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All Journal Jurnal Prima Medika Sains Jurnal Inovasi Pendidikan dan Sains
Lumbantobing, Christina J.R Esmaralda
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Health Professions Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Pengaruh variasi pemberian dosis aloksan terhadap angka kadar gula darah hewan coba Dachi, Virent Nifadila O.; Rayyan, Teuku Arif; Utami, Sherlinda Putri; Mutia, Rena; Akbar, Khainir; Lumbantobing, Christina J.R Esmaralda; Kunardi, Sidharta; Jansen, Jansen; Djuang, Michelle Hendriani
Jurnal Prima Medika Sains Vol. 4 No. 1 (2022): Juni
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v4i1.2460

Abstract

Diabetes merupakan penyakit long-term yang dapat terjadi ketika kadar gula dalam darah tinggi sehingga tidak dapat memproduksi zat insulin secara cukup atau insulin tidak dapat bekerja secara efektif. Diperkirakan akan meningkat di tahun 2030 menjadi 552 juta jiwa jika tidak mendapatkan penanganan yang baik. Aloksan merupakan penyebab sel-β pankreas mengalami nekrosis juga sering dipakai sebagai bahan eksperimental dalam topik diabetes dengan kasus yang bervariasi pada hewan seperti tikus, mencit, dan anjing. Studi ini bertujuan untuk menganalisis dan merangkum studi-studi terdahulu mengenai pengaruh variasi pemberian dosis aloksan terhadap angka kadar gula darah hewan coba.
Handgrip Strength as an Indicator of Quality of Life in Chronic Kidney Disease Patients Undergoing Hemodialysis Amalia, Tiara; Lumbantobing, Christina J.R Esmaralda; Chiuman, Linda; Rajagukguk, Samuel Joshua Hamonangan Tua
JURNAL INOVASI PENDIDIKAN DAN SAINS Vol 6 No 3 (2025): December
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Nahdlatul Wathan Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51673/jips.v6i3.2768

Abstract

Handgrip strength has been associated with various chronic diseases, length of hospitalization, cognitive decline, and even mortality. Hemodialysis administered to patients with chronic kidney disease affects their physical functioning, manifested as fatigue, mobility limitations, and a decline in the ability to perform daily activities. The goal of this study was to look at how hemodialysis patients at Rasyida Kidney Specialty Hospital Medan felt about their quality of life in relation to their grip strength. The research team used a cross-sectional analytical observational design to compile their findings. At Rasyida renal Hospital Medan, 52 patients with chronic renal disease who were receiving hemodialysis were included in the study. All participants had to meet the inclusion and exclusion criteria that were previously established. The research team used a handgrip dynamometer to measure grip strength, and the WHOQOL-BREF to assess quality of life. Processing of the data involved both bivariate and univariate analyses. Findings: There was a statistically significant correlation between age (p = 0.001) and both sex and quality of life (p = 0.003). Nevertheless, neither handgrip strength (p = 0.156), comorbidities (p = 0.618), nor the length of time on hemodialysis (p = 0.746) were significantly associated with quality of life. Conclusion: Physical strength as measured by handgrip, comorbid diabetes mellitus, and length of dialysis treatment do not seem to have a significant impact on quality of life among hemodialysis patients with chronic kidney disease. However, demographic characteristics, such as age and sex, do affect quality of life. Physical capacity as measured by handgrip strength is less important than demographic determinants in determining quality of life, according to these studies. Therefore, interventions aimed at improving quality of life are required, including social support and a care approach that focuses particularly on elderly patient groups rather than solely on physical aspects
Co-Authors AMALIA, TIARA Chiuman, Linda Dachi, Virent Nifadila O. Djuang, Michelle Hendriani Jansen, Jansen Khainir Akbar, Khainir Kunardi, Sidharta Mutia, Rena Rajagukguk, Samuel Joshua Hamonangan Tua Rayyan, Teuku Arif Utami, Sherlinda Putri