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All Journal Indonesian Journal of Pharmaceutical Science and Technology Jurnal Pendidikan Informatika dan Sains GERVASI: Jurnal Pengabdian kepada Masyarakat Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Sains dan Kesehatan
Apridamayanti, Pratiwi
Departemen Farmakologi Dan Farmasi Klinis, Jurusan Farmasi, Fakultas Kedokteran, Universitas Tanjungpura
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Physics Social Sciences Other

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POTENSI SENYAWA ANTIOKSIDAN TANAMAN ENDEMIK PADA MASYARAKAT DAYAK SEKAJANG DI KALIMANTAN BARAT Pratiwi Apridamayanti; Hadi Kurniawan
Jurnal Pendidikan Informatika dan Sains Vol. 7 No. 1 (2018): Jurnal Pendidikan Informatika dan Sains
Publisher : IKIP PGRI Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31571/saintek.v7i1.770

Abstract

Penelitian ini dilakukan untuk mengetahui khasiat tanaman obat yang digunakan secara empiris pada masyarakat dayak di dusun Sekajang. Kelompok masyarakat adat yang berada di dusun Sekajang yaitu Dayak Semuh. Menurut hasil wawancara yang dilakukan terhadap Batra (Pengobat Tradisional) pada penelitian Riset Tanaman Obat dan Jamu tahun 2015 diperoleh ramuan yang digunakan dalam pengobatan nyeri oleh masyarakat dayak sekajang. Ramuan yang digunakan terdiri  daun buluh (Bambusa vulgaris), daun sak (Melastoma malabathricum), kulit batang langsat (Lansium domesticum correa), daun saoh, daun empedu. Pada penelitian ini proses ekstraksi dilakukan secara maserasi menggunakan etanol 95%. Dilakukan uji metabolit kandungan senyawa kimia dan uji aktivitas antioksidan dengan menggunakan DPPH. Hasil identifikasi terhadap kandungan metabolit sekunder senyawa diperoleh adalah alkaloid, fenol, tannin, flavonoid, saponin, dan terpenoid. Nilai aktivitas antioksidan yang dimiliki masing-masing ekstrak yaitu Daun Buluh (Bambusa vulgaris) 67%, Daun Sak (Melastoma malabathricum) 64%,  Kulit Batang Langsat (Lansium domesticum correa) 55,6%, Daun Empedu 64,98 %, dan Daun Saoh 73,02%.Kata Kunci:  Antioksidan , DPPH, Dusun Sekajang, Tanaman Endemik.
Comparison Ability of Polymers Acrycoat S100 And HPMC K4M to Entrapment Efficiency Domperidone in Microspheres Pratiwi Apridamayanti; Nora Nurlina Sinaga; Rise Desnita
Indonesian Journal of Pharmaceutical Science and Technology Vol 7, No 1 (2020)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v7i1.18461

Abstract

Domperidone is a prokinetic and antiemetic agent which has low bioavaibility. To increase the bioavaibility of drug, it can be modified into microsphere that can hold drug more longer in gastric to improve the bioavaibility. The microsphere preparation requires a polymer that can make matrix system to protect and deliver the drugs. Acrycoat S100 and HPMC K4M are the usual polymers that used for encapsulation and  have biodegradable characteristic. The aim of this research is to know the comparison ability of two different polymers to entrapment the drug in microsphere. Microsphere domperidone made by solvent evaporation method in 6 formula. F1, F2 and F3 using 50 mg, 100 mg and 150 mg Acrycoat S100 polymer, while F4, F5 and F6 using 50 mg, 100 mg and 150 mg HPMC K4m polymer. The tests were conducted by the determination of the percentage of entrapment efficiency using UV spectrophotometer and evaluation of organoleptic, particle measurement and surface microsphere morphology. The results showed that F3 with Acrycoat S100 polymer has a greater entrapment efficiency of 78,712% ± 4,260% compared to the highest percentage efficiency of HPMC K4M polymer of 4,734±0,390.Key words: Acrycoat S100, domperidone, entrapment efficiency, HPMC K4M, microsphere
PELATIHAN PEMBUATAN SABUN CAIR LIDAH BUAYA PADA KELOMPOK ASPELIYA PONTIANAK Robiyanto Robiyanto; Rafika Sari; Pratiwi Apridamayanti; Eka Kartika Untari
GERVASI: Jurnal Pengabdian kepada Masyarakat Vol 1, No 1 (2017): GERVASI: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPM IKIP PGRI Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31571/gervasi.v1i1.664

Abstract

Kecamatan Pontianak Utara merupakan pusat industri di Kota Pontianak yang salah satunya dikenal sebagai produsen minuman lidah buaya. Hasil samping produk olahan lidah buaya adalah kulit lidah buaya yang sering tidak dimanfaatkan oleh pihak produsen. Limbah kulit lidah buaya diketahui memiliki potensi sebagai antibakteri. Tujuan kegiatan pengabdian adalah untuk memanfaatkan limbah kulit lidah buaya menjadi sabun cair dalam bentuk pelatihan kepada produsen industri rumah tangga lidah buaya yang tergabung dalam kelompok Aspeliya (Asosiasi Pengusaha Lidah Buaya) Kota Pontianak. Formulasi sabun cair lidah buaya terdiri dari infusa kulit lidah buaya 30%, basis terdiri dari 3 minyak (minyak zaitun, minyak kelapa, dan minyak dengan perbandingan 1:1:1), asam stearate 2%, HPMC 3%, gliserin 18,75%, larutan KOH 10%, BHT 0,02%, dan akuades ad 100 ml. Uji pH, uji kadar asam lemak bebas dan alkali bebas, uji organoleptik, tinggi busa, viskositas serta bobot jenis dilakukan setelahnya. Saat pelatihan, peserta diminta untuk praktik langsung membuat sabun cair dengan bimbingan dari narasumber. Pelatihan diakhiri dengan sesi tanya jawab dan penyebaran kuesioner. Kesimpulan dari kegiatan pengabdian yaitu seluruh peserta merasakan manfaat dan termotivasi dengan adanya pelatihan. Para peserta juga berharap untuk mendapatkan pelatihan produk olahan lainnya untuk menambah pengetahuan. Kata Kunci: sabun cair, lidah buaya. AbstractPontianak Utara District is industrial centres of Pontianak city, one of them is known as aloe vera drink producing centre. Waste of the aloe vera drink product is the leave skin which is unused by producer. The aloe vera leave skin has been reported to have antibacterial effect. The purpose of this community service activity was to utilize unused aloe vera leave skin to be liquid soap by giving a workshop to home industry of aloe vera producers whom are members of Aspeliya group in Pontianak. The formulation of aloe vera liquid soap consisted of skin infusum 30%, bases (olive oil, coconut oil, and castor oil = 1:1:1), stearic acid 2%, HPMC 3%, glycerin 18,75%, KOH soln 10%, BHT 0,02%, and aquadest ad 100 ml. Acidity test (pH), free fatty acid level and free alkaline test, organoleptic test, foaming height, viscosity and density test were also conducted. During the workshop, participants were asked to practice making liquid soap with tutorial from the speaker.This workshop was finished with QA session and questionnaire distribution. The conclusion of this workshop was all participants feltthe benefit and motivated.They also expected to join another similar workshop to make other processed products to enrich their knowledge. Keywords:liquid soap, aloe vera.
Pengaruh Pemberian Lozenges Kombinasi Kulit Pisang dan Kulit Nanas terhadap Tikus Putih (Rattus norvegicus L.) galur Wistar Adelita Ahyanurri; Liza Pratiwi; Hadi Kurniawan; Inarah Fajriaty; Siti Nani Nurbaeti; Nugraha Fajar; Pratiwi Apridamayanti
Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i1.13811

Abstract

Banana peel and pineapple peel have high potassium content. The banana peel and pineapple peel combination can be used as lozenges in potassium supportive therapy. The safety of banana peel and pineapple peel combination lozenges must be ensured by the acute toxicity test. One of the parameters observed during toxicity testing is the organ index. This study aims to determine the relationship between dose and toxicity in acute oral administration of banana peel and pineapple peel combination lozenges on the heart, lungs, liver, spleen, and kidneys organ index in white rats (Rattus norvegicus L.) Wistar strain. Acute toxicity based on OECD 425 guidelines for the Up-and-Down Procedure (UDP) method. Rats were grouped into 2000 mg/kg BW and 5000 mg/kg BW dose groups, consisting of 5 rats. Organ indexes were analyzed using SPSS Independent Sample T-test with 95% confidence level (p0.05). The result showed no significant difference between both doses (P0.05) in heart, lungs, liver, spleen, and kidneys organ index. Based on the results, it can be concluded that banana peel and pineapple peel combination lozenges did not affect white rats’ heart, lungs, liver, spleen, and kidney organ index.
Pengaruh Ekstrak Kulit Pisang dan Kulit Nanas terhadap Aktivitas Motorik dan Perilaku Tikus Wistar Novia Novia; Fajar Nugraha; Siti Nani Nurbaeti; Inarah Fajriaty; Pratiwi Apridamayanti; Hadi Kurniawan; Liza Pratiwi
Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i1.13908

Abstract

Banana peel and pineapple peel are organic wastes that contain potassium, so it can potentially be developed into lozenges form as supportive antihypertensive therapy. Banana peel and pineapple peel as health supplement ingredients must meet safety requirements. The study of subchronic toxicity test was aimed to determine the toxic effect of repeated administration of a combination of banana peel and pineapple peel extract on motor activity and behavior of Wistar rats. The study was conducted by giving the test preparations repeatedly for 28 days in the control group, doses of 100 mg/KgBW, 400 mg/KgBW, 1000 mg/KgBW, control satellite, and satellite at 1000 mg/KgBW dose, as well as additional 14 days of observation in the satellite group to observe the reversibility effect. The test results showed that administering a combination of banana peel and pineapple peel extract showed normal observation on motor activity and behavior of Wistar rats. This study concludes that the combination of banana peel and pineapple peel did not give toxic effect on motor activity and behavior of Wistar rats.
Pengaruh Pemberian Ekstrak Kulit Pisang dan Kulit Nanas terhadap Kadar Kalium Tikus Putih Wistar Hiqbar Hiqbar; Hadi Kurniawan; Pratiwi Apridamayanti
Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i1.13633

Abstract

The waste of banana peels and pineapple peels in its utilization is still very lacking, even though it has the potential to be developed because they have high potassium as potassium intake in the body. The combination of banana peel extract and pineapple peel extract is expected to have a synergistic effect as a potassium supplement. The purpose of this study was to determine serum potassium levels of rats (Rattus norvegicus L.) Wistar with banana peel and pineapple peel extracts. Banana peel and pineapple peel were extracted using the infusion method. The test animals used male and female Wistar rats. The control group was given glucose and sucrose bases, the test group was given doses of 100, 400, and 1000 mg/KgBW of banana peel and pineapple peel extract with glucose and sucrose bases, and the control satellite group and satellite dose of 1000 mg/KgBW. The results of all groups showed normal levels of potassium in blood serum. Potassium levels between each group did not show a significant difference (p≥0.05) in male and female rats. Conclusion: administration of banana peel and pineapple peel extract did not affect the serum potassium level of Wistar rats.
Pengaruh Pemberian Kombinasi Ekstrak Kulit Pisang dan Kulit Nanas terhadap Indeks Organ Tikus Wistar Melania Niken Safira; Pratiwi Apridamayanti; Hadi Kurniawan; Inarah Fajriaty; Fajar Nugraha; Siti Nani Nurbaeti; Liza Pratiwi
Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i1.13910

Abstract

Banana peel and pineapple peel contain potassium which may be developed into health supplements. The development of banana peels and pineapple peels as ingredients for potassium supplements must meet safety aspects that can be proven by subchronic toxicity tests. This subchronic toxicity test aimed to determine the effect of repeated administration of a combination of banana peel and pineapple peel extract for 28 days on the liver, kidney, kidney, lung, heart, and spleen index of Wistar rats. This research used male and female white rats which were divided into six treatment groups, namely the control group, low dose, middle dose, high dose, satellite control, and high dose satellite. The results showed that there was a significant increase in the liver and kidney organ index, and a significant decrease in the adrenal gland organ index after administration of a combination of banana peel and pineapple peel extract. This research concludes that the combination of banana peel and pineapple peel extract has an effect on the liver, kidney, and adrenal gland organ index in Wistar white rats.
Analisis Kadar Kalium Ekstrak Kombinasi Kulit Pisang (Musa paradisiaca L.) dan Kulit Nanas (Ananas comosus (L.) Merr) Secara Spektrofotometri Serapan Atom: Analysis of Potassium Levels in Combination Extracts of Banana Peels (Musa paradisiaca L.) and Pineapple Peels (Ananas comosus (L.) Merr) by Atomic Absorption Spectrophotometry Fajar Nugraha; Pratiwi Apridamayanti; Hadi Kurniawan; Inarah Fajriaty; Siti Nani Nurbaeti; Liza Pratiwi; Safrilla Anggraeni
Jurnal Sains dan Kesehatan Vol. 3 No. 6 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i6.791

Abstract

Penggunaan buah pisang dan nanas yang banyak untuk berbagai olahan makanan akan menghasilkan penumpukan limbah kulit. Limbah kulit pisang dan nanas diketahui mengandung unsur kalium yang dapat diolah kembali untuk menjadi produk yang bermanfaat. Oleh karena itu, penelitian ini dilakukan untuk melihat kadar kalium terhadap ekstrak kombinasi kulit pisang dan kulit nanas dengan menggunakan spektrofotometer serapan atom. Metode: pembuatan ekstrak kental dilakukan dengan metode infundasi atau infusa yang dikeringkan. Ekstrak kental didestruksi dengan cara pengabuan menggunakan tanur. Kemudian dilakukan pengujian kadar kalium menggunakan spektrofotometer serapan atom pada panjang gelombang 766,5 nm. Hasil penelitian menunjukkan kalium pada ekstrak kental didapatkan sebanyak 47,483 mg/g ekstrak. Kesimpulan: ekstrak kombinasi kulit pisang dan kulit nanas mengandung kalium yang berpotensi dalam menunjang kebutuhan kalium di dalam tubuh.
Co-Authors Adelita Ahyanurri Eka Kartika Untari Fajar Nugraha Fajriaty, Inarah Hadi Kurniawan Hiqbar Hiqbar Indira Diah Puspita Liza Pratiwi Melania Niken Safira Melly Octaviani Nora Nurlina Sinaga Novia Novia Rafika Sari Rafika Sari Rise Desnita, Rise Robiyanto, Robiyanto Safrilla Anggraeni Siti Nani Nurbaeti