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All Journal Indonesian Journal of Chemical Analysis (IJCA) Jurnal Jejaring Matematika dan Sains Jurnal Ilmu Ekonomi Jurnal Abdimas Bina Bangsa CHEDS: Journal of Chemistry, Education, and Science Prosiding University Research Colloquium Diteksi : Jurnal Pengabdian Kepada Masyarakat
Sulistiawati, Putri
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Journal : Prosiding University Research Colloquium

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Antiobesity Activity of Iles-Iles (Amorphophallus onchophyllus) Tuber Flour in Obesity Rat Model Sulistiawati, Putri; Muhtadi, Muhtadi
Prosiding University Research Colloquium Proceeding of The 15th University Research Colloquium 2022: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Obesity is a condition that occurs when the quantity of body fat tissue is greater than the total body weight than normal, or the body experiences excess fat accumulation which causes a person's weight to be far above normal. Obesity occurs because the imbalance between energy from food intake is greater than the energy used by the body. Iles-iles tuber plant from the Araceae tribe is one of the plants used as natural medicine because the nature of the plant can cause physiological activities in the human body. The purpose of this study was to determine the anti-obesity activity of Iles-iles tuber flour (Amorphophallus onchophyllus) in a model of obese Wistar rats. Iles-iles tubers contain glucomannan which is used for treatment. A total of 25 male Wistar rats were divided into 5 groups consisting of negative given 1% PGS, positive control group was given orlistat 15.6 mg/kg.BW, and 3 treatment groups were given extracts. iles-iles tuber flour doses of 25, 50, and 100 mg/kg.BW for 14 days. Previously, an increase in body mass was carried out to become obese for 21 days and then observed changes in body weight and body length of rats for 14 days, the results of which were used to calculate the Lee index. The results showed that there was no significant difference between day 21 and day 35 in all groups with a significance of p>0.05.
Co-Authors Akhmad Zaini, Akhmad Ariska, Risya Cahya Ningrum, Rafika Dongoran, Junita Dwi Anung Nindito Dwi Wulandari, Putri Evasufi Widi Fajari, Laksmi Faisal, Putri Hasanah, Siti Fadillah Jeddah Yanti Karima Fasya, Nada Kudadiri, Puput Khairani Mahdi Santoso Maknun, Luluil Marvin Horale Pasaribu Mokhamat Ariefin Muhtadi Muhtadi Mulyanah Nafisah, Zahrotun Ningrum, Faradita Ersanti Noor Hamidah, Noor Nurul Aeni Paksi, Pandu Gizta Rapi Pitriah Pramana, Andika Puji Lestari, Nathalia Ramadhan, Mutiara Rizki Rachmad Saputra Rusanisari, Anna Sari, Meiyanti Ratna Kumala Silaen, Cindy Claudia Br Simangunsong, Sri Yulandari Siska, Amelia Syahrozi, Syahrozi Tampubolon, Mulani Jeni Lestari Ujang jamaludin, Ujang Widiastuti Wijaya, Putri