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Laporan kasus: Karsinoma sel skuamosa paru dengan temuan sitologi dan histopatologi Lina, Juliana; Fadillah, Qori; Nadapdap, Marshall Jeremia; Mukti, Ade Indra; Novita, Cut Elvira
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 1 (2024): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i1.5564

Abstract

Kanker paru-paru sel skuamosa merupakan tantangan klinis yang signifikan dengan prognosis yang buruk. Laporan kasus ini menyajikan seorang pasien dengan gejala khas kanker paru-paru sel skuamosa. Hasil histopatologi mendukung temuan sitologi yakni tampak sebaran dan kelompokan sel epitel skuamous yang atipik dan pleomorfik, inti sel bentuk bulat dan oval, N/C ratio meningkat, kromatin kasar dengan anak inti menonjol, sitoplasma minimal dan eosinofilik. Untuk diagnosa yang lebih pasti dibutuhkan pemeriksaan imunohistokimia p40, p63, CK7, CK5/6 untuk prognosis dan terapi. Namun, sampel jaringan yang sangat sedikit dan tidak cukup untuk prosesing di laboratorium berikutnya, sehingga membutuhkan waktu yang lebih lama untuk tindakan berikutnya pada pasien. Kasus ini menyoroti pentingnya deteksi dini dan penatalaksanaan yang tepat untuk meningkatkan prognosis pasien. Laporan kasus ini memberikan wawasan berharga tentang karakteristik klinis dan tantangan dalam pengelolaan kanker paru-paru sel skuamosa.
Nutritional status and its associated factors among children Masdalena, Masdalena; Nadapdap, Marshall Jeremia
Jurnal Prima Medika Sains Vol. 5 No. 2 (2023): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i2.4515

Abstract

This study aimed to analyze the nutritional status of children in these districts, taking into account factors such as age, gender, maternal education, family income, and children's eating patterns. The study used a cross-sectional design, with 279 children aged 1-10 years as subjects. Data were collected by distributing structured questionnaires to the participants’ parents. The data were analyzed using the chi-square test to determine the significance of the relationship between the predictors and nutritional status of the children (α = 0.05). The results showed that maternal education (0.012), parental income (0.001), and eating patterns (0.001) were significantly associated with the nutritional status of children who were stunted and normal. However, for overweight and obese children, maternal education (0.835), parental income (0.951), and eating patterns (0.309) were not predictors of nutritional status. Age and sex did not significantly influence the nutritional status of children in all categories. Family based interventions through health education are needed to improve nutritional literacy so that parents can plan and prepare nutritious meals for their children. The government must provide policies to support families, especially those with low incomes, to ensure the availability of adequate food and access to nutritious food.
Paparan Emisi Gas Kendaraan dan Kebisingan Berhubungan Dengan Tekanan Darah Petugas Pengujian Kendaraan Bermotor Hartono, Hartono; Silalahi, Marlinang Isabella; Nadapdap, Thomson Parluhutan; Manalu, Putranto; Putri, Faradiba Fatillah; Nadapdap, Marshall Jeremia
Jurnal Kesehatan Lingkungan Indonesia Vol 24, No 1 (2025): Februari 2025
Publisher : Master Program of Environmental Health, Faculty of Public Health, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkli.24.1.95-100

Abstract

Latar belakang: Paparan polutan seperti emisi gas kendaraan dan kebisingan yang dihasilkan oleh aktivitas pengujian kendaraan bermotor dapat membahayakan kesehatan petugas. Berbagai literatur telah mengaitkan peningkatan tekanan darah yang dialami pekerja dengan paparan polutan di lingkungan kerja. Penelitian ini bertujuan untuk mengetahui apakah ada hubungan antara emisi gas kendaraan dan kebisingan terhadap tekanan darah pada petugas pengujian kendaraan bermotor.Metode: Penelitian ini menggunakan pendekatan kuantitatif dengan desain cross sectional. Penelitian dilakukan mulai dari Desember 2020 sampai Juni 2021. Populasi pada penelitian ini adalah 54 petugas pengujian kendaraan bermotor Dinas Perhubungan Kabupaten Deli Serdang dan keseluruhan populasi dijadikan sampel (total sampling). Pengukuran paparan karbon monoksida dan hidrokarbon menggunakan emission analyzer AET-2000S. Sedangkan pengukuran kebisingan menggunakan sound level meter. Data dianalisis dengan menggunakan uji Chi Square (α=0,05).Hasil: Hasil penelitian menunjukkan sebanyak 13 petugas terpapar karbon monoksida dengan paparan di atas nilai ambang batas. 25 petugas terpapar hidrokarbon yang melebihi nilai ambang batas. Sebanyak 21 petugas terpapar kebisingan melebihi ambang batas selama bekerja. Dari hasil pengukuran tekanan darah terlihat bahwa 20 orang memiliki tekanan darah di atas 140/90 mmHg. Uji statistik menunjukkan paparan karbon monoksida (0,006), hidrokarbon (0,014) dan kebisingan (0,001) berhubungan signifikan dengan peningkatan tekanan darah pada petugas pengujian kendaraan bermotor.Simpulan: Tindakan pencegahan yang disarankan berupa penggunaan alat pelindung diri selama melakukan pengujian kendaraan bermotor. Selain itu, perlu dilakukan pembatasan jam kerja untuk meminimalisir durasi paparan polutan pada petugas. ABSTRACT Title: Exposure to Vehicle Emissions and Noise in Relation to Blood Pressure Among Motor Vehicle Testing Officers Background: Exposure to pollutants, such as vehicle gas emissions and noise generated by motor vehicle testing activities, can jeopardize officers' health. Various studies have linked the increase in blood pressure experienced by workers with exposure to pollutants in the work environment. This study aimed to determine whether there is a relationship between vehicle gas emissions and noise on blood pressure among motor vehicle testing officers.Method: This study used a quantitative approach with a cross-sectional design. This study was conducted from December 2020 to June 2021. The population in this study was 54 motor vehicle testing officers of the Deli Serdang Regency Transportation Office, and the entire population was sampled (total sampling). Carbon monoxide and hydrocarbon exposure was measured using an AET-2000S emission analyzer. Noise measurements were performed using a sound-level meter. Data were analyzed using the chi-square test (α=0.05).Result: The results showed that 13 officers were exposed to carbon monoxide with exposure above the threshold value. 25 officers were exposed to hydrocarbons that exceeded the threshold value. A total of 21 officers were exposed to noise exceeding the threshold during work. Blood pressure measurements showed that 20 people had a blood pressure above 140/90 mmHg. Statistical tests showed that exposure to carbon monoxide (0.006), hydrocarbons (0.014), and noise (0.001) were significantly associated with increased blood pressure in motor vehicle testing officers. Conclusion: To mitigate the risks associated with pollutant exposure, it is recommended that workers engaged in motor vehicle testing wear personal protective equipment (PPE) and that working hours are limited.
RISK FACTORS OF HYPERTENSION IN PREGNANT WOMEN IN LABUHANBATU REGENCY: A CROSS−SECTIONAL STUDY: Faktor Risiko Hipertensi Pada Ibu Hamil di Kabupaten Labuhanbatu Hartono, Hartono; Manalu, Putranto; Janas, Dhyta Nurhasanah; Siagian, Masryna; Nadapdap, Marshall Jeremia
Jurnal Berkala Epidemiologi Vol. 13 No. 1 (2025): Jurnal Berkala Epidemiologi (Periodic Epidemiology Journal)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbe.V13I12025.85-92

Abstract

Background: Pregnant women with hypertension face elevated risks of complications, including preeclampsia and maternal mortality. Despite the increasing prevalence of gestational hypertension and its associated burdens, limited research—particularly at the local level—hinders effective prevention and management strategies. Purpose: This research aimed to investigate the risk factors associated with hypertension in pregnant women in Labuhan Batu Regency. Methods: This cross-sectional study involved 80 pregnant women from Labuhanbatu Regency, North Sumatra, Indonesia. Data on obesity, age, physical activity, and secondhand smoke exposure were collected through measurements and questionnaires. Obesity was assessed using mid-upper arm circumference (MUAC), while other variables were determined through interviews. Data were analyzed descriptively, and Fisher’s exact test was employed to compare risk factors between hypertensive and non-hypertensive pregnant women. Results: Obesity (p=0.29) and age (p=0.84) were not significantly associated with hypertension. However, pregnant women with light physical activity had a lower risk of hypertension compared to those with heavy physical activity (p=0.02). There was no significant association between exposure to cigarette smoke and hypertension (p=0.20). Conclusion: The findings suggest that light physical activity might be protective against hypertension during pregnancy among homemakers in Labuhanbatu regency.