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All Journal Journal of Pharmaceutical and Health Research Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Journal of Pharmaceutical and Sciences. Indonesian Journal of Science and Pharmacy
Julianty, Siti Muliani
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Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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The Effect of Adding Ethanol Extract of Pomegranate Peel (Punica Granatum L.) on the Sun Protection Factor (SPF) Value of Sunscreen Cream Combination of Avobenzone and Octyl Methoxycinnamate Julianty, Siti Muliani; Ginting, Ernawaty; Sudewi, Sudewi; Rizki, Fanny; Nadia, Syarifah; Saputri, Muharni
Indonesian Journal of Science and Pharmacy Vol. 2 No. 1 (2024): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v2i1.57

Abstract

The compounds contained in pomegranate skin are phenolic acids, flavonoids, and tannins, including anthocyanidin, gallic acid, ellagic acid, ellagitannin, gallotanin, catechin, quercetin, which have antioxidant properties. The benefits of pomegranate peels are that they treat health problems and maintain beautiful skin. This research aimed to see the effect of adding pomegranate peel (Punica granatum L.) ethanol extract on the Sun Protection Factor (SPF) value of a combination of avobenzone and octyl methoxycinnamate sunscreen cream. This research was carried out using experimental methods. The formulation of sunscreen cream preparations uses pomegranate peel ethanol extract in various concentrations. The cream was evaluated to determine its Sun Protection Factor (SPF) value, organoleptic test, homogeneity, pH, emulsion type, and irritation test. The organoleptic test results showed that the cream produced in the blank had no odor and was white, while the cream with the addition of pomegranate peel ethanol extract had a distinctive smell and was brown. The emulsion type test shows the oil in the water type.  The addition of pomegranate peel ethanol extract to each formula increased the sun protection factor (SPF) value of sunscreen preparations. The average SPF value of each formula was FI 12.5956, FII 13.9673, FIII 16 .8205, FIV 17.9187, and FV 18.8437.
Formulasi Sediaan Facial Wash Dari Ekstrak Etanol Kulit Pisang Raja (Musa Paradisiaca L.) Secara In Vitro Julianty, Siti Muliani; Nadia, Syarifah; Yushfi, Melza Rizqan
Journal of Pharmaceutical and Health Research Vol 6 No 2 (2025): June 2025
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v6i2.6392

Abstract

Banana peel (Musa paradisiaca L.) has long been known to have various substances that are beneficial to health. The use of ethanol extract as a solvent also shows great potential to extract bioactive compounds from natural ingredients. One of the most common skin care products used in the skin care industry is Facial Wash. This product is made to cleanse and care for facial skin, such as acne control, anti-aging, or other skin care. This study aims to make a facial wash preparation with active ingredients from natural ingredients, so that it is rational to use as a facial cleanser. The basic facial wash is made first with a mixture of facial wash bases formulated into 4 formulas with varying concentrations. Evaluation of the preparation includes organoleptic tests, homogeneity, pH, spreadability, and irritation tests. All formulas with various homogeneous concentrations, pH 6 - 8, are stable in storage for 8 weeks. The results of the spreadability test meet the requirements of 5-7 cm, the average viscosity ranges from 30.7-34 cPs, the average foam height ranges from 4.0 - 6.2 cm and the results of the irritation test show that it does not cause irritation to the volunteer's skin.
Edukasi Pemanfaatan Tanaman Alami Dalam Pembuatan Sediaan Balsem Kelurahan Empus Langkat Julianty, Siti Muliani; Siahaan, Desy Natalia; Fujiko, Muflihah; Sofia, Vivi
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 4 No 1 (2025): Edisi Januari 2025 - Juni 2025
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v4i1.1575

Abstract

Masyarakat Indonesia tidak asing lagi dengan sediaan balsam dikarenakan balsam memiliki aromatherapy serta memiliki rasa yang hangat saat digunakan. Balsem merupakan sediaan yang penggunaannya dioleskan ke kulit dengan tangan sehingga dapat mengotori dan memberikan rasa panas yang sulit hilang. Pengabdian kepada masyarakat ini bertujuan untuk mewujudkan membagi pengetahuan kepada warga dalam edukasi pemanfaatan tanaman bahan alami dalam pembuatan sediaan balsam. Kegiatan ini dilakukan di Kelurahan Empus, Kab. Langkat, Sumatera Utara. Kegiatan yang dilakukan berupa pemeriksaan kesehatan, pemaparan edukasi dan tanya jawab. Adapun pemeriksaan kesehatan berupa pengecekan tekanan darah dan gula darah, pemaparan materi yang disampaikan terkait edukasi pemanfaatan tanaman bahan alami dalam pembuatan sediaan balsam kepada masyarakat. Hasil kegiatan ini untuk menambah pengetahuan masyarakat dalam memanfaatkan bahan alam sebagai sediaan balsam. Berdasarkan hasil tanya jawab semua peserta yang hadir menyatakan kegiatan ini memberikan manfaat positif serta tertarik dan ingin untuk mencoba memulai memanfaatkan bahan alami yang ada. secara mandiri. Kata kunci : Balsam, Edukasi, Masyarakat, Pengabdian LSEM
Uji aktivitas antioksidan ekstrak etanol dan sari kulit nanas (Ananas comosus (L) Merr) menggunakan metode radical scavenger Nadia, Syarifah; Julianty, Siti Muliani; Tambunan, Ika Julianti; Fujiko, Muflihah
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.455

Abstract

Inheritance, Indonesian society has been utilizing various plants as traditional medicine for preventive measures and treatment of various diseases. The pineapple plant or (Ananas comosus (L) Merr) is one of the plants that is often used for treatment. Pineapple (Ananas comosus (L) Merr) contains flavonoids and phenolics, which are productive as natural antioxidants. This research was carried out using experimental methods. The research included collecting materials followed by plant identification, phytochemical screening, making ethanol extract from pineapple peel, and testing antioxidant activity using the radical scavenger method using a Visible Spectrophotometer. The results of research on pineapple rind Simplicia (Ananas comosus (L) Merr), ethanol extract, and water juice of nans rind contain chemical compounds of alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids and glycosides. Ethanol extract and water juice from pineapple peel have antioxidant activity, which was tested using the radical scavenger method against DPPH (1,1-diphenyl-2-picryhydrazyn) solution. Ethanol extract and water juice from pineapple peel have antioxidant activity, but unlike vitamin C, the antioxidant is categorized as very strong. Meanwhile, the ethanol extract of pineapple peel is categorized as strong, and the water extract of pineapple peel is categorized as medium.
Potensi Antibakteri Ekstrak Etanol Batang Balakka (Phyllanthus emblica L.) terhadap Staphylococcus epidermidis serta Evaluasi Mutu Fisik Krim Nasuha, Nabila; Saputri, Muharni; Tambunan, Ika Julianti; Julianty, Siti Muliani; Br Sitepu, Ulva Wirdana; Syahputri, Nabila; Sinaga, Manuella; Syahputri, Devi Yanti
Journal of Pharmaceutical and Health Research Vol 6 No 3 (2025): October 2025
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v6i3.8525

Abstract

Balakka (Phyllanthus emblica L) is a wild plant, commonly used as a cooking spice called holat. The stem of balakka is believed to contain alkaloids, flavonoids, and tannins that have antibacterial properties. Most previous studies have focused on the fruit and leaves of balakka. On the other hand, Staphylococcus epidermidis bacteria are normal flora on human skin that cause infections. The increasing resistance of these bacteria to antibiotics makes it important to find alternative natural antibacterial agents. The purpose of this study was to examine the antibacterial activity of balakka stem extract and cream against Staphylococcus epidermidis bacteria and to evaluate the physical quality of the cream. This study used experimental methodology. The maceration method used ethanol p.a. on 100 g of balakka stem simplisia. The stages included phytochemical screening, cream formulation with concentrations of 1%, 2%, and 3%, and physical quality tests (organoleptic, homogeneity, emulsion type, pH, viscosity, stability, and irritation). Antibacterial tests were carried out using the agar well diffusion method on extracts and cream preparations. The results showed that 19.30 g of thick extract was obtained, which was positive for alkaloids, flavonoids, and tannins. The resulting cream met physical quality standards, was homogeneous, had an oil-in-water (O/W) emulsion type, a pH of 5.3–6.2, was stable, and did not cause irritation. The antibacterial activity of the extract showed inhibition zones of 14.5 mm (100 mg/ml), 11.5 mm (75 mg/ml), and 8.5 mm (50 mg/ml), while the cream showed 5.5 mm (1%), 7.5 mm (2%), and 9.5 mm (3%). Thus, ethanol extract of balakka stems has potential as an antibacterial agent and can be formulated into a safe cream that meets physical quality standards.
Co-Authors Br Sitepu, Ulva Wirdana Fanny Rizki Sembiring Fujiko, Muflihah Ginting, Ernawaty Nabila Syahputri, Nabila Nadia, Syarifah Nasuha, Nabila Saputri, Muharni Siahaan, Desy Natalia Sinaga, Manuella Sudewi Sudewi Syahputri, Devi Yanti Tambunan, Ika Julianti Vivi Sofia Yushfi, Melza Rizqan