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Pengaruh variasi pemberian dosis aloksan terhadap angka kadar gula darah hewan coba Dachi, Virent Nifadila O.; Rayyan, Teuku Arif; Utami, Sherlinda Putri; Mutia, Rena; Akbar, Khainir; Lumbantobing, Christina J.R Esmaralda; Kunardi, Sidharta; Jansen, Jansen; Djuang, Michelle Hendriani
Jurnal Prima Medika Sains Vol. 4 No. 1 (2022): Juni
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v4i1.2460

Abstract

Diabetes merupakan penyakit long-term yang dapat terjadi ketika kadar gula dalam darah tinggi sehingga tidak dapat memproduksi zat insulin secara cukup atau insulin tidak dapat bekerja secara efektif. Diperkirakan akan meningkat di tahun 2030 menjadi 552 juta jiwa jika tidak mendapatkan penanganan yang baik. Aloksan merupakan penyebab sel-β pankreas mengalami nekrosis juga sering dipakai sebagai bahan eksperimental dalam topik diabetes dengan kasus yang bervariasi pada hewan seperti tikus, mencit, dan anjing. Studi ini bertujuan untuk menganalisis dan merangkum studi-studi terdahulu mengenai pengaruh variasi pemberian dosis aloksan terhadap angka kadar gula darah hewan coba.
The Effect of Swimming Aerobic Physical Exercise On White Rats (Rattus Novergicus) Of the Wistar Strain That Are Obese Altamira, Vita; Angie, Evelyn; Kunardi, Sidharta
International Journal of Health and Pharmaceutical (IJHP) Vol. 4 No. 3 (2024): August 2024
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v4i2.321

Abstract

Women are more likely to be obese and at risk of hypertension and coronary heart disease than men. Genetic factors influence it. Physical exercise can reduce obesity, especially on endothelial factors such as ET-1 and NO. This research explores the effect of swimming physical training on the expression of endothelin-1 and receptor-A in obese mouse models. This type of research is a true experiment carried out on 12 adult female Wistar rats (Rattus norvegicus) as research samples. The research procedures were carried out by caring for test animals, raising rats until they were obese, not giving treatment (control), physical training in the form of swimming exercises, and finally, examination of ET-1, ET-A, blood sugar levels, and total cholesterol levels. The data obtained was analyzed using SPSS. The research results of the normality test for the treatment group were more significant than 0.05 in the ET-1 examination of 0.315 and ET-A of 0.261. ET-1 levels were 92.5 pg/ml and ET-A levels were 62.5 pg/ml. Their blood sugar level was 167 mg/dL. The research concluded that in mouse tests, physical training was better for increasing ET-1 levels and reducing ET-A levels. Swimming and aerobics are better at lowering blood sugar levels.
The relationship between diet and weight training with ideal body shape among members of Katamso Fitness Centre, Medan City Sebayang, Robby Gunawan; Polem, Fahmi; Siregar, Hesti Despita; Putri, Lenni Dianna; Kunardi, Sidharta; Fransisca, Silvia; Bestari, Welas; Tarigan, Antje Irmella; Janice, Janice; Arhamni, Ade; Kurniawan, Evan
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7436

Abstract

Katamso Fitness Centre is a gym surrounded by individuals aiming for an ideal and healthy physique. Members typically join to address less-than-ideal body weight and seek weight training to achieve their desired body shape—transforming from thin to muscular, or from overweight to lean, while also burning calories for overall health and fitness. This study employed a Chi-Square statistical test using SPSS for Windows, with a significance level of α=0.05. This analysis aimed to examine the relationship between independent and dependent variables. The research findings from 86 respondents indicate that the majority, 57 (66.3%), had a more ideal body shape. For diet patterns, the majority, 66 (76.7%), reported "sufficient." Regarding weight training, most respondents, 54 (62.8%), engaged in a "moderate" level.The relationship between diet patterns and ideal body shape among Katamso Fitness Centre members in Medan City showed a P-value of α>0.05, leading to the acceptance of Ha as significant. Conversely, the relationship between weight training and ideal body shape among members of the fitness center in Medan City showed a P-value of α<0.05, also leading to the acceptance of Ha as significant.
The relationship between diet and weight training with ideal body shape among members of Katamso Fitness Centre, Medan City Sebayang, Robby Gunawan; Polem, Fahmi; Siregar, Hesti Despita; Putri, Lenni Dianna; Kunardi, Sidharta; Fransisca, Silvia; Bestari, Welas; Tarigan, Antje Irmella; Janice, Janice; Arhamni, Ade; Kurniawan, Evan
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7436

Abstract

Katamso Fitness Centre is a gym surrounded by individuals aiming for an ideal and healthy physique. Members typically join to address less-than-ideal body weight and seek weight training to achieve their desired body shape—transforming from thin to muscular, or from overweight to lean, while also burning calories for overall health and fitness. This study employed a Chi-Square statistical test using SPSS for Windows, with a significance level of α=0.05. This analysis aimed to examine the relationship between independent and dependent variables. The research findings from 86 respondents indicate that the majority, 57 (66.3%), had a more ideal body shape. For diet patterns, the majority, 66 (76.7%), reported "sufficient." Regarding weight training, most respondents, 54 (62.8%), engaged in a "moderate" level.The relationship between diet patterns and ideal body shape among Katamso Fitness Centre members in Medan City showed a P-value of α>0.05, leading to the acceptance of Ha as significant. Conversely, the relationship between weight training and ideal body shape among members of the fitness center in Medan City showed a P-value of α<0.05, also leading to the acceptance of Ha as significant.