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All Journal Jurnal Fitofarmaka Indonesia JFL : Jurnal Farmasi Lampung Indonesian Journal of Behavioral Studies Jurnal Farmasi Indonesia Jurnal Pengabdian Kepada Masyarakat Darma Saskara Journal of Public Health Indonesian
Suzana, Dona
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences Other

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UJI AKTIVITAS ANTIOKSIDAN MINUMAN SARI BUAH MARKISA “SEEOWRENS” SEBAGAI UPAYA PENGEMBANGAN DAN EVALUASI MANFAAT BAGI KONSUMEN DI KOTA DEPOK Masyithah, Lathvi; Nainggolan, Hotlina; Oktavilantika, Dina Melia; Suzana, Dona
Jurnal Pengabdian Kepada Masyarakat Darma Saskara Vol 5, No 1 (2025)
Publisher : Jurnal Pengabdian Kepada Masyarakat Darma Saskara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35760/abdimasug.2025.v5i1.14362

Abstract

Kegiatan pengabdian masyarakat ini bertujuan untuk menguji aktivitas antioksidan minuman sari buah markisa “Seeowrens” sebagai bagian dari upaya peningkatan kualitas produk dan nilai tambah bagi konsumen. Uji laboratorium dilakukan menggunakan metode DPPH (Diphenyl-1-Picrylhydrazyl) untuk mengukur kapasitas antioksidan dari produk teh markisa. Hasil menunjukkan bahwa minuman tersebut berada dalam kategori sedang berdasarkan nilai IC₅₀ yang diperoleh. Temuan ini tidak hanya memberikan validasi ilmiah terhadap manfaat kesehatan produk, tetapi juga mendukung strategi promosi dan pengembangan produk berbasis fitokimia lokal. Dengan demikian, kegiatan ini memberikan dampak positif baik bagi mitra UMKM maupun konsumen dalam memilih produk yang lebih sehat dan bernilai tambah.
USING PARE FRUIT (Momordica charantia L) AS AN ANTIDEPRESSANT AGENT USING THE FORCED SWIM TEST (FST) METHOD: PARE FRUIT (Momordica charantia L) AS AN ANTIDEPRESSANT AGENT USING THE FORCED SWIM TEST (FST) METHOD Suzana, Dona; Kencana, Ghista Kurnia
JFL : Jurnal Farmasi Lampung Vol. 14 No. 1 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v14i1.2419

Abstract

Depression is a serious psychological disorder that requires long-term therapy. The use of synthetic antidepressants such as fluoxetine often causes side effects and complex drug interactions, thus encouraging the search for herbal alternatives. This study evaluated the antidepressant activity of ethanol extract of bitter melon fruit (Momordica charantia L.) through the Forced Swim Test (FST) method in male Balb/c mice. Four treatment groups were used: negative control (aquadest), positive control (fluoxetine 120 mg/kgBB), comparative control (stelazine), and bitter melon extract (270 mg/kgBB). The results of the FST test showed that bitter melon extract significantly reduced the immobility time of mice (p = 0.005), equivalent to fluoxetine and stelazine. Phytochemical tests identified the presence of flavonoids, triterpenoids, alkaloids, saponins, and polyphenols, which are thought to contribute to antidepressant activity through increased monoamine levels and neuroprotective effects. The conclusion is that ethanol extract of bitter melon shows strong potential as an herbal antidepressant agent comparable to fluoxetine, as well as being feasible to be developed as a phytopharmaceutical for depression therapy. Keywords: bitter melon, antidepressant, Momordica charantia, Forced Swim Test, triterpenoids
Co-Authors Airlangga, Dean Zulmi Alida, Mufni Arianta, Harits Atika Caesaria, Polita Ayu cahyono, didik Febriyani, Ayu Handayanti, Isnani Harits Atika Ariyanta Hayuningsih, Sri Himawati, Ditiya HS, Ikhwan Irina Mildawani Kencana, Ghista Kurnia Masyithah, Lathvi Nainggolan, Hotlina Oktavilantika, Dina Melia Putra, Hendri Dwi Rachmi Ridho Rismiayati, Fitri Rismiyati, Fitri Windha Pagiu , Hayuti Yuningsih , Silvia Anita