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Vinski, Natasha Cinta
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Computer Science & IT Economics, Econometrics & Finance Engineering Health Professions Law, Crime, Criminology & Criminal Justice Social Sciences

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Stem Cell Therapy for Men’s Vitality in Supporting National Health and Defense: A Comprehensive Review and Meta-Analysis Vinski, Deby Susanti Pada; Trofimova, Svetlana; Pujowaskito, Prihati; Wibowo, Markus; Vinski, Natasha Cinta
Journal of World Science Vol. 4 No. 3 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i3.1317

Abstract

This comprehensive review and meta-analysis examines the efficacy of stem cell therapy in enhancing men’s vitality while supporting national health and defense systems. Patient care records served as the primary source of data for evaluation and analysis, ensuring that real-world clinical outcomes were robustly captured. The study also evaluated the quality assurance of stem cell products cultured by the integrated Celltech Stem Cell Centre Laboratory and Banking, affirming that these products meet stringent clinical standards. Findings indicate that stem cell therapy possesses significant regenerative potential, particularly in repairing damaged cells. Notably, several patients who underwent therapy at the Celltech Stem Cell Center experienced remarkable functional recovery. These results underscore the therapeutic promise of stem cells not only for individual patient recovery but also as a strategic component in enhancing overall public health and national defense readiness.
The Role of Mesenchymal Stem Cells in Stroke Recovery: A Regenerative Medicine Approach with Medical Rehabilitation Vinski, Deby Susanti Pada; Sinjari, Bruna; Ernandini, Endang; Vinski, Natasha Cinta; Nugroho, Andi Kurniawan
Journal of World Science Vol. 4 No. 4 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i4.1404

Abstract

This study examines the role of mesenchymal stem cells (MSCs) in stroke recovery, exploring their regenerative properties and potential to enhance rehabilitation outcomes. Stroke remains a leading cause of long-term disability, with limited treatment options for functional recovery. This research investigates how MSC therapy, combined with conventional rehabilitation methods, can improve motor and cognitive function in stroke patients. Using case studies and patient care records, the study analyzes the effectiveness of MSC therapy in promoting neural repair, reducing disability levels, and improving overall quality of life. The findings suggest that MSC therapy significantly enhances functional recovery when integrated with rehabilitation, particularly when cerebrospinal fluid treatment is used before MSC administration. Imaging and biomarker analyses support these results, showing improvements in neurogenesis, synaptic plasticity, and reduced neuroinflammation. This research highlights the synergistic effects of MSC therapy and rehabilitation, presenting a promising approach to stroke recovery. The study also emphasizes the need for further research to optimize MSC-based treatments, refine delivery methods, and evaluate long-term safety and effectiveness. The implications of this study contribute to the development of integrated therapeutic strategies for stroke patients, offering a more holistic approach to recovery.
Perspective of Gene Therapy for Regenerative Medicine: The Future of Complex Disease and Regenerative Application Pada Vinski, Deby Susanti; Griffin, Darren; Trofimova, Svetlana; Vinski, Natasha Cinta; Parish, Elizabeth
Journal of World Science Vol. 4 No. 6 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i6.1429

Abstract

Recent breakthroughs in biotechnology have significantly advanced the potential to regenerate damaged human tissues. Innovations in stem cell science, genetic engineering, and tissue scaffolding have rapidly pushed the boundaries of regenerative medicine. Yet, numerous technical hurdles remain, particularly concerning the clinical application of gene therapy. Core objectives of gene therapy include enhancing protein synthesis within cells, suppressing overactive genes, and rectifying dysfunctional cellular mechanisms linked to disease. While viral vectors remain dominant in current clinical trials due to their effectiveness, they carry risks of immune reactions and pathogenicity. This has sparked increased interest in non-viral alternatives, which promise greater safety and versatility. Non-viral delivery methods utilize plasmid DNA systems and synthetic carriers to transport therapeutic genes and show great potential, especially when integrated with tissue engineering techniques. By combining these non-viral tools with regenerative approaches, researchers aim to more precisely control the spatial and functional behavior of introduced genes within the body. This review critically assesses the evolution and challenges of gene therapy within the broader scope of regenerative medicine, with an emphasis on emerging non-viral delivery systems and their translational promise.
Advancements In Stem Cell Therapy For Pulmonary Fibrosis: A Comprehensive Review With Vinski Protocol Vinski, Deby Susanti Pada Vinski; Quintosa, Jaime Rodriguez; Ibnu Hajar, Andi; Vinski, Natasha Cinta; Kurniawan Nugroho, Andi
Journal of World Science Vol. 4 No. 9 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i9.1503

Abstract

Pulmonary fibrosis (PF) is a progressive interstitial lung disease characterized by scarring of lung tissue and limited treatment options, resulting in high morbidity and poor prognosis. Mesenchymal stem cell (MSC) therapy has emerged as a promising regenerative intervention due to its potential for immunomodulation, epithelial repair, and anti-fibrotic effects. This review synthesizes current clinical and observational studies involving human participants, highlighting the safety and preliminary therapeutic benefits of MSCs in managing PF and related pulmonary conditions. Several clinical trials involving patients with idiopathic pulmonary fibrosis and COVID-19-associated lung injury demonstrated favorable safety profiles and trends toward improved pulmonary outcomes. Additionally, observational findings from the application of the Vinski Protocol at Celltech Stem Cell Centre provide further support for the regenerative capabilities of MSCs. While current human studies are encouraging, further large-scale and long-term clinical trials are essential to validate the efficacy of MSC therapy and establish standardized treatment protocols for PF.
Stem Cell Therapy For Men’s Vitality: A Comprehensive Review And Meta-Analysis Susanti Vinski, Deby; Quintosa , Jaime Rodriguez; Trofimova , Svetlana; Nugroho, Andi Kurniawan; Vinski, Natasha Cinta; Hardjo, Marhaen
Journal of World Science Vol. 3 No. 9 (2024): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v3i9.722

Abstract

One of the many potential benefits of stem cell therapy is that it may enhance men’s vitality by addressing conditions such as erectile dysfunction and hypogonadism. The current comprehensive review and meta-analysis evaluate the efficacy, safety, and mechanisms of stem cell therapy in improving male sexual health. Data from previously published clinical trials, reviews, and preclinical studies indicate that stem cell therapy significantly enhances erectile function, increases testosterone levels, and improves sperm quality. The regenerative potential of mesenchymal stem cells (MSCs), including their ability to differentiate into various cell types and secrete bioactive molecules, underpins these benefits. Additionally, MSCs modulate the immune response, reducing inflammation and promoting tissue repair. Despite these promising results, current research is limited by heterogeneity among studies, lack of long-term data, and the absence of standardized treatment protocols. Future research can focus on large-scale randomized controlled trials with standardized protocols to validate the long-term efficacy and safety of stem cell therapy. The results of the review support the potential of stem cell therapy as a novel approach in regenerative medicine, offering innovative solutions for men’s health and vitality. Addressing the current limitations and exploring future directions will pave the way for the clinical adoption of stem cell therapy, advancing the treatment options for conditions affecting men’s vitality and improving the quality of life for millions of men worldwide.
Exploring the Role of Stem Cell Therapy in Improving Cognitive and Physical Outcomes for Down Syndrome Patients Pada Vinski, Deby Susanti Pada Vinski; Nugroho, Andi Kurniawan; Vinski, Natasha Cinta; Dollar, Dollar; Gunawan, Dahlan
Journal of World Science Vol. 4 No. 1 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i1.1293

Abstract

This review explores the benefits of Mesenchymal Stem Cell (MSC) therapy concerning Down syndrome (DS), cognitive and behavioral disorders, and other related physiological complications. Two pediatric patients with DS participated in this study, receiving MSC therapy over six months through a qualitative case study approach. Patient A was a 5-year-old male experiencing moderate developmental delays and recurrent infections. Patient B was a 6-year-old female facing mild intellectual disabilities and difficulties in social interaction. The initial and follow-up assessments conducted at baseline, three months, and six months after treatment revealed that patients A and B significantly improved in linguistic abilities, attention, social interactions, and motor coordination. Moreover, enhancing inflammatory indices, such as CRP and IL-6, indicated effective regulation of the immune response and reduced inflammation. Both patients adhered to the therapy without any reported side effects. Thus, the findings highlight the potential neuroprotective and immunomodulatory effects of MSC therapy, suggesting it may serve as a viable adjunct treatment for DS. However, due to the limited number of participants and the relatively short observation period, some limitations, such as the small group size and brief study duration, should be acknowledged, necessitating further larger-scale trials to validate these results and establish protocols. This study adds to the existing literature on MSCs in neurodevelopmental disorders and aims to provide a foundation for exploring new treatment options for DS.
Co-Authors Andi Kurniawan Nugroho Dollar, Dollar Ernandini, Endang Griffin, Darren Gunawan, Dahlan Hardjo, Marhaen Ibnu Hajar, Andi Kurniawan Nugroho, Andi Markus Wibowo Pada Vinski, Deby Susanti Pada Vinski, Deby Susanti Pada Vinski Parish, Elizabeth Pujowaskito, Prihati Quintosa , Jaime Rodriguez Quintosa, Jaime Rodriguez Sinjari, Bruna Susanti Vinski, Deby Trofimova , Svetlana Trofimova, Svetlana Vinski, Deby Susanti Pada Vinski, Deby Susanti Pada Vinski