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All Journal Jurnal Pengabdian Kepada Masyarakat Ungu ( Abdi Ke Ungu) JIFI (Jurnal Ilmiah Farmasi Imelda) JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Dedikasi: Jurnal Pengabdian Pendidikan dan Teknologi Masyarakat Journal of Innovative and Creativity Ners Akademika International Journal of Contemporary Sciences (IJCS) Dedikasi: Jurnal Pengabdian Pendidikan dan Teknologi Masyarakat
Daskar, Annajim
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Formulasi Dan Uji Aktivitas Antioksidan Sediaan Sabun Cair Ekstrak Daun Pepaya (Carica Papaya L.) Menggunakan Metode Dpph (2,2-Diphenyl-1-Picrylhydrazyl) Novita, Riska Reza; Daskar, Annajim; Suswidiantoro, Vicko; Rosanti, Afi Sania
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.3487

Abstract

Daun pepaya (Carica papaya L.) mengandung senyawa aktif seperti flavonoid, alkaloid, tanin, dan vitamin C yang berfungsi sebagai antioksidan. Antioksidan sendiri berperan penting dalam menetralisir radikal bebas yang dapat merusak jaringan kulit serta dapat mempercepat proses penuaan. Dalam sediaan sabun cair, penambahan bahan alami yang bersifat antioksidan tidak hanya berfungsi sebagai pembersih, tetapi juga dapat memberikan manfaat protektif terhadap kulit dari efek buruk lingkungan, seperti polusi dan paparan sinar UV. Oleh karena itu, formulasi sabun cair yang mengandung ekstrak daun pepaya (Carica papaya L.) berpotensi sebagai sediaan fungsional yang mendukung kesehatan kulit sekaligus memberikan efek perawatan. Tujuan dari penelitian ini adalah untuk mengetahui formula sabun cair ekstrak daun pepaya yang memiliki aktivitas antioksidan terbaik berdasarkan nilai IC₅₀ menggunakan metode DPPH. Penelitian eksperimental ini memformulasikan sediaan sabun cair dengan variasi konsentrasi ekstrak daun pepaya sebesar 6%, 8%, 10%, dan 12%. Evaluasi dilakukan terhadap parameter organoleptik, pH, tinggi busa, viskositas, homogenitas, stabilitas, dan aktivitas antioksidan menggunakan metode DPPH, yang dibaca pada spektrofotometer UV-Vis. Formula dengan konsentrasi ekstrak 10% (F3) menunjukkan nilai IC₅₀ sebesar 103,89 ppm, yang tergolong aktivitas antioksidan sedang. Formula F3 dinyatakan sebagai formula terbaik berdasarkan aktivitas antioksidannya karena memiliki nilai IC₅₀ yang paling rendah, sehingga menunjukkan potensi antioksidan yang lebih kuat dibandingkan dengan formula lainnya. Kata kunci : Daun pepaya, sabun cair, antioksidan, DPPH, IC₅₀.   ABSTRACT Papaya leaf (Carica papaya L.) contain active compounds such as flavonoids, alkaloids, tannins, and vitamin C, which act as antioxidants. Antioxidants play an important role in neutralizing free radicals that can damage skin tissues and accelerate the aging process. In liquid soap formulations, the addition of natural antioxidant ingredients not only functions as a cleanser but also provides protective benefits to the skin against harmful environmental effects such as pollution and UV exposure. Therefore, liquid soap formulated with papaya leaf extract (Carica papaya L.) has the potential to serve as a functional product that supports skin health while offering skincare benefits. This study aimed to determine the best liquid soap formulation containing papaya leaf extract with the highest antioxidant activity based on the IC₅₀ value using the DPPH method. This experimental research formulated liquid soap with varying concentrations of papaya leaf extract at 6%, 8%, 10%, and 12%. Evaluations were carried out on organoleptic parameters, pH, foam height, viscosity, homogeneity, stability, and antioxidant activity using the DPPH method, measured with a UV-Vis spectrophotometer. The formulation with 10% extract concentration (F3) showed an IC₅₀ value of 103.89 ppm, classified as moderate antioxidant activity. F3 was identified as the best formulation based on its antioxidant activity, as it had the lowest IC₅₀ value, indicating stronger antioxidant potential compared to the other formulations.
Pengaruh Variasi Konsentrasi Kombinasi Ekstrak Buah Tomat (Solanum Lycopersicum L) Dan Madu (Mel depuratum) Terhadap Mutu Dan Stabilitas Sediaan Eye Cream Kartika, Jelita; Rosanti, Afi Sania; Daskar, Annajim; Suswidiantoro, Vicko
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.3565

Abstract

Lingkaran hitam di bawah mata (hiperpigmentasi periorbital) merupakan masalah kulit yang umum dan sering diatasi dengan penggunaan eye cream. Bahan alami seperti buah tomat (Solanum lycopersicum L) yang kaya likopen dan vitamin c, serta madu (Mel depuratum) yang memiliki sifat humektan dan antioksidan, berpotensi menjadi kombinasi bahan aktif dalam formulasi eye cream yang efektif dan aman. Penelitian ini bertujuan memformulasikan eye cream dengan variasi konsentrasi kombinasi ekstrak tomat dan madu menggunakan metode Simplex Lattice Design (SLD), serta menentukan formula optimal berdasarkan mutu fisik dan stabilitas sediaan. Variabel yang diuji meliputi organoleptis, homogenitas, pH, daya lekat, daya sebar, viskositas dan stabilitas. Penelitian ini di lakukan di Laboratorium Farmasetika Universitas Aisyah Pringsewu dan laboratorium Bahan Alam Universitas Aisyah Pringsewu pada bulan Juli-Agustus 2025. Hasil analisis pada penelitian ini membuat 6 fomulasi eye cream dengan konsentrasi ekstrak tomat dan madu 2,5:4,5 (F1), 2:5 (F2), 1:6 (F3), 1,5:5,5 (F4) dan 3:4 (F5). Dari penelitian ini dapat disimpulkan bahwa formula optimal eye cream ekstrak tomat (Solanum lycoperscum L) dan madu (Mel depuratum) dapat diperoleh ekstrak tomat 1% dan madu 6% menggunakan metode SLD dengan nilai optimal.
FORMULASI DAN UJI SUN PROTECTION FACTOR (SPF) SEDIAAN KRIM EKSTRAK ETANOL 96% DAGING BUAH LABU SIAM (Sechium edule (Jacq.) Sw.) SECARA IN VITRO Daskar, Annajim; Heldayani, Debby; Baity, Eva Nurul
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.4026

Abstract

Excessive exposure to ultraviolet (UV) rays can cause various damage to the skin, such as premature aging and skin cancer. The use of natural sunscreens is a safe and environmentally friendly alternative. Chayote (Sechium edule (Jacq.) Sw.) is known to contain active compounds such as flavonoids and phenolics that have the potential as photoprotective agents. This study aims to formulate a cream preparation of 96% ethanol extract of chayote flesh and evaluate its physical characteristics and Sun Protection Factor (SPF) value in vitro. This study used an experimental method. The flesh of chayote (Sechium edule (Jacq.) Sw.) was extracted using the maceration method, followed by the development of a topical cream formula and measurement of the Sun Protection Factor (SPF) value in vitro using. Based on the results of physical characteristic tests, all formulas showed compliance with the criteria for good cream quality, except in the protection power test, where reddish spots were observed in formula F2, and in the physical stability test, emulsion phase separation was found. The SPF value increased with increasing extract concentration. Formula F1 showed an SPF of 15.88; F2 16.68; and F3 18.52, categorized as moderate to high protection. Therefore, chayote pulp extract cream has the potential to be a safe and effective natural sunscreen. It can be concluded that the chayote pulp extract cream preparation has the potential to be used as a natural sunscreen.
Co-Authors Artadevy, Nadhila Fahira Baity, Eva Nurul Bayu Satriawan, Ahmad Cahyani, Vanesa Dwi Damayanti Abdul Karim, Dewi Fadia Zahra, Alya Heldayani, Debby Kartika, Jelita Katika Putri, Diah Lestari, Fina Aulika Mayola Pisacha, Iga Melinda, Ersa Mida Pratiwi Muhammad Ridwan Novita, Riska Reza Pisacha, Iga Mayola Pratama, Dimas Feriza Pratama Riza Dwiningrum, Riza Rosanti, Afi Sania Setyani, Elsa Dewi Suswidiantoro, Vicko Sutomo, Ahmad Syaifurrahman, Amir trijayanti, mesi Wina Safutri Wisnu Probo Wijayanto Zahwa, Nabilla