Fajar Shodiq Permata
Faculty Of Veterinary Medicine, Universitas Brawijaya

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SA-5 Case report: Mammary Gland Tubulocarcinoma on Dog Miniature Dachshund at Animal Hospital University of Brawijaya Indonesia Ahmad Fauzi; Albiruni Haryo; Isma Prasthani Hutami Putri; Fajar Shodiq Permata; Nurina Titisari; Anggit Prio Pambudi
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (670.873 KB)

Abstract

In 1 study of 2000 dogs In America, 23% were found to have died due to cancer [1]. Mammary tumors are one of the most common neoplasms of female dogs [2]. This tumor mainly affects middle-aged dogs (9 to 11 years), with an increased incidence that begins at about 6 years old [3]. Sex steroid hormones are thought to have a major role during the early stages of carcinogenesis due to the presence of estrogen and progesterone receptors in higher proportions in most mammary tumours. [3,4]. In addition to hormonal influences, the use of products containing medroxyprogesterone acetate (progestin and estrogen combinations) to prevent estrus in dogs is also associated with an increased incidence of mammary tumors [5]. Mammary tumors can interfere with the physiological appearance and physiological function of the body. This report aims to describe cases of mammary tumors in dogs supported by hematology laboratory examination, blood biochemistry, cytology and histopathology.
Optimization of Tissue Decellularization Method Based on Macroscopic and Microscopic Observation in The Sheep Peripheral Nerves Fajar Shodiq Permata; Rina Susilowati; Rini Dharmastiti; Muhammad Mirandy Pratama Sirat Mirandy Pratama Sirat; Pipin Dwi Kartikasari
Jurnal Sain Veteriner Vol 30, No 2 (2012): DESEMBER
Publisher : Fakultas Kedokteran Hewan Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (13252.092 KB) | DOI: 10.22146/jsv.2606

Abstract

Animal graft tissue  (xenograft) was developed  to replace the limited supply of human graft tissue (allograft). Peripheral nerve graft tissue  is needed to replace  the damage. Swine is the most developed source of tissue donor for the preparation of acellular tissue because a lot of livestocks population and its extracellular matrix components similar to human collagen. Swine xenograft development would be an obstacle in Indonesia because of socio-cultural so that sheep used as swine donor replacement. Sheep cartilage tissue acellular induced less human inflammatory mediators than swine. Xenograft is necessary to decellularizebefore implantation into human that results in only extracellular matrix. However, decellularization process varies depending on the species and methods so that it is needed a preliminary study to get the best decellularization method for sheep peripheral nerve specimens. Five samples of sheep Ischiadicus  nerves were conducted decellularization various processes and one sample of fresh nerve (control). Decellularization methods were 24 hours shaking, tissue soaking and perfusion for both 14 days and 17 days, respectively. Decellularization solution was 0.1% SDS-EDTAin PBS. Post decellularization, samples were observed macroscopically, fixed, HE staining of histopathologic examination for microscopic examination. The data were analyzed descriptively. At the macroscopic observation of post decellularization tissue showed white, and samples of soaking method showed softer consistency than that of shaking and perfusion. Microscopic examination showed that samples were not being completed decellularization at shaking method. There was destruction of collagen fibers of perineurium and endoneurium in 17 days of soaking and perfusion methods, while 14 days soaking and perfusion methods showed that samples were being completed decellularization and both perineurium and endoneurium collagen were still good. Conclusion of this study is that 14 days soaking and perfusion decellularization methods are better than that of 24 hours shaking method and 17 days of soaking and perfusion methods for sheep decellularization peripheral nerve.  
Laporan Kasus: Fibrosarkoma Vagina Pada Anjing Golden Retriever Fauzi Ahmad; Albiruni Haryo; Fajar Shodiq Permata; Nurina Titisari
Jurnal Veteriner Vol 22 No 1 (2021)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (204.254 KB) | DOI: 10.19087/jveteriner.2021.22.1.141

Abstract

A Golden Retriever bitch, 10 years old, came to the Animal Hospital of Brawijaya University, Malang, Indonesia, her conditions was discharge from the vagina, stink smell, polyuria, polydipsia and swelling in the vaginal area that begin to appear one month ago. Physical examination results found her weight 30 kg, scored three for body condition score (scale 1-5), body temperature at 38ºC, pale mucous membrane, and Capillart Reill Time > 2 seconds. Hard mass was palpable in the vaginal area. Based on the anamnesis, physical examination and clinical symptoms, the bitch appeared have some different diagnosis such as pyometra, endometritis, vaginitis, and vaginal tumors. Hematology, radiograph, and histopathological laboratory tests were performed to confirm the diagnosis. Hematologic results showed the bitch suffered from leukocytosis of 41.7 x 103/?L, granulocytosis 36.5 x 103/?L, and hyperchromic microcytic anemia. The results of the radiograph examination showed a radiopaque solid mass in the vagina and uterus. The results of the histopathological examination found there were hyperchromasia nuclei and pleomorphism of fibroblast cell, and formation spindles cell of connective tissue. Based on the results of physical examination, hematological test, radiographic test, and histopathology, the dog was diagnosed with fibrosarcoma in the vagina. The treatment of this case was ovariohysterectomy and removal of the vaginal tumor. Early diagnosis and early treatment largely determine the patient’s prognosis, metastatic vaginal fibrosarcoma tumors showed poor prognosis.
Immunomodulator effect of Robusta Lampung coffee extract (Coffee Canephora Var Robusta) in layer chicken infected with Salmonella enteritidis bacteria Dahliatul Qosimah; Djalal Rosyidi; Lilik Eka Radiati; Indah Amalia Amri; Dodik Prasetyo; Fajar Shodiq Permata; Ma A Guiang Beltran; Aulanni’am Aulanni’am; Agri Kaltaria Annisa
Jurnal Ilmu-Ilmu Peternakan (Indonesian Journal of Animal Science) Vol 30, No 1 (2020): April 2020
Publisher : Faculty of Animal Science, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jiip.2020.030.01.07

Abstract

Salmonellosis that attacks poultry, caused by Salmonella enteritidis is a cause of food borne disease in zoonotic humans. Treatment of this disease uses antibiotics but if used irrationally it can result in the emergence of multi-drug resistant bacteria. At present many treatments use herbs which are considered to reduce the negative effects of antibiotics and are environmentally friendly, one of which is coffee. Green coffee is considered to have many active ingredients such as chlorogenic acid (CGA), alkaloids, tannin, polyphenols and polysaccharides which are useful as antimicrobial, anti-inflammatory and enhances the body's immune system. The study used 60 heads ISA Brown day-old chicks (layer strain) chickens artificially infected with S. enteritidis bacteria with concentration of 108 CFU/ml, consisting of negative controls (healthy chickens, without coffee, positive control (chickens were given), T1, T2 and T3 was given different doses of coffee extract with 500 mg/kg BW, 1000 mg/kg BW and 1500 mg kg BW, respectively. The treatments with coffee extracts were given on days 3-15, then infected with 0.5 ml bacteria on day 16 and 60 chickens were necropsied at day 18 for histopathology. Data on relative levels of CD8 Tc cells were calculated using the flowcytometer test and analyzed quantitatively using the One Way ANOVA with a confidence level of 95% while the jejunum histopathology was observed using a microscopy and analyzed descriptively. Results showed that Robusta coffee extract from Lampung can act as an antibacterial by increasing CD8 + T cells and repairing jejunum histopathology
DISEMINASI MANAJEMEN KESEHATAN DAN REPRODUKSI KAMBING DI DESA MARGOMULYO KECAMATAN TEGINENENG KABUPATEN PESAWARAN: The Dissemination of Health and Reproductive Management of Goats in Margomulyo Village, Tegineneng Subdistrict, Pesawaran Regency. Sirat, Muhammad Mirandy Pratama; Ratna Ermawati; Syahrio Tantalo; Fajar Shodiq Permata
Wahana Peternakan Vol. 8 No. 3 (2024): Wahana Peternakan
Publisher : Faculty of Animal Science, University of Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jwputb.v8i3.1809

Abstract

Desa Margomulyo Kecamatan Tegineneng Kabupaten Pesawaran merupakan salah satu desa yang masyarakatnya beternak kambing sebagai salah satu mata pencaharian utama. Survei pendahuluan menunjukkan minimnya pengetahuan masyarakat terkait manajemen kesehatan dan reproduksi kambing. Tim PKM Unila bertujuan untuk berkontribusi dalam pencapaian SDGs Indonesia dan percepatan penurunan stunting serta memberikan solusi atas permasalahan budidaya kambing di masyarakat dengan diseminasi informasi terkait manajemen kesehatan dan reproduksi kambing melalui penyuluhan, diskusi dan evaluasi melalui kuesioner pre-test dan post-test. Kegiatan diikuti oleh 26 orang peternak kambing di Desa Margomulyo. Kesimpulan kegiatan pengabdian ini yaitu 1) Diseminasi manajemen kesehatan dan reproduksi kambing dapat meningkatkan serapan pengetahuan peserta masing-masing sebesar 52,27% dan 43,08%; 2) Tingkat pengetahuan peternak kambing berdasarkan umur peternak bahwa semakin muda umur peternak maka semakin tinggi asupan serapan pengetahuan terhadap kegiatan pengabdian; dan 3) Tingkat pengetahuan peternak kambing berdasarkan jumlah kepemilikan ternak bahwa semakin sedikit jumlah kepemilikan ternak kambing maka semakin tinggi asupan serapan pengetahuan terhadap kegiatan pengabdian. Kata kunci: Diseminasi, Kambing, Manajemen kesehatan, Manajemen reproduksi, Penyuluhan