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A case report of a mucocele Pulungan, Ica Yulianti
Jurnal Prima Medika Sains Vol. 5 No. 2 (2023): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i2.4465

Abstract

Frontal sinus mucoceles can present with a multitude of symptoms including ophthalmic disturbances. In benign conditions, they tend to expand by eroding the surrounding bony walls that displace and destroy structures through pressure and bony resorption. It becomes inflamed and filled with pus (pyocele) or a combination of both (mucopyocele). Due to its expansile nature, mucocele is important for diagnosis. Frontal mucoceles are benign and curable. Early recognition and management are important, as they can cause local, orbital, or intracranial complications. The purpose of this paper is to report a case of mucocele and emphasize the importance of radiological imaging, especially CT-Scan and MRI, in supporting the diagnosis of frontal sinus mucocele, detecting invasive processes to surrounding tissues and their extension to the intraorbita/intracranial, planning before surgery/biopsy, and evaluating the results of therapy.
The effect of betel nut extract on melanin pigment levels in rats' skin exposed to Ultraviolet B radiation Putri, Aisy; Pulungan, Ica Yulianti; Napitupulu, Olivia Des Vinca Albahana
Jurnal Prima Medika Sains Vol. 6 No. 1 (2024): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i1.5454

Abstract

This study aims to analyze the effect of areca nut extract on the amount of melanin pigment in the skin of Wistar rats exposed to ultraviolet-B light. The research method used was post-test with control group design. The total sample of white rats used was 20 rats, which were divided into 4 groups with each group consisting of 5 rats. The cream preparation was made using cold cream base. The rats were then exposed to UVB with a certain intensity for 5 days, characterized by erythema as a result of UVB absorption into the epidermis. Each group of treated rats received base cream, 10% areca nut extract cream, and 15% areca nut extract cream topically for 14 days before termination on day 15. The collected data were then tabulated and analyzed. To determine significant differences or influences between the test groups, analysis was carried out with t-test or Independent Samples T-Test approach at 95% confidence level (p < 0.05). The results of the analysis showed that the administration of areca nut extract was effective in reducing the amount of melanin pigment in the skin of Wistar rats exposed to Ultraviolet-B light. From histopathological observations, the administration of areca nut extract with a concentration of 15% is effective in removing or fading melanin pigments in the skin exposed to Ultraviolet-B light and the results of damaged skin melanin pigments appear in the epidermis of rat skin barely visible grain.
Anatomical variation findings of the paranasal sinuses based on CT scans in rhinosinusitis Thelim, Adeline; Pulungan, Ica Yulianti; Nasution, Ikhwanul Hakim; Rahmi, Clairine Altin Nur
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5817

Abstract

Rhinosinusitis is an inflammation of the paranasal sinuses and nasal mucosa that occurs due to bacterial, viral, fungal infections, allergens, or autoimmune conditions with signs and symptoms such as nasal congestion, runny nose, facial pain, and decreased olfactory ability, with causes such as host factors that are divided into systemic and local (such as anatomical abnormalities) as well as environmental factors such as viral or bacterial infections and allergen exposure. Anatomical variations in the sinonasal area can cause impaired drainage and ventilation to obstruction of the osteomeatal complex which ultimately causes and even exacerbates inflammation of the sinus mucosa, examples of anatomical variations such as septal deviation, agger nasi cells, concha bullosa, haller cells, onodi cells, and others, with the radiological modality widely used is CT - Scan. This study aimed to identify anatomical variations in rhinosinusitis cases based on CT scan examination results. This study is descriptive and uses a total sampling technique. A total of 53 samples were taken, with rhinosinusitis as the main diagnosis. Subsequently, a frequency distribution test was conducted. It was found that 45 samples had no anatomical variation and eight samples had anatomical variations in the form of septal deviation. The results showed that the anatomical variation found in rhinosinusitis patients at RSUD Dr. Pirngadi had a septal deviation of as many as eight samples (15.1%).
Radiographic evaluation of pulmonary tuberculosis: A comparative study of pre- and post-treatment chest X-rays at Royal Prima Hospital Rahmi, Clairine Altin Nur; Pulungan, Ica Yulianti; Nasution, Ikhwanul Hakim; Thelim, Adeline
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5869

Abstract

Pulmonary tuberculosis (TB) is a significant global health concern. Chest radiography is an essential tool for the diagnosis and monitoring of TB treatment. This retrospective cohort study aimed to analyze changes in chest radiographic findings among TB patients before and after treatment at Royal Prima Hospital. The study included 30 patients with TB who underwent repeated chest radiography between May 2023 and May 2024. Patient data were collected from the medical records. Descriptive analysis and the chi-square test were used to compare changes in radiographic findings between the treatment and non-treatment groups. Of the 30 patients, 15 (50%) showed positive changes on post-treatment radiographs, while the remaining 15 (50%) did not. The Chi-Square test revealed a significant difference (P < 0.05) between the two groups. Patients who received treatment had four-fold higher odds of experiencing radiographic changes than those who did not. These findings align with those of previous research demonstrating the efficacy of TB treatment in the repair of lung damage. Positive changes in post-treatment radiographs indicated that the treatment effectively suppressed Mycobacterium tuberculosis growth and facilitated lung tissue repair. Pulmonary TB treatment exerts a significant impact on changes in chest radiographic findings. This study underscores the importance of adequate TB treatment to achieve cure and prevent complications.
The correlation between thoracic radiographic findings in pulmonary tuberculosis and type 2 diabetes mellitus Pinem, Della Terulin; Nasution, Ikhwanul Hakim; Pulungan, Ica Yulianti
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6641

Abstract

Tuberculosis (TB), specifically pulmonary tuberculosis, is a contagious chronic infectious disease caused by Mycobacterium tuberculosis. Type 2 diabetes mellitus (T2DM) is a significant comorbidity that influences the clinical presentation of TB. Patients with pulmonary TB and T2DM exhibit a more severe clinical profile and a broader range of symptoms compared to those with PTB alone. Radiologically, TB-T2DM patients often present with more extensive, multilobular lesions and a higher incidence of cavitation. This study aimed to determine the association between the characteristics of chest X-ray findings in patients with pulmonary TB complicated by T2DM and those without T2DM at Royal Prima General Hospital, Medan. This research employed a quantitative methodology with a cross-sectional design. The sample comprised 50 medical records of pulmonary TB patients with T2DM and 50 medical records of pulmonary TB patients without T2DM. Data analysis involved univariate and bivariate statistical methods. The results indicated that the extent of lesions observed on chest X-rays in patients with pulmonary TB patients with T2DM, as well as those without T2DM, varied from minimal to moderate to extensive. The types of lesions identified included infiltrates, infiltrates with fibrosis, and fibrosis. No significant association was found between the extent of lesions or the type of lesions in pulmonary TB patients with T2DM and those without T2DM. The most prevalent lesion extent was moderate, and the most common lesion type was infiltrates with fibrosis.
Association of perirenal fat thickness, abdominal subcutaneous fat thickness and renal sinus fat diameter with hepatic steatosis Ernes, Audrina; Ginting, Chrismis Novalinda; Pulungan, Ica Yulianti
Jurnal Prima Medika Sains Vol. 7 No. 1 (2025): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v7i1.6758

Abstract

Hepatic steatosis (HS), characterized by the abnormal accumulation of triglycerides within hepatocytes, is a prevalent pathological condition. However, its detection rate often underestimates its true prevalence, particularly when assessed using abdominal computed tomography (CT) scans. This quantitative cross-sectional study, conducted from September 2024 to February 2025 at Royal Prima Hospital, aimed to investigate the associations of perirenal fat thickness (PrFT), abdominal subcutaneous fat thickness (ASFT), and renal sinus fat diameter (RSFD) with HS. A non-probability sampling method was utilized, and a total of 272 non-contrast abdominal CT scans were analyzed. Statistical analyses were performed using SPSS software. HS was defined as an average hepatic parenchymal Hounsfield Unit (HU) value at least 10 HU lower than that of the spleen, with an absolute hepatic HU attenuation of less than 40. The grading of HS was determined according to the CT liver-spleen (L-S) ratio: mild (0.7 < CT L-S < 1.0), moderate (0.5 < CT L-S < 0.7), and severe (CT L-S < 0.5). The results demonstrated a significant association between the mean right-left PrFT and the presence of HS (p = 0.007), suggesting that perirenal fat may contribute to the development of HS. In contrast, neither the mean right-left RSFD nor the ASFT showed a significant association with HS presence (p = 0.056 and p = 0.904, respectively). Furthermore, none of the fat measurements (PrFT, ASFT, and RSFD) were significantly associated with the grading of hepatic steatosis (p = 0.800, 0.288, and 0.996, respectively). These findings underscore the potential utility of PrFT as a non-invasive indicator for HS diagnosis. The study also highlights the importance of quantitative measurements, such as hepatic and splenic HU values and CT L-S ratios, for the accurate diagnosis of HS, as visual assessment alone may be insufficient.
Factors associated with nephrolithiasis at Royal Prima General Hospital Suryamin, Ricky; Pulungan, Ica Yulianti
Jurnal Prima Medika Sains Vol. 7 No. 1 (2025): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v7i1.6770

Abstract

The high incidence of kidney stones, or nephrolithiasis, at Royal Prima General Hospital in Medan, affecting 234 patients, constitutes a significant problem requiring resolution. The varied nature of nephrolithiasis presentations observed is attributable to numerous influencing factors. Potential causes of kidney stones include inadequate fluid intake, excessive or insufficient physical activity, obesity, high salt consumption, and other unhealthy behaviours. Furthermore, underlying medical conditions such as diabetes, obesity, and hypertension can elevate the risk of kidney stone formation. This research aimed to analyse the factors associated with nephrolithiasis at Royal Prima General Hospital in Medan. This study employed an observational analytical design with a retrospective approach. The study population comprised the medical records of 234 patients diagnosed with nephrolithiasis who sought treatment at Royal Prima General Hospital in Medan between August 2023 and August 2024. Total sampling was utilised, resulting in a sample size of 234. Data analysis involved univariate, bivariate, and multivariate methods. The results revealed that the majority of patients were aged 46-60 years (n=99, 42.3%) and were male (n=147, 62.8%). Significant associations were found between blood pressure, body mass index (BMI), age, and nephrolithiasis at Royal Prima General Hospital in Medan. However, no significant association was observed between gender and nephrolithiasis. Age (X4) was identified as the variable most strongly associated with nephrolithiasis at Royal Prima General Hospital in Medan.
Anatomical variation findings of the paranasal sinuses based on CT scans in rhinosinusitis Thelim, Adeline; Pulungan, Ica Yulianti; Nasution, Ikhwanul Hakim; Rahmi, Clairine Altin Nur
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5817

Abstract

Rhinosinusitis is an inflammation of the paranasal sinuses and nasal mucosa that occurs due to bacterial, viral, fungal infections, allergens, or autoimmune conditions with signs and symptoms such as nasal congestion, runny nose, facial pain, and decreased olfactory ability, with causes such as host factors that are divided into systemic and local (such as anatomical abnormalities) as well as environmental factors such as viral or bacterial infections and allergen exposure. Anatomical variations in the sinonasal area can cause impaired drainage and ventilation to obstruction of the osteomeatal complex which ultimately causes and even exacerbates inflammation of the sinus mucosa, examples of anatomical variations such as septal deviation, agger nasi cells, concha bullosa, haller cells, onodi cells, and others, with the radiological modality widely used is CT - Scan. This study aimed to identify anatomical variations in rhinosinusitis cases based on CT scan examination results. This study is descriptive and uses a total sampling technique. A total of 53 samples were taken, with rhinosinusitis as the main diagnosis. Subsequently, a frequency distribution test was conducted. It was found that 45 samples had no anatomical variation and eight samples had anatomical variations in the form of septal deviation. The results showed that the anatomical variation found in rhinosinusitis patients at RSUD Dr. Pirngadi had a septal deviation of as many as eight samples (15.1%).
Radiographic evaluation of pulmonary tuberculosis: A comparative study of pre- and post-treatment chest X-rays at Royal Prima Hospital Rahmi, Clairine Altin Nur; Pulungan, Ica Yulianti; Nasution, Ikhwanul Hakim; Thelim, Adeline
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 2 (2024): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i2.5869

Abstract

Pulmonary tuberculosis (TB) is a significant global health concern. Chest radiography is an essential tool for the diagnosis and monitoring of TB treatment. This retrospective cohort study aimed to analyze changes in chest radiographic findings among TB patients before and after treatment at Royal Prima Hospital. The study included 30 patients with TB who underwent repeated chest radiography between May 2023 and May 2024. Patient data were collected from the medical records. Descriptive analysis and the chi-square test were used to compare changes in radiographic findings between the treatment and non-treatment groups. Of the 30 patients, 15 (50%) showed positive changes on post-treatment radiographs, while the remaining 15 (50%) did not. The Chi-Square test revealed a significant difference (P < 0.05) between the two groups. Patients who received treatment had four-fold higher odds of experiencing radiographic changes than those who did not. These findings align with those of previous research demonstrating the efficacy of TB treatment in the repair of lung damage. Positive changes in post-treatment radiographs indicated that the treatment effectively suppressed Mycobacterium tuberculosis growth and facilitated lung tissue repair. Pulmonary TB treatment exerts a significant impact on changes in chest radiographic findings. This study underscores the importance of adequate TB treatment to achieve cure and prevent complications.
The correlation between thoracic radiographic findings in pulmonary tuberculosis and type 2 diabetes mellitus Pinem, Della Terulin; Nasution, Ikhwanul Hakim; Pulungan, Ica Yulianti
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6641

Abstract

Tuberculosis (TB), specifically pulmonary tuberculosis, is a contagious chronic infectious disease caused by Mycobacterium tuberculosis. Type 2 diabetes mellitus (T2DM) is a significant comorbidity that influences the clinical presentation of TB. Patients with pulmonary TB and T2DM exhibit a more severe clinical profile and a broader range of symptoms compared to those with PTB alone. Radiologically, TB-T2DM patients often present with more extensive, multilobular lesions and a higher incidence of cavitation. This study aimed to determine the association between the characteristics of chest X-ray findings in patients with pulmonary TB complicated by T2DM and those without T2DM at Royal Prima General Hospital, Medan. This research employed a quantitative methodology with a cross-sectional design. The sample comprised 50 medical records of pulmonary TB patients with T2DM and 50 medical records of pulmonary TB patients without T2DM. Data analysis involved univariate and bivariate statistical methods. The results indicated that the extent of lesions observed on chest X-rays in patients with pulmonary TB patients with T2DM, as well as those without T2DM, varied from minimal to moderate to extensive. The types of lesions identified included infiltrates, infiltrates with fibrosis, and fibrosis. No significant association was found between the extent of lesions or the type of lesions in pulmonary TB patients with T2DM and those without T2DM. The most prevalent lesion extent was moderate, and the most common lesion type was infiltrates with fibrosis.