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All Journal Jurnal Fitofarmaka Indonesia JSFK (Jurnal Sains Farmasi & Klinis) JFL : Jurnal Farmasi Lampung Indonesian Journal of Behavioral Studies Jurnal Katalisator Jurnal Farmasi Indonesia Jurnal Pengabdian Kepada Masyarakat Darma Saskara Journal of Public Health Indonesian
Suzana, Dona
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health Social Sciences Other

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UJI AKTIVITAS ANTIOKSIDAN MINUMAN SARI BUAH MARKISA “SEEOWRENS” SEBAGAI UPAYA PENGEMBANGAN DAN EVALUASI MANFAAT BAGI KONSUMEN DI KOTA DEPOK Masyithah, Lathvi; Nainggolan, Hotlina; Oktavilantika, Dina Melia; Suzana, Dona
Jurnal Pengabdian Kepada Masyarakat Darma Saskara Vol 5, No 1 (2025)
Publisher : Jurnal Pengabdian Kepada Masyarakat Darma Saskara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35760/abdimasug.2025.v5i1.14362

Abstract

Kegiatan pengabdian masyarakat ini bertujuan untuk menguji aktivitas antioksidan minuman sari buah markisa “Seeowrens” sebagai bagian dari upaya peningkatan kualitas produk dan nilai tambah bagi konsumen. Uji laboratorium dilakukan menggunakan metode DPPH (Diphenyl-1-Picrylhydrazyl) untuk mengukur kapasitas antioksidan dari produk teh markisa. Hasil menunjukkan bahwa minuman tersebut berada dalam kategori sedang berdasarkan nilai IC₅₀ yang diperoleh. Temuan ini tidak hanya memberikan validasi ilmiah terhadap manfaat kesehatan produk, tetapi juga mendukung strategi promosi dan pengembangan produk berbasis fitokimia lokal. Dengan demikian, kegiatan ini memberikan dampak positif baik bagi mitra UMKM maupun konsumen dalam memilih produk yang lebih sehat dan bernilai tambah.
USING PARE FRUIT (Momordica charantia L) AS AN ANTIDEPRESSANT AGENT USING THE FORCED SWIM TEST (FST) METHOD: PARE FRUIT (Momordica charantia L) AS AN ANTIDEPRESSANT AGENT USING THE FORCED SWIM TEST (FST) METHOD Suzana, Dona; Kencana, Ghista Kurnia
JFL : Jurnal Farmasi Lampung Vol. 14 No. 1 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v14i1.2419

Abstract

Depression is a serious psychological disorder that requires long-term therapy. The use of synthetic antidepressants such as fluoxetine often causes side effects and complex drug interactions, thus encouraging the search for herbal alternatives. This study evaluated the antidepressant activity of ethanol extract of bitter melon fruit (Momordica charantia L.) through the Forced Swim Test (FST) method in male Balb/c mice. Four treatment groups were used: negative control (aquadest), positive control (fluoxetine 120 mg/kgBB), comparative control (stelazine), and bitter melon extract (270 mg/kgBB). The results of the FST test showed that bitter melon extract significantly reduced the immobility time of mice (p = 0.005), equivalent to fluoxetine and stelazine. Phytochemical tests identified the presence of flavonoids, triterpenoids, alkaloids, saponins, and polyphenols, which are thought to contribute to antidepressant activity through increased monoamine levels and neuroprotective effects. The conclusion is that ethanol extract of bitter melon shows strong potential as an herbal antidepressant agent comparable to fluoxetine, as well as being feasible to be developed as a phytopharmaceutical for depression therapy. Keywords: bitter melon, antidepressant, Momordica charantia, Forced Swim Test, triterpenoids
EVALUATION OF ANTIBIOTIC USE FOR DIARRHEA THERAPY IN TODDLERS AT PUSKESMAS BEJI DEPOK CITY Masyithah, Lathvi; Rosmawati, Rosmawati; Suzana, Dona
JURNAL KATALISATOR Vol. 10 No. 2 (2025): Jurnal Katalisator, Volume 10 No 2 Oktober 2025
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v10i2.3452

Abstract

Acute diarrhea is diarrhea more than fourteen days and is generally caused by microbial infection. The principles management of acute diarrhea are rehydration, symptomatic therapy, and selective and rational antibiotic therapy. Previous study shown antibiotic prescriptions for diarrhea therapy are still quite high, a study at the Bangsal Puskesmas in Mojokerto Regency showed that 27% was inappropriate for the indication. The aim this study was to evaluate the rationality of using antibiotics for diarrhea in toddlers. This study is a descriptive study with retrospective data collection from the medical records of toddler diarrhea patients at the Puskesmas Beji in Depok City in 2021 who met the inclusion and exclusion criteria. The results of the study showed the use of antibiotics such as metronidazole, amoxicillin, and cotrimoxazole was the right choice because it was in accordance with the choice of antibiotic therapy for acute diarrhea with specific indications, however the results of the evaluation of antibiotic prescriptions were not appropriate indications there was still a high number 62,5% of antibiotic prescriptions for patients with non-specific acute diarrhea. Antibiotic prescriptions must be based on the bacteria causing the infection so it is very necessary to be supported by data from laboratory tests.
Formulation and Evaluation of Sunscreen Body Butter Preparation Containing Soursop Leaf Extract (Annona muricata L.) and Its Influence on Sun Protection Factor (SPF) Value Kholilah, Noor; Masyithah, Lathvi; Suzana, Dona
JSFK (Jurnal Sains Farmasi & Klinis) Vol 12 No 2 (2025): J Sains Farm Klin 12(2), August 2025
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.12.2.102-110.2025

Abstract

The leaf part of the soursop plant (Annona muricata L.) contains phenolic compounds, especially flavonoids and tannins, which have sunscreen potential due to the presence of chromophore groups. These groups have conjugated double bonds capable of absorbing ultraviolet rays, thus reducing their intensity on the skin. This study aims to formulate sunscreen body butter preparations from soursop leaf extract with good stability and to determine the effect of varying concentrations of soursop leaf extract on the SPF value of the preparations. Soursop leaf ethanol extract was obtained by maceration with 70% ethanol. Body butter was formulated due to its efficacy in preserving skin hydration, improving softness, and protecting against environmental stressors. SPF value measurements were conducted using spectrophotometric methods. The evaluation results of sunscreen body butter from formulas 1, 2, and 3 were sequentially light green, strong green, and dark green in color; with a typical weak extract odor, homogeneous, pH 7, and a spreadability of 6 - 6.5 cm. Stability testing with a cycling test showed that all three preparation formulas were stable. The SPF values of sunscreen body butter containing ethanol extract of soursop leaves for F1 extract 1% were 7.07, categorized as extra protection; F2 extract 2% was 10.51, categorized as maximum protection; and F3 extract 3% was categorized as ultra protection. The higher the concentration of extract in the preparation, the higher the SPF value it possesses
Co-Authors Airlangga, Dean Zulmi Alida, Mufni Arianta, Harits Atika Caesaria, Polita Ayu cahyono, didik Endrasti, Gresia Adriel Febriyani, Ayu Handayanti, Isnani Harits Atika Ariyanta Hayuningsih, Sri Himawati, Ditiya HS, Ikhwan Irina Mildawani Kencana, Ghista Kurnia Kholilah, Noor Masyithah, Lathvi Melina, Citra Nainggolan, Hotlina Ninia, Kriselda Evelyin Oktavilantika, Dina Melia Putra, Hendri Dwi Qothoni, Wildah Benigna Rachmi Ridho Rismiayati, Fitri Rismiyati, Fitri Rosmawati Rosmawati Windha Pagiu , Hayuti Yuningsih , Silvia Anita