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Pengaruh variasi pemberian dosis aloksan terhadap angka kadar gula darah hewan coba Dachi, Virent Nifadila O.; Rayyan, Teuku Arif; Utami, Sherlinda Putri; Mutia, Rena; Akbar, Khainir; Lumbantobing, Christina J.R Esmaralda; Kunardi, Sidharta; Jansen, Jansen; Djuang, Michelle Hendriani
Jurnal Prima Medika Sains Vol. 4 No. 1 (2022): Juni
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v4i1.2460

Diabetes merupakan penyakit long-term yang dapat terjadi ketika kadar gula dalam darah tinggi sehingga tidak dapat memproduksi zat insulin secara cukup atau insulin tidak dapat bekerja secara efektif. Diperkirakan akan meningkat di tahun 2030 menjadi 552 juta jiwa jika tidak mendapatkan penanganan yang baik. Aloksan merupakan penyebab sel-β pankreas mengalami nekrosis juga sering dipakai sebagai bahan eksperimental dalam topik diabetes dengan kasus yang bervariasi pada hewan seperti tikus, mencit, dan anjing. Studi ini bertujuan untuk menganalisis dan merangkum studi-studi terdahulu mengenai pengaruh variasi pemberian dosis aloksan terhadap angka kadar gula darah hewan coba.

The relationship between diet and weight training with ideal body shape among members of Katamso Fitness Centre, Medan City Sebayang, Robby Gunawan; Polem, Fahmi; Siregar, Hesti Despita; Putri, Lenni Dianna; Kunardi, Sidharta; Fransisca, Silvia; Bestari, Welas; Tarigan, Antje Irmella; Janice, Janice; Arhamni, Ade; Kurniawan, Evan
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7436

Katamso Fitness Centre is a gym surrounded by individuals aiming for an ideal and healthy physique. Members typically join to address less-than-ideal body weight and seek weight training to achieve their desired body shape—transforming from thin to muscular, or from overweight to lean, while also burning calories for overall health and fitness. This study employed a Chi-Square statistical test using SPSS for Windows, with a significance level of α=0.05. This analysis aimed to examine the relationship between independent and dependent variables. The research findings from 86 respondents indicate that the majority, 57 (66.3%), had a more ideal body shape. For diet patterns, the majority, 66 (76.7%), reported "sufficient." Regarding weight training, most respondents, 54 (62.8%), engaged in a "moderate" level.The relationship between diet patterns and ideal body shape among Katamso Fitness Centre members in Medan City showed a P-value of α>0.05, leading to the acceptance of Ha as significant. Conversely, the relationship between weight training and ideal body shape among members of the fitness center in Medan City showed a P-value of α<0.05, also leading to the acceptance of Ha as significant.

The relationship between diet and weight training with ideal body shape among members of Katamso Fitness Centre, Medan City Sebayang, Robby Gunawan; Polem, Fahmi; Siregar, Hesti Despita; Putri, Lenni Dianna; Kunardi, Sidharta; Fransisca, Silvia; Bestari, Welas; Tarigan, Antje Irmella; Janice, Janice; Arhamni, Ade; Kurniawan, Evan
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7436

Katamso Fitness Centre is a gym surrounded by individuals aiming for an ideal and healthy physique. Members typically join to address less-than-ideal body weight and seek weight training to achieve their desired body shape—transforming from thin to muscular, or from overweight to lean, while also burning calories for overall health and fitness. This study employed a Chi-Square statistical test using SPSS for Windows, with a significance level of α=0.05. This analysis aimed to examine the relationship between independent and dependent variables. The research findings from 86 respondents indicate that the majority, 57 (66.3%), had a more ideal body shape. For diet patterns, the majority, 66 (76.7%), reported "sufficient." Regarding weight training, most respondents, 54 (62.8%), engaged in a "moderate" level.The relationship between diet patterns and ideal body shape among Katamso Fitness Centre members in Medan City showed a P-value of α>0.05, leading to the acceptance of Ha as significant. Conversely, the relationship between weight training and ideal body shape among members of the fitness center in Medan City showed a P-value of α<0.05, also leading to the acceptance of Ha as significant.

The association between smoking behaviour and degenerative diseases Simarmata, Gracia Imanuela; Hartono, Hartono; Sihotang, Widya Yanti; Tobing, Andrico Napolin Lumban; Dharma, Surya; Mylano, Tri Adi; Setiawan, Deni; Willano, Almira; Novianti, Desi; Suwanto, Denny; Haryadi, Haryadi; Mukhtar, Zulfikri; Kunardi, Sidharta; Reza, Faisal
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 2 (2025): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i2.7756

Degenerative diseases represent a leading global cause of death, imposing a substantial health burden, wherein behavioural factors such as smoking are posited to play a significant role. This study aimed to analyse the association between smoking behaviour and the incidence of various degenerative diseases through a systematic literature review. The methodology employed was a systematic literature review, with article searches conducted across Google Scholar, PubMed, and Scopus databases from May to June 2025. Inclusion criteria encompassed full-text articles in Indonesian or English, published between 2020 and 2025, focusing on the association between smoking and degenerative diseases (hypertension, diabetes, stroke, kidney failure, cancer). From 230 identified articles, 15 met the criteria and were analysed. The synthesis of results demonstrated a significant association between smoking behaviour and an increased risk of degenerative diseases. Active smokers exhibited a three-fold higher risk of hypertension (OR=3.445), a twelve-fold higher risk of type 2 diabetes mellitus (OR=12.747), and a greater risk of developing cancer (lung, breast, laryngeal), stroke, and chronic kidney disease (CKD). Exposure to secondhand smoke among passive smokers also increased the risk of breast cancer nearly fourfold (OR=3.778). Underlying mechanisms include oxidative damage, chronic inflammation, endothelial dysfunction, and metabolic dysregulation. It is concluded that smoking is a major modifiable risk factor for degenerative diseases. Strengthening tobacco control policies, intensive health education, and smoking cessation programmes are required as primary prevention strategies.

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