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Identification of Chemical Constituents in Ethanolic Extract of Hibiscus sabdariffa L. Calyces (Roselle) by FTIR and GC-MS: Preliminary Phytochemical Screening Rohani, Siti; Martha, Fadhil Rizki; Astri, Yesi; Putria, Sinta Julia Liona
Sriwijaya Journal of Medicine Vol. 8 No. 3 (2025): Vol 8, No 3, 2025
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v8i3.360

Abstract

Indonesia is widely recognized for its rich biodiversity, which has long served as a valuable resource for traditional herbal medicine. In recent years, interest in plant-based therapies has grown significantly. One such plant, Hibiscus sabdariffa L., commonly known as Rosella, is valued for its therapeutic properties. These benefits arise from the combined effects of its bioactive compounds, allowing it to address a range of health issues. Research has shown that Rosella contains notable levels of flavonoids, saponins, tannins, and alkaloids—all of which contribute to its antibacterial activity. Techniques such as Fourier-transform infrared (FTIR) spectroscopy and gas chromatography–mass spectrometry (GC-MS) are employed to identify these chemical constituents. FTIR analysis has detected functional groups like amines, fatty acids, aldehydes, carboxylic acids, and aromatic rings. Additionally, GC-MS results have indicated the presence of major compounds belonging to the methyl ester group. Noteworthy identified substances include Hexadecanoic Acid Methyl Ester, Hexadecanoic Acid Ethyl Ester, and Benzenepropanoic Acid, 3,5-Bis(1,1-Dimethylethyl)-4-Hydroxy-, Methyl Ester. A review of existing prior research suggests that these compound groups exhibit significant pharmacological potential, including the usage for antioxidant, anticancer, antibacterial, antidiabetic, and anti-inflammatory effects.
Hubungan Lokasi Ovitrap Atraktan Fermentasi Air Cucian Beras terhadap Keberadaan Telur Aedes Rio, Muhammad; Ramayanti, Indri; Rohani, Siti; Prameswarie, Thia; Saraswati, Nia Ayu
MESINA (Medical Scientific Journal) Vol 6, No 1 (2025): Medical Scientific Journal (MESINA)
Publisher : Universitas Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/msj.v6i1.9334

Abstract

Aedes merupakan vektor utama penyebab Demam Berdarah Dengue (DBD) yang masih menjadi masalah kesehatan di Indonesia, salah satu upaya pengendaliannya dapat dilakukan dengan menggunakan ovitrap dengan penambahan atraktan yaitu fermentasi air cucian beras yang terbukti menghasilkan senyawa ammonia, karbon dioksida dan asam sitrat. Penelitian ini bertujuan untuk mengetahui hubungan penempatan ovitrap dengan keberadaan telur nyamuk Aedes. Desain penelitian ini dengan quasy experiment posttest only. Pengambilan sampel dilakukan dengan teknik purposive sampling, yang didaparkan 6 rumah warga di RT 46, Kelurahan Sukajaya, Kecamatan Sukarami yang merupakan wilayah endemis DBD di Kota Palembang dengan kriteria inklusi yaitu rumah dengan halaman yang cukup luas serta banyak perpohonan. Ovitrap dengan atraktan fermentasi air cucian beras pada penelitian ini diletakkan di luar dan di dalam rumah warga konsentrasi 10%, 30% dan 60% dengan tiga kali ulangan. Analisis data yang digunakan dengan dan Chi-square. Hasil penelitian didapatkan tidak terdapat hubungan antara letak ovitrap dengan keberadaan telur nyamuk Aedes. 
Peningkatan pengetahuan masyarakat terhadap manfaat Bunga Rosella (Hibiscus sabdariffa l.) dalam pencegahan infeksi bakteri Enterobacter aerogenes Rohani, Siti; Trisnawati, Trisnawati; Julia, Sinta; Melianti, Agnes
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 6 No 3 (2025): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V6I3.188

Abstract

Biodiversity is one of Indonesia's riches. One of Indonesia's biodiversity is the Rosella plant (Hibiscus sabdariffa L). Rosella is believed to have benefits because the content of substances contained in it provides a synergistic effect so that it can prevent several health problems. Muara Dua and Pulau Panggung Village in Muara Enim, South Sumatra, is known as one of the areas in Indonesia that produces Rosella flowers widely. The community has a habit of consuming Rosella and this plant has many health benefits because it contains substances in the form of flavonoids, saponins, tannins and alkaloids which have antibacterial activity. The aim of this community service activity is to increase public understanding of the benefits of Rosella plants in preventing infections caused by the bacterium Enterobacter aerogenes. The community service activity involves socialization and education in the form of an offline counseling session. Pre-tests and post-tests were conducted before and after the counseling to assess whether the counseling had any impact. The results, based on 48 respondents with 10 questions, were evaluated using statistical tests from the pre-test and post-test data. The Wilcoxon Signed Rank Test approach was applied, and the negative ranks value indicated a difference in outcomes after the counseling. The asymptotic significance (2-tailed) value was 0.000, and the Z-score value of -5.845 indicates a significant improvement in the respondents' knowledge after the counseling session. The conclusion of this community service activity demonstrates a significant increase in public understanding regarding the benefits of Roselle flowers as a medicinal preparation for combating Enterobacter aerogenes bacterial infections.
Analysis of Risk Factors Influencing the Incidence of Breast Cancer at Muhammadiyah Palembang Hospital Lulu Salsabila; Fadillah Sayuti; Siti Rohani
JURNAL KEDOKTERAN RAFLESIA Vol 12 No 1 (2026): Juni
Publisher : UNIVERSITAS BENGKULU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/juke.v12i1.47984

Abstract

Breast cancer is a malignant disease that originates in the glandular ducts and supporting tissues of the breast and spreads to other regions of the body through a process known as metastasis. Age, hereditary factors, and dietary patterns contribute to an increased risk of developing breast cancer. This study aimed to evaluate the relationship between age, genetic variables, dietary patterns, and the incidence of breast cancer at the surgical outpatient clinic of Muhammadiyah Palembang Hospital. This study employed an observational analytic approach with a cross-sectional design. The population consisted of patients presenting with breast lumps, with a total of 45 respondents selected through purposive sampling. The findings indicated that 68.9% of the respondents were diagnosed with breast cancer, whereas 31.1% were not. Regarding age, 62.2% of the respondents were aged >40 years and had breast cancer, while 37.8% were aged ≤40 years and did not. Furthermore, 51.1% of the respondents had a family history of breast cancer and were affected by the disease, whereas 48.9% were not. In terms of dietary patterns, 37.8% of the respondents were categorized as having a high-risk diet, and 62.2% were classified as non-high risk. Statistical analysis demonstrated a significant association between age and breast cancer incidence (p < 0.001), as well as between hereditary factors and breast cancer incidence (p = 0.019). Conversely, dietary patterns were not significantly associated with the incidence of breast cancer (p = 0.235). In conclusion, age and hereditary factors are significantly associated with the occurrence of breast cancer, whereas dietary patterns show no significant association.