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All Journal Jurnal Prima Medika Sains JOURNAL LA MEDIHEALTICO Buletin Kedokteran dan Kesehatan Prima
Djuang, Michelle Hendriani
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Pengaruh variasi pemberian dosis aloksan terhadap angka kadar gula darah hewan coba Dachi, Virent Nifadila O.; Rayyan, Teuku Arif; Utami, Sherlinda Putri; Mutia, Rena; Akbar, Khainir; Lumbantobing, Christina J.R Esmaralda; Kunardi, Sidharta; Jansen, Jansen; Djuang, Michelle Hendriani
Jurnal Prima Medika Sains Vol. 4 No. 1 (2022): Juni
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v4i1.2460

Abstract

Diabetes merupakan penyakit long-term yang dapat terjadi ketika kadar gula dalam darah tinggi sehingga tidak dapat memproduksi zat insulin secara cukup atau insulin tidak dapat bekerja secara efektif. Diperkirakan akan meningkat di tahun 2030 menjadi 552 juta jiwa jika tidak mendapatkan penanganan yang baik. Aloksan merupakan penyebab sel-β pankreas mengalami nekrosis juga sering dipakai sebagai bahan eksperimental dalam topik diabetes dengan kasus yang bervariasi pada hewan seperti tikus, mencit, dan anjing. Studi ini bertujuan untuk menganalisis dan merangkum studi-studi terdahulu mengenai pengaruh variasi pemberian dosis aloksan terhadap angka kadar gula darah hewan coba.
The Effect of Binahong Leaf Extract on Reducing Cholesterol and Histopathological Features in the Liver Trisnawati, Risca; Djuang, Michelle Hendriani; Hutapea, Johnson
Journal La Medihealtico Vol. 5 No. 1 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i1.1098

Abstract

Being overweight or obese raises your risk of elevated cholesterol, triglycerides, and fatty liver. The liver is crucial to metabolic regulation. Essential to preserve liver health. Maintaining your diet, exercising, and eating antioxidants are all options. Many plants contain antioxidants, like Binahong (Anredera cordifolia). This study examines how Binahong leaf extract reduces cholesterol and improves liver function in high-fat-fed Wistar rats (Rattus norvegicus) and their liver histology. An actual experiment or laboratory experimental study is quantitative. 24 Wistar rats were sampled. Binahong leaf extract was the independent variable, cholesterol levels liver histological features were the dependent variable, and a high-fat diet was the precondition. The test animals were put into four groups: control, groups 2, 3, and 4 with Binahong leaf extract at 30mg/BW, 50mg/BW, and 70mg/BW. SPSS normality, homogeneity, and ANOVA tests. If p > 0.05, research results are generally distributed with 0.200 significance. Significant homogeneity was 0.176 > 0.05. Effective One-Way ANOVA test results (0.000 or <0.05). Post Hoc LSD test analysis yielded important values of 0.000.0001 and 0.024 < 0.05. The phytochemical test found flavonoids, alkaloids, saponins, steroids, and tannins in Binahong leaf extract. Binahong leaf extract at 70 mg/BW reduced cholesterol, body weight, and LDL in hypercholesterolemic male white mice best. The study found that Binahong leaf extract's secondary metabolites—flavonoids, alkaloids, saponins, steroids, and tannins—reduce cholesterol, LDL, and body weight in Wistar strain white rats (Rattus Norvegicus) with hypercholesterolemia.
The relationship between the implementation of the five pillars of Community-Led Total Sanitation (CLTS) and the incidence of stunting at Sei Bejangkar Community Health Center Sylvana, Dhini; Husna, Fika Amaliza; Rahmadayani, Fanny; Djuang, Michelle Hendriani; Akbar, Khainir; Ibnu, Syahroni; Djohan, Djohan; Hutagalung, Tommy Rizky; Puspawani, Yeni; Napitu, Sabar Hamonangan Victorianus; Baeha, Ferdinando Motuho; Tarigan, Setia Budi
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7435

Abstract

Researchers were interested in studying the impact of Community-based total sanitation on stunting in the service area of the Sei Bejangkar Health Center since the first survey indicated that 90 toddlers were stunted owing to the effects of inadequate sanitation. The study used a quantitative, cross-sectional methodology. This research was carried out near the Sei Bejangkar Health Center. All of the infants and toddlers in the puskesmas's operational region served as the study's population. Total sampling was used during the sampling process. Univariate, Bivariate, and Multivariate tests were utilized to analyze both main and secondary data in this study. Based on the data, it appears that there is no connection between the halt defecation movement and stunting in toddlers in the sei anchor health center's service area (P value of 0.529 or more than 0.05). Toddlers at the Sei Bejangkar Health Center are less likely to be stunted if open defecation is reduced. The p-value is 0.000, which means it's significantly larger than 0.05 (0.000 > 0.05).
The relationship between the implementation of the five pillars of Community-Led Total Sanitation (CLTS) and the incidence of stunting at Sei Bejangkar Community Health Center Sylvana, Dhini; Husna, Fika Amaliza; Rahmadayani, Fanny; Djuang, Michelle Hendriani; Akbar, Khainir; Ibnu, Syahroni; Djohan, Djohan; Hutagalung, Tommy Rizky; Puspawani, Yeni; Napitu, Sabar Hamonangan Victorianus; Baeha, Ferdinando Motuho; Tarigan, Setia Budi
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7435

Abstract

Researchers were interested in studying the impact of Community-based total sanitation on stunting in the service area of the Sei Bejangkar Health Center since the first survey indicated that 90 toddlers were stunted owing to the effects of inadequate sanitation. The study used a quantitative, cross-sectional methodology. This research was carried out near the Sei Bejangkar Health Center. All of the infants and toddlers in the puskesmas's operational region served as the study's population. Total sampling was used during the sampling process. Univariate, Bivariate, and Multivariate tests were utilized to analyze both main and secondary data in this study. Based on the data, it appears that there is no connection between the halt defecation movement and stunting in toddlers in the sei anchor health center's service area (P value of 0.529 or more than 0.05). Toddlers at the Sei Bejangkar Health Center are less likely to be stunted if open defecation is reduced. The p-value is 0.000, which means it's significantly larger than 0.05 (0.000 > 0.05).
Co-Authors Baeha, Ferdinando Motuho Dachi, Virent Nifadila O. Djohan Djohan Husna, Fika Amaliza Hutagalung, Tommy Rizky Ibnu, Syahroni Jansen, Jansen Johnson Hutapea Khainir Akbar, Khainir Kunardi, Sidharta Lumbantobing, Christina J.R Esmaralda Mutia, Rena Napitu, Sabar Hamonangan Victorianus Puspawani, Yeni Rahmadayani, Fanny Rayyan, Teuku Arif Sylvana, Dhini Tarigan, Setia Budi Trisnawati, Risca Utami, Sherlinda Putri