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A Comparison Study between Green Synthesis of Microwave Irradiation and Solvent Evaporation Methods in The Formation of p-Methoxycinnamic Acid-Succinic Acid Cocrystals Sulistyowaty, Melanny Ika; Setyawan, Dwi; Prameswari, Putu Pradnya Mimba; Susilo, Raden Joko Kuncoroningrat; Amrillah, Tahta; Zaini, Erizal; Zidan, Sabry A. H.
Science and Technology Indonesia Vol. 9 No. 3 (2024): July
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2024.9.3.629-636

Abstract

Cocrystal of p-Methoxycinnamate acid-succinic acid has been produced by microwave irradiation and solvent evaporation methods. Cocrystals are formed using succinic acid as the coformer at a molar ratio of 1:1. The formation of cocrystal can be done by solvent evaporation method and microwave radiation method. Physicochemical properties have been studied by FT-IR, DSC, PXRD, and SEM analysis. The solubility test was carried out with pH 6.8 phosphate buffer at a temperature of 25±0.5°C for 5 hours and the dissolution test was carried out with 900 mL pH 6.8 phosphate buffer at a temperature of 37±0.5°C with the speed of 75 rpm using a paddle-type dissolution test apparatus. The solubility of PMCA has increased its solubility in cocrystals by the solvent evaporation method by 1.19 times and by the microwave radiation method by 1.16 times compared to PMCA. The dissolution rate of the cocrystals of the solvent evaporation method increased by 3.50 times and the cocrystals of the microwave radiation method increased by 2.29 times compared to PMCA.
Peningkatan Nilai Ekonomis Madu melalui Pelatihan Pembuatan Fermented Garlic Honey di Panti Asuhan Al-Madina Surabaya Wulansari, Devyani Diah; Savitri, Emma; Kirtishanti, Aguslina; Wulandari, Devyana Dyah; Susilo, Raden Jokokuncoroningrat; Wuryaningsih, Lucia Endang
Wikrama Parahita : Jurnal Pengabdian Masyarakat Vol. 8 No. 2 (2024): November 2024
Publisher : Universitas Serang Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30656/jpmwp.v8i2.7405

Abstract

Berwirausaha merupakan salah satu upaya yang dapat dilakukan untuk membangkitkan kembali perekonomian Indonesia paska pandemi Covid 19. Untuk dapat mengembangkan usahanya sendiri masyarakat harus dapat melakukan kretifitas yang dapat membuat sesuatu yang baru, berbeda dan dapat mengembangkannya. Grha Aitam merupakan panti asuhan berbasis entrepreneur sebagai konsep pemberdayaan anak yatim dan para dhuafa, berbekal dukungan dari stake holder, khususnya donatur. Salah satu bentuk wirausaha yang ditekuni saat ini berupa pengemasan madu. Hasil dari penggalian informasi dengan mitra, konsumen baru yang ditawarkan madu rata-rata kurang tertarik dengan rasa dan bau madu, serta kurangnya wawasan terkait manfaat madu untuk kesehatan. Melalui program pengabdian kepada masyarakat, solusi yang ditawarkan oleh tim Pengusul kepada Mitra adalah membuat sebuah inovasi produk madu berupa Fermented Garlic Honey (FGH) yang menawarkan rasa dan bau lebih menarik serta unik, serta klaim manfaat kesehatan yang baik, dengan menggunakan aplikasi teknologi fermentasi sehingga dapat dihasilkan produk berkualitas. Program ini diawali dengan evaluasi proses pengemasan madu dengan meninjau kembali layout sarana yang digunakan, kemudian diberikan pengetahuan terkait proses pembuatan serta manfaat medis FGH. Hal ini didukung dengan pengadaan alat fermentasi hingga pada pengemasan serta pengujian laboratorium untuk menganalisis kualitas FGH yang dihasilkan. Melalui serangkaian pelatihan yang difasilitasi oleh Tim, mitra dapat menghasilkan produk FGH yang aman, berkualitas dan berdaya jual tinggi.
APPLICATION OF NANOSENSOR BASED SCREEN PRINTED ELECTRODE FOR ANALYSIS OF ARTIFICIAL SWEETENER FOR PHARMACISTS AND ANALYST IN PONTIANAK Jiwanti, Prastika Krisma; Saputra, Mirza Ardella; Susilo, Raden Joko Kuncoroningrat; Hayaza, Suhailah; Amrillah, Tahta; Firmansyah, Mochamad Lutfi; Amalina, Ilma; Mulya, Fadjar; Rizki, Intan Nurul; Sari, Retno
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 8 No. 3 (2024): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v8i3.2024.339-345

Abstract

The development of nanotechnology in the world is very rapid, and the applications of nanotechnology can be felt in various fields in everyday life. For instance, to control food, nanotechnology plays a role in creating early detection tools for food additives, which are known to be dangerous if consumed by humans in excess, such as the presence of colorants that are not permitted or food additives that exceed tolerance limits. Nanosensors based on screen print electrodes (SPE) are devices that can be used for detection with various notable properties such as fast, sensitive and portable. Seeing the importance of developing and down streaming nanotechnology to society, education regarding the role of nanotechnology needs to be carried out. In this activity, nanotechnology applied in the manufacture of nanosensor devices was introduced, especially to analysts at the drug and food control center and the health service. Apart from that, through this activity, sustainable collaboration can be established between the community service team who are researchers in the field of nanosensors and users in the field who are drug and food regulatory bodies, to develop nanosensor technology according to needs in the field. This activity will be carried out in Pontianak, West Kalimantan, specifically aimed at pharmacists and analysts in the drug and food control center, health service, and industry and trade service (Disperindag). This activity will include education about nanotechnology applications in various fields as well as a demonstration on the use of SPE-based naosensor devices. From this event, in future the analyst may do the analysis in field without waiting long time analysis in laboratory. From this community service activities, scientific articles and publications can be produced in print/electronic media, as well as videos of community service activities, in accordance with the main performance indicators determined nationally.
Deteksi Bahan Tambahan Makanan dan Obat melalui Pendekatan Nanosensor di BPOM Surabaya Amalina, Ilma; Hayaza, Suhailah; Jiwanti, Prastika Krisma; Saputra, Mirza Ardella; Susilo, Raden Joko Kuncoroningrat; Amrillah, Tahta; Firmansyah, Mochammad Lutfi; Mulya, Fadjar; Sari, Retno
Jurnal Pengabdian Masyarakat Hasanuddin (JPMH) Vol 6 No 1 (2025)
Publisher : Universitas Hasanuddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31947/jpmh.v6i1.44257

Abstract

Perkembangan nanoteknologi dalam bidang kesehatan memiliki manfaat yang sangat besar, seperti ditemukaannya material penghantaran obat yang efektif, termasuk juga dalam aplikasi deteksi dini berbagai penyakit, cemaran berbahaya dalam tubuh, maupun lingkungan. Selain itu, dalam upaya pengawasan makanan, nanoteknologi berperan dalam terciptanya alat pendeteksi dini bahan tambahan makanan, yang diketahui berbahaya apabila dikonsumsi oleh manusia secara berlebih, seperti adanya zat warna yang tidak diijinkan maupun kandungan tambahan makanan yang melebihi batas toleransi. Nanosensor berbasis screen printed electrode (SPE) merupakan salah satu teknologi yang dapat digunakan untuk mewujudkan terciptanya rangkaian alat pendeteksi yang cepat, sensitif, dan portable. Pada kegiatan ini, nanoteknologi yang diterapkan pada pembuatan alat nanosensor diperkenalkan khususnya kepada analis yang ada di pusat pengawasan obat dan makanan serta dinas kesehatan, sehingga dapat meningkatkan pengetahuan tim badan pengawas obat dan makanan tentang manfaat nanoteknologi dalam pendeteksian bahan tambahan makanan. Kegiatan ini juga merupakan upaya untuk menjalin kerjasama berkelanjutan antara tim pengabdian masyarakat yang merupakan peneliti dalam bidang nanosensor dengan user di lapangan yang merupakan badan pengawas obat dan makanan, untuk mengembangkan teknologi nanosensor sesuai dengan kebutuhan di lapangan. Kegiatan ini dilaksanakan di Badan Pengawas Obat dan Makanan Surabaya, Jawa Timur. Acara dihadiri oleh 57 apoteker dan analis di lingkungan pusat pengawasan obat dan makanan, dinas kesehatan, serta instansi swasta di Surabaya. Kegiatan ini diisi dengan edukasi tentang aplikasi nanoteknologi diberbagai bidang serta demo penggunaan alat nanosensor berbasis SPE untuk mendeteksi logam berat, antibiotic, dan pewarna makanan. Sebanyak lebih dari 57% peserta menyatakaan sangat puas dengan pelaksanaan kegiatan ini. Dari kegiatan pengabdian masyarakat yang dilakukan dihasilkan artikel ilmiah dan publikasi pada media cetak/elektronik, serta video rangkaian kegiatan pengabdian masyarakat, sesuai dengan indikator kinerja utama yang ditetapkan secara nasional.
Green Synthesis of Selenium Nanoparticles from Okra (Abelmoschus esculentus) Extract with Characterization and Antioxidant Activity Susilo, Raden Joko Kuncoroningrat; Apsari, Retna; Hayaza, Suhailah; Cristian, Yeremia Budi; Prasetyo, Vania Griselda; Widianti, Imanda; Palmasih, Anastasia Alin; Jemon, Khairunadwa; Sajidah, Elma Sakinatus
Indonesian Journal of Chemistry Vol 25, No 4 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.104189

Abstract

Selenium nanoparticles (SeNPs) have gained attention in the medical field because of their enhanced bioactive properties and bioavailability. The green synthesis of nanoparticles offers an eco-friendly synthesis method. In this study, Abelmoschus esculentus (okra) extract was used for the green synthesis of SeNPs. The synthesized SeNPs were characterized using UV-visible (UV-vis), scanning electron microscopy-energy dispersive X-ray (SEM-EDX), Fourier-transform infrared spectroscopy (FTIR), and particle size analyzer (PSA). UV-vis analysis showed a peak at a wavelength of 288 nm, and the SeNPs demonstrated stability at low temperatures for up to 30 days. FTIR analysis indicated interactions between the pectin functional groups on okra and the surface of SeNPs. The SeNPs had a 6.48 nm diameter and polydispersity index of 0.13. A spherical morphology was observed in the nanoparticles. The antioxidant activity of SeNPs was evaluated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) methods. The results showed a dose-dependent increase in free radical inhibition with 31.44 and 15.37% by DPPH and ABTS tests, respectively. The green synthesis of SeNPs using okra extract produced nanoparticles with unique properties based on several characterization results. In conclusion, SeNPs exhibited promising antioxidant activity, highlighting their potential for biomedical applications.
SYNTHESIS AND CHARACTERIZATION OF CHITOSAN MEMBRANES OF CASSAVA PEEL (Manihot esculenta) AND LERI STARCH COMBINATION AS A BIODEGRADABLE PLASTIC: English Dewi, Pande Putu Indira Prima; Widhiantara, I Gede; Sandhika, I Made Gde Sudyadnyana; Wiradana, Putu Angga; Susilo, Raden Joko Kuncoroningrat
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 1 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.3080

Abstract

Problems related to landfills of plastic packaging waste are a source of environmental pollution. This research provides innovation in utilizing biodegradable plastic from cassava and leri peel starch with the addition of chitosan. This study aimed to analyze the results of the synthesis and characterization of chitosan membranes with a combination of cassava and leri peel starch and determine the biodegradation time of biodegradable plastic in EM-4 bioactivation. This study characterized biodegradable plastic membranes using test parameters, namely the SEM, FTIR, Swelling, and tensile strength tests. The biodegradation test was carried out by immersing biodegradable plastic membranes in an EM-4 bioactator for 7 days. Based on the results obtained from the characterization of biodegradable plastic membranes, namely the swelling test with concentrations of 5:3, 7:3, and 9:3, with yield values ​​of 62.9921%, 69.8902%, and 71.4286%. The SEM test obtained the best results at a concentration of 7:3. FTIR test on biodegradable plastic membranes containing hydroxyl (O-H) and carbonyl (C-O) groups. The tensile test obtained optimum results at the concentration of biodegradable plastic membranes, namely 9:3. As for the biodegradation test that has been carried out, the start time for degradation is 3 days.
SYNTHESIS AND CHARACTERIZATION OF CHITOSAN MEMBRANES OF CASSAVA PEEL (Manihot esculenta) AND LERI STARCH COMBINATION AS A BIODEGRADABLE PLASTIC: English Dewi, Pande Putu Indira Prima; Widhiantara, I Gede; Sandhika, I Made Gde Sudyadnyana; Wiradana, Putu Angga; Susilo, Raden Joko Kuncoroningrat
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 1 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.3080

Abstract

Problems related to landfills of plastic packaging waste are a source of environmental pollution. This research provides innovation in utilizing biodegradable plastic from cassava and leri peel starch with the addition of chitosan. This study aimed to analyze the results of the synthesis and characterization of chitosan membranes with a combination of cassava and leri peel starch and determine the biodegradation time of biodegradable plastic in EM-4 bioactivation. This study characterized biodegradable plastic membranes using test parameters, namely the SEM, FTIR, Swelling, and tensile strength tests. The biodegradation test was carried out by immersing biodegradable plastic membranes in an EM-4 bioactator for 7 days. Based on the results obtained from the characterization of biodegradable plastic membranes, namely the swelling test with concentrations of 5:3, 7:3, and 9:3, with yield values ​​of 62.9921%, 69.8902%, and 71.4286%. The SEM test obtained the best results at a concentration of 7:3. FTIR test on biodegradable plastic membranes containing hydroxyl (O-H) and carbonyl (C-O) groups. The tensile test obtained optimum results at the concentration of biodegradable plastic membranes, namely 9:3. As for the biodegradation test that has been carried out, the start time for degradation is 3 days.