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All Journal Majalah Kedokteran Nusantara The Journal Of Medical School Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Jurnal Respirasi (JR) Sumatera Medical Journal
Siregar, Kamal Basri
Department Of General Medicine, Faculty Of Medical, Universitas Sumatera Utara, Medan, Indonesia
Agriculture, Biological Sciences & Forestry Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Journal : Sumatera Medical Journal

 1 
Apoptotic Index Fails to Predict Chemoresponse in Breast Cancer Siregar, Kamal Basri
Sumatera Medical Journal Vol. 2 No. 2 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (675.446 KB) | DOI: 10.32734/sumej.v2i2.1062

Abstract

The responsiveness of neoadjuvant chemotherapy in Triple Negative Breast Cancer (TNBC) needs determination to prevent overtreatment with chemoresistance regimen. A total of 60 consented patients from Haji Adam Malik and Bunda Thamrin Hospital were included in this cohort prospectie study. Patients with heart, kidney, liver disease, history of surgery, chemotherapy, or hormonal therapy were excluded. Apoptotic indexes were taken from all subjects before and after neoadjuvant chemotherapy. After 3 cycles of neoadjuvant chemotherapy, 31 subjects (51.7%) did not show clinical response while 29 subjects (48.3%) had clinical response. There was no significant difference of apoptotic index before and after neoadjuvant chemotherapy (5.47+1.38 vs 5.52+1.08 pg/mL). There was also no significant relationship between apoptosis index and clinical response (p=0.993). This study showed that apoptotic index fails to be neoadjuvant chemotherapy response predictor in triple negative breast cancer. Further research with larger samples is needed to confirm this result
Cancer-Related Visits to the Emergency Department: Trends and Patient Characteristics at Adam Malik General Hospital Medan Basri Siregar, Kamal; Rahayu, Yolanda; Suganda, Yongki; Andrea, Aze
Sumatera Medical Journal Vol. 6 No. 3 (2023): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v6i3.12830

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Background: The prevalence of cancer cases globally is increasing rapidly, especially in emergency department (ED) visits. Usually, cancer patients come for acute signs and symptoms of a still undiagnosed malignancy, management of treatment-related side effects, co-morbidities, and palliative care. Objective: To identify the demographic characteristics of cancer patients, reasons for ED visits, and associated factors of oncologic patients. Methods: A prospective cross-sectional study was conducted from July 2022 - June 2023 at the ED of H. Adam Malik Hospital Medan with 392 oncologic patients. Data were collected using the Integrated System Application of Hospital (STARS) database. Results: The percentage of women (69%) was two times higher than men (31%), with 82% being 18- 64 years old. Breast was the most common location of malignancy for 21.4%, followed by gastrointestinal malignancy for 20.1%. The most common reason for ED visits was pain, followed by gastrointestinal symptoms. The ratio of patients who were discharged and hospitalized was 50:50, while the mortality rate was none. Conclusion: The most common primary diagnosis was breast malignancy in women and gastrointestinal malignancy in men. The majority of ED visits were for the management of treatment-related side effects and palliative care.
Frequency Distribution of Oncology Patients Who Come to Emergency Department at H. Adam Malik Hospital, Medan Basri Siregar, Kamal; Manik, David Restu; Hakim, Luqmanul; Gultom, Habib Solihin; Naqib bin Md Ghazali, Muhammad
Sumatera Medical Journal Vol. 7 No. 3 (2024): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v7i3.13698

Abstract

Background: A multidisciplinary approach is needed to comprehensively evaluate cancer patient’s condition and understanding patient demographic characteristics can improve health care by adapting to each patient's needs. Objective: The aim of this study was to explore about frequency distribution of oncolohy patients. Methods: This research is a descriptive observational study with a cross-sectional study design conducted at the Haji Adam Malik General Hospital in Medan on oncology patients who met the inclusion criteria. Data with a numerical measuring scale will be presented in mean+standard deviation (SD) and data with a categorical measuring scale will be presented in frequencies and percentages. Results: The results showed that majority of patients were in 46–59 year age group as much as 32 patients (37.2%) and 58 patients (67.4%) were female. The highest level of education was found in 26 patients (30.2%) as bachelor, and 45 patients (52.3%) lived in Medan City. Most patients came to be treated at the surgical installation as many as 50 patients (25.6%). Conclusion: The research results found that majority of patients are in the age group 46-59 years, female, bachelor, domicile in Medan and are treated in surgical installation.
Co-Authors Andrea, Aze Ariantika, Ariantika Asfriyati ,MKes Gema Nazri Yanni Gema Nazri Yanni Gultom, Habib Solihin Lim, Darren Wan-Teck Luqmanul Hakim Manik, David Restu Naqib bin Md Ghazali, Muhammad Noni Novisari Soeroso Nuraiza Meutia Nurmaini Nurmaini Rahayu Lubis Rahayu, Yolanda Santer dr Suganda, Yongki Suyatno dr Taufik Ashar Yetty Machrina Yunita Sari Pane