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All Journal Natural Sciences Engineering and Technology Journal Open Access Indonesian Journal of Medical Reviews Panggung Kebaikan : Jurnal Pengabdian Sosial Svarga Pena: Jurnal Pengabdian Kepada Masyarakat
Yanulia Handayani
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Public Health Threat: Detection of Undeclared Dexamethasone and Paracetamol in Jamu Marketed in Kudus, Indonesia Luthfiana Nurulin Nafi’ah; Kadar Ismah; Yanulia Handayani; Gendis Purno Yudanti; Sukarno; Annis Rahmawaty; Alvina Beti Maulia
Natural Sciences Engineering and Technology Journal Vol. 5 No. 1 (2025): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v5i1.61

Abstract

Jamu, Indonesia's traditional herbal medicine, holds significant cultural and medicinal value. However, the adulteration of jamu with undeclared synthetic drugs like dexamethasone and paracetamol poses a severe public health risk. This study aimed to qualitatively identify these drugs in jamu products circulating in Kudus City, Indonesia. Ten jamu samples, representing various brands and forms (powder, capsules), were purchased from local depots in Kudus. Samples were selected based on their indication for pain relief or anti-inflammatory properties, lack of BPOM (Indonesia's Food and Drug Authority) registration, or discrepancies between the registration number on the packaging and the BPOM database. Organoleptic analysis (odor, taste, color, form) was performed, followed by microscopic analysis to identify natural ingredients using their characteristic fragments. Finally, infrared spectroscopy was employed to detect the presence of dexamethasone and paracetamol. Nine out of ten samples displayed BPOM registration numbers that were not verifiable in the official BPOM database, while one sample lacked any registration number. Organoleptic analysis revealed that six samples exhibited distinct herbal odors, often associated with bitter-tasting jamu. Microscopic analysis confirmed the presence of 1-4 natural ingredients in each sample. Notably, infrared spectroscopy identified paracetamol in one sample. In conclusion, the study revealed a concerning trend of unregistered jamu products and adulteration with undeclared paracetamol in Kudus City. This highlights the need for stricter regulatory measures, enhanced surveillance, and public awareness campaigns to ensure the safety and efficacy of jamu.
Sosialisasi Pemanfaatan Tanaman Serai sebagai Obat Anti Nyamuk untuk Pencegahan Penyakit DBD kepada Masyarakat Desa Cabak Kec. Tlogowunggu Kabupaten Pati Wildayanti Wildayanti; Aprillia Puspitasari Tunggadewi; Mera Putri Pratitis; Yulia Pratiwi; Luthfiana Nurulin Nafi’ah; Gunawan Firmansyah; Yanulia Handayani; Rochim Rochim; Yustisia Permatasari; Diah A’inurrahmawati
Svarga Pena : Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 4 (2024): Desember : Svarga Pena : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Veteran Bangun Nusantara Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/svargapena.v1i4.62

Abstract

Community Service Activities (PKM) occurred in Cabak Village, Tloguwunggu District, Pati Regency. This PKM activity aims to provide socialization about the benefits of lemongrass plants as medicine for preventing dengue fever. Participants in this PKM activity are the people of Cabak Village, Tlogowungu District, Pati Regency. This socialization activity began by providing material on the use of lemongrass plants as medicine including efficacious substances, pharmacological benefits in medicinal plants, and how to process lemongrass plants that are productive as anti-mosquitoes with the help of media in the form of leaflets and brochures to facilitate the delivery of information to the community. This activity was welcomed positively by the Cabak Village Community as seen from the feedback during the Q&A session. The results of the socialization can be seen from the increase in knowledge about how to use lemongrass plants as anti-mosquito drugs to prevent dengue fever.
Sosialisasi tentang Pencegahan DBD dengan Pemanfaatan Biji Pepaya sebagai Larvasida untuk Mengatasi Perkembangan Nyamuk di SMK Duta Karya Aprillia Puspitasari Tunggadewi; Luvita Gabriel Zulkarya; Luthfiana Nurulin Nafi’ah; Yanulia Handayani; Wildayanti Wildayanti; Yulia Pratiwi; Gunawan Firmansyah; Mera Putri Pratitis; Nanda Intan Permatasari
Panggung Kebaikan : Jurnal Pengabdian Sosial Vol. 2 No. 3 (2025): Agustus: Panggung Kebaikan : Jurnal Pengabdian Sosial
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/panggungkebaikan.v2i3.1992

Abstract

Dengue Hemorrhagic Fever (DHF) remains a significant public health challenge in Indonesia, with the increasing prevalence of cases every year. One of the key methods of controlling the spread of DHF is to target the vector, Aedes aegypti mosquitoes, by eradicating their larvae. However, the widespread and continuous use of chemical larvicides has raised concerns regarding the development of mosquito resistance and environmental pollution. This community service activity aimed to provide students at Duta Karya Vocational High School with knowledge and practical skills to use natural, eco-friendly alternatives for controlling mosquito larvae, focusing on papaya seeds (Carica papaya) and alum as natural larvicides. The methods for this activity included interactive counseling, a demonstration on how to produce larvicides using papaya seeds and alum, and an engaging question-and-answer session. Thirty 12th-grade students from the Pharmacy class participated in this activity. The results revealed that the activity was highly effective in increasing the students' understanding and practical ability to independently create and apply natural larvicides. The students expressed a high level of enthusiasm and interest in the topic, actively participating in the discussions and demonstrations. As a result of this community service, the school has expressed interest in incorporating this activity into its School Health Unit (UKS) work program, which will further promote the use of natural, sustainable methods for controlling mosquito populations. The students, now equipped with the necessary skills, are ready to become "jumantik" cadres—community health volunteers responsible for monitoring and preventing mosquito larvae development. This initiative also raised awareness about utilizing organic waste, such as papaya seeds, to create valuable products for the prevention of DHF.
Antioxidant Activity of Leucaena leucocephala Lmk.de Wit. N-Hexane Fraction Islamiyati, Ricka; Yanulia Handayani; Kadar Ismah; Gendis Purno Yudanti; Heni Setyoningsih; Sri Fitrianingsih
Open Access Indonesian Journal of Medical Reviews Vol. 3 No. 1 (2023): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v3i1.286

Abstract

Antioxidants are chemical compounds that can neutralize free radical agents. These compounds work by donating electrons to achieve a stable form, thereby inhibiting the oxidative mechanisms that cause degenerative disease. Lamtoro seeds contain many active compounds that can be used as a source of natural antioxidants and antibacterials. This study aimed to determine the antioxidant effect of the n-hexane fraction of lamtoro seeds (Leucaena leucocephala Lmk. de Wit.). This study is an in vitro experimental study. The object of study was the n-hexane fraction of lamtoro seeds, where antioxidant activity was examined using the DPPH method. Analysis was performed using a UV-Vis spectrophotometer. The n-hexane fraction contained a total flavonoid content of 9.224% and had antioxidant activity with an lC50 value of 67.94 ppm. In conclusion, the n-hexane fraction of lamtoro seeds (Leucaena leucocephala Lmk.de Wit.) has strong antioxidant activity.
Co-Authors Alvina Beti Maulia Annis Rahmawaty Aprillia Puspitasari Tunggadewi Diah A’inurrahmawati Gendis Purno Yudanti Gunawan Firmansyah Heni Setyoningsih Islamiyati, Ricka Kadar Ismah Luthfiana Nurulin Nafi’ah Luvita Gabriel Zulkarya Mera Putri Pratitis Nanda Intan Permatasari Rochim Rochim Sri Fitrianingsih Sukarno Wildayanti Wildayanti Yulia Pratiwi Yustisia Permatasari