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All Journal Jurnal Imejing Diagnostik Molecular and Cellular Biomedical Sciences (MCBS) Oceana Biomedicina Journal Jurnal Pengabdian Masyarakat (ABDIRA) Journal of Tropical Biodiversity Multidisciplinary Indonesian Center Journal Poltekita: Jurnal Pengabdian Masyarakat
Bunga Anggreini Sari
Universitas Kader Bangsa
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Dentistry Earth & Planetary Sciences Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Healing the Fundamental Unit of Heredity (Gene Therapy): Current Perspective and What the Future Holds Bunga Anggreini Sari; Azalia Talitha Zahra; Ganda Purba Tasti; Ziske Maritska
Molecular and Cellular Biomedical Sciences Vol 5, No 2 (2021)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v5i2.202

Abstract

The ability to make precise adjustments to the human genome has been a goal of healing in which gene also introduces as the fundamental unit of heredity, in biomolecular technology in genetic diseases have opened new knowledge such as gene therapy. Gene therapy is a technique to repair DNA where its usage is to treat the malignancy and inherited genetic diseases. Gene therapy is a choice to the genetic cloth that goals to remedy a sickness this is hard to deal with or perhaps has no treatment. Currently, gene remedy is done in approaches to patients, specifically embryonic cells and somatic cells, every in vivo and ex vivo. Moral considerations with modification of the difficulty's cells and oversight of regulation and reagents want to be taken into consideration within the gene therapy project. Applications for using gene remedies have begun to be widely used, which include in case of maximum cancers, coronary heart disorder, infectious sicknesses, and others. Gene therapy has spread to a wide range of applications then go beyond the modification of genetic disorders. Advances in genetic modification of cancer cells and immunity and the use of viruses and bacteria to control cancer cells have resulted in many clinical trials and product developments for cancer treatment. The miracles and blessings of gene therapy are might believe, but even though they are being studied and developed now and, in the future, so that the desire for gene therapy may be even better future.Keywords: gene therapy, genetic recombination, gene therapy application
Activities of Tembusu Plants (Cyrtophyllum fragrans (Roxb.) DC.) As Medicinal Plants; Literature Review Article Bunga Anggreini Sari; Eddy Mart Salim; Irsan Saleh
Oceana Biomedicina Journal Vol 6 No 2 (2023): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v6i2.90

Abstract

Tembusu (Cyrtophyllum fragrans (Roxb.) DC.) is a plant belonging to the Gentianaceae family that can be used as medicine for various diseases. This study aims to determine the pharmacological effectiveness of the Tembusu plant. The method used in this study is a literature review article (LRA) approach. The literature search used Pubmed, Google Scholar, Scient Direct and Research Gate as sources of electronic data published from 2010 to 2022. The results found 19 literatures that met the criteria. Based on a review of several literatures, it shows that the Tembusu plant has pharmacological activities including antimicrobial, antioxidant, anti-inflammatory, anticancer and antidiabetic activities.
Perbandingan Gambaran Tuba Pada Pemeriksaan Hysterosalpingography (HSG) Dengan Klinis Infertilitas Primer di Rumah Sakit Siloam Sriwijaya Palembang: Studi Kasus Lilis Rosalina; Mustika Fatimah; Muslimah Putri Utami; Rizka Muliani; Bunga Anggreini Sari
Jurnal Imejing Diagnostik (JImeD) Vol 10, No 2 (2024): JULI 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jimed.v10i2.11395

Abstract

Background: In dealing with infertility problems, a deep understanding of the specific causes becomes very important for proper treatment. One of the diagnostic methods often used to assess infertility conditions is hysterosalpingography (HSG). The superiority of HSG lies in its ability to provide clear visual information about the structural condition of the uterus and fallopian tubes, which are key factors in fertilization.Methods: This qualitative descriptive research uses a case study approach conducted at Sriwijaya Siloam Hospital in Palembang to compare the results of HSG examination in primary infertility clinics.Results: In this study, the results of HSG examinations in two patients with clinical primary infertility showed that there was a difference in the picture. The results of the HSG examination in first patient showed both non-patent tubes, where distal occlusion of the right fallopian tube and left peritubal adhesion were found, while in second patient it showed both patent tubes with a positive spill sign.Conclusions: Differences in the results of HSG examinations in primary infertility clinics show the conclusion that even though HSG shows a patent fallopian tube, the couple may still experience primary infertility. This shows that the cause of infertility can come from other factors and requires further evaluation.
Pendidikan Kesehatan Skrining Neonatal Pada Bayi Baru Lahir Untuk Masyarakat Desa Betung Barat, PALI Sari, Bunga Anggreini; Septiani, Tety; Muslimin, Muslimin; Kurnianingsih, Susi; Juniarti, Ariska
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 5, No 2 (2025): Abdira, April
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v5i2.589

Abstract

The infant mortality rate (IMR) serves as a crucial indicator in assessing public health. Congenital abnormalities are one of the leading causes of infant mortality in Indonesia. Neonatal screening aims to detect congenital abnormalities early to improve infants’ quality of life. This community service activity aimed to enhance the knowledge of the residents of Betung Barat Village, Penukal Abab Lematang Ilir, regarding the importance of neonatal screening. The event took place on February 20, 2025, using lectures and discussion methods, attended by 30 participants. Evaluation through pre-test and post-test questionnaires showed a significant increase in knowledge, with the average score rising from 55.3 to 78.7 (p = 0.005). These results indicate that education is effective in improving community understanding of neonatal screening. It is recommended to conduct regular educational programs, involve families in supporting neonatal screening, and enhance access to information through local media and village health volunteers to improve infant health from an early stage.
Penyuluhan Kesehatan Reproduksi Diet Vitamin D pada Remaja Putri di Kota Palembang dengan Dismenore Primer Sepiwiryanti, Wika; Legiran, Legiran; Wardiansah, Wardiansah; Effendi, Kms. Yusuf; Sari, Bunga Anggreini; Ramdiana, Ramdiana
Poltekita: Jurnal Pengabdian Masyarakat Vol. 5 No. 1 (2024)
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v5i1.2237

Abstract

Primary dysmenorrhea is the most frequent gynecological issue in women of reproductive age. Various therapeutic approaches have been used to treat dysmenorrhea, such as psychotherapy, administration of non-steroidal anti-inflammatory drugs, oral contraceptive pills, and others. However, these drugs often have undesirable side effects. Therefore, other alternatives, such as herbal medicine, diet, supplements, vitamins, and minerals, are important concerns. Vitamin D, also known as calciferol, is believed to regulate cell growth and apoptosis and modulate the immune system and other functions. The active type of vitamin D has the potential to decrease prostaglandin production within the endometrium and restrict its biological impact by influencing prostaglandin receptors. Moreover, it can prompt anti-inflammatory responses through diverse pathways. Vitamin D is naturally synthesized in the skin when exposed to sunlight's ultraviolet B (UVB) radiation, but it can also be acquired from dietary sources and supplements. This community service aims to educate young women about dysmenorrhea by increasing participation in counseling. The activity method used was counseling aimed at young female students at STIKES Abdurahman in Palembang, with a total of 120 participants, and this counseling activity was carried out for 150 minutes. From the results of this community service, the students understand the importance of maintaining reproductive health. They can overcome primary dysmenorrhea by adjusting a diet that contains vitamin D.
Perbandingan Gambaran Tuba Pada Pemeriksaan Hysterosalpingography (HSG) Dengan Klinis Infertilitas Primer di Rumah Sakit Siloam Sriwijaya Palembang: Studi Kasus Rosalina, Lilis; Fatimah, Mustika; Utami, Muslimah Putri; Muliani, Rizka; Sari, Bunga Anggreini
Jurnal Imejing Diagnostik (JImeD) Vol. 10 No. 2 (2024): JULI 2024
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jimed.v10i2.11395

Abstract

Background: In dealing with infertility problems, a deep understanding of the specific causes becomes very important for proper treatment. One of the diagnostic methods often used to assess infertility conditions is hysterosalpingography (HSG). The superiority of HSG lies in its ability to provide clear visual information about the structural condition of the uterus and fallopian tubes, which are key factors in fertilization.Methods: This qualitative descriptive research uses a case study approach conducted at Sriwijaya Siloam Hospital in Palembang to compare the results of HSG examination in primary infertility clinics.Results: In this study, the results of HSG examinations in two patients with clinical primary infertility showed that there was a difference in the picture. The results of the HSG examination in first patient showed both non-patent tubes, where distal occlusion of the right fallopian tube and left peritubal adhesion were found, while in second patient it showed both patent tubes with a positive spill sign.Conclusions: Differences in the results of HSG examinations in primary infertility clinics show the conclusion that even though HSG shows a patent fallopian tube, the couple may still experience primary infertility. This shows that the cause of infertility can come from other factors and requires further evaluation.
KEGIATAN PENGABDIAN KEPADA MASYARAKAT (PKM) HOLISTIK PADA BIDANG KESEHATAN DI DESA SUKA MERINDU OGAN ILIR SUMATERA SELATAN Fatimah, Mustika; Diana Sartika; Nova Mabela; Dinda Rahma; Rapi Dzaki Almugni; Devina Liya; Dita Rahmalia; Muslimah Putri Utami; Anisah; Harry Wahyudhy Utama; Devi Marlina; Bunga Anggreini Sari
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 1 No. 3 (2024): Vol. 1 No. 3 Edisi Juli 2024
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v1i3.154

Abstract

Pengabdian Kepada Masyarakat (PKM) di bidang kesehatan di desa berkaitan kebutuhan akan peningkatan akses ke layanan kesehatan yang berkualitas dan pemberdayaan masyarakat setempat. Beberapa masalah bidang kesehatan di desa antara lain fasilitas kesehatan sering kali jauh dan tidak memadai, ada kekurangan tenaga kesehatan yang bersedia bekerja di daerah pedesaan, pendidikan kesehatan yang kurang memadai berakibat pada kesalahpahaman mengenai praktik kesehatan yang baik, dan desa-desa sering menghadapi beban penyakit yang tinggi. Desa Suka Merindu merupakan salah satu desa di Ogan Ilir dengan jumlah penduduk sebanyak 1111 jiwa dan luas wilayah 850 ha/m2. Fasilitas layanan kesehatan berupa puskesmas dan posyandu terletak menyebar di dekat beberapa desa di sekitarnya. Masalah kesehatan di Desa Suka Merindu bervariasi mulai dari masalah penyakit tidak menular, penyakit menular hingga penyalahgunaan Narkotika, Psikotropika, dan Zat Adiktif (NAPZA). Pengabdian ini dilakukan di Desa Suka Merindu pada bulan Januari 2024. Ada empat kegiatan PKM holistik yang dilakukan adalah pemeriksaan dan edukasi gratis kepada warga, penyuluhan kesehatan reproduksi dan pencegahan anemia di kalangan remaja dengan pemberian Tablet Tambah Darah (TTD) kepada remaja putri Sekolah Menengah Atas (SMA), sosialisasi mengenai Infeksi Saluran Pernapasan Akut (ISPA) dan Hipertensi di Puskesmas, dan penyuluhan mengenai bahaya penyalahgunaan NAPZA di balai desa. Tahapan masing-masing kegiatan terdiri dari perencanaan, analisis situasi, studi literatur, survei awal, koordinasi perizinan dan kesediaan sasaran, persiapan materi, alat dan bahan, pelaksanaan yang terdiri dari tanya jawab awal, penyampaian materi, diskusi, dan penyerahan poster serta evaluasi. Sesuai dengan tujuan kegiatan, hasil kegiatan tercapai berupa penyampaian materi dan terwujudnya diskusi. Melalui PKM di bidang kesehatan, ada peluang untuk mengatasi ketidaksetaraan dalam layanan kesehatan dan memperbaiki kualitas hidup penduduk desa. Ini juga membantu dalam mengidentifikasi dan mengatasi kebutuhan kesehatan yang spesifik dari komunitas yang mungkin tidak tercakup dalam kebijakan kesehatan yang lebih luas.
Comprehensive Inventory and Medicinal Potential of Macroalgae in Cibuaya Beach Coastal Ecosystem, Ujung Genteng, Sukabumi Effendi, Alvira Noer; Fadhillah, Hilwa Syifa; Khairunisah, Siti Delvia; de’Ornay, Amelia Rina Nogo; Sari, Bunga Anggreini; Handayani , Sri
Journal of Tropical Biodiversity Vol 4 No 2 (2024): April 2024
Publisher : Universitas Nasional Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59689/bio.v4i2.217

Abstract

The potential for macroalgae diversity along the coast of Cibuaya Beach, Pangumbahan Village, Ujung Genteng, Sukabumi Regency, West Java, is illustrated in this study. Macroalgae, recognized as integral components of marine ecosystems, have garnered attention due to their substantial economic value and ecological benefits. This study aims to conduct an inventory and identification of macroalgae in this specific locale. The quadratic transect method was employed to provide a comprehensive overview of macroalgae types in the area. The identification results revealed the presence of 25 macroalgae types from 19 tribes and 3 divisions. The diversity assessment yielded a moderate value (2.4) at station 1, while station 2 exhibited a lower diversity level with a value of 1.06, indicating higher species diversity at station 1. Analysis of dominance, as measured by the dominance index, indicated a low level (0.13) at station 1 and a medium level (0.59) at station 2, with Boergesenia forbesii emerging as the dominant type at both stations. These findings contribute to a deeper understanding of macroalgae diversity potential along the Cibuaya Coast, providing crucial insights to support marine conservation efforts in the region and serving as a cornerstone for further ecological investigations. Furthermore, considering the proven medicinal potential of macroalgae in prior studies, these findings underscore the significance of this research in the realm of potential drug development and nature-based therapies.
Co-Authors ANISAH Azalia Talitha Zahra Devina Liya de’Ornay, Amelia Rina Nogo Diana Sartika Dinda Rahma Dita Rahmalia Eddy Mart Salim Effendi, Alvira Noer Effendi, Kms. Yusuf Fadhillah, Hilwa Syifa Ganda Purba Tasti Handayani , Sri Harry Wahyudhy Utama Irsan Saleh Juniarti, Ariska Khairunisah, Siti Delvia Kurnianingsih, Susi Legiran Legiran Lilis Rosalina Marlina, Devi Muliani, Rizka MUSLIMAH PUTRI UTAMI Muslimin Muslimin MUSTIKA FATIMAH Nova Mabela Ramdiana, Ramdiana Rapi Dzaki Almugni Rosalina, Lilis Sepiwiryanti, Wika Tety Septiani Wardiansah, Wardiansah Ziske Maritska