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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Mutiara Medika: Jurnal Kedokteran dan Kesehatan Biomedika The Indonesian Biomedical Journal Universa Medicina Communications in Science and Technology Indonesian Journal of Biomedicine and Clinical Sciences Berkala Ilmiah Kedokteran dan Kesehatan Masyarakat Cermin Dunia Kedokteran
Adika Zhulhi Arjana
Faculty Of Medicine, Universitas Negeri Yogyakarta, Yogyakarta
Biochemistry, Genetics & Molecular Biology Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : Cermin Dunia Kedokteran

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Tinjauan Imunologi pada Fenomena Non-Responder terhadap Vaksinasi Hepatitis B: Analisis Arjana, Adika Zhulhi; Devita, Ninda
Cermin Dunia Kedokteran Vol 52 No 4 (2025): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i4.1437

Abstract

Hepatitis B vaccine has been highly effective in preventing HBV infection. However, a subset of individuals fails to develop adequate protective antibodies after complete vaccination series (anti-HBs ≥ 10 mIU/mL), termed as non-responders. Non-responder phenomenon is influenced by a complex interplay of genetic, immunological, and environmental factors. This narrative review aims to delve into the immunological aspects of the non-responder phenomenon, exploring the factors influencing vaccine response, the immunological mechanisms involved, and potential approaches to managing and overcoming non-responders.
Co-Authors Anak Agung Gede Sugianthara Budi Mulyono Budi Mulyono Ester Tri Rahayu Ester Tri Rahayu Habibah, Ulil Albab Harina Salim Ika Fidianingsih Irfan, Mohammad Rozan Irfan, Rozan Muhammad Irfan, Rozan Muhammad Juwariyah Juwariyah Juwariyah Juwariyah Khoiriyah, Umatul Linda Rosita Marsetyawan HNE Soesatyo Mohammad Juffrie, Mohammad Muhammad Juffrie Mulyaningrum, Utami Mulyono, Budi Ninda Devita Ninda Devita, Ninda Novenanto, Tandean Tommy Nurmasitoh, Titis Rahayu, Ester Tri Rahayu, Ester Tri Rahmat Dani Satria Rina Susilowati Rozan Muhammad Irfan Rozan Muhammad Irfan Rozan Muhammad Irfan Supomo Tandean Tommy Novenanto Tri Ratnaningsih Umi S. Intansari Ida Savitri Laksanawati Usi Sukorini Utami Mulyaningrum Yanri W Subronto Yuantari, Rahma Yunika Puspa Dewi