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All Journal Sari Pediatri Indonesian Journal of Global Health research Cermin Dunia Kedokteran The Journal of Society Medicine (JSOCMED)
Bugis Mardina Lubis, Bugis Mardina
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Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health

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Analisis Gas Darah dan Laktat Darah Tali Pusat sebagai Parameter Metabolik pada Asfiksia Perinatal Sitanggang, Fitri Parinda; Lubis, Bugis Mardina; Dimyati, Yazid; Tjipta, Guslihan Dasa; Syofiani, Beby; Sianturi, Pertin; Lubis, Syamsidah; Wahyuni, Fera
Cermin Dunia Kedokteran Vol 46, No 9 (2019): Neuropati
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (588.827 KB) | DOI: 10.55175/cdk.v46i9.437

Abstract

Asfiksia masih merupakan salah satu penyebab utama kematian neonatus per tahun. Skor Apgar dapat memberikan informasi vitalitas neonatus namun memiliki beberapa keterbatasan. Asfiksia perinatal dapat muncul dari berbagai risiko intrapartum dan postpartum yang mengakibatkan terhentinya pertukaran gas pada fetus. Metabolisme anaerob akan menyebabkan akumulasi laktat dan penurunan pH. Analisis asam-basa dan laktat darah tali pusat dapat memberikan penilaian objektif terhadap status metabolik neonatus.Asphyxia still remain a major causes of neonatal death per year. Apgar score provides information on neonatal vitality but has several limitations. Perinatal asphyxia can arise from a variety of intrapartum and postpartum risks which result in cessation of gas exchange. Anaerobic metabolism will cause lactate accumulation and pH decrease. Analysis of acid-base and lactate in cord blood can provide an objective assessment of the metabolic status of the neonate. 
Peran D-Dimer sebagai Penanda Sepsis Neonatorum Brahmana, Annette Regina; Lubis, Bugis Mardina; Ali, Muhammad
Cermin Dunia Kedokteran Vol 47, No 2 (2020): Penyakit Infeksi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.22 KB) | DOI: 10.55175/cdk.v47i2.357

Abstract

Sepsis merupakan penyebab utama morbiditas dan mortalitas neonatal. Disfungsi koagulasi merupakan komplikasi sepsis neonatorum yang dapat bermanifestasi klinis atau subklinis pada koagulasi intravaskular. D-dimer merupakan hasil degradasi fibrin ikat silang yang meningkat pada sepsis.Sepsis is a major cause of neonatal morbidity and mortality. Coagulation dysfunction is a complication that can manifest clinically or subclinically in intravascular coagulation. D-dimer, a cross-linked fibrin degradation product, is increased in neonates with sepsis. 
Correlation between Glycated Hemoglobin and Calcium Levels in Pediatric with Type 1 Diabetes Mellitus Nasution, Indah; Arto, Karina Sugih; Lubis, Bugis Mardina
Journal of Society Medicine Vol. 2 No. 11 (2023): November
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v2i11.101

Abstract

Introduction: Type 1 diabetes mellitus is a systemic disorder resulting from impaired glucose metabolism characterized by chronic hyperglycemia. Caused by damage to pancreatic β cells either by autoimmune or idiopathic processes resulting in reduced or even halted insulin production. Diabetes mellitus is associated with a decrease in calcium with impaired intestinal calcium absorption and hypercalciuria which causes a decrease in calcium absorption into the body. Method: This study used a prospective study method to assess the correlation between HbA1C levels and calcium levels in children with type 1 diabetes mellitus. This research was conducted  in the Endocrinology Outpatient Unit of Haji Adam Malik Hospital Medan, May 2022 to December 2022. The samples were children aged 1 month to 18 years. Results: Correlation is measured using Pearson correlation analysis for normally distributed data while Spearman correlation is used for data that was not normally distributed. There is a significant correlation between the HbA1c and calcium levels with a p value of 0.026 and a correlation value of (r= -0.445). The correlation value is negative, meaning that every increase in HbA1c levels will be followed by a decrease in serum calcium levels in children with type I diabetes, with moderate strength (r= 0.4 – 0.6). This effect is not influenced by diseases duration and onset of diabetes. Conclusion: There is a decrease in calcium in type 1 diabetes
Analisis Hubungan Tingkat Pendidikan dengan Tingkat Pengetahuan Ibu tentang Stunting dan Faktor Risiko di Kecamatan Medan Denai Elfrida, Anastasya Valentine; Lubis, Bugis Mardina; Ramayani, Oke Rina; Sitorus, Mega Sari
Sari Pediatri Vol 26, No 3 (2024)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp26.3.2024.171-5

Abstract

Latar belakang. Stunting merupakan kondisi gagal tumbuh akibat kekurangan gizi secara kronis. Di Indonesia, prevalensi stunting pada tahun 2021 adalah 24,4 persen. Kondisi prevalensi stunting di Sumatera Utara juga sangat memprihatinkan. Sebanyak 13 dari 33 kabupaten/kota yang berada di Sumatera Utara memiliki prevalensi stunting di atas 30%. Kecamatan Medan Denai adalah salah satu kecamatan di Kota Medan dengan kasus gizi buruk anak tertinggi. Salah satu faktor risiko kejadian stunting adalah tingkat pendidikan ibu.Tujuan. Penelitian ini bertujuan untuk mengetahui hubungan tingkat pendidikan dengan tingkat pengetahuan ibu tentang stunting.Metode. Penelitian analitik observasional dengan desain cross-sectional dengan sampel penelitian terdiri dari 96 responden yaitu ibu anak balita yang berdomisili dan menyekolahkan anaknya di TK/PAUD di Kecamatan Medan Denai yang memenuhi kriteria inklusi dan eksklusi. Analisis data menggunakan uji statistik chi-square.Hasil. Pada 96 responden ditemukan tingkat pengetahuan tentang stunting yang sedang (60,4%), rendah (30,2%), dan tinggi (9,4%). Hasil analisis menunjukkan terdapat hubungan yang signifikan antara tingkat pendidikan dengan tingkat pengetahuan ibu tentang stunting dengan nilai p=0,035 (p<0,05).Kesimpulan. Mayoritas ibu memiliki tingkat pengetahuan tentang stunting yang sedang dan terdapat hubungan yang signifikan antara tingkat pendidikan dengan tingkat pengetahuan ibu tentang stunting.
Infection Markers as Prediction of Neonatal Sepsis Sirait, Cindy Clarissa; Lubis, Bugis Mardina; Tanjung, Ika Citra Dewi; Wijaya, Hendri; Wahyuni, Arlinda Sari; Pasaribu, Ayodhia Pitaloka
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.6066

Abstract

Neonatal sepsis is one of the most common causes of neonatal death in the first month of life. Neonatal sepsis often shows atypical clinical features include temperature instability, lethargy, skin changes, feeding problems, and many others. Isolation of bacteria from the culture is the gold standard for diagnosing sepsis, but this approach is frequently time-consuming and even in cases of negative blood cultures, sepsis cannot be conclusively ruled out, posing a major challenge in its diagnosis and management. Early diagnosis and timely intervention are essential to improve the prognosis of neonatal sepsis. Aim: The aim of this study is to discuss how infection markers can aid in the early identification of neonatal sepsis and what are the best infection markers to predict neonatal sepsis mortality. Method: This study assessed the diagnostic accuracies of infection marker used in the diagnosis of neonatal sepsis. Included studies were retrieved by searching three major databases (Google Scholar, Pubmed, and Science Direct) using MeSH words and relevant references, and reviewed based on the inclusion/exclusion criteria. The article discusses potential advancements and future prospects for biomarkers. An excellent marker can guide antibiotic administration and duration if sepsis is confirmed, reducing unnecessary use. The marker should have high sensitivity, specificity, positive predictive value, negative predictive value and accuracy.
Co-Authors Arto, Karina Sugih Beby Syofiani, Beby Brahmana, Annette Regina Dimyati, Yazid Elfrida, Anastasya Valentine Guslihan Dasa Tjipta, Guslihan Dasa Hendri Wijaya, Hendri MUHAMMAD ALI Nasution, Indah Oke Rina Ramayani, Oke Rina Pasaribu, Ayodhia Pitaloka Pertin Sianturi Sirait, Cindy Clarissa Sitanggang, Fitri Parinda Sitorus, Mega Sari Syamsidah Lubis, Syamsidah Tanjung, Ika Citra Dewi Wahyuni, Arlinda Sari Wahyuni, Fera