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All Journal Indonesian Journal of Obstetrics & Gynecology Science MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Mandala of Health : A Scientific Journal Medical and Health Journal
Suhartomo, Dalri Muhammad
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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BEETROOT (Beta vulgaris L.) AND ITS POTENTIAL AS AN ANEMIA TREATMENT IN PREGNANCY Fadlilah, Synta Haqqul; Suhartomo, Dalri Muhammad; Yusan, Rizak Tiara; Yudhawan, Indra
Medical and Health Journal Vol 3 No 1 (2023): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2023.3.1.9070

Abstract

Anemia is one of the most common nutritional problems in pregnant women. It is defined as a condition in which the hemoglobin (Hb) level is lower than normal. The main cause of anemia in obstetrics is iron deficiency. To prevent this condition, the Government of Indonesia through the Ministry of Health made a rule by giving iron tablets to pregnant women at least 90 tablets during pregnancy (Kemenkes RI, 2022). However, some people are often bored with this pharmacological therapy due to the nausea and vomiting effect of the iron smell. Therefore, the development of alternative anemia therapy has been done to minimize those problems. One of the herbal ingredients that are being studied for its potential as anti-anemia in pregnancy is beetroot (Beta vulgaris L.). This research is included in the type of literature review. The selected literature is research articles published in the last 10 years (2013 to 2023). There are 10 articles that match the topic of study. A total of 7 publications demonstrated the effect of beetroot on anemia in pregnant women during the pregnancy period, and 2 articles in the post-partum period. A study performed in vivo experiments on pregnant female rats. Almost all of the studies did intervention by giving subjects beetroot juice. Only one study used beets as an intervention as ice cream. The results show that beetroot has the potential to prevent and treat anemia in pregnancy by increasing hemoglobin levels and the amounts of hematocrit. It contains a high level of folic acid which is important for normal cell and tissue growth. The iron content of beetroot also plays an essential role in the human body transporting oxygen to red blood cells, so it helps to cure anemia.
The Potential of Noni (Morinda citrifolia L.) as an Anti-Diabetic Fadlilah, Synta Haqqul; De Silva, Ghea; Suhartomo, Dalri Muhammad; Yusan, Rizak Tiara
MAGNA MEDICA Berkala Ilmiah Kedokteran dan Kesehatan Vol 11, No 1 (2024): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.11.1.2024.83-96

Abstract

Background: Diabetes Mellitus (DM) is still a major health problem in the world today because the prevalence remains increasing. Type 2 diabetes is the most common type of diabetes, accounting for over 90% of all diabetes cases. This disease is characterized by insulin resistance, where the body cannot fully respond to insulin. As a result, glucose levels in the blood continue to increase (hyperglycemia). The main of Type 2 DM management is a healthy lifestyle. In addition, pharmacological therapy is also needed to keep blood glucose levels in diabetics under control. However, antidiabetic medicines can cause some side effects. Therefore, the development of alternative diabetes therapy has been done to minimize side effects. One of the herbal ingredients that are being studied for its potential as an anti-diabetic is noni (Morinda citrifolia L.).Objective: The aim of the study is to review and find out more about the potential of noni (Morinda citrifolia L.) as an anti-diabetic.Methods: This research is included in the type of literature review. The kinds of literature are English and Indonesian language research articles related to the topic searched by using database sources from ProQuest, PubMed, ScienceDirect, and Google Scholar. The research articles were published in the last 10 years (2012 to 2022). Results: There are 14 kinds of literature that match the topic of study. A total of 12 kinds of literature are in vivo studies on animals and 2 literature studies on humans. The result shows that noni has an antidiabetic effect by lowering blood glucose levels and improving other parameters. Parts of Noni that have the potential to control Type 2 DM are fruit and leaves, which can be in the form of extracts, juices, or fermented products. Further research is needed to evaluate the toxicity, the content of active compounds, and the expression of genes related to Type 2 DM for ensuring the mechanism of noni in controlling hyperglycemia. Human studies with more respondents are also needed to confirm the findings of existing studies. Conclusion: Noni has an antidiabetic effect by lowering blood glucose levels and improving other parameters. Based on human studies, noni fruit juice can serve as a suitable addition to the diet of Type 2 DM patients.
PEMANFAATAN DAN INOVASI DAUN KATUK (Sauropus androgynus) SEBAGAI SUPLEMENTASI ASI DI INDONESIA: MINI REVIEW Yudhawan, Indra; Cahyaningrum, Putri Khaerani; Suhartomo, Dalri Muhammad; Fadlillah, Synta Haqqul; Haresmita, Perdana Priya; Hamzah, Hasyrul; Sari, Mely Anita; Wicaksari, Sifa Aulia
Mandala Of Health Vol 17 No 1 (2024): Mandala of Health
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2024.17.1.12017

Abstract

Zat gizi paling penting dalam masa emas pertumbuhan dan perkembangan bayi dalam 6 bulan pertama kehidupan adalah Air Susu Ibu (ASI). ASI mengandung zat gizi lengkap dan memiliki komponen imunitas yang penting bagi untuk pertumbuhan, perkembangan, dan sistem imun bayi. Akan tetapi, tidak semua ibu dapat menghasilkan ASI secara optimal dikarenakan berbagai faktor. Sehingga, sebagian ibu menyusui membutuhkan tambahan asupan berupa suplemen pelancar ASI. Salah satu tanaman yang banyak digunakan adalah daun katuk (Sauropus androgynus). Penelitian ini merupakan studi literatur terkait pemanfaatan daun katuk di Indonesia, sebagian besar pencarian adalah penelitian 5 tahun terakhir untuk mengetahui pemanfaatan dan pengembangan daun katuk di Indonesia. Hasil penelusuran menunjukkan bahwa terdapat efektivitas daun katuk dalam meningkatkan produksi ASI. Inovasi daun katuk sebagai suplementasi ASI banyak dilakukan, baik dalam bentuk makanan, cemilan, maupun minuman instan. Edukasi dan sosialisasi terkait pemanfaatan daun katuk juga telah banyak dilakukan oleh tenaga kesehatan. Namun, penelitian lebih dalam terkait mekanisme aksi daun katuk, serta pengembangannya dalam bentuk sediaan farmasi masih belum banyak dilakukan. Mengingat potensi yang besar dari daun katuk, perlu dilakukan penelitian lanjutan untuk mengeksplorasi mekanisme aksi dan mengembangkan produk daun katuk secara saintifik dalam bentuk nutrasetikal, obat herbal terstandar maupun fitofarmaka.
TORBANGUN (Coleus amboinicus) LEAF AS POTENTIAL NEWCOMER IN GALACTOGOGUE OR BREASTMILK BOOSTER: A NARRATIVE REVIEW Yudhawan, Indra; Daniel, Vino; Cahyaningrum, Putri Khaerani; Fadlilah, Synta Haqqul; Suhartomo, Dalri Muhammad; Wahyudi, Ari; Putra, Akwila Albert Dakusha; Pratiwi, Intan Diah; Hawwin, Nur; Kurniawan, Dhadhang Wahyu
Mandala Of Health Vol 18 No 1 (2025): Mandala of Health: A scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2025.18.1.16222

Abstract

The postpartum period is a critical phase for infant development, and one of the challenges during this time is inadequate or absent lactation, which leads to insufficient breast milk (ASI) production. Baby’s growth and development require an adequate amount of nutrition, especially during 6 months of life. Breast Milk is the most fundamental food for babies, and offers complete nutrition for growth and development. However, some mothers are unable to produce enough breast milk for the baby and need to take supplements to stimulate their milk production. Torbangun or Bangun-bangun (Coleus amboinicus) leaf is empirically used to increase milk production in some areas of Indonesia. Although, the use of torbangun is not widely used and known. This research offers an investigation and review of many references to find out the current research on torbangun, especially in association with breast milk production. The result shows that there are quite a lot of research has been done related to torbangun in increasing breast milk. Torbangun has proven to have significant potential as a supplement for increasing breast milk production. The research is still in a preliminary study and there is still a few research that could elucidate the mechanism of action of torbangun as galactogogue, the accuracy of dosage, phytochemical compound, and its safety. Therefore, further research is strongly suggested to elucidate this aspect, especially in dosage, standardization, mechanism of action, scientific formulation, phytochemical compound along with its activity and its safety.
Association Between Maternal Random Blood Glucose Level and Prematurity at Margono Soekardjo Hospital Purwokerto Rachmayanti, Erma; Priyanto, Edy Priyanto; Winarno, Gatot Nyarumenteng Adhipurnawan; Suhartomo, Dalri Muhammad
Indonesian Journal of Obstetrics & Gynecology Science Volume 8 Nomor 2 July 2025
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v8i2.893

Abstract

Objective: Hyperglycemia is among the most common medical conditions encountered during pregnancy. Its prevalence continues to rise in line with two other global epidemics, obesity and diabetes. Studies have shown that hyperglycemia during pregnancy can induce negative impacts on maternal-fetal well-being, one of which is premature birth. This study aims to investigate the association between maternal random blood glucose (RBG) level and prematurity.Methods: This is an observational analytical study with a cross-sectional approach. The data used in the study were obtained from the medical records of patients who gave birth at Margono Soekarjo Hospital, Purwokerto, from January 2023 to February 2024.Result: This study found an association between high maternal RBG levels and prematurity (P-value < 0.005).Conclusion: High maternal RBG level is a risk factor for prematurity. The result of this study shows that RBG may be used as a practical and efficient alternative method to rule out hyperglycemia in pregnancy when OGTT is difficult to perform.Hubungan antara Kadar Glukosa Darah Sewaktu Maternal dan Kejadian Prematuritas di RS. Margono Soekardjo PurwokertoAbstrakTujuan: Hiperglikemia merupakan salah satu kondisi medis yang paling umum dijumpai selama kehamilan. Prevalensinya terus meningkat seiring dengan dua epidemi global lainnya, yaitu obesitas dan diabetes. Berbagai penelitian telah menunjukkan bahwa hiperglikemia selama kehamilan dapat memberikan dampak negatif terhadap kesejahteraan ibu dan janin, salah satunya adalah kelahiran prematur. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara kadar glukosa darah sewaktu (GDS) maternal dan kejadian prematuritas.Metode: Penelitian ini merupakan studi observasional analitik dengan pendekatan potong lintang. Data yang digunakan berasal dari rekam medis pasien yang melahirkan di RSUD Margono Soekarjo, Purwokerto, pada periode Januari 2023 hingga Februari 2024.Hasil: Dalam penelitian ini ditemukan adanya hubungan yang signifikan antara kadar GDS maternal yang tinggi dan prematuritas (nilai P<0,005).Kesimpulan: Kadar GDS maternal yang tinggi merupakan salah satu faktor risiko terjadinya prematuritas. Berdasarkan hasil penelitian ini, GDS dapat dipertimbangkan sebagai metode alternatif yang praktis dan efisien untuk mendeteksi hiperglikemia dalam kehamilan, terutama ketika pemeriksaan OGTT sulit dilakukan
Co-Authors ARI WAHYUDI Cahyaningrum, Putri Khaerani Daniel, Vino De Silva, Ghea Dhadhang Wahyu Kurniawan Fadlilah, Synta Haqqul Fadlillah, Synta Haqqul Gatot Nyarumenteng Adhipurnawan Winarno Hamzah, Hasyrul Hawwin, Nur Perdana Priya Haresmita, Perdana Priya Pratiwi, Intan Diah Priyanto, Edy Priyanto Putra, Akwila Albert Dakusha Rachmayanti, Erma Sari, Mely Anita Synta Haqqul Fadlilah Wicaksari, Sifa Aulia Yudhawan, Indra Yusan, Rizak Tiara