Article Per Year (5 Year)
p-Index From 2020 - 2025
1.006
P-Index
This Author published in this journals
All Journal Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Health Sains International Journal of Advanced Health Science and Technology Jurnal Info Kesehatan Jurnal Teknokes
Simanjuntak, James Perdinan
Unknown Affiliation
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 5 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 5 Documents
Search

 1 
Study on the relationship between Vitamin D deficiency and Leukocyte Ratio in Multidrug Resistant Tuberculosis patients Sitanggang, Fardiah Tilawati; Simanjuntak, James Perdinan; Siti Sakdiah
International Journal of Advanced Health Science and Technology Vol. 3 No. 6 (2023): December
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijahst.v3i6.300

Abstract

Tuberculosis (TB) remains an important health problem in Indonesia,the problems more complex with phenomenon of multi-drug resistance Tuberculosis (MDR) which cause worse prognosis, long treatment,high risk of transmission to other and side effect of treatment. Vitamin D plays a role in non specific and specific immune responses in Mycobacterium tuberculosis (M.tb) infection. Vitamin D have a role in hematopoiesis and affects the early development of monocytes and granulocytes. M.tb infection causes changer in the ratio of neutrophil cells, lymphocytes and monocytes. Changes in the ratio reflect an increase or decrease of effective immune response. Using a case control design, this study will evaluate the correlation between vitamin D, leukocyte ratio and MDR-TB patients among MDR-TB patient cases and TB patient controls. Independent variable in this study were vitamin D levels, leukocyte ratios consisting of NLR, MLR, NMLR, and clinical status of respondents were the dependent variable. The result of this study found that vitamin D levels of TB patients all showed values ​​that were within range of in the insufficiency and deficiency categories. From this result TB patients must coverIn addition, the NLR and NMLR parameters were able to show that immune status problems were mainly found in the MDR-TB patients
Comparison of Several Types of Plasma as Media in the Germ Tube Test for Identification of Candida albicans Hidayati, Yunia; Asnaily, Asnaily; Jumaisal, Akhirul; Simanjuntak, James Perdinan
Jurnal Teknokes Vol. 16 No. 2 (2023): June
Publisher : Jurusan Teknik Elektromedik, Politeknik Kesehatan Kemenkes Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Candida albicans is a commensal on the oral mucosal surfaces of healthy individuals but can be pathogenic in immunocompromised individuals. The germ tube test is an inexpensive, faster, and easier method used to identify and differentiate it from other yeast species. Generally, the test is carried out using serum as the medium. Plasma overall has the same characteristics as serum and differs only in the content of clotting factors. In addition, plasma is easier to obtain than serum in most healthcare services. This study aims to demonstrate three types of plasma as alternative media for germ tube tests. CPDA (Citrate Phosphate Dextrose Adenine), EDTA (Ethylenediaminetetraacetic), and Sodium Citrate plasma were compared to serum in producing of germ tubes. Each plasma and serum was tested in five repetitions. The experimental method was carried out in Mycology Laboratory at the Health Polytechnic of Jambi. The data were observed based on the germ tube formation time and analyzed with a one-way ANOVA test. The average germ tube formation times observed in this study were 70 minutes (serum), 129 minutes (CPDA plasma), 164 minutes (EDTA plasma), and 146 minutes (Citrate plasma). The lengths were significantly different between serum and the three plasma (P>0.05). Nevertheless, CPDA plasma showed the average time which is at the minimum incubation time limit according to the standard protocol of the test. The CPDA plasma was faster than other plasma in the formating time of the germination. Therefore, CPDA plasma can be recommended as a substitute for serum in the germ tube test for it was easier to obtain, and considered safer to use.
Pesticide Exposure and Increased Liver Enzyme Activity among Suburban Horticultural Dahlan, Ahmad; Simanjuntak, James Perdinan; Mustopa, Raden; Putri, Devi Oktarina; Amanda, Putrilia; Ratri, Adinda Cahyaning; Syathibi, Ahmad; Sabarudin, Sabarudin; Haflin, Haflin
JURNAL INFO KESEHATAN Vol 21 No 4 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss4.1183

Abstract

Horticultural farmers use chemicals such as pesticides to increase productivity and product quality. Exposure to pesticides can cause health problems, especially in the liver. A reference for evaluating liver function is blood test results for ALT, AST, ALP, and GGT activity. This study aimed to characterize the transaminase enzyme activity in horticultural farmers in the southern ring road area of Jambi City based on the risk factors associated with pesticide exposure. This study employed a cross-sectional study approach in conjunction with a descriptive method. Thirty-four participants were involved, and blood samples were obtained from each for analysis in a lab. A photometer was utilized in the Medical Laboratory Technology department at Health Polytechnic of Jambi to measure the activity of liver enzymes. This study found some respondents who experienced increased enzyme activity, namely ALT: 8 people (23.5%), AST: 3 people (8.8%), ALP: 1 person (2.9%), and GGT: 1 person (2.9%.). Based on the risk description observed, it was known that the intensity of pesticide exposure showed a significant increase only in ALT enzyme activity (p=0.0048), while adherence to mask-wearing increased ALT (p=0.0018) and GGT (p=0.0134). This study discovered that wearing a mask and the amount of pesticide exposure can increase enzyme activity, which may indicate liver impairment in the horticultural farmers under observation. Workers are expected to pay greater attention to workplace safety by wearing masks and applying pesticides in the recommended dosages.
Hitung Sel Eosinofil dan Imunoglobulin E Sebagai Penanda Biologis Penyakit Paru Obstruktif Kronis (PPOK) Fardiah Tilawati; Sakdiah, Siti; Simanjuntak, James Perdinan; Mustopa, Raden; Yuliandari, Neta
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (413.694 KB) | DOI: 10.36418/syntax-literate.v7i12.11374

Abstract

Peningkatan jumlah penderita Penyakit Paru Obstruktif Kronik (PPOK) sudah menjadi permasalahan kesehatan yang semakin mengkhawatirkan terutama dalam masyarakat di dunia saat ini. Peningkatan terutama terjadi di negara berkembang yang memiliki proporsi risiko utama, perokok, yang masih tinggi. Studi ini mengamati potensi parameter pemeriksaan laboratorium hitung sel eosinofil yang sederhana untuk menilai potensinya sebagai penanda kondisi perkembangan PPOK. Dengan desain case control hasil uji tersebut dianalisis dengan membandingkan antar subjek yang belum pernah didiagnosis menderita PPOK namun memiliki kebiasaan merokok yang merupakan faktor risiko utamanya dengan subjek bukan perokok. Pengujian hitung sel eosinofil terhadap spesimen darah dan saliva adalah parameter yang dapat diterapkan dalam analisis laboratorium klinik untuk diagnosis berbagai kondisi alergi. Namun dalam analisis rutin pengujian tersebut tidak dilakukan terhadap spesimen saliva (air liur. Pengujian dilakukan terhadap parameter hitung sel eosinofil dan keberadaan Imunoglobulin E (IgE), baik pada spesimen darah maupun saliva sebagai bahan yang akan dianalisis. Hasil penelitian mendapatkan jumlah eosinofil dan IgE pada saliva dan darah lebih tinggi pada pasien PPOK dibandingkan dengan kontrol (Non PPOK perokok dan Non PPOK non perokok), sedangkan eosinofil dan IgE pada saliva dan darah juga lebih tinggi pada kelompok kontrol perokok dibandingkan dengan non perokok dengan perbedaan yang signifikan. Selain itu parameter jumlah eosinofil pada saliva serta IgE pada saliva dapat menggambarkan deteksi dini dari perjalanan penyakit PPOK dengan ditunjukkan dengan korelasi yang kuat antar parameter.
Survey of Inflammatory Biomarkers in Blood and Sputum in Pulmonary Tuberculosis Patients Simanjuntak, James Perdinan; Sakdiah, Siti; Sitanggang, Fardiah Tilawati; Maharani, Eva Ayu
Jurnal Health Sains Vol. 4 No. 10 (2023): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v4i10.1092

Abstract

Tuberculosis (TB) is still a global health problem that exists today. Various efforts to reduce the number of TB patients have been carried out ranging from detection efforts to treatment and prevention efforts. Many studies have been conducted previously to look at the detection potential of laboratory diagnoses in finding new cases of tuberculosis. Likewise, efforts to detect prognosis in the laboratory to monitor the development of the condition of TB patients. The development of inflammatory conditions in TB patients is important to accelerate the healing process of these patients. Inflammatory marker tests have been widely performed on several types of laboratory test parameters. CRP and LDH are types of testing that have potential as markers of inflammatory development in TB patients. However, proven tests generally use blood specimens, which are commonly used in laboratory analysis for these parameters. Meanwhile, the current research theme has also been directed at the use of other types of specimens that can show inflammatory conditions experienced by a person. Saliva is known to have potential as another alternative specimen that can be used for such purposes. Saliva is easily obtained and does not require invasive techniques such as needle invocation, so it is considered to have more advantages if it can be proven as a laboratory test specimen that can provide information that is as good and accurate as blood or serum. This study aimed to assess the potential of saliva as an alternative specimen for laboratory analysis with the aim of markers in the assessment of prognosis of TB patients. CRP examination and LDH enzyme activity were chosen in this study of serum and saliva specimens of TB subjects and controls. From this study, it is expected to be shown that saliva can be used as an alternative specimen in laboratory analysis for inflammatory marker tests on both parameters. The results obtained showed that the measurement of LDH activity and and CRP levels in saliva observed in this study proved to have good potential in predicting the presence of inflammation and cell damage experienced by TB subjects. LDH test results have a strong relationship between serum and saliva as laboratory test materials, even salivary LDH levels are higher than serum. While CRP, although saliva showed low levels, the correlation test carried out still showed a strong relationship between the results of the two types of specimens.
Co-Authors Ahmad Dahlan Amanda, Putrilia Asnaily, Asnaily Fardiah Tilawati Fardiah Tilawati Sitanggang Haflin, Haflin Hidayati, Yunia Jumaisal, Akhirul Maharani, Eva Ayu Mustopa, Raden Putri, Devi Oktarina Ratri, Adinda Cahyaning Sabarudin Sabarudin Sakdiah, Siti Siti Sakdiah Syathibi, Ahmad Yuliandari, Neta