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All Journal Natural Sciences Engineering and Technology Journal Open Access Indonesian Journal of Medical Reviews Jurnal Pengabdian Masyarakat Nian Tana
Kadar Ismah
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Library & Information Science Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Physics Social Sciences Transportation

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Public Health Threat: Detection of Undeclared Dexamethasone and Paracetamol in Jamu Marketed in Kudus, Indonesia Luthfiana Nurulin Nafi’ah; Kadar Ismah; Yanulia Handayani; Gendis Purno Yudanti; Sukarno; Annis Rahmawaty; Alvina Beti Maulia
Natural Sciences Engineering and Technology Journal Vol. 5 No. 1 (2025): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v5i1.61

Abstract

Jamu, Indonesia's traditional herbal medicine, holds significant cultural and medicinal value. However, the adulteration of jamu with undeclared synthetic drugs like dexamethasone and paracetamol poses a severe public health risk. This study aimed to qualitatively identify these drugs in jamu products circulating in Kudus City, Indonesia. Ten jamu samples, representing various brands and forms (powder, capsules), were purchased from local depots in Kudus. Samples were selected based on their indication for pain relief or anti-inflammatory properties, lack of BPOM (Indonesia's Food and Drug Authority) registration, or discrepancies between the registration number on the packaging and the BPOM database. Organoleptic analysis (odor, taste, color, form) was performed, followed by microscopic analysis to identify natural ingredients using their characteristic fragments. Finally, infrared spectroscopy was employed to detect the presence of dexamethasone and paracetamol. Nine out of ten samples displayed BPOM registration numbers that were not verifiable in the official BPOM database, while one sample lacked any registration number. Organoleptic analysis revealed that six samples exhibited distinct herbal odors, often associated with bitter-tasting jamu. Microscopic analysis confirmed the presence of 1-4 natural ingredients in each sample. Notably, infrared spectroscopy identified paracetamol in one sample. In conclusion, the study revealed a concerning trend of unregistered jamu products and adulteration with undeclared paracetamol in Kudus City. This highlights the need for stricter regulatory measures, enhanced surveillance, and public awareness campaigns to ensure the safety and efficacy of jamu.
Peningkatan Kemandirian Masyarakat Melalui Edukasi dan Implementasi Penggunaan Spray Antinyamuk sebagai Pencegahan Demam Berdarah di Desa Kandangmas Kadar Ismah; Aprillia Puspitasari Tunggadewi; Bagus Riyanto; Sukarno Sukarno; Dhea Yeny Artati; Adinda Putri Novianti; Ahmad Humaidi Faris Maulana; Ainun Nadliroh; Aisyah Putti Maghfirah
JPMNT JURNAL PENGABDIAN MASYARAKAT NIAN TANA Vol. 3 No. 3 (2025): Juli: Jurnal Pengabdian Masyarakat Nian Tana
Publisher : Fakultas Ekonomi & Bisnis, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59603/jpmnt.v3i3.923

Abstract

Dengue Hemorrhagic Fever (DHF) is one of the endemic diseases throughout the tropics and some subtropics. In Indonesia, DHF is a serious health problem because its prevalence is quite high cumulatively. In 2024, the prevalence of this disease reached 276 cases spread across nine sub-districts in Kudus Regency. In response to this condition, a community service activity was carried out which focused on the use of natural ingredients that are easily found at home as an alternative solution to prevent DHF, namely lemongrass and orange peel. The purpose of this community service activity is to increase public awareness about DHF and provide practical skills in making natural mosquito repellent spray. The main targets of this activity are the youth of Karang Taruna and residents of Dukuh Sudo, Kandangmas Village. The community service method is carried out by means of direct counseling about DHF, video screenings, making mosquito repellent spray, distributing lemongrass and orange peel mosquito repellent spray and community service. A total of 15 participants consisting of youth of Karang Taruna and residents of Dukuh Sudo showed high enthusiasm throughout the activity. This can be seen from the many questions asked and their desire to immediately try using natural mosquito repellent spray.
Antioxidant Activity of Leucaena leucocephala Lmk.de Wit. N-Hexane Fraction Islamiyati, Ricka; Yanulia Handayani; Kadar Ismah; Gendis Purno Yudanti; Heni Setyoningsih; Sri Fitrianingsih
Open Access Indonesian Journal of Medical Reviews Vol. 3 No. 1 (2023): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v3i1.286

Abstract

Antioxidants are chemical compounds that can neutralize free radical agents. These compounds work by donating electrons to achieve a stable form, thereby inhibiting the oxidative mechanisms that cause degenerative disease. Lamtoro seeds contain many active compounds that can be used as a source of natural antioxidants and antibacterials. This study aimed to determine the antioxidant effect of the n-hexane fraction of lamtoro seeds (Leucaena leucocephala Lmk. de Wit.). This study is an in vitro experimental study. The object of study was the n-hexane fraction of lamtoro seeds, where antioxidant activity was examined using the DPPH method. Analysis was performed using a UV-Vis spectrophotometer. The n-hexane fraction contained a total flavonoid content of 9.224% and had antioxidant activity with an lC50 value of 67.94 ppm. In conclusion, the n-hexane fraction of lamtoro seeds (Leucaena leucocephala Lmk.de Wit.) has strong antioxidant activity.
Co-Authors Adinda Putri Novianti Ahmad Humaidi Faris Maulana Ainun Nadliroh Aisyah Putti Maghfirah Alvina Beti Maulia Annis Rahmawaty Aprillia Puspitasari Tunggadewi Bagus Riyanto Dhea Yeny Artati Gendis Purno Yudanti Heni Setyoningsih Islamiyati, Ricka Luthfiana Nurulin Nafi’ah Sri Fitrianingsih Sukarno Sukarno Sukarno Yanulia Handayani