Setyabudi Setyabudi
Dental Medicine Faculty, Airlangga University, Surabaya

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The Difference of Irrigant Solution between Red Pine Extract (Pinus densiflora) and Green Pine Extract (Pinus merkusii) Against Cleanliness of Root Canal Walls Dian Agustin Wahjuningrum; Setyabudi Setyabudi; Sukaton Sukaton; Yuline Krishartini
Conservative Dentistry Journal Vol. 10 No. 2 (2020): July-December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v10i2.2020.62-65

Abstract

Background: Smear layer is an accumulation of organic material, debris, and inorganic material in root canal wall. Irrigant solution must be able to eliminate organic and inorganic materials. Herbal extract such as pine contain saponins that can dissolve organic and inorganic materials. Korea is a country that has used pine in this case red pine as an antibacterial medicament. In Indonesia, there are also green pine species. Purpose: To explain the differences in cleanliness of the root canals after irrigation using extracts of red pine (Pinus densiflora) and green pine (Pinus merkusii). Methods: This study used twenty-seven mandibular premolar teeth which were divided into 3 groups each group consisted of 9 premolar teeth. All samples were prepared using ProTaper for Hand Use and irrigated. Group I was irrigated using 2.5% NaOCl, group II was irrigated with red pine extract, and group III was irrigated using green pine extract. Tooth that has been prepared, were cut vertically into 2 and cut horizontally in 1/3 apical section. The root canal surface was observed using a scanning electron microscope. Photomicrograph was observed by three observers using a score and performed an analysis test. Results: There were no difference between red pine (Pinus densiflora) and green pine (Pinus merkusii) in root canal cleanliness with a significance value of 0.169 (p> 0.05) Conclusion: Red pine extract had the same smear layer cleaning power as green pine extract.
THE EFFECT OF COMBINATION CALCIUM HYDROXIDE-PROPOLIS APPLICATION TO AMOUNT OF NEUTROFIL CELLS ON WISTAR RAT PULP PERFORATION Ira Widjiastuti; Setyabudi Setyabudi; Nia Nur Haliza
Conservative Dentistry Journal Vol. 10 No. 2 (2020): July-December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v10i2.2020.66-70

Abstract

Background: Pulp inflammation can be treated with pulp capping by calcium hydroxide as the gold standard. Pulp capping by calcium hydroxide could causing tissue necrosis followed by inflammation. Calcium hydroxide combined with propolis which have anti-inflammatory effects through inhibition of the Nf-kB pathway and pro-inflammatory cytokines. That process will inhibit the increase of vascular permeability and neutrophil chemotaxis. Inflammatory process can accelerate by controlling the amount of neutrophil cells as a acute phase marker, so the healing process occurs more quickly. Therefore it is necessary to study the amount of neutrophil cells in the pulp perforation of Wistar rats after applicated by combination of calcium hydroxide-propolis. Purpose: To analyze the difference amount of neutrophil cells on the Wistar rats pulp perforation after applicated by calcium hydroxide-propolis combination compared with calcium hydroxide-aquadest Method: M1 tooth perforated for all groups with three types tratment: no medication (control group), calcium hydroxide-aquadest 1: 1 (P-1 group), and calcium hydroxide-propolis 1: 1.5 (P-2 group) and closed with cention. Observations were made on the 1st, and 3rd day with HE staining. Results: One Way ANOVA shown a significant difference (p <0.05) of the average amount of neutrophil cells between all treatment groups on 1st day (p=0,000) and 3rd day (p=0,000). The amount of neutrophil cells in the calcium hydroxide-propolis (P-2) combination group was lower than control group and calcium hydroxide-aquadest (P-1) group on the 1st and 3rd day. Conclusion: The amount of neutrophil cells after application of calcium hydroxide-propolis is lower than calcium hydroxide-aquadest application.
Antioxidant Potential of Epigallocatechin-3-gallate, Ascorbic Acid, and Sodium Ascorbate in Solution and Gel Forms by 2,2-diphenyl-1-picrylhydrazyl (DPPH) Assay Virdah Dwi Dewaantari; Setyabudi Setyabudi; Kun Ismiyatin
Conservative Dentistry Journal Vol. 11 No. 1 (2021): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v11i1.2021.19-23

Abstract

Background: Free radicals are molecules without any electron pairs, unstable, and highly reactive. Antioxidants are needed to reduce free radicals. Antioxidants provide various benefits in dentistry as a preventive agent for caries, healing, bone formation, mouthwash, preventive and therapeutic cancer, and reduction of periodontal disease progressions. Additionally, research on antioxidants is still undergone due to the existence of free radical residues on bleached teeth. Epigallocatechin-3-gallate (EGCG), ascorbic acid (AA), and sodium ascorbate (SA) are ingridients that have antioxidant properties. Antioxidants can be in two forms solution and gel. Solutions have a higher substance releasing power than gel. Gel is extremely adhesive, so it does not flow easily. Meanwhile, solutions are rather unstable because it flows easily. Antioxidant activities were evaluated with 2,2-diphenyl-1-picrylhydrazyl (DPPH) Assay method. Purpose: Analyzing through literature reviews the potential antioxidants of EGCG, AA, and SA in solution and gel forms by DPPH Assay. Reviews: There were eight journal articles used in this review. The first article described antioxidant solutions in which EGCG was higher than sodium ascorbate. The second article showed that antioxidant gel EGCG was lower than sodium ascorbate. The third journal explained that ascorbic acid was higher than sodium ascorbate both in solution and gel forms. The other articles provided some information about the antioxidant activity percentages of EGCG, SA, and AA in the forms of gel and solutions by DPPH assay. Conclusion: EGCG has a higher antioxidant activity than SA, but it is lower when compared to AA in both solution and gel forms by DPPH assay.
Photodynamic Therapy 405 nm Diode Laser as Antibacterial for Cavity and Root Canal Sterilization Tasya Nafatila Chalisha; Nadira Nurin Febrianti; Sri Kunarti; Setyabudi Setyabudi
Conservative Dentistry Journal Vol. 11 No. 2 (2021): July - December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v11i2.2021.62-66

Abstract

Background: The goals of caries restoration and endodontic treatment are to repair and prevent the infection fromgetting worse and if possible, heal the damaged tissue. To achieve this goal, it is necessary to control the presence ofmicrobes in the cavity or root canals with chemo mechanics prior to filling or obturation of the root canals. Disinfectionmethods using disinfectants with effective bactericidal activity are mostly used at subtoxic levels and at concentrationswhere their toxicity is a significant factor. In addition, the disinfection method is considered unable to achieve thoroughcavity cleaning and causes secondary infection. A new method to provide better disinfection without cytotoxic effectshas recently been discovered using the photodynamic method of 405 nm diode laser therapy. Research continues and isprogressing with the existence of various factors that affect the effectiveness of the 405nm diode laser as an antibacterial.Purpose: To evaluate the results of research on photodynamic diode laser therapy with a wavelength of 405 nm as acombination antibacterial therapy in cavity and root canal sterilization techniques. Review(s): Literature study in the formof narrative review using libraries obtained through the PubMed and Google Scholar databases. The optimal bacterialmortality was influenced by the form factor of the target bacteria, the energy dose and duration of laser exposure, and thetype of photosensitizer used. Conclusion: The use of a 405 nm diode laser with an energy power of 50 mW with a distanceof 20 mm can degrade biofilms Streptococcus mutans up to 100% using erythrosine photosensitizer, for 75 seconds. Andwith the same power and distance, it can degrade the biofilm of bacteria Enterococcus fecalis up to 97.51%, using aphotosensitizer chlorophyll, for 120 seconds.
A Mixture of Ceramic Biomaterials (Hydroxyapatite and β-Tricalcium Phosphate) and Chitosan as a Scaffold For Critical Sized Defect Bone Dian Agustin Wahjuningrum; S. Setyabudi; Fery Setiawan; Dwikora Novembri Utomo; Ria Chusnita; Andi Syahrimayani; Arif Rahman Nurdianto
Conservative Dentistry Journal Vol. 11 No. 2 (2021): July - December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v11i2.2021.93-97

Abstract

Background: Bone is a living tissue that undergoes a continuous regeneration-remodeling process and the second largest organ implanted after the blood transfusion process. Bones can heal completely, but Critical Size Defects (CSD) require graft materials to support the healing process. There are several graft materials, namely: autologous, allogenous, xenograft, and alloplastic material with their respective advantages and disadvantages through the properties: osteogenesis, osteoconduction, osteoinduction, and others. One of the alloplastic materials is Hydroxypatite/HA and β-Tricalcium Phosphate/β-TCP widely used in the grafting process. HA has the disadvantage of having a low degree of solubility, while β-TCP has a high solubility level when exposed to body fluids. Purpose: To explain the mixture of ceramic biomaterials (Hydroxyapatite and β-Tricalcium Phosphate) and Chitosan as a Scaffold for Critical Sized Defect Bone. Methods: This study used article based review from some journals that contain of the review about HA and -TCP. Results: The CSDs are condition where the bone can not heal by itself. It needs bone graft to bridge the heal of CSDs. One of the transplant materials is ceramic biomaterials contains of HA and β-TCP. Each of material has its strengths and weaknesses so that mixture of these ingredients will increase the positive effects and reduce the negative effects of each ingredient. Conclusion: CSD healing requires a scaffold that mimics cancellous bone in the healing process of bone defects played by the mixture of BCP as a bioceramic material and chitosan as a natural biopolymer with low toxicity and high biocompatibility.
The Use of Artificial Intelligence in New Normal Era Against Pandemic COVID-19 in the Field of Health Services Dian Agustin Wahjuningrum; Fery Setiawan; Setyabudi; Heni Puspitasari; Ahmad Yudianto; Agung Sosiawan; Arif Rahman Nurdianto; Swadheena Patro
Conservative Dentistry Journal Vol. 12 No. 1 (2022): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v12i1.2022.12-19

Abstract

Background: Indonesia is currently experiencing Coronavirus Disease-19 (COVID-19) pandemic which affects all sectors of life, therefore Indonesia is starting to prepare for New Normal era, including in health care sector. COVID-19 was previously known as novel Coronavirus Disease-19 (nCoV-19), where World Health Organization (WHO) declared it as a global pandemic in March 2020. New Normal era is an era of coexistence with COVID-19, resulting in new habits that were rarely or never practiced before. One practice that can be applied in health care sector is to use Artificial Intelligence (AI) to treat COVID-19 patients to prevent casualties for health workers. Health care providers are prone to contract aerosol and droplet transmission while treating patients, resulting in cytokine storm, acute respiratory distress syndrome (ARDS), and acute lung injury (ALI), which leads to death. Purpose: This mini review study used to explain the using of artificial intelligence in the new normal era against pandemic COVID-19 in the field of health services. Reviews: This pandemic COVID-19 restricts all of the communication between person to person. It also challenged the health service sector because the health service sector is the first line to combat the COVID-19. It is now popular to use artificial intelligence. This using can be used to help the health service sector in combating the COVID-19 pandemic especially in this new normal era. Conclusion: COVID-19 pandemic affects all aspects of life, especially health care sector, therefore AI use is important to prevent the deaths of health workers because of this pandemic.