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All Journal Borneo Journal Of Pharmascientech Ruhui Rahayu: Jurnal Pengabdian Kepada Masyarakat
Sarwo, Laura
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Humanities Chemistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Other

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Formulasi Microneedle Acne Patch Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L.) Fitriana, Mia; Sarwo, Laura; Maharani, Ni Ayu
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 2 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i2.574

Abstract

Belimbing wuluh leaves (Averrhoa bilimbi L.) contain flavonoids, saponins, and tannins that can be used as antibacterials in acne treatments. Acne treatment requires good delivery so that it can penetrate into the epidermis. A preparation that can deliver active substances directly into the epidermis is a microneedle patch (MN) preparation. This study aimed to formulate a microneedle acne patch of ethanol extract of A. bilimbi leaves. A. bilimbi leaves were extracted using maceration method. MN preparation base was optimized using different base combinations namely Na-CMC:PVA, HPMC: PVA and PVP:PVA until the ideal MN base was obtained. The MN preparations obtained were tested for physico-chemical properties which included macroscopic tests, weight uniformity, drying shrinkage, pH, folding power and moisture absorption. MN optimization results showed that the combination of PVP and PVA formed a flexible MN base and needle. Formulation was then continued by varying the concentration of extracts in the MN. The results of the physical and chemical properties test of the MN preparation formula showed flexible characteristics, homogeneous and no bubbles in MN, yellow to blackish green in color, weights ranging from 0,063-0,163 g, drying shrinkage of 3.349-4.513%, pH in the range of 5.61-7.15, folding power >300x, and moisture absorption of 6.472%-8.33%. The conclusion of the study showed that the MN preparation formulas of A. bilimbi extract, namely F1, F2, F3 and F4 meet the requirements of good physico-chemical MN preparations.
Aktivitas Antibakteri Sediaan Microneedle Acne Patch Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa bilimbi Linn) terhadap Staphylococcus epidermidis Fitriana, Mia; Sarwo, Laura; Wathan, Nashrul
BORNEO JOURNAL OF PHARMASCIENTECH Vol 9 No 1 (2025): Borneo Journal Of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59053/bjp.v9i1.658

Abstract

Acne is often accompanied by inflammation and triggers antibacterial activity such as S. Epidermidis. A. Bilimbi folium are known to inhibit the growth of S. Epidermidis. Microneedle (MN) is a preparation with small needles measuring 50-900 μm that can be applied to deliver active ingredients for acne treatment. The effect of concentration of A. Bilimbi MN acne patch leaf extract can cause changes in antibacterial activity. The purpose of this study was to determine the effect of the concentration of ethanol extract of A. Bilimbi folium on MN acne patch preparation on the inhibition of S. Epidermidis. The research was conducted by making 5 MN formulas with different extract concentrations and then testing the antibacterial activity with agar diffusion method. The negative control used was the formula without extracts while the positive control used chloramphenicol and acne patch preparation on the market. The results showed the clear zone of F1 (1%), F2 (5%), F3 (10%), F4 (15%), F5 (20%) of 1.86±0.485 mm; 3.15±0.556 mm; 5±0.526 mm; 8.25±0.687 mm; 9.43±0.809 mm, respectively. The conclusion of this study is that there was an effect of the concentration of ethanol extract of A. Bilimbi folium in the preparation of microneedle acne patches on the antibacterial activity of S. Epidermidis.
EDUKASI PENGGUNAAN OBAT DI BULAN PUASA DI INSTALASI FARMASI RUMAH SAKIT DAERAH IDAMAN BANJARBARU: Drug Use Education in the Fasting Month at the Pharmacy Installation of the Idaman Regional Hospital Banjarbaru Winda Tri Kurniasari; Sarwo, Laura; Nadila Sari; Nasya Hafizah; Nurul Mardiati; Soraya, Ayu
Jurnal Ruhui Rahayu: Jurnal Pengabdian Masyarakat Ilmu Humaniora Vol 4 No 2 (2025)
Publisher : Program Studi Sastra Indonesia Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/ruhuirahayu.v4i2.217

Abstract

Abstract: The pattern of medication consumption during Ramadan, which previously could be done throughout the day, must be adjusted to only within a range of approximately 10.5 hours each day. Therefore, adjustments are needed in the medication schedule so that the effectiveness of the treatment is as expected. The method used for health education is participatory education using PowerPoint (PPT) media. The PPT media contains accurate, interesting, and interactive information so that listeners can focus on the information being presented. Health education on “Medication Use During Fasting Month” was held at the Outpatient Pharmacy Depot of the Idaman Banjarbaru Regional General Hospital on Monday, March 10, 2025, from 10:00 to 10:30 a.m. WITA, ending with an open discussion through a question and answer session. Based on the discussion results, many patients were unaware of the proper rules for taking medication during the fasting month, and patients also felt afraid that using special medical devices during fasting might invalidate their fast. Keywords: Health Education, Ramadhan, Fasting, Drug use   Abstrak: Pola konsumsi obat di bulan Ramadhan yang sebelumnya dapat dilakukan sepanjang hari harus disesuaikan menjadi hanya dalam rentang waktu sekitar 10,5 jam setiap harinya. Oleh karena itu, diperlukan penyesuaian dalam jadwal penggunaan obat agar efektivitas pengobatan sesuai dengan yang diharapkan. Metode yang digunakan saat edukasi kesehatan adalah metode edukasi partisipatif dengan media Power Point (PPT). Media PPT berisi informasi yang akurat serta menarik dan interaktif sehingga pendengar dapat fokus terhadap informasi yang sedang diberikan. Edukasi kesehatan mengenai “Penggunaan Obat di Bulan Puasa” dilaksanakan di Depo Rawat Jalan Instalasi Farmasi RSD Idaman Banjarbaru pada hari Senin, 10 Maret 2025 pukul 10.00-10.30 WITA yang diakhiri dengan diskusi terbuka melalui sesi tanya jawab. Berdasarkan hasil diskusi, banyak pasien yang belum mengetahui terkait aturan minum obat yang tepat di bulan puasa dan pasien juga merasa takut jika melakukan pengobatan dengan alat khusus selama berpuasa akan membatalkan puasa. Kata kunci: Edukasi Kesehatan, Ramadhan, Puasa, Penggunaan obat
Co-Authors Maharani, Ni Ayu Mia Fitriana Nadila Sari Nashrul Wathan Nasya Hafizah Nurul Mardiati Soraya, Ayu Winda Tri Kurniasari