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All Journal Indonesian Journal of Chemistry Jurnal Layanan Masyarakat (Journal of Public Service) Indian Journal of Forensic Medicine & Toxicology Jurnal Pengabdian Masyarakat Hasanuddin (JPMH)
Suhailah Hayaza
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Humanities Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Environmental Science Public Health Social Sciences Other

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The Antioxidant Effect of Noni Fruits Extract on HDL and LDL Level of Wistar Rat Induced by High Fat Diet Diah Purwaningsari; Sihning EJ Tehupuring; Nita Pranitasari; Suhailah Hayaza; Lestari Dewi; Dian Ardiana
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14704

Abstract

Dyslipidemia is an important risk factor for myocardial infarction, cardiovascular diseases, and Nonalcoholic Fatty Liver (NAFLD) disorders. Inflammatory conditions, oxidative stress, and insulin resistance,as well as several risk factors for cardiovascular disease, are also risk factors for this disease. This study aimsto determine the effect of noni (Morinda citrifolia) extract on the improvement of dyslipidemia condition,based on the Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL) level. This research is alaboratory experimental study with a post-test only control group design. Male Wistar rat (Rattus norvegicus)were divided into four groups: negative control group with no induction and treatment (K-), positive controlgroup given high-fat diet induction for 14 days (K+), noni extract treatment group given a high-fat diet anda noni extract at a dose of 100 mg/kg BB per day for 7 days (P1), and noni extract at a dose of 200 mg/kgBB per day for seven days (P2). Low Density Lipoprotein and High Density Lipoprotein serum levels weremeasured using the ELISA method. The results showed that there was a significant increase in LDL and adecrease in HDL in both treatment groups (P1 and P2) compared with K(+) group. Therefore, we concludethat noni extract (Morinda citrifolia) played a role as an antioxidant which can increase LDL and decreaseHDL serum levels in rats induced by a high fat diet.
APPLICATION OF NANOSENSOR BASED SCREEN PRINTED ELECTRODE FOR ANALYSIS OF ARTIFICIAL SWEETENER FOR PHARMACISTS AND ANALYST IN PONTIANAK Jiwanti, Prastika Krisma; Saputra, Mirza Ardella; Susilo, Raden Joko Kuncoroningrat; Hayaza, Suhailah; Amrillah, Tahta; Firmansyah, Mochamad Lutfi; Amalina, Ilma; Mulya, Fadjar; Rizki, Intan Nurul; Sari, Retno
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 8 No. 3 (2024): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v8i3.2024.339-345

Abstract

The development of nanotechnology in the world is very rapid, and the applications of nanotechnology can be felt in various fields in everyday life. For instance, to control food, nanotechnology plays a role in creating early detection tools for food additives, which are known to be dangerous if consumed by humans in excess, such as the presence of colorants that are not permitted or food additives that exceed tolerance limits. Nanosensors based on screen print electrodes (SPE) are devices that can be used for detection with various notable properties such as fast, sensitive and portable. Seeing the importance of developing and down streaming nanotechnology to society, education regarding the role of nanotechnology needs to be carried out. In this activity, nanotechnology applied in the manufacture of nanosensor devices was introduced, especially to analysts at the drug and food control center and the health service. Apart from that, through this activity, sustainable collaboration can be established between the community service team who are researchers in the field of nanosensors and users in the field who are drug and food regulatory bodies, to develop nanosensor technology according to needs in the field. This activity will be carried out in Pontianak, West Kalimantan, specifically aimed at pharmacists and analysts in the drug and food control center, health service, and industry and trade service (Disperindag). This activity will include education about nanotechnology applications in various fields as well as a demonstration on the use of SPE-based naosensor devices. From this event, in future the analyst may do the analysis in field without waiting long time analysis in laboratory. From this community service activities, scientific articles and publications can be produced in print/electronic media, as well as videos of community service activities, in accordance with the main performance indicators determined nationally.
Deteksi Bahan Tambahan Makanan dan Obat melalui Pendekatan Nanosensor di BPOM Surabaya Amalina, Ilma; Hayaza, Suhailah; Jiwanti, Prastika Krisma; Saputra, Mirza Ardella; Susilo, Raden Joko Kuncoroningrat; Amrillah, Tahta; Firmansyah, Mochammad Lutfi; Mulya, Fadjar; Sari, Retno
Jurnal Pengabdian Masyarakat Hasanuddin (JPMH) Vol 6 No 1 (2025)
Publisher : Universitas Hasanuddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31947/jpmh.v6i1.44257

Abstract

Perkembangan nanoteknologi dalam bidang kesehatan memiliki manfaat yang sangat besar, seperti ditemukaannya material penghantaran obat yang efektif, termasuk juga dalam aplikasi deteksi dini berbagai penyakit, cemaran berbahaya dalam tubuh, maupun lingkungan. Selain itu, dalam upaya pengawasan makanan, nanoteknologi berperan dalam terciptanya alat pendeteksi dini bahan tambahan makanan, yang diketahui berbahaya apabila dikonsumsi oleh manusia secara berlebih, seperti adanya zat warna yang tidak diijinkan maupun kandungan tambahan makanan yang melebihi batas toleransi. Nanosensor berbasis screen printed electrode (SPE) merupakan salah satu teknologi yang dapat digunakan untuk mewujudkan terciptanya rangkaian alat pendeteksi yang cepat, sensitif, dan portable. Pada kegiatan ini, nanoteknologi yang diterapkan pada pembuatan alat nanosensor diperkenalkan khususnya kepada analis yang ada di pusat pengawasan obat dan makanan serta dinas kesehatan, sehingga dapat meningkatkan pengetahuan tim badan pengawas obat dan makanan tentang manfaat nanoteknologi dalam pendeteksian bahan tambahan makanan. Kegiatan ini juga merupakan upaya untuk menjalin kerjasama berkelanjutan antara tim pengabdian masyarakat yang merupakan peneliti dalam bidang nanosensor dengan user di lapangan yang merupakan badan pengawas obat dan makanan, untuk mengembangkan teknologi nanosensor sesuai dengan kebutuhan di lapangan. Kegiatan ini dilaksanakan di Badan Pengawas Obat dan Makanan Surabaya, Jawa Timur. Acara dihadiri oleh 57 apoteker dan analis di lingkungan pusat pengawasan obat dan makanan, dinas kesehatan, serta instansi swasta di Surabaya. Kegiatan ini diisi dengan edukasi tentang aplikasi nanoteknologi diberbagai bidang serta demo penggunaan alat nanosensor berbasis SPE untuk mendeteksi logam berat, antibiotic, dan pewarna makanan. Sebanyak lebih dari 57% peserta menyatakaan sangat puas dengan pelaksanaan kegiatan ini. Dari kegiatan pengabdian masyarakat yang dilakukan dihasilkan artikel ilmiah dan publikasi pada media cetak/elektronik, serta video rangkaian kegiatan pengabdian masyarakat, sesuai dengan indikator kinerja utama yang ditetapkan secara nasional.
Green Synthesis of Selenium Nanoparticles from Okra (Abelmoschus esculentus) Extract with Characterization and Antioxidant Activity Susilo, Raden Joko Kuncoroningrat; Apsari, Retna; Hayaza, Suhailah; Cristian, Yeremia Budi; Prasetyo, Vania Griselda; Widianti, Imanda; Palmasih, Anastasia Alin; Jemon, Khairunadwa; Sajidah, Elma Sakinatus
Indonesian Journal of Chemistry Vol 25, No 4 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.104189

Abstract

Selenium nanoparticles (SeNPs) have gained attention in the medical field because of their enhanced bioactive properties and bioavailability. The green synthesis of nanoparticles offers an eco-friendly synthesis method. In this study, Abelmoschus esculentus (okra) extract was used for the green synthesis of SeNPs. The synthesized SeNPs were characterized using UV-visible (UV-vis), scanning electron microscopy-energy dispersive X-ray (SEM-EDX), Fourier-transform infrared spectroscopy (FTIR), and particle size analyzer (PSA). UV-vis analysis showed a peak at a wavelength of 288 nm, and the SeNPs demonstrated stability at low temperatures for up to 30 days. FTIR analysis indicated interactions between the pectin functional groups on okra and the surface of SeNPs. The SeNPs had a 6.48 nm diameter and polydispersity index of 0.13. A spherical morphology was observed in the nanoparticles. The antioxidant activity of SeNPs was evaluated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) methods. The results showed a dose-dependent increase in free radical inhibition with 31.44 and 15.37% by DPPH and ABTS tests, respectively. The green synthesis of SeNPs using okra extract produced nanoparticles with unique properties based on several characterization results. In conclusion, SeNPs exhibited promising antioxidant activity, highlighting their potential for biomedical applications.
THE USE OF SCREEN PRINTED ELECTRODE-BASED NANOSENSOR TO DETECT DRUGS IN BBPOM DENPASAR, BALI Amrillah, Tahta; Saputra, Mirza Ardella; Jiwanti, Prastika Krisma; Amalina, Ilma; Susilo, Raden Joko Kuncoroningrat; Hayaza, Suhailah; Mulya, Fadjar; Firmansyah, Mochamad Lutfi; Sari, Retno
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 9 No. 4 (2025): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/.v9i4.2025.667-675

Abstract

Nanotechnology sensor is one of technology that could support biomedicine developments, including in the pharmaceutical field. Highly sensitive sensor having ability to detect various pharmaceutical substances as well as components in the food have have been developed, including the so-called nanosensor based screen printed electrode, using nanomaterial boron doped diamond (BDD). This nanosensor could replace conventional sensing technology that is considered still have several drawbacks such as inefficient routes and time consuming, as well as high cost. A nanosensor-based screen printed electrode was developed and implemented for detection of pharmaceutical substances, including drugs. In this opportunity, this community service program disseminated nanosensor technology to pharmacists and food and drug assessors at BBPOM Denpasar, Bali. The program is conducted via short course and practical case on how to use the nanosensor that already developed in the laboratory. The community service program is started with pretest about sensor and nanotechnology, followed by course, practical case, and lastly, the post-test. The post-test results showed a highly positive response, with 71% of participants reporting very high interest, 66% expressing very high satisfaction, and the majority indicating that the activity was relevant, beneficial, and worth recommending. These community service activities are expected to facilitate the broader implementation of nanosensor technology in drug and food assessments. Hopefully, this technology could be spreadly used by the the pharmacies and stake holders who have the right for doing drug and food assessements, not only in Denpasar but also in other cities in Indonesia.
Co-Authors Cristian, Yeremia Budi Diah Purwaningsari Dian Ardiana Fadjar Mulya Firmansyah, Mochamad Lutfi Firmansyah, Mochammad Lutfi Ilma Amalina Intan Nurul Rizki Jemon, Khairunadwa Lestari Dewi Mirza Ardella Saputra Mulya, Fadjar Nita Pranitasari Palmasih, Anastasia Alin Prasetyo, Vania Griselda Prastika Krisma Jiwanti Raden Joko Kuncoroningrat Susilo Retna Apsari Retno Sari Sajidah, Elma Sakinatus Sihning EJ Tehupuring Tahta Amrillah Widianti, Imanda