcoding marker for systematic and taxonomic studies of Chrysanthemum, particularly in addressing the limitations of morphological identification caused by phenotypic variation and hybridisation. However, this study was limited to a single marker, and future research should incorporate additional loci or genomic approaches to obtain a more comprehensive understanding of Chrysanthemum phylogeny.