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Silica from Natural Sources: a Review on the Extraction and Potential Application as a Supporting Photocatalytic Material for Antibacterial Activity Annisa Luthfiah; Yusi Deawati; M. Lutfi Firdaus; Iman Rahayu; Diana Rakhmawaty Eddy
Science and Technology Indonesia Vol. 6 No. 3 (2021): July
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2380.895 KB) | DOI: 10.26554/sti.2021.6.3.144-155

Abstract

Silica has become a popular material due to its high abundance and many advantages in various fields. This material can be produced synthetically and extracted from nature with resultant advantages in the application of green production. Therefore, this article deals with the form of silica extracted from quartz sand, leaves, and agricultural wastes found in nature. The extraction process from various sources would be described using thermal, biological, and chemical methods. This review also highlights the potential application of silica as a photo catalytic antibacterial-supporting material and discusses its role in increasing the effectiveness of the process. The discussion was continued with research on this procedure, where synthetic auxiliary materials were compared to the extracted silica. Furthermore, results obtained indicated that the extracted material had very good potential as a photocatalyst adjunct in its application in the antibacterial field.
SINTESIS NANOPARTIKEL MAGNETIK DENGAN METODE KOPRESIPITASI TOGAR SARAGI; BAYU PERMANA; MALA SAPUTRI; LUSI SAFRIANI; IMAN RAHAYU; RISDIANA RISDIANA
Jurnal Material dan Energi Indonesia Vol 7, No 02 (2017)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (706.832 KB) | DOI: 10.24198/jmei.v7i02.15393

Abstract

Nanopartikel magnetik, oksida besi  magnetit (Fe3O4), merupakan material yang menarik untuk dikembangkan. Material ini sangat potensial untuk dapat diaplikaikan secara luas diberbagai bidang seperti untuk diagnosa medik. Namun, untuk menghasilkan Fe3O4 berukuran nano (10-100 nm) masih sulit untuk dilakukan. Pada penelitian ini telah berhasil disintesis nanopartikel Fe3O4 dengan menggunakan metode kopresipitasi. Sintesis dilakukan menggunakan prekursor Ferrous Chloride Tetrahydrate (FeCl2.4H2O) dan Ferric Chloride Anhydrous (FeCl3.6H2O) dengan perbandingan ion ferrous dan ion ferric adalah 1:2. Kemudian, Ammonium Hidroksida (NH3.H2O) digunakan sebagai bahan presipitan. Morfologi partikel dari sampel dikarakterisasi menggunkan Transmission Electron Microscope (TEM).Berdasarkan hasil karakterisasi TEM diperoleh morfologi partikel berbentuk bulat dengan ukuran rata-rata berkisar 10 nm
Protein Modelling Insight to the Poor Sensitivity of Chikungunya Diagnostics on Indonesia’s Chikungunya Virus Bevi Lidya; Muhammad Yusuf; Umi Baroroh; Korry Novitriani; Bachti Alisjahbana; Iman Rahayu; Toto Subroto
Indonesian Journal of Chemistry Vol 23, No 5 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.79301

Abstract

Sensitive detection of infectious diseases is crucial for effective clinical care. However, commercial rapid tests may be limited in their ability to detect pathogen variants across different countries. It was found that the sensitivity of a chikungunya rapid test on local strain was only 20.5% as compared to the East, Central, and South Africa (ECSA) phylogroup. Therefore, the development of geographically specific diagnostics is essential. Investigating the distinctive structural properties of a locally sourced antigenic protein is an important initiative for the development of a specific antibody. This study utilized structural bioinformatics and molecular dynamics simulations to investigate the differences between the E1-E2 antigenic proteins of the Indonesian chikungunya virus (Ind-CHIKV) and that of ECSA. The results showed that some of the mutation points are located at the antibody binding sites of Ind-CHIKV. G194S and V318R mutations were proposed as distinctive features of Ind-CHIKV, leading to weaker antibody binding compared to ECSA. It suggests that modifying the antibody to accommodate bulkier side chains at positions 194 and 318 could improve its effectiveness against Ind-CHIKV. These insights are valuable for developing a highly sensitive immunoassay for Ind-CHIKV and other regional pathogens, ultimately enhancing diagnostic capabilities in Indonesia.