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All Journal Journal of Biomedicine and Translational Research Biomedical Journal of Indonesia Abdimas Universal Jurnal Pengabdian UNDIKMA Jurnal Pengabdian Masyarakat: Humanity and Medicine Bioeksperimen JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Nawawi, Rizki Andini
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Pemberdayaan kelompok ibu rumah tangga sebagai kader bijak antibiotik dalam upaya pengendalian resistensi antibiotik tingkat komunitas Farah Diba, Masayu; Amalia, Ella; Sabrina, Tia; Rivani, Erizka; Zanaria, Rima; Nawawi, Rizki Andini
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 5 No 2 (2024): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V5I2.140

Abstract

Infectious diseases are a threatening health problem in developing countries, including Indonesia. Diseases caused by bacterial infections can be overcome relatively easily after the discovery of various antibiotics. Uncontrolled use of antibiotics will trigger antibiotic resistance. With the incidence of antibiotic resistance, the potential of antibiotics will be reduced in treating infections and diseases in humans, animals and plants. Community service activities aim to provide knowledge to the community about antibiotics, how to use antibiotics wisely, and introduction to the concept of antibiotic resistance. The activities carried out were in the form of empowerment in the form of counseling for the community and assistance in the form of training for groups of prospective antibiotic wise cadres in the Siring Agung Village area. The results of this activity were obtained to increase the insight and knowledge of the community and health cadres about Antibiotic Wisdom, especially the use of antibiotics correctly, how to get them, how to follow up on antibiotic drug waste if it remains. In addition, the community and cadres also have the skills to wash hands properly and correctly using running water and soap independently to prevent transmission of infectious diseases. Furthermore, it is hoped that continuous service activities with similar themes at different layers or levels of society can be carried out in order for the community to know the importance of the principle of using antibiotics wisely so that the incidence of antibiotic drug resistance can be suppressed to increase.
Pemeriksaan Status Gizi Santri Sebagai Upaya Skrining dan Pencegahan Penyakit Infeksi Nawawi, Rizki Andini; Amalia, Ella; Sabrina, Tia; Rivani, Erizka; Zanaria, Rima; Diba, Masayu Farah; Usman, Doni; Al-Fayed, Muhammad Sadad; Zefianto, Zefianto; Ansyori, Achmad Rifky; Mansur, M. Syafi'i
Abdimas Universal Vol. 7 No. 1 (2025): April
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Balikpapan (LPPM UNIBA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36277/abdimasuniversal.v7i1.2396

Abstract

Nutrition is a contributing factor in the maintenance of optimal immune system functions. Disturbances in nutritional status, such as malnutrition, would impact various structures, mediators, and processes in the immune system in responding to pathogenic infections, hence increasing vulnerability to infections. Adolescents are an age group often considered “healthy”, but screening in this age group proves important in reassuring optimal growth and development, which in turn will also impact the next generation. Pesantren is an Indonesian educational institution serving adolescents with a boarding school system, so it is of high importance for adolescent santri to know their own nutritional status in preventing infectious diseases. This community service event was held at Pesantren Thawalib Sriwijaya to inform about the importance of nutritional status in prevention of infectious diseases. The activities comprised of classical counseling and anthropometric measurement of participating santri. There were 42 participating santri attending Madrasah Tsanawiyah (MTs) and Madrasah Aliyah (MA) in this event, and plotting results showed most santri had normal nutritional status. However, nutritional status monitoring and awareness to infectious disease still needs to be kept up, as there are various other factors that may influence the spread of various infectious diseases.
Potential Modulation of Gut Microbiota by Phytochemicals in Managing Noncommunicable Diseases Nawawi, Rizki Andini
Biomedical Journal of Indonesia Vol. 11 No. 3 (2025): Vol 11, No 3, 2025
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v11i3.250

Abstract

Noncommunicable diseases, such as hypertension and type 2 diabetes, remain a leading cause of death worldwide, especially in low- and middle-income countries. Recent research trends revealed possible involvement of the gut microbiota in the pathogenesis of these noncommunicable diseases. This article provides a review of recent research trends on the human gut microbiota’s involvement in hypertension and type 2 diabetes, and the potential of its modulation by natural products. Several mechanisms are proposed to explain how the gut microbiota contributes to the development of hypertension and type 2 diabetes, one of which is by changes in short-chain fatty acids (SCFAs) production. Phytochemicals targeting modulation of the gut microbiota and SCFAs production may show potential in prevention and therapy of hypertension and diabetes. This may be achieved by affecting the composition of the gut microbiota itself and by modulating the microbiota’s metabolic pathways, such as by stimulating synthesis of SCFAs. However, future studies are still needed considering the complexity of factors affecting gut microbiota, as well as the need to develop reproducible methods in studying the gut microbiota and its metabolites in order to further elucidate the role of gut microbiota in health and disease, in order to achieve optimal benefits and better clinical outcomes.
PENINGKATAN LITERASI KESEHATAN TENTANG PENYAKIT INFEKSI EMERGING DAN REEMERGING MELALUI SEMINAR DARING NASIONAL BAGI MAHASISWA DAN TENAGA KESEHATAN Rivani, Erizka; Amalia, Ella; Sabrina, Tia; Diba, Masayu Farah; Nawawi, Rizki Andini; Usman, Doni
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 9 No. 2 (2024): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v9i2.3403

Abstract

Penyakit infeksi emerging dan reemerging merupakan tantangan yang semakin signifikan dalam dunia kesehatan dalam beberapa tahun terakhir, terutama diakibatkan oleh makin berkembangnya globalisasi, urbanisasi, dan juga perkembangan teknologi di dunia. Berbagai penyakit infeksi baru bermunculan, dan penyakit infeksi yang telah dikenal sejak dahulu mengalami perubahan dari segi manifestasi klinik maupun tantangan dalam deteksi dan tata kelola. Hal ini membuat manajemen dari penyakit infeksi emerging dan reemerging menjadi unik dari segi kebaruan dan pengenalan penyakit. Pengabdian masyarakat dalam bentuk seminar bagi tenaga kesehatan diharapkan dapat meningkatkan kewaspadaan akan penyakit, termasuk bagi mahasiswa yang kelak akan menjadi bagian dari praktisi kesehatan. Seminar diadakan secara daring untuk memperluas cakupan acara sehingga dapat diikuti oleh peserta dengan berbagai latar belakang profesi kesehatan dari seluruh Indonesia. Materi yang disampaikan mencakup tantangan klinis dan manajemen penyakit serta peran laboratorium mikrobiologi klinik dalam deteksi dan pencegahan penyakit infeksi emerging dan reemerging. Terdapat peningkatan persentase jawaban benar dan nilai rerata dari post-test yang dikerjakan oleh peserta pasca paparan materi dibandingkan dengan pre-test. Adanya diskusi interaktif setelah paparan juga menunjukkan ketertarikan peserta akan materi yang disampaikan yang dinilai relevan untuk praktik klinis sehari-hari. Kegiatan pengabdian masyarakat ini memberikan dampak positif berupa peningkatan pemahaman dan motivasi peserta untuk menerapkan ilmu yang didapatkan dalam manajemen, deteksi, dan pencegahan penyakit infeksi emerging dan reemerging. Seminar daring diharapkan dan menjadi model edukasi berkelanjutan untuk meningkatkan kesiapsiagaan dalam menghadai perkembangan ilmu kesehatan secara global.
Karamunting Leaf Extract (Rhodomyrtus tomentosa (Aiton) Hassk.) as antibiofilm on Escherichia coli Sabrina, Tia; Mansur, Muhammad Syafi’i; Diba, Masayu Farah; Nawawi, Rizki Andini; Tamzil, Nia Savitri
Bioeksperimen: Jurnal Penelitian Biologi March 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/bioeksperimen.v11i1.10815

Abstract

Escherichia coli is a bacterium that causes many serious infections such as digestive tract, urinary tract and bloodstream infections. One of the main challenges in treating this bacterial infection is the formation of biofilm, which increases bacterial resistance to antibiotics. As an alternative to overcome antibiotic resistance, karamunting has been identified as having antibacterial potential against Gram-negative bacteria, including E. coli. The active compounds in these leaves have been shown to inhibit bacterial growth and biofilm formation. This research describes the activity of karamunting leaf extract against the anti-biofilm E. coli. The thick karamunting leaf extract was then made into three variations of concentration, namely 125µg/mL, 250µg/mL and 500µg/mL. The parameter measured for the eradication test is the thickness of the biofilm which is read using the Elisa Reader 590nm. In this study, the eradication percentages for the three concentrations were obtained -92.15% at a concentration of 125 µg/mL, -187.24% at a concentration of 250 µg/mL and 52.78% at a concentration of 500 µg/mL. Karamunting leaf extract has activity as an antibiofilm against E. coli bacteria. Karamunting leaf extract with a concentration of 500 µg/mL is the Minimum Inhibitory Concentration (MIC) which is effective as an antibiofilm on E. coli.
Diversifikasi Produk Recycling di Bank Sampah KGS Melalui Pembuatan Sabun Cair dari Minyak Jelantah Ahadito, Bijak Riyandi; Palapa, Neza Rahayu; Mukaromah, Laela; Nawawi, Rizki Andini
Jurnal Pengabdian UNDIKMA Vol. 7 No. 2 (2026): May
Publisher : LPPM Universitas Pendidikan Mandalika (UNDIKMA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/jpu.v7i2.20084

Abstract

This community service program aims to enhance the knowledge and skills of administrators, customers, and surrounding community members of KGS Waste Bank in Palembang in utilizing used cooking oil waste through the application of simple technology to produce liquid soap with practical and economic value. The activity was carried out using a socialization approach combined with training on the production of liquid soap from used cooking oil through a cold saponification process. Evaluation instruments consisted of pre-test and post-test assessments, which were subsequently analyzed descriptively. The results of the program showed an improvement in participants’ understanding of the liquid soap production process from used cooking oil, as indicated by an increase in the average score of 16.94 points in the post-test. This activity successfully opened opportunities for product diversification among the program partners and is expected, through this transfer of knowledge, to enrich the portfolio of recycled products they produce.
Prevalence and Antibiotic Susceptibility Pattern of Multidrug-Resistant Pseudomonas aeruginosa in a Tertiary Hospital, South Sumatera, Indonesia Ningtiyas, Salwa Adilah; Saragih, Dinda Azzahrah; Nafisah, Nusyur Azka; Nawawi, Rizki Andini; Rivani, Erizka; Diba, Masayu Farah; Zanaria, Rima
Journal of Biomedicine and Translational Research Vol 12, No 1 (2026): April 2026
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v12i1.29335

Abstract

ABSTRACTBackground: Pseudomonas aeruginosa is a Gram-negative bacterium that causes opportunistic and healthcare-acquired infections. Its ability to rapidly acquire antibiotic resistance complicates treatment, prolongs hospitalization, and increases morbidity, mortality, and healthcare costs. Objective: This study aimed to determine the prevalence and antibiotic susceptibility pattern of multidrug-resistant P. aeruginosa at Dr. Mohammad Hoesin General Hospital, South Sumatera, Indonesia.Methods: A descriptive observational study with a cross-sectional design was conducted using data from the Clinical Microbiology Laboratory and Medical Records Installation of Dr. Mohammad Hoesin General Hospital, Palembang, from May 2022 to April 2023. Data were analyzed univariately and presented through tables, figures, and descriptive summaries.Results: A total of 465 hospitalized patients were found to be infected with P. aeruginosa. Adult patients aged 18–65 years were the most affected (71%). The leading primary diagnoses were diabetic foot ulcer, pneumonia, and sepsis. Most patients were hospitalized for 8–14 days (25.2%). Antibiotic susceptibility testing showed the highest sensitivity to amikacin (94.2%), while the lowest was observed with meropenem and ceftazidime. The resistance profile included 24.7% MDR, 6.7% XDR, 0.9% probable PDR, and 2.4% DTR isolates.Conclusion: P. aeruginosa infections were predominantly found in adult patients with prolonged hospitalization. Amikacin remains the most effective antibiotic, while cefazolin and tigecycline showed poor efficacy. The presence of MDR, XDR, PDR, and DTR strains highlights the urgent need for rational antibiotic use and strengthened antimicrobial stewardship programs. Keywords:Pseudomonas aeruginosa, Hospitalized patients, Antibiotic resistance, Multidrug resistance
Co-Authors Al-Fayed, Muhammad Sadad Ansyori, Achmad Rifky Bijak Riyandi Ahadito Diba, Masayu Farah Ella Amalia, Ella Farah Diba, Masayu Mansur, M. Syafi'i Mansur, Muhammad Syafi’i Mukaromah, Laela Nafisah, Nusyur Azka Ningtiyas, Salwa Adilah Rivani, Erizka Sabrina, Tia Saragih, Dinda Azzahrah Usman, Doni Zanaria, Rima Zefianto, Zefianto