Article Per Year (5 Year)
p-Index From 2020 - 2025
1.554
P-Index
This Author published in this journals
All Journal Narra J The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia International Journal of Cell and Biomedical Science
Ardani, Yanuar
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 9 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 5 Documents
Search
Journal : International Journal of Cell and Biomedical Science

 1 
Psycho-Neuro-Autonomic Aspect of Burnout Syndrome: A Literature Review Oliviera, Ivona; Ardani, Yanuar; Shatri, Hamzah
International Journal of Cell and Biomedical Science Vol 2 No 6 (2023)
Publisher : Stem Cell and Cancer Research (SCCR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59278/cbs.v2i6.40

Abstract

Background: Burnout syndrome are symptoms resulting from stress due to burden and stressors of high workload, as seen in health workers. Burnout syndrome can trigger psychological and physiological disorders, mainly related to the autonomic nervous system and the Hypothalamus-Hypophysis Axis pathway. Psychological disorders could be assessed using Maslach Burnout Inventory (MBI), while physiological disorders of the neuro-autonomic imbalance could be assessed using Heart Rate Variability (HRV). Aim: To study about the psycho-neurological aspect of burnout syndrome. Methods: A systematic literature review using the PRISMA method, through four stages, namely identification, screening, feasibility, and accepted results. Results: Literature search was performed using PubMed and Google Scholar databases. Seven articles fulfilled the inclusion criteria. Five out of seven articles showed association between HRV and burnout score, while two articles showed no association between HRV and burnout score. Discussion: In the presence of stress, the autonomic nervous system activates the amygdala and hypothalamus, which subsequently triggers response from the adrenal gland to produce noradrenaline, which in turn affects the autonomic nervous system. A low HRV signifies inflexibility of the sympathetic and parasympathetic nervous system. Contradicting results may be caused by difference in sample and HRV confounding factors such as difference of physical activity, exercise, underlying disease, medication. Conclusion: There is an association between burnout score and HRV, which implies the presence of neuro-autonomic dysfunction in burnout patients. Further research is needed to rule out confounding factors.
Heart Rate Variability as a Prognostic Tool for Palliative Patient : A Literature Review Charlex, Harold Jefferson Matthew; Ardani, Yanuar; Shatri, Hamzah
International Journal of Cell and Biomedical Science Vol 2 No 5 (2023)
Publisher : Stem Cell and Cancer Research (SCCR)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Heart rate variability (HRV) is the fluctuation in the interval between two heartbeats. Decreased HRV indicates less flexibility of the autonomic nervous system (ANS) to physiological changes and is associated with poorer disease progression and mortality in several diseases. We reviewed conditions where HRV can be utilized as a predictive tool for palliative patients. Methods: We performed a comprehensive search in PubMed, ScienceDirect, and Google Scholar to find articles related to HRV and prognosis for cancer-related disorders, cardiovascular disease, and sepsis. 41 relevant articles were selected and reviewed. Results: ANS changes due to chronic cancer pain and metastastic bone cancer can be detected by HRV analysis and increased vagal activity is related with longer survival on advanced cancer patients. Lower HF is a risk factor for shorter life expectancy of metastatic or recurrent breast cancer. SDNN and RMSSD reduction correlates with poorer survival in NSCLC and metastatic brain cancer. Increased risk of stroke was observed in patients with lower RMSSD and SDNN. Reductions of both scores and LF were associated with two times increased risk of myocardial infarction and higher mortality one year after stroke. A decrease in HRV is related to mortality but is not specific to cardiovascular disease. SDNN and HF are HRV parameters that are most consistently correlated with sepsis and can predict mortality within 30 days of hospitalization. Conclusion: HRV analysis helps in assessing the prognosis of diseases. Typically, reduced HRV is linked to worse outcomes and increased mortality rates in conditions such as cancer, cardiovascular disease, and sepsis.
Factors Influencing the Barriers to Performing Five Daily Prayers among Muslim Inpatients at RSUP Dr. Kariadi Sofro, Muchlis Achsan Udji; Ardani, Yanuar; Sammy, Alwi
International Journal of Cell and Biomedical Science Vol 3 No 7 (2024)
Publisher : Stem Cell and Cancer Research (SCCR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59278/cbs.v3i7.45

Abstract

Background: Prayer is a fundamental obligation for Muslims, performed five times daily. For hospitalized Muslim patients, maintaining regular prayer routines can be challenging due to physical limitations, hospital infrastructure barriers, lack of religious knowledge, and insufficient support from healthcare providers. Objective: This study aims to identify the barriers Muslim inpatients face in performing prayers and to propose recommendations for improving spiritual accommodations in hospital settings.Methods: A qualitative study was conducted at RSUP Dr. Kariadi using in-depth interviews and participatory observation. Thirty Muslim inpatients, along with family members and medical personnel, were involved. Data were collected through semi-structured interviews and direct observations, then analyzed using thematic analysis to identify major influencing factors.Results: Physical limitations such as pain (40%), difficulty standing (50%), and movement restrictions from medical devices (33.3%) were key barriers. Facility-related issues, including inaccessible prayer rooms (70%) and lack of prayer aids (55%), significantly impacted patients' ability to pray. Religious knowledge gaps were notable, with 60% of patients unaware of permissible prayer adjustments (rukhsah). Furthermore, 80% reported no assistance from healthcare staff in facilitating prayer. Psychological factors such as stress (30%) and fatigue (25%) also affected patients' motivation, while encouragement from family and staff (50%) positively influenced prayer practices. Conclusion: Muslim inpatients encounter multiple barriers to performing prayers during hospitalization. Structured interventions, including improving hospital facilities, providing religious education, and training healthcare providers in spiritual care, are essential to support the spiritual well-being of Muslim patients.
A 36-Year-Old Male with Snake Bite Grade I Manus Dextra Case Report Dewi, Ratna; Pranandari, Ayun; Ardani, Yanuar
International Journal of Cell and Biomedical Science Vol 3 No 8 (2024)
Publisher : Stem Cell and Cancer Research (SCCR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59278/cbs.v3i8.54

Abstract

Background: Snakebite remains a major global public health concern, particularly in tropical regions like Indonesia. Snake envenomation may lead to local and systemic manifestations including erythema, swelling, pain, hypotension, respiratory distress, and even death. Case: A 34-year-old male presented to the Emergency Department of Esensia Main Clinic with the chief complaint of a traumatic wound on the right hand resembling a snakebite, accompanied by hand swelling, pain, nausea, and dizziness. The patient had applied a cloth bandage prior to arrival. Results: The patient was diagnosed with a grade I snakebite of the right hand (manus dextra) based on clinical history and physical examination. Management included administration of anti-snake venom serum (ASVS). Conclusion: Venomous snakebites can result in severe outcomes, including death; thus, early and appropriate management is crucial. In this case, medical treatment included administration of ASVS.
Human-Umbilical Cord-Mesenchymal Stem Cells (hUC-MCSs) Therapy with Extravesicles (EVs) Booster Improves Recovery in Type 2 Diabetes Mellitus with Cardiovascular Disease Nugraha, Dendi Krisna; Jutadi; Anggoro, Naufal Sebastian; Sari, Fikriya Novita; Ardani, Yanuar
International Journal of Cell and Biomedical Science Vol 4 No 10 (2025)
Publisher : Stem Cell and Cancer Research (SCCR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59278/cbs.v4i10.66

Abstract

Background: Type 2 diabetes (T2DM) is a chronic metabolic disorder characterized by insulin resistance and β-cell dysfunction, leading to persistent hyperglycemia and complications. Studies have explored mesenchymal stem cell (MSC)-based therapies and their extracellular vesicles (EVs) as novel approaches for metabolic regulation and tissue repair. Case: A 43-year-old male patient exhibited symptoms including excessive thirst and hunger, frequent urination, fatigue, and intermittent blurry vision. He had type 2 diabetes and recently worsened symptoms. The obese patient had elevated blood glucose, HbA1c, triglycerides, and uric acid. He received umbilical cord-derived mesenchymal stem cells (161,6 × 106 cells), followed by seven intramuscular EV injections (1.5 cc each), along with diet and antioxidant supplements. Results: Three months after the conclusion of treatment, laboratory test showed significant improvement, with fasting glucose levels measuring at 91 mg/dL, HbA1c levels at 5,1%, triglyceride levels at 151 mg/dL, uric acid levels at 4,9 mg/dL, and an erythrocyte sedimentation rate of 12 mm/hr. The clinical symptoms such as nocturia, fatigue, and neuropathic pain, demonstrated a substantial improvement, as well as led to the resolution of skin xerosis and heel fissures. Conclusion: This case suggests that combined UC-MSC and EV therapy, complemented by lifestyle modification, may contribute to metabolic stabilization and symptomatic relief in T2DM patients.
Co-Authors Achmad Fauzi Anggono, Rendi F. Anggoro, Naufal Sebastian Aulia Rizka, Aulia Browijoyo, Isa A. Charlex, Harold Jefferson Matthew Dadang Makmun Dian R. Sawitri, Dian R. E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Eka Ginanjar Em Yunir, Em Erlita, Diana Faisal, Edward Harry Isbagio Hasan Maulahela, Hasan Heri Wibowo Irman Firmansyah Irvianita, Vinandia Ivona Oliviera, Ivona Jeger, Dian P. Jutadi Katarina, Matilda Masyur, Muhtaruddin Muchlis Achsan Udji Sofro Nugraha, Dendi Krisna Pranandari, Ayun Ratna Dewi Ricardo, William Rudi Putranto Sammy, Alwi Sari, Fikriya Novita Sarwono, Sugeng J. Sinulingga, Dika I. Sukamto Koesnoe Tjhin Wiguna Zulkifly, Steven