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The Risk of Adverse Drug-Drug Interactions for Stable Angina Pectoris Patients with Heart Failure Complication Prescribed Polypharmacy Fadillah, Ahmad Aldi; Bakhriansyah, Mohammad; Yustikasari, Intan; Nurikhwan, Pandji Winata; Adiputro, Dwi Laksono
Berkala Kedokteran Vol 19, No 2 (2023)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v19i2.17404

Abstract

Stable angina pectoris (SAP) is an imbalance that occurs when myocardial oxygen need increases disproportionally, causing complaints of chest pain. Uncontrolled SAP can lead to a complication of heart failure (HF). Polypharmacy treatment frequently given to SAP patients with HF complications can be potentially detrimental for them. This study aims to determine the risk of adverse drug-drug interactions in SAP patients with HF complications prescribed polypharmacy. This was an analytic observational study with a cross-sectional approach using retrospective data from medical record data from 2020-2021 among hospitalized patients in cardiology ward Ulin General Hospital, Banjarmasin. Potential drug-drug interactions were determined using the Lexicomp tool from the UpToDate® site. Prevalence Odds Ratio (POR) and 95% Confidence Interval (95%CI) were determined using the Logistic Regression test at the 95% level of confidence. Twenty-four SAP patients with HF were recruited. According to its potential interactions, the most interactions were under category C (82.6%), followed by category B (11.3%) and category D (6.0%). Based on its level of severity, the most common was moderate (77.4%), followed by minor (13.0%) and major (9.5%). SAP patients with HF who were not prescribed polypharmacy had a lower risk of adverse drug-drug interactions by 64.7% compared to polypharmacy users, although it was not statistically difference (crude POR 0.353, 95% CI; 0.360-3.421; p-value = 0.369). This study shows that there is a tendency of lower risk of adverse drug-drug interactions in SAP patients with HF complication prescribed polypharmacy compared to those without polypharmacy, but the association is not statistically significant.
Optimalisasi Kapasitas Kognitif untuk Pencegahan Stunting Melalui Pendekatan Edukasi Multimodal di Desa Sungai Alang: Optimization of Cognitive Capacity for Stunting Prevention Through a Multimodal Educational Approach in Sungai Alang Village Rahman, Fauzie; Laily, Nur; Wulandari, Anggun; Faisal, Muhammad Ali; Yustikasari, Intan; Rifani, Rizqi; Alifa Nayla, Nurul; Rahma, Amelia; Zainal Khadafi, Muhammad; Keisya Filsahani, Nuraida; Azmiyannoor, Muhammad; Mulia Wati, Ratna
Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Vol. 4 No. 2 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jppmi.v4i2.844

Abstract

Tingginya prevalensi stunting di Kabupaten Banjar, Kalimantan Selatan, melatarbelakangi kegiatan pengabdian masyarakat ini. Meskipun edukasi pencegahan stunting telah banyak dilakukan, efektivitasnya pada komunitas dengan pengetahuan awal yang tinggi masih perlu dikaji. Tujuan kegiatan ini adalah untuk mengoptimalkan kapasitas kognitif masyarakat dalam pencegahan stunting melalui pendekatan edukasi multimodal yang integratif. Metode pelaksanaan meliputi penyuluhan kesehatan yang memanfaatkan kombinasi media power point, poster, dan video promosi kesehatan, yang dilaksanakan di Desa Sungai Alang dengan melibatkan 24 peserta. Evaluasi dilakukan melalui pembandingan hasil pre-test dan post-test. Hasil kegiatan menunjukkan peningkatan rata-rata pengetahuan peserta dari 95,00 menjadi 97,08. Secara statistik, tidak ditemukan perbedaan yang bermakna antara pengetahuan sebelum dan sesudah intervensi (p=0,276), yang kemungkinan disebabkan oleh ceiling effect dimana pengetahuan awal peserta sudah tinggi. Namun, secara kualitatif, pendekatan multimodal ini berhasil mempertahankan pemahaman masyarakat dan mendapat respons antusias. Disimpulkan bahwa untuk masyarakat dengan pengetahuan awal tinggi, intervensi edukasi perlu didesain lebih mendalam, aplikatif untuk komunitas dengan pengetahuan awal yang sudah tinggi, dan berkelanjutan dengan melibatkan kader serta fokus pada kelompok berisiko. Kegiatan ini memberikan implikasi penting terhadap pengembangan strategi edukasi stunting yang lebih efektif dan kontekstual
The Relationship Between Immunization, Health Insurance, Family Support, and Health Workers with Stunting Incidence Rahman, Fauzie; Wulandari, Anggun; Laily, Nur; Ali Faisal, Muhammad; Rifani, Rizqi; Yustikasari, Intan; Octaviana Putri, Andini; Anggraini, Lia; Azmiyannoor, Muhamad; Zainal Khadafi, Muhammad; Navijay, Ahmad
Journal of Health and Nutrition Research Vol. 5 No. 1 (2026)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v5i1.985

Abstract

Stunting remains a critical public health concern in Indonesia, with the Banjar Regency—specifically the Aluh-Aluh Public Health Center working area—reporting a persistently high prevalence. Beyond direct nutritional factors, stunting is influenced by underlying determinants such as access to health services and the quality of household caregiving. This study aimed to analyze the associations between immunization status, health insurance ownership, family support, and health worker support with the incidence of stunting among children under five. Methods: A quantitative case-control study was conducted involving 144 children (72 stunted cases and 72 non-stunted controls). Participants were selected through a two-stage sampling process: purposive selection of high-risk villages followed by random selection of eligible children, matched by sex. Data were collected via structured questionnaires and secondary anthropometric data from the e-PPGBM system. Statistical analysis was performed using univariate and bivariate chi-square tests to determine odds ratios (OR) and 95% confidence intervals (CI). The findings indicated no significant associations between stunting and immunization status (p = 1.000), health insurance ownership (p = 0.717), or health worker support (p = 0.074). However, family support was significantly associated with stunting incidence (p = 0.040). Children receiving poor family support had 2.385 times higher odds of being stunted compared to those receiving good support (OR = 2.385; 95% CI = 1.026–5.545). While access to health services is an important framework, household-level caregiving practices—manifested through family support—play a decisive role in stunting prevention in this setting