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Zazuli, Zulfan
Department Of Pharmacology, Clinical Pharmacy, School Of Pharmacy Institut Teknologi Bandung
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Uji Aktivitas Antistres dan Sedatif Minyak Biji Pala (Myristica fragrans Houtt.) pada Mencit Jantan Galur Swiss Webster Adnyana, I Ketut; Nugrahani, Retta; Suwendar, Suwendar; Zazuli, Zulfan
Acta Pharmaceutica Indonesia Vol 37, No 2 (2012)
Publisher : School of Pharmacy Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (235.347 KB)

Abstract

Telah diteliti efek antistres minyak biji pala (Myristica fragrans Houtt.) yang diberikan secara oral dan aromaterapi secara inhalasi pada mencit jantan Swiss Webster yang diinduksi stres dengan cara imobilisasi. Efek antistres ditentukan berdasarkan jumlah perpindahan mencit dalam kotak transisi terang-gelap dan lama tidur yang diinduksi dengan tiopental. Mencit yang stres ditandai dengan penurunan bobot badan yang bermakna (p<0,05). Minyak biji pala yang diberikan secara oral dengan dosis 16,90 μL/kg bobot badan dan secara aromaterapi dengan konsentrasi 0,4 g/mL dalam minyak kelapa dengan lama inhalasi dua jam memperpanjang waktu tidur (berturut-turut sebesar 208,29±159,63 menit dan 531,00±265,22 menit) secara bermakna (p<0,05) dibadingkan terhadap kontrol (38,00±7,70 menit). Efek antistres minyak biji pala ditandai dengan peningkatan jumlah perpindahan mencit dalam kotak transisi terang-gelap yang berbeda bermakna bermakna dibandingkan terhadap kontrol (9,71±2,98 kali dan 6,71±3,03 kali secara berurutan, p<0,05).Kata kunci: minyak biji pala, Myristica fragrans Houtt, antistres, sedatif.The antistress effect of nutmeg seed oil (Myristica fragrans Houtt.) given orally and as an aromatherapy through inhalation had been evaluated in stressed-male Swiss Webster mice induced by immobilization. The antistress effect was determined based on total number of crossings of mice in light-dark transition box and sleep duration induced by thiopental. Stressed mice were indicated by significant decreased of mice body weight (p<0.05). Nutmeg oil given orally at 16.90 μL/kg body weight and as aromatherapy at concentration of 0.4 g/mL in virgin coconut oil through inhalation for two hours prolonged sleep duration (208.29±159.63 minutes and 531.00±265.22 minutes respectively) significantly (p<0.05) compared to that of control (38.00±7.70 minutes). The nutmeg oil given as aromatherapy by inhalation for two hours significantly increased total number of crossing of mice in light-dark transition box compared to that of control (9.71±2.98 times and 6.71±3.03 times respectively, p<0.05) indicated the antistress effect.Keywords: nutmeg seed oil, Myristica fragrans Houtt, antistress, sedative.
ANALISIS KESESUAIAN DOSIS PADA PASIEN GANGGUAN FUNGSI GINJAL DI SUATU RUMAH SAKIT PENDIDIKAN DI KOTA BANDUNG Zazuli, Zulfan; Hendrayana, Tomi; Pratiwi, Bhekti; Rahayu, Cherry
Acta Pharmaceutica Indonesia Vol 42, No 1 (2017)
Publisher : School of Pharmacy Institut Teknologi Bandung

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Abstract

ABSTRAKPenurunan fungsi ginjal dapat memicu masalah terkait obat akibat terjadinya akumulasi senyawa obat dan timbulnya gangguan patologis lain. Penelitian ini dilakukan untuk mengidentifikasi ketidaksesuaian dosis yang terjadi pada pasien gangguan fungsi ginjal dan menilai sensitivitas pustaka acuan dalam mendeteksi ketidaksesuaian dosis. Penelitian ini dilakukan dengan metode observasi retrospektif pada 266 sampel pasien rawat inap dengan gangguan fungsi ginjal di suatu rumah sakit pendidikan di Kota Bandung pada periode Januari-Maret 2015. Pasien yang diteliti adalah pasien yang menggunakan salah satu atau lebih obat yang diteliti dengan kriteria obat memerlukan penyesuaian dosis, paling banyak digunakan, dan obat untuk komorbid. Kriteria Penggunaan Obat (KPO) untuk 10 obat yang diteliti kemudian dibuat berdasarkan AHFS 2014, DIH 2015 dan Seyffart 2011 dan digunakan sebagai dasar dalam analisis kesesuaian dosis. Dari 176 pasien yang memiliki data mencukupi, terdapat kejadian hari tidak tepat dosis sebesar 54,59% berdasarkan pustaka AHFS-DIH dan 34,96% berdasarkan pustaka Seyffart dari total hari pemberian obat untuk setiap pasien (p<0,05). Pustaka AHFS dan DIH lebih sensitif dalam mendeteksi ketidaksesuain dosis daripada Seyffart. Tingginya persentase ketidaksesuaian dosis menunjukkan diperlukannya pemantauan penggunaan obat terutama dalam aspek pemberian dosis secara terus menerus untuk mengurangi kejadian masalah terkait obat dan memperlambat progresivitas penyakit.Kata kunci: masalah penggunaan obat; gangguan fungsi ginjal; asuhan kefarmasianANALYSIS OF DOSE ADJUSTMENT IN PATIENTS WITH RENAL DYSFUNCTION AT A TEACHING HOSPITAL IN BANDUNGABSTRACTRenal impairment might lead to drug related problems resulted from drug accumulation of drug and other pathological disorders. This study aimed to identify inappropriate dosage on renal impairment patients and investigate sensitivity of literature used for the dosage adjustment. A restrospective observational study was conducted on 266 sample of inpatients with impaired renal function in an academic hospital in January – March 2015 period. The patients studied were patients who used one or more selected drugs with the criteria of drugs requiring dose adjustment, most widely used drugs, and drugs to treat comorbids. The Drug Use Criteria (KPO) for the 10 drugs studied was then made based on AHFS 2014, DIH 2015 and Seyffart 2011 and used as a basis for dose conformity analysis. From 176 patients with sufficient data, there was a 54.59% and 34.96% of the total inpatient days was found to have inappropriate dosing based on AHFS-DIH and Seyffart respectively (p<0.05). The AHFS and DIH libraries are more sensitive in detecting dose nonconformities than Seyffart. The high percentage of dose discrepancy indicates the need for monitoring of drug use especially in the aspect of continuous dosing to reduce the incidence of drug related problems and slow the progression of the diseaseKeywords: drug-related problems; kidney disease; pharmaceutical care
Provision of Patient Medication Counseling Service In A Tertiary-Care Eye Hospital In Bandung: A Gap Analysis of Patient’s Need, Standard and Service Provider Resources Hendrayana, Tomi; Zazuli, Zulfan; Fadhila, Genialita; Cahyono, Nur Sidik
Indonesian Journal of Pharmacy Vol 28 No 4, 2017
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1055.414 KB) | DOI: 10.14499/indonesianjpharm28iss4pp232

Abstract

Many studies showed that counseling can improve patient adherence and reduce medication-related problems leading to reach an optimal outcome therapy. The aims of this study were to identify patient’s need, healthcare professional’s support, pharmacist’s readiness and step to be taken to meet standard for implementing patient medication counseling service. Questionnaires has been given to hospitalized-patient to identify the patient’s need and to healthcare professionals in recognizing their supports, followed by survey of pharmacist’s readiness. Gap analysis was then carried out to identify the additional resources to be provided for conducting the service. About 103 patients were enrolled and eager for drug counseling to be implemented with pharmacist as healthcare counselor. Approximately 46 nurses and 25 active-medical-doctors were participated and giving their support for pharmacist to provide the service; and pharmacists are ready to conduct patient medication counseling with minor adjustment. Gap analysis concluded that additional resources should be furnished, e.g. information module consist of standard information needed by the patient, standard operational procedure, and updated literatures. Due to lack of pharmacist, counseling service only be delivered to patient who has a complex antibiotic regimen therapy. Our data showed that patient medication counseling service in this center could be quickly implemented.
Evaluasi Penggunaan Antibiotik pada Pasien Bedah di Suatu Rumah Sakit Swasta di Bandung Zulfan Zazuli; Elin Y. Sukandar; Ida Lisni
Indonesian Journal of Clinical Pharmacy Vol 4, No 2 (2015)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.144 KB) | DOI: 10.15416/ijcp.2015.4.2.87

Abstract

Pemberian antibiotik prabedah dan pascabedah telah digunakan secara luas untuk menghindari dan menangani infeksi pada daerah pembedahan. Penggunaan antibiotik harus dievaluasi melalui program evaluasi penggunaan obat (EPO) untuk  menjamin penggunaan obat yang rasional. EPO antibiotik ini dilakukan berdasarkan pada kriteria penggunaan obat yang telah ditetapkan menggunakan studi data retrospektif dari bulan September sampai dengan November tahun 2009 untuk seluruh pasien bedah di salah satu rumah sakit swasta di Bandung. Telah dilakukan pemberian antibiotik sebanyak 1290 dosis yang terdiri atas pemberian antibiotik prabedah sebanyak 94 dosis dan pemberian antibiotik pascabedah sebanyak 1196 dosis. Telah terjadi ketidaktepatan penggunaan antibiotik yang terdiri atas ketidaktepatan indikasi sebesar 0,39%, dosis berlebih dan dosis kurang pada pemberian antibiotik pascabedah berturut-turut sebesar 2,26% dan 0,50%, ketidaktepatan waktu pemberian antibiotik prabedah sebesar 22,34%, interaksi obat sebesar 1,78% yang terdiri atas 0,46% interaksi farmakokinetik dan 1,31% interaksi farmakodinamik, serta duplikasi antibiotik sebesar 0,46%. Dapat disimpulkan bahwa terjadi beberapa ketidaktepatan penggunaan antibiotik. Ketidaktepatan yang paling besar terjadi pada ketidaktepatan waktu pemberian antibiotik prabedah. Dibutuhkan peran serta apoteker rumah sakit sebagai bagian dari upaya peningkatan ketepatan penggunaan antibiotik pada pasien bedah.Kata kunci: Antibiotik, evaluasi penggunaan obat, pembedahan, studi retrospektif Antibiotic Use Evaluation in Surgery Patients at a Private Hospital in BandungAntibiotic administrations in presurgery and postsurgery are widely used to avoid and to treat surgical site infections. In order to ensure the rational use of this drug, the use of antibiotic should be evaluated through drug use evaluation (DUE) programme. In this research, the DUE programme had been carried out based on predetermined criteria using restrospective data study from September until November 2009 to all surgery patients at a private hospital in Bandung. This research showed that 1290 doses antibiotic had been given to patients to treat surgical site infections, which were consist of 94 doses presurgery antibiotic and 1196 doses postsurgery antibiotics. This study showed the presence of inappropriate antibiotic uses that consists of 0.39% inappropriate indications; 2.26% overdoses and 0.50% subtherapy doses; 22.34% inappopriate administration timings of presurgery antibiotic; 1.78% drug interactions which 0.46% are pharmacokinetic drug interactions and 1.31% are pharmacodynamic drug interactions; and 0.46% antibiotic duplications. It can be concluded that there is some inappropriate use of antibiotics. The greatest inappropriateness is inappopriate administration timings of presurgery antibiotic. The role of the hospital pharmacist is needed as part of efforts to increse the appropriateness use of antibiotics in surgical patients.Key words: Antibiotic, drug use evaluation, restrospective study, surgery
Permasalahan Terkait Obat (Drug Related Problems/DRPs) pada Penatalaksanaan Penyakit Ginjal Kronis dengan Penyulit Penyakit Arteri Koroner Winda H. Furqani; Zulfan Zazuli; Nabilah Nadhif; Siti Saidah; Rizky Abdulah; Keri Lestari
Indonesian Journal of Clinical Pharmacy Vol 4, No 2 (2015)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2487.813 KB) | DOI: 10.15416/ijcp.2015.4.2.141

Abstract

Masalah terkait obat (DRPs) didefinisikan sebagai setiap kondisi dalam penatalaksanaan terapi pasien yang menyebabkan atau berpotensi menyebabkan tidak tercapainya hasil terapi yang optimal. Penelitian ini dilakukan di salah satu rumah sakit di Kota Cimahi pada bulan Mei 2014. Pada penelitian ini dilakukan identifikasi DRPs pada pasien wanita berusia 59 tahun yang didiagnosis penyakit ginjal kronis dengan penyulit penyakit arteri koroner dan gangren di tangan kiri (jari ke-3). Pasien diketahui mempunyai riwayat diabetes melitus sejak dua hingga tiga tahun yang lalu. Melalui kajian DRPs ditemukan permasalahan terkait obat, yaitu adanya terapi obat yang tidak diperlukan (pemberian kalsium polistiren sulfonat), ketidaktepatan pemilihan antibiotik, Ketidaktepatan dosis (pemberian amoksisilin dan kaptopril), dan risiko interaksi obat-obat merugikan (interaksi kaptopril–furosemid, kaptopril–isosorbid dinitrat, dan kaptopril–natrium bikarbonat). Pasien penyakit ginjal kronis dengan penyulit penyakit arteri koroner menerima terapi obat yang kompleks sehingga meningkatkan risiko terjadinya DRPs. Keterlibatan apoteker klinis di rumah sakit dalam penatalaksanaan penyakit yang kompleks diperlukan untuk mengoptimalkan terapi, meminimalisir risiko DRPs, dan meningkatkan kualitas hidup pasien.Kata kunci: Drug related problems, penyakit ginjal kronis, penyakit arteri koronerDrug Related Problems in the Management of Chronic Kidney Disease with Coronary Artery DiseaseDrug related problems were defined as conditions on patient’s therapy management that caused, or potentially caused unsuccessful therapy. This study was conducted at a hospital in Cimahi City in May 2014. In this study, DRPs were identified on a 59 years old woman who was diagnosed with chronic kidney disease and coronary artery disease with gangrene on the left hand (the third finger). The patient also had a diabetes mellitus for two until three years ago. Drug related problems (DRPs) were found in this patient. Unnecessary drug therapy (administration of calsium polystirene sulfonate), inappropriate choosen antibiotic, inappropriate dosing (administration of amoxicillin and captopril), and risks drug interactions (captopril–furosemide, captopril–isosorbide dinitrate, and captopril–sodium bicarbonate). Patients with chronic kidney disease and coronary artery disease received complex drug therapy. These condition lead to higer risk of DRPs. The involvement of clinical pharmacist in interdisciplinary team for management of complex diseases was needed to monitor drug therapy to optimizing the therapy, minimalizing the risk of DRPs, and improving patient’s quality of life.Key words: Chronic kidney disease, coronary artery disease, drug related problems
Uji Aktivitas Antistres dan Sedatif Minyak Biji Pala (Myristica fragrans Houtt.) pada Mencit Jantan Galur Swiss Webster I Ketut Adnyana; Retta Nugrahani; Suwendar Suwendar; Zulfan Zazuli
Acta Pharmaceutica Indonesia Vol. 37 No. 2 (2012)
Publisher : School of Pharmacy Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Telah diteliti efek antistres minyak biji pala (Myristica fragrans Houtt.) yang diberikan secara oral dan aromaterapi secara inhalasi pada mencit jantan Swiss Webster yang diinduksi stres dengan cara imobilisasi. Efek antistres ditentukan berdasarkan jumlah perpindahan mencit dalam kotak transisi terang-gelap dan lama tidur yang diinduksi dengan tiopental. Mencit yang stres ditandai dengan penurunan bobot badan yang bermakna (p<0,05). Minyak biji pala yang diberikan secara oral dengan dosis 16,90 μL/kg bobot badan dan secara aromaterapi dengan konsentrasi 0,4 g/mL dalam minyak kelapa dengan lama inhalasi dua jam memperpanjang waktu tidur (berturut-turut sebesar 208,29±159,63 menit dan 531,00±265,22 menit) secara bermakna (p<0,05) dibadingkan terhadap kontrol (38,00±7,70 menit). Efek antistres minyak biji pala ditandai dengan peningkatan jumlah perpindahan mencit dalam kotak transisi terang-gelap yang berbeda bermakna bermakna dibandingkan terhadap kontrol (9,71±2,98 kali dan 6,71±3,03 kali secara berurutan, p<0,05).Kata kunci: minyak biji pala, Myristica fragrans Houtt, antistres, sedatif.The antistress effect of nutmeg seed oil (Myristica fragrans Houtt.) given orally and as an aromatherapy through inhalation had been evaluated in stressed-male Swiss Webster mice induced by immobilization. The antistress effect was determined based on total number of crossings of mice in light-dark transition box and sleep duration induced by thiopental. Stressed mice were indicated by significant decreased of mice body weight (p<0.05). Nutmeg oil given orally at 16.90 μL/kg body weight and as aromatherapy at concentration of 0.4 g/mL in virgin coconut oil through inhalation for two hours prolonged sleep duration (208.29±159.63 minutes and 531.00±265.22 minutes respectively) significantly (p<0.05) compared to that of control (38.00±7.70 minutes). The nutmeg oil given as aromatherapy by inhalation for two hours significantly increased total number of crossing of mice in light-dark transition box compared to that of control (9.71±2.98 times and 6.71±3.03 times respectively, p<0.05) indicated the antistress effect.Keywords: nutmeg seed oil, Myristica fragrans Houtt, antistress, sedative.
ANALISIS KESESUAIAN DOSIS PADA PASIEN GANGGUAN FUNGSI GINJAL DI SUATU RUMAH SAKIT PENDIDIKAN DI KOTA BANDUNG Zulfan Zazuli; Tomi Hendrayana; Bhekti Pratiwi; Cherry Rahayu
Acta Pharmaceutica Indonesia Vol. 42 No. 1 (2017)
Publisher : School of Pharmacy Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRAKPenurunan fungsi ginjal dapat memicu masalah terkait obat akibat terjadinya akumulasi senyawa obat dan timbulnya gangguan patologis lain. Penelitian ini dilakukan untuk mengidentifikasi ketidaksesuaian dosis yang terjadi pada pasien gangguan fungsi ginjal dan menilai sensitivitas pustaka acuan dalam mendeteksi ketidaksesuaian dosis. Penelitian ini dilakukan dengan metode observasi retrospektif pada 266 sampel pasien rawat inap dengan gangguan fungsi ginjal di suatu rumah sakit pendidikan di Kota Bandung pada periode Januari-Maret 2015. Pasien yang diteliti adalah pasien yang menggunakan salah satu atau lebih obat yang diteliti dengan kriteria obat memerlukan penyesuaian dosis, paling banyak digunakan, dan obat untuk komorbid. Kriteria Penggunaan Obat (KPO) untuk 10 obat yang diteliti kemudian dibuat berdasarkan AHFS 2014, DIH 2015 dan Seyffart 2011 dan digunakan sebagai dasar dalam analisis kesesuaian dosis. Dari 176 pasien yang memiliki data mencukupi, terdapat kejadian hari tidak tepat dosis sebesar 54,59% berdasarkan pustaka AHFS-DIH dan 34,96% berdasarkan pustaka Seyffart dari total hari pemberian obat untuk setiap pasien (p<0,05). Pustaka AHFS dan DIH lebih sensitif dalam mendeteksi ketidaksesuain dosis daripada Seyffart. Tingginya persentase ketidaksesuaian dosis menunjukkan diperlukannya pemantauan penggunaan obat terutama dalam aspek pemberian dosis secara terus menerus untuk mengurangi kejadian masalah terkait obat dan memperlambat progresivitas penyakit.Kata kunci: masalah penggunaan obat; gangguan fungsi ginjal; asuhan kefarmasianANALYSIS OF DOSE ADJUSTMENT IN PATIENTS WITH RENAL DYSFUNCTION AT A TEACHING HOSPITAL IN BANDUNGABSTRACTRenal impairment might lead to drug related problems resulted from drug accumulation of drug and other pathological disorders. This study aimed to identify inappropriate dosage on renal impairment patients and investigate sensitivity of literature used for the dosage adjustment. A restrospective observational study was conducted on 266 sample of inpatients with impaired renal function in an academic hospital in January "“ March 2015 period. The patients studied were patients who used one or more selected drugs with the criteria of drugs requiring dose adjustment, most widely used drugs, and drugs to treat comorbids. The Drug Use Criteria (KPO) for the 10 drugs studied was then made based on AHFS 2014, DIH 2015 and Seyffart 2011 and used as a basis for dose conformity analysis. From 176 patients with sufficient data, there was a 54.59% and 34.96% of the total inpatient days was found to have inappropriate dosing based on AHFS-DIH and Seyffart respectively (p<0.05). The AHFS and DIH libraries are more sensitive in detecting dose nonconformities than Seyffart. The high percentage of dose discrepancy indicates the need for monitoring of drug use especially in the aspect of continuous dosing to reduce the incidence of drug related problems and slow the progression of the diseaseKeywords: drug-related problems; kidney disease; pharmaceutical care
IDENTIFICATION OF DRUG-RELATED PROBLEMS ON BETA LACTAM ANTIBIOTICS USED FOR PEDIATRIC AT A SECONDARY-CARE HOSPITAL IN CIMAHI Zulfan Zazuli; Tomi Hendrayana; Siti Farah Rahmawati; Shalvierra Polyta Fitriah
Acta Pharmaceutica Indonesia Vol. 42 No. 2 (2017)
Publisher : School of Pharmacy Institut Teknologi Bandung

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Abstract

WHO estimated that >50% of medicines are used inappropriately. One that posess highest risk due to inappropriate use is beta-lactam antibiotic, espescially in pediatric patient since the organ function in pediatric patient has not fully developed as in adult yet. This cross-sectional study was performed to identify drug-related problems (DRPs) occurred during beta-lactam therapy in pediatric hospitalized in a secondary-care hospital in Cimahi. A predetermined medication-use criteria based on the current literatures was created as an assessment standard tools. Furthermore, identification of DRPs based on PCNE v6.2 classification was carried out concurrently (January-March 2015) to 351 patients. As many as 458 DRPs were found including 22 cases inappropriate drugs (category C1.1), 127 cases no indication for drug (C1.2), 42 cases inappropriate combination of drugs, or drugs and food (C1.4), 1 case of too many drugs prescibed for indication (C1.6), 137 cases drug dose too low (C3.1), 89 cases drug dose too high (C3.2), 39 cases duration of treatment too short (C4.1), and 1 case of duration of treatment too long (C4.2). The potential DRPs was estimated to be occured for approximately 1-2 DRPs per patient.Keywords: drug-related problems; beta-lactam antibiotic; pediatric; pharmaceutical care
Evaluating Inhaler Use Technique among Asthma and COPD Patients at a Primary Health Care Unit: A Pilot Study in Selangor Malaysia Zulfan Zazuli; Kogilavani Ramasamy; I Ketut Adnyana
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 8, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.33829

Abstract

Inhaler is the most preferable device to deliver medication in order to treat asthma and Chronic Obstructive Pulmonary Disease (COPD). Incorrect usage of inhaler influences the clinical effectiveness of the delivered drug. A pilot study was conducted to determine the appropriateness of inhaler handling technique among asthma and COPD patients. As many as 92 subjects whom diagnosed with asthma and COPD, aged between 18 to 64 years old were observed in this cross-sectional study. Consenting subjects on inhaler, who attended medical out patients clinic at a primary health care unit in Selangor, Malaysia were asked to demonstrate on how they use the inhaler while an inhaler administration checklist were used to assess each patients inhaler technique. Data was analysed using descriptive statistical methods. Of total 92 patients, a total of 155 devices were used. Only 4 out of 92 patients correctly handles the device (4.3%). In average, a patient made approximately >4 mistakes during pMDI inhalation and >2 mistakes during DPI inhalation. The most common mistake found among pMDI, Turbuhaler and Accuhaler users were unable to hold the breath for approximately 5 seconds in which comprise of ≥80% patients. In conclusion, majority of asthma and COPD patients use their inhaler inaccurately. Patients prescribed by inhalation medications should have routine assessment of their inhaler technique at every visit and corrected if found to be poor.
Impact of education on anemia in pregnant women attending Bandung community health centers: knowledge, therapy adherence, hemoglobin, and iron intake Zazuli, Zulfan; Furqani, Winda Haniva; Putri, Suci Utami Ayungga
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 2 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i2.1559

Abstract

Anemia in pregnant women poses risks to maternal and infant health. Iron supplementation therapy (IST) adherence and adequate dietary iron intake are crucial for maintaining normal hemoglobin (Hb) levels. This study investigates the impact of education on iron deficiency anemia (IDA) knowledge, IST adherence, iron intake, and Hb levels in pregnant women. A pre-post test study was conducted at Padasuka and Pagarsih Community Health Centers in Bandung. Questionnaires measuring IDA knowledge, Brief Medication Questionnaire (BMQ) for IST adherence, and Food Frequency Questionnaire (FFQ) for iron intake were utilized. This study included a total of 88 pregnant women. The majority of the participants were aged 26-35 years (55.7%), had normal BMI values (45.4%), and exhibited normal blood pressure (60.2%). Additionally, 89.8% had no history of anemia, 90.9% had no other medical history, 92% reported having a good appetite, and 97.7% did not smoke. Education significantly improved IDA knowledge (p = 0.011), IST adherence (p = 0.006), iron intake (p = 0.001), and Hb levels (p = 0.011). Strong positive correlations were found between knowledge of IDA in pregnant women and adherence to IST (r = 0.957; p<0.001), knowledge and Fe intake (r = 0.972; p<0.001), knowledge and Hb levels (r = 0.988; p<0.001), adherence to IST and Fe intake (r = 0.933; p<0.001), adherence to IST and Hb levels (r = 0.948; p<0.001), as well as Fe intake and Hb levels (r = 0.978; p<0.001). Enhanced knowledge, IST adherence, and iron intake may mitigate anemia risks in pregnant women.
Co-Authors Akromy, Muhammad Zidan Fikri Anjasmara, Aulia Putri Aryantha, Hasna Firdaus Basuki , Bhekti Pratiwi Cahyono, Nur Sidik Cherry Rahayu Elin Y. Sukandar Fadhila, Genialita Faustincia, Ivena Furqani, Winda Haniva Hani Sri Fitriani Hendrayana, Tomi I Ketut Adnyana I Ketut Adnyana Ida Lisni Keri Lestari Kogilavani Ramasamy Kusnandar Anggadiredja LIA AMALIA Nabilah Nadhif Nugrahani, Retta Pratiwi Wikaningtyas Pratiwi, Bhekti Putri, Suci Utami Ayungga Rahayu, Cherry Rahmawati, Siti Farah Ramasamy, Kogilavani Retta Nugrahani Reyaan, Irianti Bahana Maulida Rizky Abdulah Rukmawati, Iis Shalvierra Polyta Fitriah Siti Saidah Suwendar Suwendar Tomi Hendrayana Winda H. Furqani Wisasani, Amiiratu Muthiia