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IN VIVO ACUTE TOXICITY OF ALOIN EXTRACT ON MALE WHITE MICE (Mus musculus) Vani, Ade Teti; Putri, Amalia Rahma; Abdullah, Dessy Abdullah; Dewi, Nadia Purnama; Triansyah, Irwan
MSJ : Majority Science Journal Vol. 2 No. 1 (2024): MSJ-February
Publisher : PT. Hafasy Dwi Nawasena

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61942/msj.v2i1.101

Abstract

Aloin has many benefits potential as a medicine. However, it is necessary to carry out toxicity tests on experimental animals as a pre-screening test. Toxic effect parameters were seen from changes in body weight, tremors, convulsions, salivation, weakness, walking backward, walking on the stomach, death, and levels of SGOT and SGPT in experimental animals. This study aims to evaluate the in vivo acute aloin toxicity test results in mice (Mus Musculus) regarding potential toxic symptoms and animal death. A sample of 27 mice were separated into three groups for this investigation: the control group, the treatment group I at a dose of 2500 µg/kg BW, and the treatment group II at an amount of 5000 µg/kg BW, and 5 mice in the preliminary test. This study employed a laboratory experimental test method using a pre-post control group design study. Based on observations of experimental animals, it concluded neither the preliminary test nor the toxicity test revealed any toxic signs. Neither the initial test nor the toxicity test resulted in any observed animal fatalities. Before and after aloin administration, changes in body weight were significantly different. Treatment group II, treatment group I, and the control group's SGOT levels were classified from highest to lowest, with subsequent values of 22.4 U/L, 21.9 U/L, and 19.9 U/L. The highest value of 35.7 U/L, 32.1 U/L, and 26.2 U/L in the treatment groups II, I, and the control group was used to rank the SGPT levels. There were no toxic symptoms and no mortality in experimental animals, so it can be concluded that aloin did not cause harmful effects in mice, so it was categorized as a pseudo-lethal dose.
Penerapan Konseling Kelompok dengan Teknik Cognitive Restructuring untuk Mengurangi Insecurity pada Remaja:Penelitian Tindakan Bimbingan dan Konseling Windasantika, Windasantika; Nuraisyah, Nuraisyah; Nurjannah, Nurjannah; Putri, Amalia Rahma
Invention: Journal Research and Education Studies Volume 6 Nomor 1 Maret 2025
Publisher : CV. PUSDIKRA MITRA JAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51178/invention.v6i1.2493

Abstract

This study aims to reduce insecurity levels among adolescents through the application of group counseling using the Cognitive Restructuring technique. The research employed a Guidance and Counseling Action Research (PTBK) method across two cycles, involving six eighth-grade students from SMPN 10 Medan identified as having high levels of insecurity. The Cognitive Restructuring technique is designed to help individuals shift negative thinking patterns into more rational and adaptive ones. The results showed a decrease in the average insecurity score from 44.83 (pre-test) to 37.17 (post-test), with a significance value of 0.026 (p < 0.05), indicating a significant effect of the intervention. Normality tests and paired t-tests confirmed the effectiveness of the counseling approach. Thus, group counseling using the Cognitive Restructuring technique has been proven effective in helping adolescents overcome feelings of insecurity and improve their self-confidence.
Penerapan Teknik Untung Rugi Dalam Mengurangi Kecanduan Menonton Drama Korea dalam Konseling Individu Siswa Kelas X di SMK Negeri 3 Kota Medan Putri, Amalia Rahma; Syaimi, Khairina Ulfa; Nurlaili, Nurlaili; Khairani, Rhiza
PEMA Vol. 5 No. 2 (2025)
Publisher : Perkumpulan Manajer Pendidikan Islam Indonesia (PERMAPENDIS) Prov. Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56832/pema.v5i2.1396

Abstract

Fenomena Korean Wave (Hallyu), khususnya Drama Korea (K-Drama), telah menyebar luas berkat kemajuan teknologi, memengaruhi berbagai kalangan di Indonesia, terutama remaja. Meskipun populer sebagai hiburan, kegemaran berlebihan terhadap K-Drama dapat menimbulkan kecanduan yang berdampak negatif pada aspek kehidupan siswa, seperti penurunan prestasi akademik, gangguan tidur, dan kelalaian tanggung jawab. Studi kasus pada siswa berinisial K di SMKN 3 Medan menunjukkan bahwa kecanduan ini bahkan berujung pada penyitaan gawai oleh orang tua. Penelitian ini bertujuan untuk mengurangi kecanduan menonton Drama Korea pada siswa melalui konseling individu dengan menerapkan teknik untung rugi. Menggunakan pendekatan Penelitian Tindakan Layanan (PTL), data dikumpulkan melalui observasi partisipatif, angket, dan wawancara, dengan kolaborasi dari guru BK. Hasil penelitian yang dilaksanakan dalam tiga siklus menunjukkan penurunan signifikan tingkat kecanduan pada subjek. Siklus pertama berfokus pada peningkatan kesadaran siswa tentang dampak negatif kecanduan. Siklus kedua membantu siswa mengatasi pemikiran irasional. Puncaknya pada siklus ketiga, penguatan perilaku positif diberikan melalui kontrak perilaku berbasis teknik untung rugi. Pasca-intervensi, siswa K menunjukkan perubahan positif yang nyata, meliputi durasi menonton yang lebih terkontrol, peningkatan pola tidur dan energi, alokasi waktu yang lebih baik untuk belajar dan hobi, serta perasaan yang lebih positif. Selain itu, siswa juga menunjukkan pemahaman yang lebih baik tentang pemicu kecanduan dan strategi pengelolaannya. Disimpulkan bahwa penerapan teknik untung rugi dalam konseling individu efektif dalam membantu siswa mengurangi kecanduan menonton Drama Korea. Penelitian ini juga menggarisbawahi pentingnya pemberian informasi rasional untuk optimalisasi penerimaan dan penerapan teknik oleh klien.
Penerapan Konseling Kelompok dengan Teknik Cognitive Restructuring untuk Mengurangi Insecurity pada Remaja:Penelitian Tindakan Bimbingan dan Konseling Windasantika, Windasantika; Nuraisyah, Nuraisyah; Nurjannah, Nurjannah; Putri, Amalia Rahma
Invention: Journal Research and Education Studies Volume 6 Nomor 1 Maret 2025
Publisher : CV. PUSDIKRA MITRA JAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51178/invention.v6i1.2493

Abstract

This study aims to reduce insecurity levels among adolescents through the application of group counseling using the Cognitive Restructuring technique. The research employed a Guidance and Counseling Action Research (PTBK) method across two cycles, involving six eighth-grade students from SMPN 10 Medan identified as having high levels of insecurity. The Cognitive Restructuring technique is designed to help individuals shift negative thinking patterns into more rational and adaptive ones. The results showed a decrease in the average insecurity score from 44.83 (pre-test) to 37.17 (post-test), with a significance value of 0.026 (p < 0.05), indicating a significant effect of the intervention. Normality tests and paired t-tests confirmed the effectiveness of the counseling approach. Thus, group counseling using the Cognitive Restructuring technique has been proven effective in helping adolescents overcome feelings of insecurity and improve their self-confidence.