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The Effect of Administering Omega-3 Supplements on Serum Lipopolysaccharide (LPS) Levels in Schizophrenia Patients Who Are Taking Atypical Antipsychotics in the Psychiatric Hospital of Prof HB Saanin Padang Sri Mulyanti; Sulastri, Delmi; Amel Yanis; Masrul; Rauza Sukma Rita; Ilmiawati
Jurnal Psikiatri Surabaya Vol. 13 No. 2 (2024): November
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v13i2.55121

Abstract

Introduction: Schizophrenia is a severe mental disorder that ranks among the top 10 major contributors to global disability. Schizophrenia is a disorder of brain function in the form of impaired perception, thoughts, feelings, cognitive processes, and behavior. They require long-term atypical antipsychotics for therapy, but they have secondary effects on food intake and cause intestinal dysbiosis, one of which is characterized by increased serum lipolysaccharide (LPS) levels. We aim to examine the impact of omega-3 supplementation on serum LPS levels in schizophrenia patients utilizing atypical antipsychotics. Methods: This research is an experiment with a randomized pretest-posttest control group design and a triple-blind study in Prof. HB Saanin Padang’s psychiatric hospital and the Biomedic Laboratory, Faculty of Medicine, Andalas University, from July 2023 to February 2024. The research sample consisted of 15 individuals who received 1000 mg Omega-3 PUFA (180 mg EPA and 120 mg DHA) daily for 21 days, and another 15 individuals who served as the control group. We checked the serum LPS levels using ELISA in duplicate on days 0 and 22. We analyzed the data using the paired t-test. Results: There was a significant difference in serum LPS levels in schizophrenia patients taking atypical antipsychotics before and after being given omega-3 supplements in the inpatient ward of Prof. HB Saanin Mental Hospital Padang with p = 0.02 (p < 0.05). Conclusion: Omega-3 supplement 1000 mg/day can reduce serum LPS levels in schizophrenia patients who receive atypical antipsychotic therapy.
Effectiveness of Catering Owners' Knowledge in Early Warning of Food Poisoning Outbreaks in Medan City Rapida Saragih; Dasman, Hardisman; Indrapriyatna, Ahmad Syafruddin; Yani, Finny Fitry; Lipoeto, Nur Indrawaty; Yetti, Husna; Ilmiawati; Harun, Harnavi
proceedinginternational Vol. 5 (2025): Proceeding International Conference 15th Desember 2024
Publisher : POLTEKKES KEMENKES PADANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33761/jd.v5i.53

Abstract

Food poisoning outbreaks are a serious problem that can have a significant impact on public health. Food poisoning occurs when food consumed is contaminated with bacteria, viruses, parasites, or hazardous chemicals. Medan City experiences fluctuating food poisoning incidents, so continuous monitoring is needed to identify and address the causes. The purpose of this study was to determine early warning by using a module to prevent food poisoning outbreaks. This study was conducted quantitatively using an experimental design with the one group pretest-posttest design (before and after) approach. The location of the study was carried out at the Medan City Health Office and a population of 20 respondents, while the sample, namely the total population, was the sample. The data obtained were analyzed univariately, bivariately. The results showed that knowledge in catering owners with n = 20, paired sample T-test there was a significant difference between the level of knowledge of respondents about food poisoning before and after the intervention using the module p value = 0.0001 (<0.05). The module that has been developed and validated by language experts with results of 94.3, material experts with 97.3 and media experts with 91.3 can effectively prevent poisoning. It is recommended to the local Health Service and Health Center to be able to use the module as an early warning model for food poisoning outbreaks, especially for catering business owners, so that they can increase knowledge, especially in carrying out prevention. Keywords: Knowledge, Early Warning, Outbreak, Food Poisoning.
Connection Age with Behavior use Method Contraception Long Term in Active KB Acceptors in the Family Planning Village Program in Sungai Penuh City Kiran Nandini; Vaulline Basyir; Firdawati; Rima Semiarty; Syamel Muhammad; Ilmiawati
Indonesian Journal of Advanced Research Vol. 3 No. 2 (2024): February 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijar.v3i2.8252

Abstract

The Long Term Contraceptive Method (MKJP) is an effective contraceptive method used to plan, postpone, and terminate pregnancy. MKJP is considered effective because the failure rate is low compared to non-MKJP contraception. The factor of couples of childbearing age in using contraception cannot be separated from the behavioral factors of each individual. This research aims to determine the relationship between age and the behavior of using MKJP among active family planning acceptors in the family planning village program in Sungai Penuhcity. The design of this research is a cross-sectional study. The sample in this study was 354 people. Data was collected using a questionnaire and analyzed using chi-square. The research results showed a relationship between age (p= 0.003) and MKJP usage behavior.