Garuda - Garba Rujukan Digital

Penguatan Usaha Mandiri Diversifikasi Produk Jahe melalui Penyuluhan Pemilihan Kemasan Pemasaran Digital dan Perizinan Produk Setiawan, Vendra; Krisnawan, Alfian Hendra; Indarini, Indarini
Amalee: Indonesian Journal of Community Research and Engagement Vol 4 No 1 (2023): Amalee: Indonesian Journal of Community Research and Engagement
Publisher : LP2M INSURI Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/amalee.v4i1.2624

To survive the Covid-19 epidemic, businesses must employ innovative and important methods, one of which is functional food diversification for product expansion and higher selling value. However, some beginner entrepreneurs still do not understand this strategy, which causes the business to not develop, including what is experienced by partners. The goal of this community service project is to expand partners' knowledge of the marketing of diverse functional food products made from ginger, which was previously done in product production training. Marketing knowledge was provided through counseling methods related to digital marketing, packaging selection, and product licensing. The partners of this activity are the PKK group of RW 06 Rungkut Lor, Rungkut District, Surabaya. Participatory Action Research (PAR) with a counseling mechanism is the community service strategy adopted. Evaluation of increased knowledge using the pretest and posttest methods. The questions' components include the marketing process, marketing mix, digital marketing, general understanding of product licensing, and information related to NIB, PIRT permits, halal certificates, and BPOM food permits. According to the evaluation findings, there was a 9.59% gain in expertise in digital marketing outreach efforts and a 33.33% rise in product licensing outreach activities. It is envisaged that this increase in learning would aid in the resolution of partner product marketing issues and boost partner economic welfare.

Empowering Future Pharmacists in Chemistry Analysis of Nutraceuticals Setiawan, Vendra; Risthanti, Reine Risa; Makayasa, Citra Hayu; Alkindi, Fawandi Fuad; Cahyani, Ayu Eprilita Fitri Ika; Makhnunah, Ninis
Amalee: Indonesian Journal of Community Research and Engagement Vol 5 No 2 (2024): Amalee: Indonesian Journal of Community Research and Engagement
Publisher : LP2M INSURI Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/amalee.v5i2.5258

The community service aims to empower future pharmacists in East Java, Indonesia, by enhancing their understanding of nutraceuticals through chemistry analysis. Students gain essential skills for their academic pursuits through practical training in chromatography analysis and antioxidant activity measurements. The service equips students with practical skills in analyzing nutraceuticals, preparing them for further pharmacy studies. A training program was carried out for 88 SMA and SMK Farmasi students using Participatory Action Research (PAR). The main subjects covered were analysis using thin-layer chromatography, evaluation of functional groups in polyphenols, and assessment of antioxidant effectiveness. Pharmacy lecturers facilitated the program, guiding participants in practical competencies. The outcomes were successful, with a better understanding of nutraceuticals and valuable analytical skills gained. The significance of practical training and educational interventions in preparing students for advanced pharmacy studies is emphasized by this service.

Rapid screening analysis of antioxidant activities in green tea products using DPPH and FRAP Setiawan, Vendra; Phangestu, Sherlly; Soetikno, Agatha Grace; Arianti, Angelina; Kohar, Indrajati
Pharmaceutical Journal of Indonesia Vol. 7 No. 1 (2021)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2021.007.01.2

Free radicals are formed inside and outside the body. Free radicals inside the body can be created in the cell compartments. The reactions are complex through the initiation, propagation, and termination stages. On the other hand, free radicals in the outer body can be formed from pollutions and environmental damage action.Â Excessive free radicals cause oxidative stress and use destructive cellular to affect health conditions. Antioxidants are known as essential agents in biological systems against diseases triggered by free radicals. One of the many antioxidants found in tea plants (Camellia sinensis) is polyphenols. A colorimetry method was employed to evaluate the dominant antioxidant compound of the total phenolic and flavonoid content in two selected tea products. The total phenolic content was determined by utilizing the Folin-Ciocalteu reagent. In addition, an aluminum colorimetric assay is applied to assess flavonoid content. Rapid screening of antioxidant activity using a spectrophotometric method is employed to determine IC50 values of tea extracts utilizing DPPH and FRAP. The FRAP method showed more sensitivity in determining antioxidant activities with the feasibility of working in low analyte concentrations than the DPPH method. The high total phenolic and flavonoid contents found in this experiment are in line with low IC50 values. It was also found out that brewed green tea has lower total phenol content than green tea bags.

Rapid screening analysis of antioxidant activities in green tea products using DPPH and FRAP Setiawan, Vendra; Phangestu, Sherlly; Soetikno, Agatha Grace; Arianti, Angelina; Kohar, Indrajati
Pharmaceutical Journal of Indonesia Vol. 7 No. 1 (2021)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2021.007.01.2

Free radicals are formed inside and outside the body. Free radicals inside the body can be created in the cell compartments. The reactions are complex through the initiation, propagation, and termination stages. On the other hand, free radicals in the outer body can be formed from pollutions and environmental damage action.Â Excessive free radicals cause oxidative stress and use destructive cellular to affect health conditions. Antioxidants are known as essential agents in biological systems against diseases triggered by free radicals. One of the many antioxidants found in tea plants (Camellia sinensis) is polyphenols. A colorimetry method was employed to evaluate the dominant antioxidant compound of the total phenolic and flavonoid content in two selected tea products. The total phenolic content was determined by utilizing the Folin-Ciocalteu reagent. In addition, an aluminum colorimetric assay is applied to assess flavonoid content. Rapid screening of antioxidant activity using a spectrophotometric method is employed to determine IC50 values of tea extracts utilizing DPPH and FRAP. The FRAP method showed more sensitivity in determining antioxidant activities with the feasibility of working in low analyte concentrations than the DPPH method. The high total phenolic and flavonoid contents found in this experiment are in line with low IC50 values. It was also found out that brewed green tea has lower total phenol content than green tea bags.

A Review of Fungal-Derived Natural Dyes: Chemical Diversity and Multifaceted Health Benefits Budipramana, Krisyanti; Setiawan, Vendra; Ratih, Ratih; Budi Pramana, Yanatra
Jurnal Tumbuhan Obat Indonesia Vol. 17 No. 2 (2024): December 2024
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31002/jtoi.v17i2.1047

Various industrial sectors, from food and drug production to textiles, have widely used pigments or dyes as coloring agents. Generally, we can distinguish between two types of coloring agents: synthetic and natural. Currently, the use of synthetic colorings is a topic of debate due to their potential health risks, toxicity, and environmental pollution. This prompts a deeper exploration of natural resources as a more secure substitute for coloring agents. Plants, animals, microbes, and fungi can all provide natural coloring agents. Besides animals and microbes, some challenges in developing plants as major sources of natural coloring agents include variations in production or harvest times, strongly influenced by season, weather, and the intensity of sunlight. These factors influence not only the stability of the produced color but also its physicochemical properties, such as solubility and pH. Moreover, overexploitation of plants has an impact on ecosystem imbalances and leads to extinction. Among natural resources, pigments or dyes from fungi have shown their potential to address these challenges. This review focuses on the potential of various microfungi that produce natural dyes, especially from Monascaceae, Trichocomaceae, and Nectriaceae, as well as the classification based on their chemical structure. Furthermore, we describe their diverse biological impacts as antioxidants, antibiotics, antidiabetics, anticancer agents, and anti-cholesterol agents, along with their health advantages.

A Review of Fungal-Derived Natural Dyes: Chemical Diversity and Multifaceted Health Benefits Budipramana, Krisyanti; Setiawan, Vendra; Ratih, Ratih; Budi Pramana, Yanatra
Jurnal Tumbuhan Obat Indonesia Vol. 17 No. 2 (2024): December 2024
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31002/jtoi.v17i2.1047

Various industrial sectors, from food and drug production to textiles, have widely used pigments or dyes as coloring agents. Generally, we can distinguish between two types of coloring agents: synthetic and natural. Currently, the use of synthetic colorings is a topic of debate due to their potential health risks, toxicity, and environmental pollution. This prompts a deeper exploration of natural resources as a more secure substitute for coloring agents. Plants, animals, microbes, and fungi can all provide natural coloring agents. Besides animals and microbes, some challenges in developing plants as major sources of natural coloring agents include variations in production or harvest times, strongly influenced by season, weather, and the intensity of sunlight. These factors influence not only the stability of the produced color but also its physicochemical properties, such as solubility and pH. Moreover, overexploitation of plants has an impact on ecosystem imbalances and leads to extinction. Among natural resources, pigments or dyes from fungi have shown their potential to address these challenges. This review focuses on the potential of various microfungi that produce natural dyes, especially from Monascaceae, Trichocomaceae, and Nectriaceae, as well as the classification based on their chemical structure. Furthermore, we describe their diverse biological impacts as antioxidants, antibiotics, antidiabetics, anticancer agents, and anti-cholesterol agents, along with their health advantages.

Unlocking Kudu-Laos: Transforming Indonesia's Ethnic Herbal Drink with SMEs Development Support Setiawan, Vendra; Krisnawan, Alfian Hendra; Nugroho, JL Eko; Wahyudi, Eko Setyo; Alang, Cindy Anastasia; Simamora, Monica Celia
Amalee: Indonesian Journal of Community Research and Engagement Vol. 6 No. 1 (2025): Amalee: Indonesian Journal of Community Research and Engagement
Publisher : LP2M INSURI Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/amalee.v6i1.6199

This community service set out to improve the sustainability of Mr. Lamiran's Jamu Kudu-Laos SME through improved product quality, diversification, and marketing strategies. This study uses the Participatory Action Research (PAR) method to address key challenges by training on hygiene and measuring tools for consistent production, developing powdered jamu to extend shelf life, and redesigning packaging for better market appeal. An Increase in understanding of product diversification showed a 50% increase and a 16.7% increase in production techniques. Interestingly, hygiene practices and the use of measuring instruments were consistently applied. 30% of sales increase within three months of the training further demonstrated the program's impact. SWOT analysis highlighted product diversification as a key strength, while low public trust in herbal products remains challenging. Further research on evidence-based marketing, such as antioxidant activity testing, is recommended to increase consumer confidence. The finding indicates that community service supports the sustainability of Mr. Lamiran’s Jamu Kudu-Laos SME

Juvenile Murderers: Is It the Impact of Dark Triad Personality or Lead Poisoning? A Comparative Study Rahayu, Yusti Probowati; Setiawan, Vendra; Manafe, Rizky Pradita; Indrajati Kohar
Journal of Educational, Health and Community Psychology Vol 14 No 3 SEPTEMBER 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jehcp.vi.31016

This study contributes by integrating psychological and pharmacological perspectives in understanding juvenile murderers. This is a comparative study that compares DTP and Pb between juvenile murderers and non-criminal juveniles. The participants were 7 juvenile murderers and 7 non-criminal juveniles. Inductively coupled plasma optical emission spectroscopy was used to examine Pb levels in hair. A modified Paulhus and William DTP questionnaire was applied to all participants. Qualitative data used interview and drawing test on juvenile murderers. Quantitative data on murderous and non-criminal juveniles for DTP used T Test and Pb were analyzed with the Mann-Whitney U test. Correlation between DTP and Pb used Pearson Correlation. Qualitative analyzed used thematic content analysis. Results revealed that there are has significant differences on Pb between JM and NCM. Pb levels in juvenile murderers were higher than those in noncriminal ones. There is no difference between juvenile murderers and noncriminal ones, according to DTP. However, descriptive statistics revealed that adolescent murderers typically had higher DTP than noncriminal ones. Based on the structural interview and psychological drawing test, juvenile murderers tend to have DTP characteristics. Spearman correlation showed that there was no correlation between Pb and DTP noncriminal adolescents. Further research is needed with more precise and comprehensive methods to find out the causes of teenagers committing murder, one of them is qualitative approach. Integration with pharmaceuticals remains necessary because juvenile murder cannot be explained solely by a psychological approach.

Empowering Future Pharmacists in Chemistry Analysis of Nutraceuticals Setiawan, Vendra; Risthanti, Reine Risa; Makayasa, Citra Hayu; Alkindi, Fawandi Fuad; Cahyani, Ayu Eprilita Fitri Ika; Makhnunah, Ninis
Amalee: Indonesian Journal of Community Research and Engagement Vol. 5 No. 2 (2024): Amalee: Indonesian Journal of Community Research and Engagement
Publisher : LP2M INSURI Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37680/amalee.v5i2.5258

The community service aims to empower future pharmacists in East Java, Indonesia, by enhancing their understanding of nutraceuticals through chemistry analysis. Students gain essential skills for their academic pursuits through practical training in chromatography analysis and antioxidant activity measurements. The service equips students with practical skills in analyzing nutraceuticals, preparing them for further pharmacy studies. A training program was carried out for 88 SMA and SMK Farmasi students using Participatory Action Research (PAR). The main subjects covered were analysis using thin-layer chromatography, evaluation of functional groups in polyphenols, and assessment of antioxidant effectiveness. Pharmacy lecturers facilitated the program, guiding participants in practical competencies. The outcomes were successful, with a better understanding of nutraceuticals and valuable analytical skills gained. The significance of practical training and educational interventions in preparing students for advanced pharmacy studies is emphasized by this service.

The Antibacterial Activities of Piper betle and Allium cepa Extracts Against Staphylococcus aureus Setiawan, Vendra; Triono, Nathanel; Agustina, Astrid Karindra; Moira, Lovely Anastasia; Biutifasari, Verna; Budipramana, Krisyanti
Jurnal Penelitian Pendidikan IPA Vol 11 No 9 (2025): September: In Progress
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i9.10850

Indonesia rich in biodiversity, both animals and plants. This is known as ethnobotany. Local people learn to use natural herbs to meet their daily needs, and some commonly used herbs are Piper betle (betel leaf) and Allium cepa (red onion). They often use P. betle or A. cepa to cure various skin infections, one of which is furuncles. This study aimed to explore ethanol extracts of P. betle, A. cepa, and their combination against Staphylococcus aureus, the main bacterial cause of furuncles, using petri dish. The inhibition zones in petri dishes were measured using a caliper to evaluate the antibacterial efficacy. Each sample was tested with 3 replicates and kanamycin was used as positive control. The P. betle extract exhibited the strongest inhibitory effect with an inhibition zone of 17.70 ± 0.30 mm, followed by P. betle and A. cepa with ratio 1:1 produced an inhibition zone of 15.63 ± 0.58 mm. The ethanol extract of A. cepa showed the lowest inhibition zone only 14.38 ± 0.35 mm and this inhibition zone was similar to that of kanamycin as positive control.

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