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All Journal Indonesian Journal of Obstetrics & Gynecology Science Poltekita: Jurnal Pengabdian Masyarakat
Effendi, Kms. Yusuf
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Effectiveness of Vitamin D Therapy on the Lipid Profile of Patients with Polycystic Ovary Syndrome Usman, Fatimah; Abadi, Adnan; Effendi, Kms. Yusuf; Manan, Heriyadi; Andrina, Hana
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.522

Abstract

Polycystic ovary syndrome (PCOS) is characterized by chronic hyperandrogenism and anovulation that is also associated with various clinical and biochemical features. Vitamin D deficiency is a common problem that affects up to half of the adult population worldwide, including patients with PCOS. Based on these considerations, we are interested in further exploring the effectiveness of vitamin D in improving lipid profiles in PCOS.Efektivitas Terapi Vitamin D pada Profil Lipid Penderita Sindrom Ovarium PolikistikAbstrakSindrom Ovarium Polikistik (PCOS) ditandai dengan hiperandrogenisme kronis dan anovulasi yang juga berhubungan dengan berbagai gambaran klinis dan biokimia. Kekurangan vitamin D adalah masalah umum yang mempengaruhi setengah populasi orang dewasa di seluruh dunia, termasuk pasien PCOS. Tinjauan literatur ini dilakukan untuk mencari artikel asli dan review mengenai pertanyaan spesifik mengenai efektivitas terapi vitamin D terhadap profil lipid pasien PCOS.Kata kunci: PCOS, Lipid, Vitamin D
Penyuluhan Kesehatan Reproduksi Diet Vitamin D pada Remaja Putri di Kota Palembang dengan Dismenore Primer Sepiwiryanti, Wika; Legiran, Legiran; Wardiansah, Wardiansah; Effendi, Kms. Yusuf; Sari, Bunga Anggreini; Ramdiana, Ramdiana
Poltekita: Jurnal Pengabdian Masyarakat Vol. 5 No. 1 (2024)
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v5i1.2237

Abstract

Primary dysmenorrhea is the most frequent gynecological issue in women of reproductive age. Various therapeutic approaches have been used to treat dysmenorrhea, such as psychotherapy, administration of non-steroidal anti-inflammatory drugs, oral contraceptive pills, and others. However, these drugs often have undesirable side effects. Therefore, other alternatives, such as herbal medicine, diet, supplements, vitamins, and minerals, are important concerns. Vitamin D, also known as calciferol, is believed to regulate cell growth and apoptosis and modulate the immune system and other functions. The active type of vitamin D has the potential to decrease prostaglandin production within the endometrium and restrict its biological impact by influencing prostaglandin receptors. Moreover, it can prompt anti-inflammatory responses through diverse pathways. Vitamin D is naturally synthesized in the skin when exposed to sunlight's ultraviolet B (UVB) radiation, but it can also be acquired from dietary sources and supplements. This community service aims to educate young women about dysmenorrhea by increasing participation in counseling. The activity method used was counseling aimed at young female students at STIKES Abdurahman in Palembang, with a total of 120 participants, and this counseling activity was carried out for 150 minutes. From the results of this community service, the students understand the importance of maintaining reproductive health. They can overcome primary dysmenorrhea by adjusting a diet that contains vitamin D.
Correlation of Vitamin D and Antimullerian Hormone Level in Infertile Women with Polycystic Ovary Syndrome and Obesity Usman, Fatimah; Saleh, Irsan; Effendi, Kms. Yusuf; Putra, Hadrians Kesuma; Abadi, Adnan; Siahaan, Salmon Charles Pardomuan Tua; Kesty, Cindy; Rizda, Dian Permata; Stevanny, Bella; Lestari, Peby Maulina
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 3 November 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i3.723

Abstract

Introduction: Increasing amount of research indicates that women with PCOS are more likely to have a shortage in vitamin D with abnormally high anti-Müllerian hormone (AMH) levels. This study aims to assess the correlation between vitamin D and Anti-Mullerian Hormone (AMH) levels in infertile women with polycystic ovarian syndrome (PCOS) and obesity. Method: This observational cross-sectional study examined all obese women with PCOS who sought infertility treatment at Dr. Mohammad Hoesin Hospital Palembang from August 2021 to November 2021. PCOS diagnosis was determined using the Rotterdam criteria. All research subjects underwent a physical examination and transvaginal ultrasound to evaluate body mass index (BMI) and polycystic ovary morphology. Blood samples were collected to evaluate their testosterone, AMH, and vitamin D levels. Statistical analysis was performed using the Spearman correlation test with IBM® SPSS Statistics version 24. Results: Thirty infertile women with PCOS and obesity were included in the study, with average age of 31.17±4.48 years and average BMI of 33.45±2.67 kg/m2. The majority of the subjects had polycystic ovary morphology (86.7%) and oligomenorrhea (76.7%). No correlation between BMI and vitamin D as well as AMH levels was found in infertile women with PCOS and obesity. The Spearman test showed moderate negative correlation (p = 0.011. r = -0.458) between vitamin D and AMH levels in infertile women with PCOS and obesity. Conclusion: There is a moderate negative correlation between vitamin D and AMH levels among infertile women with PCOS and obesity. Further research is required to comprehend the role of vitamin D in female fertility.Korelasi Vitamin D dan Kadar Hormon Anti-Müllerian pada Wanita Infertil dengan Sindrom Ovarium Polikistik dan ObesitasAbstrakPendahuluan: Semakin banyak penelitian melaporkan bahwa wanita dengan PCOS cenderung mengalami defisiensi vitamin D dengan penignkatan kadar hormon anti-Müllerian (AMH). Penelitian ini bertujuan untuk mengkaji hubungan vitamin D dan kadar AMH pada wanita infertil dengan sindrom ovarium polikistik (SOPK) dan obesitas.Metode: Penelitian ini merupakan studi observasional potong lintang terhadap seluruh wanita infertil dengan SPOK dan obesitas yang di RSUP Dr. Mohammad Hoesin Palembang pada bulan Agustus 2021 hingga November 2021. Diagnosis SOPK ditegakkan berdasarkan kriteria Rotterdam. Seluruh subjek penelitian menjalani pemeriksaan fisik dan ultrasonografi transvaginal untuk menilai indeks massa tubuh (IMT) dan morfologi ovarium polikistik. Sampel darah dikumpulkan dari semua wanita untuk mengukur kadar testosteron, AMH, dan vitamin D. Analisis statistik dilakukan dengan menggunakan uji korelasi Spearman menggunakan IBM® SPSS Statistics versi 24.Hasil: Tiga puluh wanita infertil dengan SOPK dan obesitas dilibatkan dalam penelitian ini dengan usia rata-rata 31,17±4,48 tahun dan rata-rata IMT 33,45±2,67 kg/m2. Mayoritas subjek memiliki morfologi ovarium polikistik (86,7%) dan oligomenore (76,7%). Tidak ada korelasi antara IMT dan vitamin D maupun kadar AMH pada wanita infertil dengan SOPK dan obesitas. Uji Spearman menunjukkan korelasi negatif sedang (p=0.011.r=-0.458) antara kadar vitamin D dan AMH pada wanita infertil dengan SOPK dan obesitas. Kesimpulan: Kadar vitamin D berkorelasi negatif dengan kadar AMH pada wanita infertil dengan SOPK dan obesitas. Penelitian lebih lanjut diperlukan untuk memahami peran vitamin D pada kesuburan wanita.Kata kunci: Anti-Müllerian Hormone, Indeks Massa Tubuh, Obesitas, Sindrom Ovarium Polikistik, Vitamin D
Co-Authors Adnan Abadi, Adnan Andrina, Hana Bunga Anggreini Sari Kesty, Cindy Legiran Legiran Manan, Heriyadi Muhammad Irsan Saleh Peby Maulina Lestari, Peby Maulina Putra, Hadrians Kesuma Ramdiana, Ramdiana Rizda, Dian Permata Salmon Charles Pardomuan Tua Siahaan Sepiwiryanti, Wika Stevanny, Bella Usman, Fatimah Wardiansah, Wardiansah