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All Journal Paediatrica Indonesiana Majalah Kedokteran Nusantara The Journal Of Medical School SCRIPTA SCORE Scientific Medical Journal Cermin Dunia Kedokteran Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) The Journal of Society Medicine (JSOCMED) Cermin Dunia Kedokteran
Arto, Karina Sugih
Department Of Child Health University Of Sumatera Utara Medical School/H. Adam Malik Hospital, Medan, North Sumatera
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Correlation between Glycated Hemoglobin and Calcium Levels in Pediatric with Type 1 Diabetes Mellitus Nasution, Indah; Arto, Karina Sugih; Lubis, Bugis Mardina
Journal of Society Medicine Vol. 2 No. 11 (2023): November
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v2i11.101

Abstract

Introduction: Type 1 diabetes mellitus is a systemic disorder resulting from impaired glucose metabolism characterized by chronic hyperglycemia. Caused by damage to pancreatic β cells either by autoimmune or idiopathic processes resulting in reduced or even halted insulin production. Diabetes mellitus is associated with a decrease in calcium with impaired intestinal calcium absorption and hypercalciuria which causes a decrease in calcium absorption into the body. Method: This study used a prospective study method to assess the correlation between HbA1C levels and calcium levels in children with type 1 diabetes mellitus. This research was conducted  in the Endocrinology Outpatient Unit of Haji Adam Malik Hospital Medan, May 2022 to December 2022. The samples were children aged 1 month to 18 years. Results: Correlation is measured using Pearson correlation analysis for normally distributed data while Spearman correlation is used for data that was not normally distributed. There is a significant correlation between the HbA1c and calcium levels with a p value of 0.026 and a correlation value of (r= -0.445). The correlation value is negative, meaning that every increase in HbA1c levels will be followed by a decrease in serum calcium levels in children with type I diabetes, with moderate strength (r= 0.4 – 0.6). This effect is not influenced by diseases duration and onset of diabetes. Conclusion: There is a decrease in calcium in type 1 diabetes
Correlation between Leptin and Free Testosterone Levels in Transfusion-Dependent Thalassemia Male Patients Lubis, Dian Anindita; Karina Sugih Arto; Heny Syahrini
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 1 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i1.12159

Abstract

Background: Male hypogonadism is a clinical disorder of low testosterone and spermatozoa due to impaired production that can occur at one or more levels in the hypothalamic-pituitary-gonadal (HPG) axis. Apart from iron accumulation, hypogonadism can also occur due to other mechanisms in thalassemia patients, such as the influence of adipose tissue and leptin. The study aimed to assess the relationship between leptin with free testosterone levels and BMI in transfusion-dependent thalassemia. Method: The research design chosen was analytic cross-sectional. The study was conducted at the adult thalassemia polyclinic of Cipto Mangunkusumo General Hospital and Fatmawati General Hospital, during the period July - December 2022. The samples used were male transfusion-dependent thalassemia patients aged over 18 years who were under control at the Thalassemia Polyclinic during the study period. The diagnosis of Thalassemia had been previously established by high-performance liquid chromatography (HPLC) or microcapillary examination. Result: Most patients were major ß thalassemia (87.8%), while HbE ß thalassemia was only 12.1%. Age distribution was with a median of 23 years (minimum-maximum 18-42 years). The clinical symptoms of hypogonadism were erectile dysfunction and decreased libido (12.1% and 9%, respectively). From body mass index examination were underweight 18 (54,5%), normal weight 13 (39,5%), overweight 1 (3%), and obese 1 (3%). Of the 33 transfusion-dependent thalassemia patients, 95% did not reach puberty according to their age (Tanner stage V). Conclusion: There is an association significantly between leptin levels with free testosterone and body mass index in transfusion-dependent thalassemia men.
Kontrol Metabolik pada Diabetes Melitus Tipe-1 Miranda Adelita; Karina Sugih Arto; Melda Deliana
Cermin Dunia Kedokteran Vol 47 No 3 (2020): Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v47i3.360

Abstract

Diabetes melitus (DM) tipe-1 adalah kondisi yang disebabkan oleh kerusakan sel-β pankreas baik oleh proses autoimun maupun idiopatik, sehingga produksi insulin berkurang atau berhenti. DM tipe-1 sampai saat ini belum dapat disembuhkan, tetapi kualitas pertumbuhan dan perkembangan anak dan remaja dapat dipertahankan seoptimal mungkin dengan upaya kontrol metabolik dengan baik. Untuk tujuan tersebut, diperlukan komponen pengelolaan DM tipe-1 yang terdiri dari lima pilar terintegrasi meliputi pemberian insulin, nutrisi, olahraga, dan edukasi didukung oleh pemantauan secara mandiri. Kontrol metabolik yang baik adalah mengusahakan kadar glukosa darah berada dalam batas normal atau mendekati nilai normal, tanpa menyebabkan hipoglikemia dengan target kontrol HbA1c <7%. Type-1 diabetes mellitus (DM) is a condition caused by pancreatic β-cell damage either by an autoimmune or idiopathic process resulting reduced or stopped insulin production. Type-1 DM can not be cured yet but the quality of growth and development of children and adolescents can be maintained optimally by metabolic control. These goals and objectives can be achieved through type-1 DM management that consists of integrated five pillars including insulin, nutrition, exercise, education, and supported by independent monitoring. Good metabolic control is to keep blood glucose levels within normal limits or close to normal values, without causing hypoglycemia. HbA1c <7% is a target of good metabolic control.
Hubungan Pengetahuan Anak tentang Cuci Tangan dengan Kejadian Diare di Desa Panobasan Harahap, Nurul Wahida; Arto, Karina Sugih; Supriatmo; Dalimunthe, Dina Arwina
SCRIPTA SCORE Scientific Medical Journal Vol. 2 No. 1 (2020): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v2i1.3392

Abstract

Background: Diarrhea is a condition in which feces are discharged from the bowel in loose consistency or even liquid form, and the frequency is usually more often ( usually three times or more) in one day. Non-hygienic lifestyles, such as not washing hands before consuming food and after doing activities can cause negative impact to health, particularly the occurrence of diseases that related to poor sanitation, such as diarrhea. The prevalence are more common by 10 % in rural areas compared to 7.4% in urban areas. Incidence rate in diarrhea tends to be higher in group with lower education whom work as farmer, fisherman, or labor. Objectives: This study aims to analyze the relationship of childrend`s knowledge about hand washing and diarrhea occurence. Methods: This study is an  analytic study with a cross sectional design. The data is primary data that were collected directly from respondents through questionnaire. The respondents were chosen by stratified random sampling method. Results: From data of 35 respondents, the p-value 0.005 ( p <0.05), PR value 0.364 ( 0.177 – 0.749). Conclusion: There is a significant relationship between childrend`s knowledge about hand washing with diarrhea in Panobasan village. Keywords: children's knowledge, diarrhea, hand washing     Latar Belakang: Diare adalah suatu kondisi dimana seseorang buang air besar dengan konsistensi lembek atau cair, bahkan dapat berupa air saja dan frekuensinya lebih sering (biasanya tiga kali atau lebih) dalam satu hari. Kebiasaan kurang higienis berupa tidak mencuci tangan sebelum makan atau tidak mencuci tangan setelah melakukan aktivitas yang berhubungan dengan lingkungan dapat menimbulkan dampak negatif bagi kesehatan masyarakat, terutama munculnya penyakit yang berkaitan dengan perilaku hidup bersih dan sehat yang rendah salah satunya yaitu diare. Prevalensi diare lebih banyak di pedesaan dibandingkan perkotaan, yaitu sebesar 10% di pedesaan dan 7,4 % di perkotaan. Diare cenderung lebih tinggi pada kelompok pendidikan rendah dan bekerja sebagai petani, nelayan dan buruh. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan anak tentang cuci tangan dengan kejadian diare. Metode: Penelitian ini merupakan studi penelitian analitik dengan desain penelitian cross sectional, metode pengumpulan data penelitian ini adalah data primer, yaitu data yang diperoleh langsung dari sampel menggunakan kuesioner. Sampel dalam penelitian ini diperoleh dengan menggunakan cara stratified random sampling. Hasil: Dari 135 responden, hubungan pengetahuan anak tentang cuci tangan dengan kejadian diare didapatkan hasil  dengan nilai p = 0,005 (p < 0,05), dan nilai PR = 0,364 (0,177 – 0,749). Kesimpulan: Terdapat hubungan yang signifikan antara pengetahauan anak tentang cuci tangan dengan kejadian diare di desa Panobasan. Kata kunci: cuci tangan, diare, pengetahuan anak
Co-Authors Adelita, Miranda Bagus Prastyo, Dimas Bugis Mardina Lubis, Bugis Mardina Dina Arwina Dalimunthe, Dina Arwina Erna Mutiara Hakimi dr Hakimi Hakimi Harahap, Nurul Wahida Hariadi Edi Saputra Heny Syahrini Jose Rizal Latief Batubara Jose RL Batubara Lubis, Dian Anindita Mayasari Lubis, Siska Melda Deliana Melda Deliana Melda Deliana Melda Deliana Melda Deliana Melda Deliana, Melda Miranda Adelita Munar Lubis Nasution, Indah Purba, Siska Octaviani Rahmad Sumiko Rina Amalia C. Saragih, Rina Amalia C. Rina Amalia Karomina Saragih Rizki Aryo Wicaksono Rizki Aryo Wicaksono Siska Mayasari Lubis Siska Mayasari Lubis Sufitni Supriatmo Whyra Pratama Said Winra Pratita