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Exploring the Potential of Novel Gadolinium-Free Contrast Agents in MRI: A Pilot Study in a Mexican Cohort Juan Felix Ramirez; Matilda Munoz
Sriwijaya Journal of Radiology and Imaging Research Vol. 2 No. 1 (2024): Sriwijaya Journal of Radiology and Imaging Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjrir.v1i2.71

Abstract

Introduction: Gadolinium-based contrast agents (GBCAs) have been instrumental in enhancing MRI diagnostic capabilities. However, concerns about gadolinium deposition and associated adverse events have spurred research into safer alternatives. This pilot study aimed to evaluate the safety and efficacy of a novel gadolinium-free contrast agent (GBCA-X) in a Mexican cohort. Methods: This prospective, single-center study enrolled 30 adult patients scheduled for contrast-enhanced MRI examinations. Patients received GBCA-X intravenously, and MRI scans were performed using standard protocols. Image quality, contrast enhancement, and adverse events were assessed. Results: GBCA-X provided adequate contrast enhancement in all patients, enabling clear visualization of target tissues and pathologies. Image quality was comparable to that achieved with GBCAs. No immediate or delayed adverse events were reported. Conclusion: This pilot study suggests that GBCA-X is a safe and effective alternative to GBCAs. Further studies with larger cohorts and diverse patient populations are warranted to confirm these findings and establish the role of GBCA-X in clinical practice.
Building Community Resilience to Climate Change in Jakarta: A Public Health Approach Integrating Policy, Practice, and Education Jonah Abraham; Andi Fatihah Syahrir; Neva Dian Permana; Matilda Munoz; Sarah Armalia
Community Medicine and Education Journal Vol. 6 No. 1 (2025): Community Medicine and Education Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/cmej.v6i1.700

Abstract

Climate change poses significant and escalating threats to public health in Jakarta, Indonesia, including increased risks of vector-borne diseases, heat-related illnesses, and mental health impacts exacerbated by flooding and displacement. This study examined the current state of community resilience to these climate-related health threats and evaluated the effectiveness of existing policies and educational interventions. A mixed-methods approach was employed, combining a cross-sectional survey of Jakarta residents (n= 850), semi-structured interviews with key stakeholders (n= 25) from government agencies, NGOs, and community organizations, and a policy review of relevant Indonesian and Jakarta-specific regulations and strategic plans. The survey assessed climate change awareness, perceived health risks, adaptive capacity, and access to resources. Interviews explored policy implementation challenges, inter-sectoral collaboration, and community engagement strategies. The policy review analyzed alignment with international best practices and identified gaps. The survey revealed moderate levels of climate change awareness but significant gaps in understanding of specific health risks (62% aware of general climate change, but only 38% aware of the link to dengue fever increase). Perceived adaptive capacity was low, particularly among vulnerable populations (low-income households, those living in flood-prone areas). 75% of respondents in flood-prone areas reported lacking adequate resources to cope with flooding events. Interviews highlighted challenges in inter-sectoral coordination, limited funding for community-based programs, and a lack of culturally appropriate health education materials. The policy review found that while national-level policies exist, Jakarta-specific implementation lags, particularly in integrating health considerations into urban planning and disaster preparedness. In conclusion, building community resilience to climate change in Jakarta requires a multi-pronged approach. This includes strengthening health system preparedness, developing targeted and culturally appropriate health education programs, improving inter-sectoral collaboration, enhancing community engagement, and integrating health considerations into all relevant policies. Specific recommendations include strengthening early warning systems for heat waves and floods, expanding access to clean water and sanitation, promoting climate-resilient housing, and investing in community-based adaptation projects.
Frugal Innovation in Education: Designing and Evaluating Low-Bandwidth, Asynchronous Learning Systems for Remote Indonesian Schools Hesti Putri; Maya Enderson; Jasmila Tanjung; Matilda Munoz; Sarah Armalia; Jovanka Andina; Kevin Setiawan; Sudarto Sudarto; Khalil Jibran; Jasmine Alieva
Enigma in Education Vol. 3 No. 1 (2025): Enigma in Education
Publisher : Enigma Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61996/edu.v3i1.95

Abstract

The promise of educational technology (EdTech) to democratize learning in Indonesia is consistently undermined by a profound digital divide, particularly in remote and archipelagic regions where internet connectivity is poor and infrastructure is limited. This study explores the application of frugal innovation principles as a direct and context-aware strategy to address this challenge. A multi-phase, mixed-methods Design-Based Research (DBR) methodology was employed over 18 months. The study involved the collaborative design, development, and implementation of "Lentera," a low-bandwidth, asynchronous, and offline-first learning system, in six remote primary schools in the Maluku Islands. A quasi-experimental design compared three intervention schools with three control schools over one academic year. Data collection was extensive, including pre- and post-intervention literacy and numeracy assessments, System Usability Scale (SUS) surveys, system usage logs, semi-structured interviews with 18 teachers, and over 80 hours of classroom observation. Data were analyzed using a two-level Hierarchical Linear Model (HLM) to account for the clustered nature of students within schools. The Lentera system demonstrated high feasibility and positive user adoption, with offline peer-to-peer sharing proving to be a critical feature for content distribution. Quantitative analysis revealed a statistically significant and substantial improvement in learning outcomes for the intervention group in both literacy (γ = 11.85, p < 0.001) and numeracy (γ = 12.91, p < 0.001) compared to the control group, after controlling for pre-test scores. The mean System Usability Scale (SUS) score was 78.5, indicating well-above-average usability. Qualitative findings, drawn from a wide range of teacher interviews and classroom observations, highlighted the system's effectiveness in supporting student-centered, differentiated instruction and fostering teacher collaboration, aligning with the core principles of Indonesia's Kurikulum Merdeka. The study provides compelling evidence that frugal innovation, embodied in a context-aware learning system, presents a viable, effective, and scalable pathway to enhancing educational quality and equity in resource-constrained environments.
Rhizomatic Resurgence: Multispecies Storytelling and Ecological Entanglement in Southeast Asian Bio-Art Jasmila Tanjung; Matilda Munoz; Sarah Armalia; Kevin Setiawan; Sudarto Sudarto
Enigma in Cultural Vol. 3 No. 1 (2025): Enigma in Cultural
Publisher : Enigma Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61996/cultural.v3i1.102

Abstract

The Anthropocene epoch has catalyzed a profound shift in contemporary art, with Bio-Art emerging as a critical field for interrogating the complex relationships between humanity, technology, and the non-human world. While significant scholarship has explored Bio-Art in Western contexts, its unique manifestations within Southeast Asia remain underexamined. This study investigated the rise of a specific mode of Bio-Art in this region, characterized by rhizomatic structures, multispecies storytelling, and deep ecological entanglement, offering a vital counter-narrative to anthropocentric perspectives. This research employed a qualitative, multi-sited case study methodology. Four exemplary Bio-Art projects from Indonesia, Thailand, Philippines, and Singapore, created between 2020 and 2024, were purposively selected. A multi-modal analytical approach was utilized, combining formal visual analysis of the artworks, critical discourse analysis of artist statements and curatorial texts, and thematic analysis of semi-structured interviews with the artists and curators. The analysis was theoretically grounded in the concepts of the rhizome (and multispecies ethnography. The analysis revealed four dominant themes. First, artists consistently employed the rhizome as both method and metaphor, creating non-linear, decentralized works that mirrored ecological networks. Second, a significant pattern of weaving technoscience with traditional ecological knowledge (TEK) was identified, where advanced biotechnologies were syncretized with local cosmologies and indigenous practices. Third, the artworks actively engaged in more-than-human narration, displacing the human as the central protagonist and instead foregrounding the agency of fungi, plants, microbes, and other organisms. Finally, these projects cultivated affective ecologies, generating powerful emotional responses in viewers to foster critical engagement with pressing regional issues. In conclusion, Southeast Asian Bio-Art, as examined in this study, represents a significant "rhizomatic resurgence" that challenges and expands the global discourse on ecological art. By entangling advanced science with local heritage and centering non-human agencies, these practices foster a profound sense of ecological interdependence. This research concludes that the region's artists are pioneering unique aesthetic and ethical frameworks for navigating our shared planetary crisis, contributing vital perspectives rooted in the unique biocultural complexities of Southeast Asia.
The Acoustic City: Sonorous Landscapes, Urban Memory, and the Politics of Noise Muhammad Hasan; Jovanka Andina; Matilda Munoz; Emir Abdullah; Ahmad Erza
Enigma in Cultural Vol. 3 No. 2 (2025): Enigma in Cultural
Publisher : Enigma Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61996/cultural.v3i2.110

Abstract

The contemporary city is often conceived through a visual paradigm, yet its character is profoundly shaped by its acoustic environment. This study investigated the urban soundscape as a complex tapestry woven from sound, memory, and power. Focusing on the rapidly urbanizing context of Indonesia, this research explored how sonorous landscapes are produced, experienced, and contested, shaping collective urban memory and becoming arenas for political negotiation. A mixed-methods approach was employed, integrating qualitative ethnographic research with quantitative acoustic analysis. Fieldwork was conducted in two distinct Indonesian urban settings: the megacity of Jakarta and the historically significant city of Palembang. Methods included 60 semi-structured interviews with residents, urban planners, and community leaders; 30 researcher-led soundwalks using participant observation; and acoustic data collection using Class 1 sound level meters at 100 strategic locations. This data was used to create predictive acoustic models of selected neighborhoods using CadnaA sound prediction software to visualize and analyze sound pressure level (SPL) distribution. The findings revealed a rich acoustic lexicon unique to Indonesian cities, characterized by a dynamic interplay of religious sounds (the call to prayer or adzan), commercial vocalizations (street vendor calls), transportation noise, and sounds of community life (gotong royong). Ethnographic data demonstrated that these sounds are potent carriers of urban memory, evoking nostalgia and a sense of belonging, but are also sources of significant social friction. Acoustic models identified "sonorous hotspots" where SPLs consistently exceeded national health recommendations by up to 25 dBA, particularly around transport hubs and commercial districts. A significant disconnect was found between residents' subjective perception of noise and objective decibel measurements, highlighting the cultural mediation of sound. The "politics of noise" manifested in community-level disputes over the volume and timing of mosque loudspeakers and the perceived encroachment of commercial sounds into residential areas. In conclusion, the urban soundscape is not a neutral background but a contested social and political space where identities are asserted and power is negotiated. This study established that in Indonesian cities, sound acts as a crucial medium for constructing urban memory and a site for the subtle, everyday politics of cohabitation. Understanding these sonorous landscapes is essential for developing more inclusive and acoustically just urban planning policies that move beyond simple noise abatement to a more nuanced appreciation of the urban acoustic environment.
Beyond the Green Revolution: A 10-Year Longitudinal Mixed-Methods Analysis of Balinese Subak Socio-Ecological Governance and its Alignment with SDG 2 and SDG 6 Fitriyanti Fitriyanti; Anita Havyasari; Ni Made Nova Indriyani; Jasmila Tanjung; Matilda Munoz; Maya Enderson; Sudarto Sudarto
Indonesian Community Empowerment Journal Vol. 5 No. 1 (2025): Indonesian Community Empowerment Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/icejournal.v5i1.50

Abstract

The global challenges of food insecurity (SDG 2) and water scarcity (SDG 6) require proven, sustainable governance models. Socio-ecological systems (SES) rooted in local wisdom (kearifan lokal) offer resilient alternatives. The Balinese Subak, a UNESCO World Heritage site guided by the Tri Hita Karana philosophy, is a pre-eminent example. This research employed a 10-year (2015-2025) longitudinal, mixed-methods, comparative case study of two Subak systems in Bali. We collected a comprehensive dataset including 1,200 systematic water sampling events (yielding 7,200 analytical data points for pH, TSS, BOD, COD, NO3-N, PO4-P) and a 10-year rolling panel survey (n=2,000 completed survey-years) to assess agricultural and governance metrics. Qualitative data (n=60 interviews, n=24 meeting observations) were thematically analyzed. Generalized Linear Mixed-Effects Models (GLMMs) revealed a statistically significant time-dependent reduction in pollution, including Nitrate (β = -0.21 mg/L/year, p < .001) and BOD (β = -0.15 mg/L/year, p < .001), across both sites. This trend was strongly associated with a validated Social Governance Index (SGI). Critically, rice yields remained stable at a high-productivity average (6.2 t/ha), while chemical pesticide use declined by 48% (p < .001). Qualitative analysis identified the core mechanisms: (1) Tri Hita Karana as an internalized moral framework, (2) ritual calendars as coordination mechanisms, and (3) awig-awig as an adaptive governance system. In conclusion, the Subak system demonstrates a proven, sophisticated, and data-driven framework that operationalizes kearifan lokal to achieve the non-trade-off, simultaneous goals of sustainable agriculture (SDG 2) and clean water (SDG 6). These findings provide robust evidence that such systems are not relics but essential, adaptive governance models for global sustainability.