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All Journal Global Medical and Health Communication Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Jurnal Mandala Pharmacon Indonesia
Radina, Faqih
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Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Clove Extract and Grape Seed Oil Nanoemulsion for Oral Diseases Therapy: Antibacterial and Antioxidant Activities Hartati, Julia; Damayanti, Meta Maulida; Nur, Ismet Muchtar; Furqaani, Annisa Rahmah; Sari, Ajeng Kartika; Rachmawati, Meike; Siddiq, Tita Barriah; Fakih, Taufik Muhammad; Radina, Faqih
Global Medical & Health Communication (GMHC) Vol 11, No 3 (2023)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v11i3.12916

Abstract

The growth of micro-organisms that acquire resistance to most commercially available antibiotics is occurring rapidly. Consequently, a pressing necessity exists to identify and detect new antimicrobial substances. This study aimed to analyze the antioxidant and antibacterial activity of nanoemulsion clove extract and grape seed oil. This research was conducted in June 2023 using experimental methods at the Research Laboratory of the Universitas Islam Bandung Pharmaceutical Study Program by developing a nanoemulsion preparation containing clove extract (Syzygium aromaticum L.) and grape seed oil (Vitis vinifera L.). Antioxidant activity was tested using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Antibacterial activity was tested using the agar diffusion method by measuring the growth inhibitory diameter of Staphylococcus aureus and Streptococcus mutans bacteria and divided into four groups formulas based on the addition of clove extract with different concentrations in the nanoemulsion base (FA=0.25%, FB=0.5%, FC=0.75%, and FD=1%) to see the best results. The result shows nanoemulsion preparations have antioxidant properties in the DPPH test. The FA formula has the highest IC50, namely 1,117.56 ppm. The antibacterial activity of Staphylococcus aureus and Streptococcus mutans has an inhibition zone, although it is still in the category of inhibiting bacterial growth, but does not kill growth. The nanoemulsion formulation, comprising clove extract and grape seed oil, has exhibited exceptional antioxidant properties and substantial antimicrobial efficacy against prevalent oral bacterial strains.
Pengembangan Sediaan Emulgel Ekstrak Etanol Teh Putih dan Minyak Biji Delima dengan Aktivitas Antioksidan dan Fotoprotektif Priani, Sani Ega; Syafnir, Livia; Mulkiya, Kiki; Fitrianingsih, Sri Peni; Radina, Faqih
Jurnal Mandala Pharmacon Indonesia Vol. 10 No. 1 (2024): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v10i1.458

Abstract

White tea and pomegranate seed oil are known to contain many bioactive compounds that make them potentially have antioxidant and photoprotective activities. This study aimed to examine the antioxidant and photoprotective activities of white tea leaf extract and develop it in an emulgel dosage form. White tea is extracted with 70% ethanol at 600C. The extracts were tested for antioxidant activity by the DPPH method and for photoprotective activity by the Mansur method. White tea extract was developed into an emulgel with pomegranate seed oil as the oil phase, stearic acid and TEA as emulsifiers, and viscolam mac 10 as a gelling agent. The results showed that the ethanol extract of white tea had a very strong antioxidant activity with an IC50 value of 10.80 ± 0.75 ppm. White tea ethanol extract also has photoprotective activity with an SPF value of 12.35 ± 0.63, %Te value of 2.13 ± 0.01 %, and %Tp value of 45.13 ± 0.08 % (ultra protection category). White tea extract has been successfully developed into an emulgel preparation with good characteristics and stability in terms of organoleptic, pH, viscosity, spreadability, and rheological behavior. White tea emulgel are stable based on centrifugation and freeze-thaw tests.
Analisis, pengembangan, dan sertifikasi produk madu trigona hasil budidaya masyarakat Fakih, Taufik Muhammad; Hidayat, Aulia Fikri; Soewondo, Budi Prabowo; Darma, Gita Cahya Eka; Nuzulfikri, Rizki; Radina, Faqih; Prayitno, Robby
Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Vol 6 No 3 (2023)
Publisher : University of Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jipemas.v6i3.19680

Abstract

Permasalahan pokok yang dihadapi oleh Desa Tenjolaya, yang menjadi mitra dalam Program Pengembangan Produk Unggulan Mitra (P3UM), melibatkan tantangan terkait praktik budi daya lebah madu serta mendapatkan Sertifikat Produksi Pangan Industri Rumah Tangga (SPP-PIRT) dan Sertifikat Halal dari Kementerian Agama Republik Indonesia. Dalam rangka mencapai hasil yang diharapkan, rencana kegiatan P3UM telah dirancang dan melibatkan beberapa tahap penting, yaitu tahap persiapan, tahap pelaksanaan, tahap pengajuan produk yang telah bersertifikat, tahap pemantauan dan evaluasi aktivitas, serta tahap pelaporan. Berdasarkan pelaksanaan kegiatan tersebut, sejumlah pencapaian signifikan telah berhasil diperoleh. Pertama, melalui proses identifikasi lebah madu, spesies lebah tersebut diidentifikasi sebagai Tetragonula drescheri. Selanjutnya, dalam analisis kualitas madu dari sampel Madu Trigona, hasil menunjukkan bahwa produk ini memenuhi standar kualitas madu budidaya sesuai dengan ketentuan SNI 8664:2018. Selain itu, pelatihan dalam rangka membangun pengetahuan tentang Budidaya Lebah Madu Trigona diadakan, dengan fokus pada potensi wirausaha di bidang ini. Terakhir, produk Madu Trigona dinamai MAZALI dan telah melewati proses pengemasan serta berhasil mendapatkan SPP-PIRT dengan nomor pendaftaran P-IRT 1073204010491-27. Semua pencapaian ini mendukung aspirasi agar produk MAZALI mampu menjadi salah satu produk unggulan yang mewakili Desa Tenjolaya.
Co-Authors Annisa Rahmah Furqaani Aulia Fikri Hidayat Gita Cahya Eka Darma Ismet Muchtar Nur Julia Hartati Meike Rachmawati Meta Maulida Damayanti Mulkiya, Kiki Nuzulfikri, Rizki Prayitno, Robby Sani Ega Priani Sari, Ajeng Kartika Siddiq, Tita Barriah Soewondo, Budi Prabowo Sri Peni Fitrianingsih Syafnir, Livia Taufik Muhammad Fakih